Exact Mass: 497.2108
Exact Mass Matches: 497.2108
Found 500 metabolites which its exact mass value is equals to given mass value 497.2108
,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Validamycin A
Validamycin A is used in control of fungal infection in rice, potatoes, strawberries and other crops. It is used in control of fungal infection in rice, potatoes, strawberries and other crops Validamycin A, a fungicidal, is an agricultural antibiotic. Validamycin A is originally isolated from Streptomyces hygroscopicus var. limoneus. Validamycin A inhibits the growth of A. flavus, with a MIC of 1?μg/mL[1]. Validamycin A shows potent inhibitory activity against trehalase of Rhizoctonia solani, with an IC50 of 72 μM[2]. Validamycin A is a reversible tyrosinase inhibitor, with a Ki of 5.893 mM[3].
Dexamethasone isonicotinate
N-[[3-[(2S)-2-Hydroxy-3-[[2-[4-[(phenylsulfonyl)amino]phenyl]ethyl]amino]propoxy]phenyl]methyl]-acetamide
6beta-benzoyloxy-3alpha-(E)-(3,4,5-trimethoxycinnamoyloxy)tropane-7beta-ol
6-benzoyloxy-2-(hydroxy-phenyl-methyl)-8-methyl-3-(3-phenyl-acryloyloxy)-nortropane
1,5-Lactan,2,3-di-N-benzyloxycarbonyl,4-tetrahydropyranyl-(2S,3S,4R)-2,3,5-Triamino-4-hydroxypentanoic acid
His Asn Val Glu
His Asn Ile Asp
Ala Phe Phe Asn
Ala Phe Asn Phe
Ala Met Asn Tyr
Ala Met Tyr Asn
Ala Asn Phe Phe
Ala Asn Met Tyr
Ala Asn Tyr Met
Ala Tyr Met Asn
Ala Tyr Asn Met
Cys Phe Lys Thr
Cys Phe Gln Thr
Cys Phe Thr Lys
Cys Phe Thr Gln
Cys Gly Arg Tyr
Cys Gly Tyr Arg
Cys Lys Phe Thr
Cys Lys Thr Phe
Cys Asn Val Tyr
Cys Asn Tyr Val
Cys Gln Phe Thr
Cys Gln Thr Phe
Cys Arg Gly Tyr
Cys Arg Tyr Gly
Cys Thr Phe Lys
Cys Thr Phe Gln
Cys Thr Lys Phe
Cys Thr Gln Phe
Cys Val Asn Tyr
Cys Val Tyr Asn
Cys Tyr Gly Arg
Cys Tyr Asn Val
Cys Tyr Arg Gly
Cys Tyr Val Asn
Asp His Ile Asn
Asp His Leu Asn
Asp His Asn Ile
Asp His Asn Leu
Asp His Gln Val
Asp His Val Gln
Asp Ile His Asn
Asp Ile Asn His
Asp Leu His Asn
Asp Leu Asn His
Asp Asn His Ile
Asp Asn His Leu
Asp Asn Ile His
Asp Asn Leu His
Asp Gln His Val
Asp Gln Val His
Asp Val His Gln
Asp Val Gln His
Glu His Asn Val
Glu His Val Asn
Glu Asn His Val
Glu Asn Val His
Glu Val His Asn
Glu Val Asn His
Phe Ala Phe Asn
Phe Ala Asn Phe
Phe Cys Lys Thr
Phe Cys Gln Thr
Phe Cys Thr Lys
Phe Cys Thr Gln
Phe Phe Ala Asn
Phe Phe Gly Gln
Phe Phe Asn Ala
Phe Phe Gln Gly
Phe Gly Phe Gln
Phe Gly Gln Phe
Phe Lys Cys Thr
Phe Lys Thr Cys
Phe Met Asn Ser
Phe Met Ser Asn
Phe Asn Ala Phe
Phe Asn Phe Ala
Phe Asn Met Ser
Phe Asn Ser Met
Phe Gln Cys Thr
Phe Gln Phe Gly
Phe Gln Gly Phe
Phe Gln Thr Cys
Phe Ser Met Asn
Phe Ser Asn Met
Phe Thr Cys Lys
Phe Thr Cys Gln
Phe Thr Lys Cys
Phe Thr Gln Cys
Gly Cys Arg Tyr
Gly Cys Tyr Arg
Gly Phe Phe Gln
Gly Phe Gln Phe
Gly Lys Met Tyr
Gly Lys Tyr Met
Gly Met Lys Tyr
Gly Met Gln Tyr
Gly Met Tyr Lys
Gly Met Tyr Gln
Gly Gln Phe Phe
Gly Gln Met Tyr
Gly Gln Tyr Met
Gly Arg Cys Tyr
Gly Arg Tyr Cys
Gly Tyr Cys Arg
Gly Tyr Lys Met
Gly Tyr Met Lys
Gly Tyr Met Gln
Gly Tyr Gln Met
Gly Tyr Arg Cys
His Asp Ile Asn
His Asp Leu Asn
His Asp Asn Ile
His Asp Asn Leu
His Asp Gln Val
His Asp Val Gln
His Glu Asn Val
His Glu Val Asn
His Ile Asp Asn
His Ile Asn Asp
His Leu Asp Asn
His Leu Asn Asp
His Met Asn Pro
His Met Pro Asn
His Asn Asp Ile
His Asn Asp Leu
His Asn Glu Val
His Asn Leu Asp
His Asn Met Pro
His Asn Asn Asn
His Asn Pro Met
His Pro Met Asn
His Pro Asn Met
His Gln Asp Val
His Gln Val Asp
His Val Asp Gln
His Val Glu Asn
His Val Asn Glu
His Val Gln Asp
Ile Asp His Asn
Ile Asp Asn His
Ile His Asp Asn
Ile His Asn Asp
Ile Asn Asp His
Ile Asn His Asp
Lys Cys Phe Thr
Lys Cys Thr Phe
Lys Phe Cys Thr
Lys Phe Thr Cys
Lys Gly Met Tyr
Lys Gly Tyr Met
Lys Met Gly Tyr
Lys Met Tyr Gly
Lys Thr Cys Phe
Lys Thr Phe Cys
Lys Tyr Gly Met
Lys Tyr Met Gly
Leu Asp His Asn
Leu Asp Asn His
Leu His Asp Asn
Leu His Asn Asp
Leu Asn Asp His
Leu Asn His Asp
Met Ala Asn Tyr
Met Ala Tyr Asn
Met Phe Asn Ser
Met Phe Ser Asn
Met Gly Lys Tyr
Met Gly Gln Tyr
Met Gly Tyr Lys
Met Gly Tyr Gln
Met His Asn Pro
Met His Pro Asn
Met Asn Ala Tyr
Met Asn Phe Ser
Met Asn His Pro
Met Asn Pro His
Met Asn Ser Phe
Met Asn Tyr Ala
Met Pro His Asn
Met Pro Asn His
Met Gln Gly Tyr
Met Gln Tyr Gly
Met Ser Phe Asn
Met Ser Asn Phe
Met Tyr Ala Asn
Met Tyr Gly Gln
Met Tyr Asn Ala
Met Tyr Gln Gly
Asn Ala Phe Phe
Asn Ala Met Tyr
Asn Ala Tyr Met
Asn Cys Val Tyr
Asn Cys Tyr Val
Asn Asp His Ile
Asn Asp His Leu
Asn Asp Ile His
Asn Asp Leu His
Asn Glu His Val
Asn Glu Val His
Asn Phe Ala Phe
Asn Phe Phe Ala
Asn Phe Met Ser
Asn Phe Ser Met
Asn His Asp Ile
Asn His Asp Leu
Asn His Glu Val
Asn His Ile Asp
Asn His Leu Asp
Asn His Met Pro
Asn His Asn Asn
Asn His Pro Met
Asn His Val Glu
Asn Ile Asp His
Asn Ile His Asp
Asn Leu Asp His
Asn Leu His Asp
Asn Met Ala Tyr
Asn Met Phe Ser
Asn Met His Pro
Asn Met Pro His
Asn Met Ser Phe
Asn Met Tyr Ala
Asn Asn His Asn
Asn Asn Asn His
Asn Pro His Met
Asn Pro Met His
Asn Ser Phe Met
Asn Ser Met Phe
Asn Thr Thr Tyr
Asn Thr Tyr Thr
Asn Val Cys Tyr
Asn Val Glu His
Asn Val His Glu
Asn Val Tyr Cys
Asn Tyr Ala Met
Asn Tyr Cys Val
Asn Tyr Met Ala
Asn Tyr Thr Thr
Asn Tyr Val Cys
Pro His Met Asn
Pro His Asn Met
Pro Met His Asn
Pro Met Asn His
Pro Asn His Met
Pro Asn Met His
Gln Cys Phe Thr
Gln Cys Thr Phe
Gln Asp His Val
Gln Asp Val His
Gln Phe Cys Thr
Gln Phe Phe Gly
Gln Phe Gly Phe
Gln Phe Thr Cys
Gln Gly Phe Phe
Gln Gly Met Tyr
Gln Gly Tyr Met
Gln His Asp Val
Gln His Val Asp
Gln Met Gly Tyr
Gln Met Tyr Gly
Gln Ser Thr Tyr
Gln Ser Tyr Thr
Gln Thr Cys Phe
Gln Thr Phe Cys
Gln Thr Ser Tyr
Gln Thr Tyr Ser
Gln Val Asp His
Gln Val His Asp
Gln Tyr Gly Met
Gln Tyr Met Gly
Gln Tyr Ser Thr
Gln Tyr Thr Ser
Arg Cys Gly Tyr
Arg Cys Tyr Gly
Arg Gly Cys Tyr
Arg Gly Tyr Cys
Arg Tyr Cys Gly
Arg Tyr Gly Cys
Ser Phe Met Asn
Ser Phe Asn Met
Ser Met Phe Asn
Ser Met Asn Phe
Ser Asn Phe Met
Ser Asn Met Phe
Ser Gln Thr Tyr
Ser Gln Tyr Thr
Ser Thr Gln Tyr
Ser Thr Tyr Gln
Ser Tyr Gln Thr
Ser Tyr Thr Gln
Thr Cys Phe Gln
Thr Cys Gln Phe
Thr Phe Cys Gln
Thr Phe Gln Cys
Thr Asn Thr Tyr
Thr Asn Tyr Thr
Thr Gln Cys Phe
Thr Gln Phe Cys
Thr Gln Ser Tyr
Thr Gln Tyr Ser
Thr Ser Gln Tyr
Thr Ser Tyr Gln
Thr Thr Asn Tyr
Thr Thr Tyr Asn
Thr Tyr Asn Thr
Thr Tyr Gln Ser
Thr Tyr Ser Gln
Thr Tyr Thr Asn
Val Cys Asn Tyr
Val Cys Tyr Asn
Val Asp His Gln
Val Asp Gln His
Val Glu His Asn
Val Glu Asn His
Val His Asp Gln
Val His Glu Asn
Val His Asn Glu
Val His Gln Asp
Val Asn Cys Tyr
Val Asn Glu His
Val Asn His Glu
Val Asn Tyr Cys
Val Gln Asp His
Val Gln His Asp
Val Tyr Cys Asn
Val Tyr Asn Cys
Tyr Ala Met Asn
Tyr Ala Asn Met
Tyr Cys Gly Arg
Tyr Cys Asn Val
Tyr Cys Arg Gly
Tyr Cys Val Asn
Tyr Gly Cys Arg
Tyr Gly Met Gln
Tyr Gly Gln Met
Tyr Gly Arg Cys
Tyr Met Ala Asn
Tyr Met Gly Gln
Tyr Met Asn Ala
Tyr Met Gln Gly
Tyr Asn Ala Met
Tyr Asn Cys Val
Tyr Asn Met Ala
Tyr Asn Thr Thr
Tyr Asn Val Cys
Tyr Gln Gly Met
Tyr Gln Met Gly
Tyr Gln Ser Thr
Tyr Gln Thr Ser
Tyr Arg Cys Gly
Tyr Arg Gly Cys
Tyr Ser Gln Thr
Tyr Ser Thr Gln
Tyr Thr Asn Thr
Tyr Thr Gln Ser
Tyr Thr Ser Gln
Tyr Thr Thr Asn
Tyr Val Cys Asn
Tyr Val Asn Cys
dexamethasone isonicotinate
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D005938 - Glucocorticoids C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone C308 - Immunotherapeutic Agent > C574 - Immunosuppressant > C211 - Therapeutic Corticosteroid D000893 - Anti-Inflammatory Agents D018926 - Anti-Allergic Agents
N-2-(4-Benzyloxy-3-methoxyphenethyl)-4-benzyloxy-3-hydroxyphenylacetamide
Dimethylaminomethylfurylmethylthioethyl Ranitidine
Validamycin
Validamycin A, a fungicidal, is an agricultural antibiotic. Validamycin A is originally isolated from Streptomyces hygroscopicus var. limoneus. Validamycin A inhibits the growth of A. flavus, with a MIC of 1?μg/mL[1]. Validamycin A shows potent inhibitory activity against trehalase of Rhizoctonia solani, with an IC50 of 72 μM[2]. Validamycin A is a reversible tyrosinase inhibitor, with a Ki of 5.893 mM[3].
N-(4-fluorophenyl)-2-(3-hydroxypropyl)-5-methyl-7-(3,4,5-trimethoxyphenyl)-1,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide
[(S)-1-[1-(4-Hydroxy-3-methoxy-5-nitro-phenyl)-meth-(E)-ylidene-hydrazinocarbonyl]-2-(1H-indol-3-yl)-ethyl]-carbamic acid isobutyl ester
6-deoxy-alpha-L-mannopyranosyl-(1->3)-2,6-dideoxy-alpha-L-arabino-hexopyranosyl-(1->3)-2-acetamido-2-deoxy-beta-D-glucopyranose
2-(2-methoxyphenyl)-1-oxo-N-[2-oxo-2-[4-(2-pyridinyl)-1-piperazinyl]ethyl]-4-isoquinolinecarboxamide
4-[[4-(1,3-Benzothiazol-2-yl)-1-piperazinyl]-[1-(2-phenylethyl)-5-tetrazolyl]methyl]phenol
N-[(5,8-dimethyl-2-oxo-1H-quinolin-3-yl)methyl]-4-methoxy-N-[3-(2-oxo-1-pyrrolidinyl)propyl]benzenesulfonamide
3-fluoro-N-[[(8S,9S)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-N-methylbenzenesulfonamide
3-fluoro-N-[[(8R,9S)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-9-yl]methyl]-N-methylbenzenesulfonamide
3-fluoro-N-[[(8R,9R)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-N-methylbenzenesulfonamide
(8S,9S)-9-[[(3,4-dichlorophenyl)methyl-methylamino]methyl]-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-5-one
2-fluoro-N-[[(8R,9S)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-9-yl]methyl]-N-methylbenzenesulfonamide
4-fluoro-N-[[(8R,9S)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-9-yl]methyl]-N-methylbenzenesulfonamide
(8R,9R)-9-[[(3,4-dichlorophenyl)methyl-methylamino]methyl]-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-5-one
3-fluoro-N-[[(8R,9R)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-N-methylbenzenesulfonamide
2-fluoro-N-[[(8S,9R)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-9-yl]methyl]-N-methylbenzenesulfonamide
2-fluoro-N-[[(8R,9R)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-N-methylbenzenesulfonamide
2-fluoro-N-[[(8S,9R)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-9-yl]methyl]-N-methylbenzenesulfonamide
4-fluoro-N-[[(8S,9R)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-9-yl]methyl]-N-methylbenzenesulfonamide
4-fluoro-N-[[(8R,9R)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-N-methylbenzenesulfonamide
4-fluoro-N-[[(8R,9S)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-9-yl]methyl]-N-methylbenzenesulfonamide
3-fluoro-N-[[(8S,9S)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-9-yl]methyl]-N-methylbenzenesulfonamide
3-fluoro-N-[[(8R,9R)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-9-yl]methyl]-N-methylbenzenesulfonamide
3-fluoro-N-[[(8S,9R)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-9-yl]methyl]-N-methylbenzenesulfonamide
4-fluoro-N-[[(8R,9R)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-9-yl]methyl]-N-methylbenzenesulfonamide
2-fluoro-N-[[(8R,9R)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-N-methylbenzenesulfonamide
(8R,9R)-9-[[(3,4-dichlorophenyl)methyl-methylamino]methyl]-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-5-one
2-fluoro-N-[[(8S,9S)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-9-yl]methyl]-N-methylbenzenesulfonamide
4-fluoro-N-[[(8S,9R)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-9-yl]methyl]-N-methylbenzenesulfonamide
4-fluoro-N-[[(8S,9S)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-9-yl]methyl]-N-methylbenzenesulfonamide
2-[(1R,3R,4aR,9aS)-6-[[2-(dimethylamino)-1-oxoethyl]amino]-1-(hydroxymethyl)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]-N-(1,3-benzodioxol-5-ylmethyl)acetamide
1-[(1R)-2-(benzenesulfonyl)-1-(hydroxymethyl)-7-methoxy-1-spiro[3,9-dihydro-1H-pyrido[3,4-b]indole-4,4-piperidine]yl]-1-propanone
1-[(1R)-1-(hydroxymethyl)-7-methoxy-2-(4-methylphenyl)sulfonyl-1-spiro[3,9-dihydro-1H-pyrido[3,4-b]indole-4,3-azetidine]yl]-1-butanone
tert-Butyl (3-chloropropyl)((tributylstannyl)methyl)carbamate
4-fluoro-N-[[(8S,9S)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-N-methylbenzenesulfonamide
2-fluoro-N-[[(8S,9S)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-N-methylbenzenesulfonamide
2-fluoro-N-[[(8S,9S)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-N-methylbenzenesulfonamide
(2S,3S,3aR,9bR)-7-(1-cyclohexenyl)-1-[2-(dimethylamino)-1-oxoethyl]-3-(hydroxymethyl)-6-oxo-N-(2-thiazolyl)-3,3a,4,9b-tetrahydro-2H-pyrrolo[2,3-a]indolizine-2-carboxamide
N-[(2R,4aR,12aS)-5-methyl-6-oxo-2-(2-oxo-2-piperidin-1-ylethyl)-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-8-yl]thiophene-2-carboxamide
(8R,9S)-9-[[(3,4-dichlorophenyl)methyl-methylamino]methyl]-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-5-one
(8S,9R)-9-[[(3,4-dichlorophenyl)methyl-methylamino]methyl]-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-5-one
(8S,9S)-9-[[(3,4-dichlorophenyl)methyl-methylamino]methyl]-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-5-one
2-fluoro-N-[[(8S,9R)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-N-methylbenzenesulfonamide
(8R,9S)-9-[[(3,4-dichlorophenyl)methyl-methylamino]methyl]-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-5-one
N-[(2R,4aR,12aR)-5-methyl-6-oxo-2-[2-oxo-2-(1-piperidinyl)ethyl]-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-8-yl]-2-thiophenecarboxamide
(2R,3R,3aS,9bS)-3-(hydroxymethyl)-1-(4-oxazolylmethyl)-6-oxo-N-(phenylmethyl)-7-(3-pyridinyl)-3,3a,4,9b-tetrahydro-2H-pyrrolo[2,3-a]indolizine-2-carboxamide
(8R,9S)-9-[[(3,4-dichlorophenyl)methyl-methylamino]methyl]-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-5-one
(8R,9R)-9-[[(3,4-dichlorophenyl)methyl-methylamino]methyl]-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-5-one
(8R,9R)-9-[[(3,4-dichlorophenyl)methyl-methylamino]methyl]-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-5-one
(8S,9S)-9-[[(3,4-dichlorophenyl)methyl-methylamino]methyl]-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-5-one
2-fluoro-N-[[(8R,9S)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-N-methylbenzenesulfonamide
(8R,9S)-9-[[(3,4-dichlorophenyl)methyl-methylamino]methyl]-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-5-one
(8S,9R)-9-[[(3,4-dichlorophenyl)methyl-methylamino]methyl]-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-5-one
(8S,9R)-9-[[(3,4-dichlorophenyl)methyl-methylamino]methyl]-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-5-one
N-[(2S,4aS,12aR)-5-methyl-6-oxo-2-[2-oxo-2-(1-piperidinyl)ethyl]-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-8-yl]-2-thiophenecarboxamide
N-[(2S,4aS,12aS)-5-methyl-6-oxo-2-[2-oxo-2-(1-piperidinyl)ethyl]-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-8-yl]-2-thiophenecarboxamide
N-[(2S,4aR,12aS)-5-methyl-6-oxo-2-(2-oxo-2-piperidin-1-ylethyl)-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-8-yl]thiophene-2-carboxamide
(2S,3S,3aR,9bR)-N-benzyl-3-(hydroxymethyl)-1-(1,3-oxazol-4-ylmethyl)-6-oxo-7-pyridin-3-yl-3,3a,4,9b-tetrahydro-2H-pyrrolo[2,3-a]indolizine-2-carboxamide
3-fluoro-N-[[(8S,9R)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-N-methylbenzenesulfonamide
4-fluoro-N-[[(8S,9R)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-N-methylbenzenesulfonamide
4-fluoro-N-[[(8R,9S)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-N-methylbenzenesulfonamide
3-fluoro-N-[[(8S,9R)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-N-methylbenzenesulfonamide
4-fluoro-N-[[(8R,9S)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-N-methylbenzenesulfonamide
3-fluoro-N-[[(8R,9S)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-N-methylbenzenesulfonamide
2-fluoro-N-[[(8R,9S)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-N-methylbenzenesulfonamide
4-fluoro-N-[[(8S,9R)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-N-methylbenzenesulfonamide
2-[(1R,3S,4aR,9aS)-6-[[2-(dimethylamino)-1-oxoethyl]amino]-1-(hydroxymethyl)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]-N-(1,3-benzodioxol-5-ylmethyl)acetamide
2-[(1R,3R,4aS,9aR)-6-[[2-(dimethylamino)-1-oxoethyl]amino]-1-(hydroxymethyl)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]-N-(1,3-benzodioxol-5-ylmethyl)acetamide
N-[(2S,4aR,12aR)-5-methyl-6-oxo-2-[2-oxo-2-(1-piperidinyl)ethyl]-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-8-yl]-2-thiophenecarboxamide
(2R,3R,3aS,9bS)-7-(1-cyclohexenyl)-1-[2-(dimethylamino)-1-oxoethyl]-3-(hydroxymethyl)-6-oxo-N-(2-thiazolyl)-3,3a,4,9b-tetrahydro-2H-pyrrolo[2,3-a]indolizine-2-carboxamide
1-[(1R)-2-[(2-chlorophenyl)methyl]-1-(hydroxymethyl)-7-methoxy-1-spiro[3,9-dihydro-1H-pyrido[3,4-b]indole-4,4-piperidine]yl]-2-methoxyethanone
(8S,9R)-9-[[(3,4-dichlorophenyl)methyl-methylamino]methyl]-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-5-one
3-fluoro-N-[[(8R,9S)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-N-methylbenzenesulfonamide
3-fluoro-N-[[(8S,9R)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-9-yl]methyl]-N-methylbenzenesulfonamide
4-fluoro-N-[[(8R,9R)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-N-methylbenzenesulfonamide
2-fluoro-N-[[(8S,9R)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-N-methylbenzenesulfonamide
4-fluoro-N-[[(8S,9S)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-9-yl]methyl]-N-methylbenzenesulfonamide
N-[[(4S,5S)-8-(3-cyanophenyl)-2-[(2R)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^{6},2-benzoxathiazocin-5-yl]methyl]-N-methylcyclopropanecarboxamide
N-[[(4S,5R)-8-(3-cyanophenyl)-2-[(2S)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^{6},2-benzoxathiazocin-5-yl]methyl]-N-methylcyclopropanecarboxamide
2-[(1S,3S,4aS,9aR)-6-[[2-(dimethylamino)-1-oxoethyl]amino]-1-(hydroxymethyl)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]-N-(1,3-benzodioxol-5-ylmethyl)acetamide
2-[(1S,3R,4aS,9aR)-6-[[2-(dimethylamino)-1-oxoethyl]amino]-1-(hydroxymethyl)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]-N-(1,3-benzodioxol-5-ylmethyl)acetamide
2-[(1S,3S,4aR,9aS)-6-[[2-(dimethylamino)-1-oxoethyl]amino]-1-(hydroxymethyl)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]-N-(1,3-benzodioxol-5-ylmethyl)acetamide
2-[(1R,3S,4aS,9aR)-6-[[2-(dimethylamino)-1-oxoethyl]amino]-1-(hydroxymethyl)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]-N-(1,3-benzodioxol-5-ylmethyl)acetamide
2-[(1S,3R,4aR,9aS)-6-[[2-(dimethylamino)-1-oxoethyl]amino]-1-(hydroxymethyl)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]-N-(1,3-benzodioxol-5-ylmethyl)acetamide
N-[(2R,4aS,12aR)-5-methyl-6-oxo-2-[2-oxo-2-(1-piperidinyl)ethyl]-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-8-yl]-2-thiophenecarboxamide
N-[(2R,4aS,12aS)-5-methyl-6-oxo-2-[2-oxo-2-(1-piperidinyl)ethyl]-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-8-yl]-2-thiophenecarboxamide
(1S,9R,10R,11R)-12-acetyl-5-(cyclohexen-1-yl)-N-[(3,5-difluorophenyl)methyl]-10-(hydroxymethyl)-6-oxo-7,12-diazatricyclo[7.2.1.02,7]dodeca-2,4-diene-11-carboxamide
1-[(1S)-1-(hydroxymethyl)-7-methoxy-2-(4-methylphenyl)sulfonyl-1-spiro[3,9-dihydro-1H-pyrido[3,4-b]indole-4,3-azetidine]yl]-1-butanone
1-[(1S)-2-[(2-chlorophenyl)methyl]-1-(hydroxymethyl)-7-methoxy-1-spiro[3,9-dihydro-1H-pyrido[3,4-b]indole-4,4-piperidine]yl]-2-methoxyethanone
1-[(1S)-2-(benzenesulfonyl)-1-(hydroxymethyl)-7-methoxy-1-spiro[3,9-dihydro-1H-pyrido[3,4-b]indole-4,4-piperidine]yl]-1-propanone
5-(Furan-2-yl)-1-(3-imidazol-1-ylpropyl)-4-[4-[(2-methylphenyl)methoxy]benzoyl]pyrrolidine-2,3-dione
Valimon
A member of the class of validamycins that is (1R,2S,3S,4S,6R)-4-amino-6-(hydroxymethyl)cyclohexane-1,2,3-triol in which the hydroxy group at position 1 has been converted to its beta-D-glucoside and in which one of the hydrogens attached to the nitrogen is replaced by a (1R,4R,5R,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl group. It is the major validamycin produced by Streptomyces hygroscopicus. Validamycin A, a fungicidal, is an agricultural antibiotic. Validamycin A is originally isolated from Streptomyces hygroscopicus var. limoneus. Validamycin A inhibits the growth of A. flavus, with a MIC of 1?μg/mL[1]. Validamycin A shows potent inhibitory activity against trehalase of Rhizoctonia solani, with an IC50 of 72 μM[2]. Validamycin A is a reversible tyrosinase inhibitor, with a Ki of 5.893 mM[3].
L748337
L748337 is a potent β3-adrenergic receptor antagonist and displays selectivity over?β1?and?β2?receptors. The Ki values of L748337 for β3-,?β2- and?β1-adrenoceptors are 4.0 nM, 204 nM and 390 nM, respectively[1]. L748337 couples predominantly to Gi to activate MAPK signaling and increases phosphorylation of Erk1/2 with pEC50 value of 11.6[2]. L748337 can be used for the research of cancer, nonalcoholic fatty liver disease (NAFLD), and cardiovascular related diseases[1][2][3].