Exact Mass: 575.2373
Exact Mass Matches: 575.2373
Found 477 metabolites which its exact mass value is equals to given mass value 575.2373
,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Zafirlukast
Zafirlukast is an oral leukotriene receptor antagonist (LTRA) for the maintenance treatment of asthma, often used in conjunction with an inhaled steroid and/or long-acting bronchodilator. It is available as a tablet and is usually dosed twice daily. Another leukotriene receptor antagonist is montelukast (Singulair), which is usually taken just once daily. Zafirlukast blocks the action of the cysteinyl leukotrienes on the CysLT1 receptors, thus reducing constriction of the airways, build-up of mucus in the lungs and inflammation of the breathing passages. R - Respiratory system > R03 - Drugs for obstructive airway diseases > R03D - Other systemic drugs for obstructive airway diseases > R03DC - Leukotriene receptor antagonists D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents > D020024 - Leukotriene Antagonists D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006727 - Hormone Antagonists C78273 - Agent Affecting Respiratory System > C29712 - Anti-asthmatic Agent
Pro-phe-arg-mca
Ejap 14
O-alpha-D-glucopyranosyl-(1<*>4)-O-2-acetamido-2-deoxy-alpha-D-glucopyranosyl-(1<*>2)-D-glycero-L-manno-heptose|O-alpha-D-glucopyranosyl-(1[*]4)-O-2-acetamido-2-deoxy-alpha-D-glucopyranosyl-(1[*]2)-D-glycero-L-manno-heptose
4,6,10-Triacetoxy-5a-(acetoxymethyl)-3,4,5,5a,6,7,8,9-octahydro-2,2,9-trimethyl-5-(3-pyridylcarbonyloxy)-2H-3,9a-methano-1-benzooxepin
His Glu Tyr Lys
Thr His Tyr Arg
zafirlukast
R - Respiratory system > R03 - Drugs for obstructive airway diseases > R03D - Other systemic drugs for obstructive airway diseases > R03DC - Leukotriene receptor antagonists D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents > D020024 - Leukotriene Antagonists D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006727 - Hormone Antagonists C78273 - Agent Affecting Respiratory System > C29712 - Anti-asthmatic Agent
Ala His Trp Tyr
Ala His Tyr Trp
Ala Asn Trp Trp
Ala Trp His Tyr
Ala Trp Asn Trp
Ala Trp Trp Asn
Ala Trp Tyr His
Ala Tyr His Trp
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Cys His Met Trp
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Cys Lys Tyr Tyr
Cys Met His Trp
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Cys Gln Tyr Tyr
Cys Trp His Met
Cys Trp Met His
Cys Tyr Lys Tyr
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Cys Tyr Tyr Lys
Cys Tyr Tyr Gln
Asp Lys Gln Trp
Asp Lys Trp Gln
Asp Gln Lys Trp
Asp Gln Gln Trp
Asp Gln Trp Lys
Asp Gln Trp Gln
Asp Trp Lys Gln
Asp Trp Gln Lys
Asp Trp Gln Gln
Glu Glu Ile Trp
Glu Glu Leu Trp
Glu Glu Trp Ile
Glu Glu Trp Leu
Glu His Lys Tyr
Glu His Gln Tyr
Glu His Tyr Lys
Glu His Tyr Gln
Glu Ile Glu Trp
Glu Ile Trp Glu
Glu Lys His Tyr
Glu Lys Asn Trp
Glu Lys Trp Asn
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Glu Leu Glu Trp
Glu Leu Trp Glu
Glu Asn Lys Trp
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Glu Asn Trp Lys
Glu Asn Trp Gln
Glu Gln His Tyr
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Glu Trp Glu Ile
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Glu Trp Ile Glu
Glu Trp Lys Asn
Glu Trp Leu Glu
Glu Trp Asn Lys
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Glu Tyr His Lys
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Gly Lys Trp Trp
Gly Gln Trp Trp
Gly Trp Lys Trp
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Gly Trp Trp Lys
Gly Trp Trp Gln
His Ala Trp Tyr
His Ala Tyr Trp
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His Cys Trp Met
His Glu Lys Tyr
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His Glu Tyr Gln
His Phe Ser Trp
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His Tyr Glu Lys
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Ile Glu Glu Trp
Ile Glu Trp Glu
Ile Trp Glu Glu
Lys Cys Tyr Tyr
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Lys Glu His Tyr
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Lys Gly Trp Trp
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Lys Asn Glu Trp
Lys Asn Trp Glu
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Lys Trp Glu Asn
Lys Trp Gly Trp
Lys Trp Asn Glu
Lys Trp Gln Asp
Lys Trp Trp Gly
Lys Tyr Cys Tyr
Lys Tyr Glu His
Lys Tyr His Glu
Lys Tyr Tyr Cys
Leu Glu Glu Trp
Leu Glu Trp Glu
Leu Trp Glu Glu
Met Cys His Trp
Met Cys Trp His
Met His Cys Trp
Met His Trp Cys
Met Trp Cys His
Met Trp His Cys
Asn Ala Trp Trp
Asn Glu Lys Trp
Asn Glu Gln Trp
Asn Glu Trp Lys
Asn Glu Trp Gln
Asn Lys Glu Trp
Asn Lys Trp Glu
Asn Gln Glu Trp
Asn Gln Trp Glu
Asn Arg Thr Trp
Asn Arg Trp Thr
Asn Thr Arg Trp
Asn Thr Trp Arg
Asn Trp Ala Trp
Asn Trp Glu Lys
Asn Trp Glu Gln
Asn Trp Lys Glu
Asn Trp Gln Glu
Asn Trp Arg Thr
Asn Trp Thr Arg
Asn Trp Trp Ala
Pro His His Trp
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Gln Cys Tyr Tyr
Gln Asp Lys Trp
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Gln Trp Asp Lys
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Gln Trp Glu Asn
Gln Trp Gly Trp
Gln Trp Lys Asp
Gln Trp Asn Glu
Gln Trp Gln Asp
Gln Trp Arg Ser
Gln Trp Ser Arg
Gln Trp Trp Gly
Gln Tyr Cys Tyr
Gln Tyr Glu His
Gln Tyr His Glu
Gln Tyr Tyr Cys
Arg His Thr Tyr
Arg His Tyr Thr
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Arg Thr His Tyr
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Arg Trp Asn Thr
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Ser Phe His Trp
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Trp Ala His Tyr
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Trp Cys His Met
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Trp His Cys Met
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Trp His Pro His
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Trp Ile Glu Glu
Trp Lys Asp Gln
Trp Lys Glu Asn
Trp Lys Gly Trp
Trp Lys Asn Glu
Trp Lys Gln Asp
Trp Lys Trp Gly
Trp Leu Glu Glu
Trp Met Cys His
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Trp Asn Lys Glu
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Trp Asn Arg Thr
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Trp Pro His His
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Trp Gln Gly Trp
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Trp Gln Asn Glu
Trp Gln Gln Asp
Trp Gln Arg Ser
Trp Gln Ser Arg
Trp Gln Trp Gly
Trp Arg Asn Thr
Trp Arg Gln Ser
Trp Arg Ser Gln
Trp Arg Thr Asn
Trp Ser Phe His
Trp Ser His Phe
Trp Ser Gln Arg
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Trp Thr Arg Asn
Trp Trp Ala Asn
Trp Trp Gly Lys
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Trp Tyr Ala His
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Tyr Cys Lys Tyr
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Tandospirone Citrate
D002492 - Central Nervous System Depressants > D014149 - Tranquilizing Agents > D014151 - Anti-Anxiety Agents D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D014149 - Tranquilizing Agents D018377 - Neurotransmitter Agents > D018490 - Serotonin Agents > D017366 - Serotonin Receptor Agonists D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants C78272 - Agent Affecting Nervous System > C28197 - Antianxiety Agent C78272 - Agent Affecting Nervous System > C47794 - Serotonin Agonist Tandospirone citrate is a potent and selective 5-HT1A receptor partial agonist (Ki = 27 nM) that displays selectivity over SR-2, SR-1C, α1, α2, D1 and D2 receptors (Ki values ranging from 1300-41000 nM). IC50 Value: 27±5 nM(Ki) [1] Target: 5-HT1A in vitro: Tandospirone is most potent at the 5-HT1A receptor, displaying a Ki value of 27 +/- 5 nM. The agent is approximately two to three orders of magnitude less potent at 5-HT2, 5-HT1C, alpha 1-adrenergic, alpha 2-adrenergic, and dopamine D1 and D2 receptors (Ki values ranging from 1300 to 41000 nM). Tandospirone is essentially inactive at 5-HT1B receptors; 5-HT uptake sites; beta-adrenergic, muscarinic cholinergic, and benzodiazepine receptors [1]. 3H-SM-3997 bound rapidly, reversibly and in a saturable manner with high affinity to rat brain hippocampal membranes (Kd = 9.4 nM, Bmax = 213 fmol/mg protein) [2]. in vivo: Chronic treatment with tandospirone, at 0.2 and 1.0mg/kg/day, but not 2.0mg/kg/day, attenuated footshock stress-induced eLAC elevation in the mPFC [3]. Rats were acutely administered tandospirone (0, 0.1, and 1 mg/kg, i.p.). Tandospirone decreased the number of premature responses, an index of impulsive action, in a dose-dependent manner [4]. Toxicity: It is not believed to be addictive but it is known to produce mild withdrawal effects (e.g. anorexia) after abrupt discontinuation.
(4r)-3-{(2s,3s)-2-Hydroxy-3-[(3-Hydroxy-2-Methylbenzoyl)amino]-4-Phenylbutanoyl}-5,5-Dimethyl-N-(2-Methylbenzyl)-1,3-Thiazolidine-4-Carboxamide
Aripiprazole cavoxil
C78272 - Agent Affecting Nervous System > C29710 - Antipsychotic Agent