Chemical Formula: C10H15NO3
Chemical Formula C10H15NO3
Found 145 metabolite its formula value is C10H15NO3
Metanephrine
Metanephrine is a metabolite of epinephrine created by action of catechol O-methyltransferase on epinephrine. Technically it is a product of epinephrine O-methylation. It is a commonly occurring, pharmacologically and physiologically inactive metabolite of epinephrine. The measurement of plasma free metanephrines is considered to be the best tool in the diagnosis of pheochromocytoma, a rare kind of adrenal medullary neoplasm. In adrenal chromaffin cells, leakage of norepinephrine and epinephrine from storage granules leads to substantial intracellular production of the O-methylated metabolite metanephrine. In fact, the adrenals constitute the single largest source out of any organ system including the liver for circulating metanephrine. In humans, about 93 percent of circulating metanephrine is derived from catecholamines metabolized within adrenal chromaffin cells. (PMID 15317907). Metanephrine is a metabolite of epinephrine created by action of catechol O-methyltransferase on epinephrine. Technically it is a product of epinephrine O-methylation. It is a commonly occurring, pharmacologically and physiologically inactive metabolite of epinephrine. The measurement of plasma free metanephrines is considered to be the best tool in the diagnosis of pheochromocytoma, a rare kind of adrenal medullary neoplasm.
Tenuazonic acid
Tenuazonic acid is produced by Aspergillus species Causes rice leaf rot Tenuazonic acid is a mycotoxin. It is a toxic secondary metabolite, produced by Alternaria (e. g. Alternaria alternata or Alternaria tenuis) and Phoma species. It inhibits the protein synthesis machinery D000890 - Anti-Infective Agents > D000998 - Antiviral Agents D009676 - Noxae > D011042 - Poisons > D009183 - Mycotoxins Production by Aspergillus subspecies Causes rice leaf rot D000970 - Antineoplastic Agents
Methyl 8-methyl-3-oxo-8-azabicyclo[3.2.1]octane-2-carboxylate
Desglymidodrine
Desglymidodrine is a metabolite of midodrine. Midodrine (brand names Amatine, ProAmatine, Gutron) is a vasopressor/antihypotensive agent. Midodrine was approved in the United States by the Food and Drug Administration (FDA) in 1996 for the treatment of dysautonomia and orthostatic hypotension. In August 2010, the FDA proposed withdrawing this approval because the manufacturer, Shire plc, has failed to complete required studies after the medicine reached the market. (Wikipedia) Midodrine, a prodrug, is converted after oral administration into its active drug, desglymidodrine, which acts as an alpha(1)-adrenoceptor stimulant. (PMID: 17901021) Through selective alpha(1)-adrenergic receptor-binding, desglymidodrine, the active metabolite of midodrine, raises blood pressure by enhancing venous and arterial tone. (PMID: 12904123) Desglymidodrine (ST 1059), the active metabolite of Midodrine (HY-12749), is a selective α1-adrenoceptor agonist. Desglymidodrine is an effective arterial and venous vasoconstrictor and can be used to regulate blood pressure[1][2].
L-Metanephrine
L-Metanephrine is classified as a member of the Methoxyphenols. Methoxyphenols are compounds containing a methoxy group attached to the benzene ring of a phenol moiety. L-Metanephrine is considered to be soluble (in water) and acidic
1,2-octadienoylglycine
1,2-Octadienoylglycine is classified as a member of the Alpha amino acids. Alpha amino acids are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon). 1,2-Octadienoylglycine is considered to be practically insoluble (in water) and acidic.
1,3-octadienoylglycine
1,3-Octadienoylglycine is classified as a member of the Alpha amino acids. Alpha amino acids are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon). 1,3-Octadienoylglycine is considered to be practically insoluble (in water) and acidic.
1,4-octadienoylglycine
1,4-Octadienoylglycine is classified as a member of the Alpha amino acids. Alpha amino acids are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon). 1,4-Octadienoylglycine is considered to be slightly soluble (in water) and acidic.
1,5-octadienoylglycine
1,5-Octadienoylglycine is classified as a member of the Alpha amino acids. Alpha amino acids are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon). 1,5-Octadienoylglycine is considered to be slightly soluble (in water) and acidic.
1,6-octadienoylglycine
1,6-Octadienoylglycine is classified as a member of the Alpha amino acids. Alpha amino acids are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon). 1,6-Octadienoylglycine is considered to be slightly soluble (in water) and acidic.
1,7-octadienoylglycine
1,7-Octadienoylglycine is classified as a member of the Alpha amino acids. Alpha amino acids are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon). 1,7-Octadienoylglycine is considered to be slightly soluble (in water) and acidic.
2,3-octadienoylglycine
2,3-octadienoylglycine is classified as a member of the n-acyl-alpha amino acids. N-acyl-alpha amino acids are compounds containing an alpha amino acid which bears an acyl group at its terminal nitrogen atom. 2,3-octadienoylglycine is considered to be a practically insoluble (in water) and a weak acidic compound. 2,3-octadienoylglycine can be found in urine.
2,4-octadienoylglycine
2,4-Octadienoylglycine is classified as a member of the N-acyl-alpha amino acids. N-acyl-alpha amino acids are compounds containing an alpha amino acid which bears an acyl group at its terminal nitrogen atom. 2,4-Octadienoylglycine is considered to be practically insoluble (in water) and acidic.
2,5-octadienoylglycine
2,5-Octadienoylglycine is classified as a member of the N-acyl-alpha amino acids. N-acyl-alpha amino acids are compounds containing an alpha amino acid which bears an acyl group at its terminal nitrogen atom. 2,5-Octadienoylglycine is considered to be practically insoluble (in water) and acidic.
2,6-octadienoylglycine
2,6-Octadienoylglycine is classified as a member of the N-acyl-alpha amino acids. N-acyl-alpha amino acids are compounds containing an alpha amino acid which bears an acyl group at its terminal nitrogen atom. 2,6-Octadienoylglycine is considered to be practically insoluble (in water) and acidic.
2,7-octadienoylglycine
2,7-Octadienoylglycine is classified as a member of the N-acyl-alpha amino acids. N-acyl-alpha amino acids are compounds containing an alpha amino acid which bears an acyl group at its terminal nitrogen atom. 2,7-Octadienoylglycine is considered to be practically insoluble (in water) and acidic.
3,4-octadienoylglycine
3,4-Octadienoylglycine is classified as a member of the N-acyl-alpha amino acids. N-acyl-alpha amino acids are compounds containing an alpha amino acid which bears an acyl group at its terminal nitrogen atom. 3,4-Octadienoylglycine is considered to be practically insoluble (in water) and acidic.
3,5-octadienoylglycine
3,5-Octadienoylglycine is classified as a member of the N-acyl-alpha amino acids. N-acyl-alpha amino acids are compounds containing an alpha amino acid which bears an acyl group at its terminal nitrogen atom. 3,5-Octadienoylglycine is considered to be practically insoluble (in water) and acidic.
3,6-octadienoylglycine
3,6-Octadienoylglycine is classified as a member of the N-acyl-alpha amino acids. N-acyl-alpha amino acids are compounds containing an alpha amino acid which bears an acyl group at its terminal nitrogen atom. 3,6-Octadienoylglycine is considered to be practically insoluble (in water) and acidic.
3,7-octadienoylglycine
3,7-Octadienoylglycine is classified as a member of the N-acyl-alpha amino acids. N-acyl-alpha amino acids are compounds containing an alpha amino acid which bears an acyl group at its terminal nitrogen atom. 3,7-Octadienoylglycine is considered to be practically insoluble (in water) and acidic.
4,5-octadienoylglycine
4,5-Octadienoylglycine is classified as a member of the N-acyl-alpha amino acids. N-acyl-alpha amino acids are compounds containing an alpha amino acid which bears an acyl group at its terminal nitrogen atom. 4,5-Octadienoylglycine is considered to be practically insoluble (in water) and acidic.
4,6-octadienoylglycine
4,6-Octadienoylglycine is classified as a member of the N-acyl-alpha amino acids. N-acyl-alpha amino acids are compounds containing an alpha amino acid which bears an acyl group at its terminal nitrogen atom. 4,6-Octadienoylglycine is considered to be practically insoluble (in water) and acidic.
4,7-octadienoylglycine
4,7-Octadienoylglycine is classified as a member of the N-acyl-alpha amino acids. N-acyl-alpha amino acids are compounds containing an alpha amino acid which bears an acyl group at its terminal nitrogen atom. 4,7-Octadienoylglycine is considered to be practically insoluble (in water) and acidic.
5,6-octadienoylglycine
5,6-Octadienoylglycine is classified as a member of the N-acyl-alpha amino acids. N-acyl-alpha amino acids are compounds containing an alpha amino acid which bears an acyl group at its terminal nitrogen atom. 5,6-Octadienoylglycine is considered to be practically insoluble (in water) and acidic.
5,7-octadienoylglycine
5,7-Octadienoylglycine is classified as a member of the N-acyl-alpha amino acids. N-acyl-alpha amino acids are compounds containing an alpha amino acid which bears an acyl group at its terminal nitrogen atom. 5,7-Octadienoylglycine is considered to be practically insoluble (in water) and acidic.
6,7-octadienoylglycine
6,7-Octadienoylglycine is classified as a member of the N-acyl-alpha amino acids. N-acyl-alpha amino acids are compounds containing an alpha amino acid which bears an acyl group at its terminal nitrogen atom. 6,7-Octadienoylglycine is considered to be practically insoluble (in water) and acidic.
Tenuazonic acid-(Copper salt)
ethyl 3-oxo-2-azabicyclo[2.2.2]octane-4-carboxylate
(S)-5-(1-hydroxybutyl)-6-(hydroxymethyl)pyridin-2(1H)-one|chrysogedone B
Ethylnorepinephrine
C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent
tenuazonic acid
A member of the class of pyrrolidin-2-ones that is 5-(butan-2-yl)pyrrolidine-2,4-dione carrying an additional acetyl group at position 3. A mycotoxin produced by various plant pathogenic fungi. D000890 - Anti-Infective Agents > D000998 - Antiviral Agents D009676 - Noxae > D011042 - Poisons > D009183 - Mycotoxins CONFIDENCE Reference Standard (Level 1) D000970 - Antineoplastic Agents
Ethyl 3-oxo-8-azabicyclo[3.2.1]octane-8-carboxylate
3-Cyclohexene-1-carboxylicacid,1-(acetylamino)-,methylester(9CI)
tert-butyl 3-oxo-2,6-dihydropyridine-1-carboxylate
Methyl (2Z)-2-(cyclopropylcarbonyl)-3-(dimethylamino)acrylate
tert-butyl 3-ethynyl-3-hydroxyazetidine-1-carboxylate
5-(2-Methylpropyl)-3-isoxazolecarboxylic acid ethyl ester
Ethyl 6-oxo-2-azabicyclo[2.2.2]octane-2-carboxylate
TERT-BUTYL 2-OXO-5,6-DIHYDROPYRIDINE-1(2H)-CARBOXYLATE
methyl 1-[(E)-but-2-enoyl]pyrrolidine-2-carboxylate
4-[1-methoxy-2-(methylamino)ethyl]benzene-1,2-diol
(3R,7aS)-3-(tert-butyl)dihydro-1H,3H-pyrrolo[1,2-c]oxazole-1,5(6H)-dione
4-AMINOMETHYL-2,5-DIMETHYL-FURAN-3-CARBOXYLIC ACID ETHYL ESTER
1-Cyclopentene-1-carboxylicacid,2-[[(1-methylethyl)amino]carbonyl]-(9CI)
METHYL 4-(HYDROXYMETHYL)-1,2,5-TRIMETHYL-1H-PYRROLE-3-CARBOXYLATE
4-HYDROXYMETHYL-3,5-DIMETHYL-1H-PYRROLE-2-CARBOXYLIC ACID ETHYL ESTER
4-Oxo-3,4-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester
1-(2-methoxyethyl)-2,5-dimethylpyrrole-3-carboxylic acid
ethyl 6-oxo-3-azabicyclo[3.2.1]octane-3-carboxylate
Chrysogedone B
A pyridone that is pyridin-2(1H)-one substituted by a hydroxymethyl group at position 6 and a 1-hydroxybutyl group at position 5. It has been isolated from Penicillium chrysogenum.
3-Acetyl-4-hydroxy-5-(2-methylpropyl)-1,5-dihydro-2H-pyrrol-2-one
Ecgonone methyl ester
The methyl ester of (1R,2R,5S)-8-methyl-3-oxo-8-azabicyclo[3.2.1]octane-2-carboxylic acid (ecgonone).
4-[(1R)-2-(dimethylamino)-1-hydroxyethyl]benzene-1,2-diol
DESGLYMIDODRINE
Desglymidodrine (ST 1059), the active metabolite of Midodrine (HY-12749), is a selective α1-adrenoceptor agonist. Desglymidodrine is an effective arterial and venous vasoconstrictor and can be used to regulate blood pressure[1][2].