Exact Mass: 456.0498

Exact Mass Matches: 456.0498

Found 64 metabolites which its exact mass value is equals to given mass value 456.0498, within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error 0.01 dalton.

6-(Dibromomethylene)testosterone

6-(Dibromomethylene)-17beta-hydroxyandrost-4-en-3-one; 6-(Dibromomethylene)testosterone

C20H26Br2O2 (456.0299)

Delnatex

DIOXATHION

C12H26O6P2S4 (456.0087)

Lemildipine

{[4-(2,3-dichlorophenyl)-5-(methoxycarbonyl)-6-methyl-3-[(propan-2-yloxy)carbonyl]-1,4-dihydropyridin-2-yl]methoxy}carboximidic acid

C20H22Cl2N2O6 (456.0855)

C78274 - Agent Affecting Cardiovascular System > C270 - Antihypertensive Agent > C333 - Calcium Channel Blocker D002317 - Cardiovascular Agents > D002121 - Calcium Channel Blockers D000077264 - Calcium-Regulating Hormones and Agents D049990 - Membrane Transport Modulators C93038 - Cation Channel Blocker

Selumetinib

5-[(4-bromo-2-chlorophenyl)amino]-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-1H-1,3-benzodiazole-6-carboximidic acid

C17H15BrClFN4O3 (456)

L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01E - Protein kinase inhibitors > L01EE - Mitogen-activated protein kinase (mek) inhibitors C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C69145 - Mitogen-Activated Protein Kinase Kinase Inhibitor C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor Selumetinib (AZD6244) is selective, non-ATP-competitive oral MEK1/2 inhibitor, with an IC50 of 14 nM for MEK1. Selumetinib (AZD6244) inhibits ERK1/2 phosphorylation.

Benzanilide, 2,2-dithiobis-

2,2-Dibenzoylaminodiphenyl disulfide

C26H20N2O2S2 (456.0966)

CONFIDENCE standard compound; INTERNAL_ID 681; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5297; ORIGINAL_PRECURSOR_SCAN_NO 5295 CONFIDENCE standard compound; INTERNAL_ID 681; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5312; ORIGINAL_PRECURSOR_SCAN_NO 5310 CONFIDENCE standard compound; INTERNAL_ID 681; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5270; ORIGINAL_PRECURSOR_SCAN_NO 5265 CONFIDENCE standard compound; INTERNAL_ID 681; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5309; ORIGINAL_PRECURSOR_SCAN_NO 5307 CONFIDENCE standard compound; INTERNAL_ID 681; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5302; ORIGINAL_PRECURSOR_SCAN_NO 5298 CONFIDENCE standard compound; INTERNAL_ID 681; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5305; ORIGINAL_PRECURSOR_SCAN_NO 5304 CONFIDENCE standard compound; INTERNAL_ID 681; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7946; ORIGINAL_PRECURSOR_SCAN_NO 7945 CONFIDENCE standard compound; INTERNAL_ID 681; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7977; ORIGINAL_PRECURSOR_SCAN_NO 7975 CONFIDENCE standard compound; INTERNAL_ID 681; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7986; ORIGINAL_PRECURSOR_SCAN_NO 7982 CONFIDENCE standard compound; INTERNAL_ID 681; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8027; ORIGINAL_PRECURSOR_SCAN_NO 8025 CONFIDENCE standard compound; INTERNAL_ID 681; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8030; ORIGINAL_PRECURSOR_SCAN_NO 8028

Cys Cys Cys Glu

(2S)-2-[(2R)-2-[(2R)-2-[(2R)-2-amino-3-sulfanylpropanamido]-3-sulfanylpropanamido]-3-sulfanylpropanamido]pentanedioic acid

C14H24N4O7S3 (456.0807)

Cys Cys Glu Cys

(4S)-4-[(2R)-2-[(2R)-2-amino-3-sulfanylpropanamido]-3-sulfanylpropanamido]-4-{[(1R)-1-carboxy-2-sulfanylethyl]carbamoyl}butanoic acid

C14H24N4O7S3 (456.0807)

Cys Glu Cys Cys

(4S)-4-[(2R)-2-amino-3-sulfanylpropanamido]-4-{[(1R)-1-{[(1R)-1-carboxy-2-sulfanylethyl]carbamoyl}-2-sulfanylethyl]carbamoyl}butanoic acid

C14H24N4O7S3 (456.0807)

Glu Cys Cys Cys

(4S)-4-amino-4-{[(1R)-1-{[(1R)-1-{[(1R)-1-carboxy-2-sulfanylethyl]carbamoyl}-2-sulfanylethyl]carbamoyl}-2-sulfanylethyl]carbamoyl}butanoic acid

C14H24N4O7S3 (456.0807)

CAY10561

N-[1-(3-chloro-4-fluorophenyl)-2-hydroxyethyl]-4-[4-(3-chlorophenyl)-1H-pyrazol-3-yl]-1H-pyrrole-2-carboxamide

C22H15Cl2FN4O2 (456.0556)

hexamethonium iodide

C12H30I2N2 (456.0498)

(tert-Butoxycarbonylmethyl)triphenylphosphanium bromide

C24H26BrO2P (456.0854)

3,5-Bis(benzoyl)-1-methanesulfonyloxy-2-deoxy-2,2-difluororibose

C20H18F2O8S (456.069)

Sivelestat Sodium

C20H21N2NaO7S (456.0967)

Ammonium aluminum disulfate dodecahydrate

AlH31NO20S2 (456.0696)

2-Deoxy-2,2-difluoro-D-ribofuranose-3,5-dibenzoate-1-methanesulfonate

C20H18F2O8S (456.069)

Poly(oxy-1,2-ethanediyl), .alpha.-tridecyl-.omega.-hydroxy-, phosphate, potassium salt

C15H32K3O6P (456.0848)

zinc bis(acetato-O)dioxouranate

C4H10O6UZn (456.0277)

Phosphonium,(4-ethoxy-4-oxobutyl)triphenyl-, bromide (1:1)

C24H26BrO2P (456.0854)

2-Deoxy-2,2-difluoro-D-erythro-pentofuranose-3,5-dibenzoate-1-methanesulfonate

C20H18F2O8S (456.069)

(2,4-Dichlorobenzyl)triphenylphosphonium Chloride

C25H20Cl3P (456.0368)

(5-Carboxypentyl) triphenyl phosphonium bromide

C24H26BrO2P (456.0854)

2,6-dichlorobenzyl triphenylphosphonium chloride

C25H20Cl3P (456.0368)

2-(1,3-Dioxan-2-yl)ethyltriphenylphosphonium bromide

C24H26BrO2P (456.0854)

3,3,5,5-tetrakis(trifluoromethyl)benzhydrol

C17H8F12O (456.0384)

Vinyltriethylsilane(hexafluoroacetylacetonate)silver(I)

C13H19AgF6O2Si (456.0109)

2-AMINO-3,6-DICHLOROBENZOICACID

C24H26BrO2P (456.0854)

BIS((1,5-CYCLOOCTADIENE)(HYDROXO)RHODIUM)

C16H26O2Rh2++ (456.0043)

LEAD TRIPHENYL HYDROXIDE

C18H16OPb (456.0967)

Gdc-0623

C16H14FIN4O3 (456.0095)

C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C69145 - Mitogen-Activated Protein Kinase Kinase Inhibitor C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor

Thiamine thiothiazolone pyrophosphate

C12H18N4O7P2S2 (456.0092)

2-benzyl-3-(4-chlorophenyl)-5-(4-nitrophenyl)pyrazolo[1,5-a]pyrimidin-7(4H)-one

C25H17ClN4O3 (456.0989)

5-(3-Morpholin-4-YL-propyl)-2-(3-nitro-phenyl)-4-thioxo-4,5-dihydro-1-thia-3B,5-diaza-cyclopenta[A]pentalen-6-one

C21H20N4O4S2 (456.0926)

Selumetinib

Selumetinib (AZD6244)

C17H15BrClFN4O3 (456)

Lemildipine

C20H22Cl2N2O6 (456.0855)

1-Benzothiophene-3-carboxylic acid 4-[[5-(1-naphthalenyl)-1,3,4-oxadiazol-2-yl]thio]but-2-ynyl ester

C25H16N2O3S2 (456.0602)

N-[4-[[2-(4-hydroxyphenyl)-1,3-dioxo-5-isoindolyl]oxy]phenyl]-2-thiophenecarboxamide

C25H16N2O5S (456.078)

6-[4-Oxo-2-[(4-oxo-2-pyrido[1,2-a]pyrimidinyl)methylthio]-3-thieno[3,2-d]pyrimidinyl]hexanoic acid

C21H20N4O4S2 (456.0926)

3-chloro-N-[3-(furan-2-ylmethylcarbamoyl)-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl]-1-benzothiophene-2-carboxamide

C22H17ClN2O3S2 (456.0369)

7-Methyl-7,8-dihydroguanosine-5-diphosphate(3-)

C11H16N5O11P2-3 (456.0322)

7-Hydroxy-8-[(naphthalen-1-yl)diazenyl]naphthalene-1,3-disulfonate

C20H12N2O7S2-2 (456.0086)

7-Methyl-7,8-dihydroguanosine-5-diphosphate(3-)

C11H16N5O11P2 (456.0322)

An organophosphate oxoanion obtained by deprotonation of the diphosphate OH groups of 7-methyl-7,8-dihydroguanosine-5-diphosphate.

Tinlorafenib

C19H19ClF2N4O3S (456.0834)

Tinlorafenib (PF-07284890) (compound 10) is an orally active BRAF kinase inhibitor, with IC50s of 4.25 and 2.7 nM for BRAFV600E/V600K respectively. Tinlorafenib demonstrates CNS penetration and can be used in the research of BRAF-associated malignant and benign tumors of the CNS as well as extracranial malignancies[1].

UNC9994 (hydrochloride)

C21H23Cl3N2OS (456.0597)

UNC9994 hydrochloride is a functionally selective, β-arrestin–biased dopamine D2 receptor (D2R) agonist that selectively activates β-arrestin recruitment and signaling. UNC9994 hydrochloride shows a binding affinity with a Ki of 79 nM for D2R. UNC9994 hydrochloride is also an antagonist of Gi-regulated cAMP production and partial agonist for D2R/β-arrestin-2 interactions. UNC9994 hydrochloride shows antipsychotic-like activity[1].

(1r,4s,5r,6r,8r,9r,11r,14s,15r,18r,22r)-5,8,22-trihydroxy-19,20,23-trithia-3,13-diazaheptacyclo[13.5.1.1⁶,¹¹.1¹⁴,¹⁸.0¹,¹³.0³,¹¹.0⁴,⁹]tricosane-2,12,16-trione

C18H20N2O6S3 (456.0483)

(1s,4r,5s,6s,8s,9s,11s,14r,15s,18s,22s)-5,8,22-trihydroxy-19,20,23-trithia-3,13-diazaheptacyclo[13.5.1.1⁶,¹¹.1¹⁴,¹⁸.0¹,¹³.0³,¹¹.0⁴,⁹]tricosane-2,12,16-trione

C18H20N2O6S3 (456.0483)

(1r,4s,5r,6s,9r,11r,14s,15r,16s,19r)-5,6,15,16-tetrahydroxy-21,22-dithia-3,13-diazahexacyclo[9.9.2.0¹,¹³.0³,¹¹.0⁴,⁹.0¹⁴,¹⁹]docosane-2,8,12,18-tetrone

C18H20N2O8S2 (456.0661)