Exact Mass: 575.2286
Exact Mass Matches: 575.2286
Found 380 metabolites which its exact mass value is equals to given mass value 575.2286
,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Zafirlukast
Zafirlukast is an oral leukotriene receptor antagonist (LTRA) for the maintenance treatment of asthma, often used in conjunction with an inhaled steroid and/or long-acting bronchodilator. It is available as a tablet and is usually dosed twice daily. Another leukotriene receptor antagonist is montelukast (Singulair), which is usually taken just once daily. Zafirlukast blocks the action of the cysteinyl leukotrienes on the CysLT1 receptors, thus reducing constriction of the airways, build-up of mucus in the lungs and inflammation of the breathing passages. R - Respiratory system > R03 - Drugs for obstructive airway diseases > R03D - Other systemic drugs for obstructive airway diseases > R03DC - Leukotriene receptor antagonists D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents > D020024 - Leukotriene Antagonists D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006727 - Hormone Antagonists C78273 - Agent Affecting Respiratory System > C29712 - Anti-asthmatic Agent
Ejap 14
O-alpha-D-glucopyranosyl-(1<*>4)-O-2-acetamido-2-deoxy-alpha-D-glucopyranosyl-(1<*>2)-D-glycero-L-manno-heptose|O-alpha-D-glucopyranosyl-(1[*]4)-O-2-acetamido-2-deoxy-alpha-D-glucopyranosyl-(1[*]2)-D-glycero-L-manno-heptose
4,6,10-Triacetoxy-5a-(acetoxymethyl)-3,4,5,5a,6,7,8,9-octahydro-2,2,9-trimethyl-5-(3-pyridylcarbonyloxy)-2H-3,9a-methano-1-benzooxepin
His Glu Tyr Lys
zafirlukast
R - Respiratory system > R03 - Drugs for obstructive airway diseases > R03D - Other systemic drugs for obstructive airway diseases > R03DC - Leukotriene receptor antagonists D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents > D020024 - Leukotriene Antagonists D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006727 - Hormone Antagonists C78273 - Agent Affecting Respiratory System > C29712 - Anti-asthmatic Agent
Ala His Trp Tyr
Ala His Tyr Trp
Ala Asn Trp Trp
Ala Trp His Tyr
Ala Trp Asn Trp
Ala Trp Trp Asn
Ala Trp Tyr His
Ala Tyr His Trp
Ala Tyr Trp His
Cys His Met Trp
Cys His Trp Met
Cys Lys Tyr Tyr
Cys Met His Trp
Cys Met Trp His
Cys Gln Tyr Tyr
Cys Trp His Met
Cys Trp Met His
Cys Tyr Lys Tyr
Cys Tyr Gln Tyr
Cys Tyr Tyr Lys
Cys Tyr Tyr Gln
Asp Lys Gln Trp
Asp Lys Trp Gln
Asp Gln Lys Trp
Asp Gln Gln Trp
Asp Gln Trp Lys
Asp Gln Trp Gln
Asp Trp Lys Gln
Asp Trp Gln Lys
Asp Trp Gln Gln
Glu Glu Ile Trp
Glu Glu Leu Trp
Glu Glu Trp Ile
Glu Glu Trp Leu
Glu His Lys Tyr
Glu His Gln Tyr
Glu His Tyr Lys
Glu His Tyr Gln
Glu Ile Glu Trp
Glu Ile Trp Glu
Glu Lys His Tyr
Glu Lys Asn Trp
Glu Lys Trp Asn
Glu Lys Tyr His
Glu Leu Glu Trp
Glu Leu Trp Glu
Glu Asn Lys Trp
Glu Asn Gln Trp
Glu Asn Trp Lys
Glu Asn Trp Gln
Glu Gln His Tyr
Glu Gln Asn Trp
Glu Gln Trp Asn
Glu Gln Tyr His
Glu Trp Glu Ile
Glu Trp Glu Leu
Glu Trp Ile Glu
Glu Trp Lys Asn
Glu Trp Leu Glu
Glu Trp Asn Lys
Glu Trp Asn Gln
Glu Trp Gln Asn
Glu Tyr His Lys
Glu Tyr His Gln
Glu Tyr Lys His
Glu Tyr Gln His
Phe His Ser Trp
Phe His Trp Ser
Phe Ser His Trp
Phe Ser Trp His
Phe Trp His Ser
Phe Trp Ser His
Gly Gln Trp Trp
Gly Trp Gln Trp
Gly Trp Trp Gln
His Ala Trp Tyr
His Ala Tyr Trp
His Cys Met Trp
His Cys Trp Met
His Glu Lys Tyr
His Glu Gln Tyr
His Glu Tyr Gln
His Phe Ser Trp
His Phe Trp Ser
His His Pro Trp
His His Trp Pro
His Lys Glu Tyr
His Lys Tyr Glu
His Met Cys Trp
His Met Trp Cys
His Pro His Trp
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His Gln Glu Tyr
His Gln Tyr Glu
His Ser Phe Trp
His Ser Trp Phe
His Trp Ala Tyr
His Trp Cys Met
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His Trp Met Cys
His Trp Pro His
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His Trp Tyr Ala
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His Tyr Glu Lys
His Tyr Glu Gln
His Tyr Lys Glu
His Tyr Gln Glu
His Tyr Trp Ala
Ile Glu Glu Trp
Ile Glu Trp Glu
Ile Trp Glu Glu
Lys Cys Tyr Tyr
Lys Asp Gln Trp
Lys Asp Trp Gln
Lys Glu His Tyr
Lys Glu Asn Trp
Lys Glu Trp Asn
Lys Glu Tyr His
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Lys His Tyr Glu
Lys Asn Glu Trp
Lys Asn Trp Glu
Lys Gln Asp Trp
Lys Gln Trp Asp
Lys Trp Asp Gln
Lys Trp Glu Asn
Lys Trp Asn Glu
Lys Trp Gln Asp
Lys Tyr Cys Tyr
Lys Tyr Glu His
Lys Tyr His Glu
Lys Tyr Tyr Cys
Leu Glu Glu Trp
Leu Glu Trp Glu
Leu Trp Glu Glu
Met Cys His Trp
Met Cys Trp His
Met His Cys Trp
Met His Trp Cys
Met Trp Cys His
Met Trp His Cys
Asn Ala Trp Trp
Asn Glu Lys Trp
Asn Glu Gln Trp
Asn Glu Trp Lys
Asn Glu Trp Gln
Asn Lys Glu Trp
Asn Lys Trp Glu
Asn Gln Glu Trp
Asn Gln Trp Glu
Asn Trp Ala Trp
Asn Trp Glu Lys
Asn Trp Glu Gln
Asn Trp Lys Glu
Asn Trp Gln Glu
Asn Trp Trp Ala
Pro His His Trp
Pro His Trp His
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Gln Cys Tyr Tyr
Gln Asp Lys Trp
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Gln Asp Trp Lys
Gln Asp Trp Gln
Gln Glu His Tyr
Gln Glu Asn Trp
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Gln Gly Trp Trp
Gln His Glu Tyr
Gln His Tyr Glu
Gln Lys Asp Trp
Gln Lys Trp Asp
Gln Asn Glu Trp
Gln Asn Trp Glu
Gln Gln Asp Trp
Gln Gln Trp Asp
Gln Trp Asp Lys
Gln Trp Asp Gln
Gln Trp Glu Asn
Gln Trp Gly Trp
Gln Trp Lys Asp
Gln Trp Asn Glu
Gln Trp Gln Asp
Gln Trp Trp Gly
Gln Tyr Cys Tyr
Gln Tyr Glu His
Gln Tyr His Glu
Gln Tyr Tyr Cys
Ser Phe His Trp
Ser Phe Trp His
Ser His Phe Trp
Ser His Trp Phe
Ser Trp Phe His
Ser Trp His Phe
Trp Ala His Tyr
Trp Ala Asn Trp
Trp Ala Trp Asn
Trp Ala Tyr His
Trp Cys His Met
Trp Cys Met His
Trp Asp Lys Gln
Trp Asp Gln Lys
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Trp Glu Glu Ile
Trp Glu Glu Leu
Trp Glu Ile Glu
Trp Glu Lys Asn
Trp Glu Leu Glu
Trp Glu Asn Lys
Trp Glu Asn Gln
Trp Glu Gln Asn
Trp Phe His Ser
Trp Phe Ser His
Trp Gly Gln Trp
Trp Gly Trp Gln
Trp His Ala Tyr
Trp His Cys Met
Trp His Phe Ser
Trp His His Pro
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Trp His Pro His
Trp His Ser Phe
Trp His Tyr Ala
Trp Ile Glu Glu
Trp Lys Asp Gln
Trp Lys Glu Asn
Trp Lys Asn Glu
Trp Lys Gln Asp
Trp Leu Glu Glu
Trp Met Cys His
Trp Met His Cys
Trp Asn Ala Trp
Trp Asn Glu Lys
Trp Asn Glu Gln
Trp Asn Lys Glu
Trp Asn Gln Glu
Trp Asn Trp Ala
Trp Pro His His
Trp Gln Asp Lys
Trp Gln Asp Gln
Trp Gln Glu Asn
Trp Gln Gly Trp
Trp Gln Lys Asp
Trp Gln Asn Glu
Trp Gln Gln Asp
Trp Gln Trp Gly
Trp Ser Phe His
Trp Ser His Phe
Trp Trp Ala Asn
Trp Trp Gly Gln
Trp Trp Asn Ala
Trp Trp Gln Gly
Trp Tyr Ala His
Trp Tyr His Ala
Tyr Ala His Trp
Tyr Ala Trp His
Tyr Cys Lys Tyr
Tyr Cys Gln Tyr
Tyr Cys Tyr Lys
Tyr Cys Tyr Gln
Tyr Glu His Lys
Tyr Glu His Gln
Tyr Glu Lys His
Tyr Glu Gln His
Tyr His Ala Trp
Tyr His Glu Lys
Tyr His Glu Gln
Tyr His Lys Glu
Tyr His Gln Glu
Tyr His Trp Ala
Tyr Lys Cys Tyr
Tyr Lys Glu His
Tyr Lys His Glu
Tyr Lys Tyr Cys
Tyr Gln Cys Tyr
Tyr Gln Glu His
Tyr Gln His Glu
Tyr Gln Tyr Cys
Tyr Trp Ala His
Tyr Trp His Ala
Tyr Tyr Cys Lys
Tyr Tyr Cys Gln
Tyr Tyr Lys Cys
Tyr Tyr Gln Cys
Tandospirone Citrate
D002492 - Central Nervous System Depressants > D014149 - Tranquilizing Agents > D014151 - Anti-Anxiety Agents D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D014149 - Tranquilizing Agents D018377 - Neurotransmitter Agents > D018490 - Serotonin Agents > D017366 - Serotonin Receptor Agonists D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants C78272 - Agent Affecting Nervous System > C28197 - Antianxiety Agent C78272 - Agent Affecting Nervous System > C47794 - Serotonin Agonist Tandospirone citrate is a potent and selective 5-HT1A receptor partial agonist (Ki = 27 nM) that displays selectivity over SR-2, SR-1C, α1, α2, D1 and D2 receptors (Ki values ranging from 1300-41000 nM). IC50 Value: 27±5 nM(Ki) [1] Target: 5-HT1A in vitro: Tandospirone is most potent at the 5-HT1A receptor, displaying a Ki value of 27 +/- 5 nM. The agent is approximately two to three orders of magnitude less potent at 5-HT2, 5-HT1C, alpha 1-adrenergic, alpha 2-adrenergic, and dopamine D1 and D2 receptors (Ki values ranging from 1300 to 41000 nM). Tandospirone is essentially inactive at 5-HT1B receptors; 5-HT uptake sites; beta-adrenergic, muscarinic cholinergic, and benzodiazepine receptors [1]. 3H-SM-3997 bound rapidly, reversibly and in a saturable manner with high affinity to rat brain hippocampal membranes (Kd = 9.4 nM, Bmax = 213 fmol/mg protein) [2]. in vivo: Chronic treatment with tandospirone, at 0.2 and 1.0mg/kg/day, but not 2.0mg/kg/day, attenuated footshock stress-induced eLAC elevation in the mPFC [3]. Rats were acutely administered tandospirone (0, 0.1, and 1 mg/kg, i.p.). Tandospirone decreased the number of premature responses, an index of impulsive action, in a dose-dependent manner [4]. Toxicity: It is not believed to be addictive but it is known to produce mild withdrawal effects (e.g. anorexia) after abrupt discontinuation.
(4r)-3-{(2s,3s)-2-Hydroxy-3-[(3-Hydroxy-2-Methylbenzoyl)amino]-4-Phenylbutanoyl}-5,5-Dimethyl-N-(2-Methylbenzyl)-1,3-Thiazolidine-4-Carboxamide
Aripiprazole cavoxil
C78272 - Agent Affecting Nervous System > C29710 - Antipsychotic Agent