Exact Mass: 417.2448
Exact Mass Matches: 417.2448
Found 500 metabolites which its exact mass value is equals to given mass value 417.2448
,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Paspalicine
Cilazapril
C - Cardiovascular system > C09 - Agents acting on the renin-angiotensin system > C09A - Ace inhibitors, plain > C09AA - Ace inhibitors, plain D004791 - Enzyme Inhibitors > D011480 - Protease Inhibitors > D000806 - Angiotensin-Converting Enzyme Inhibitors C78274 - Agent Affecting Cardiovascular System > C270 - Antihypertensive Agent C471 - Enzyme Inhibitor > C783 - Protease Inhibitor > C247 - ACE Inhibitor D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents
Cilazapril
Cilazapril is only found in individuals that have used or taken this drug. It is one of the angiotensin-converting enzyme inhibitors (ACE inhibitors) used for hypertension. It is a prodrug that is hydrolyzed after absorption to its main metabolite cilazaprilat. [PubChem]Cilazapri, as a pyridazine ACE inhibitor, competes with angiotensin I for binding at the angiotensin-converting enzyme, blocking the conversion of angiotensin I to angiotensin II. As angiotensin II is a vasoconstrictor and a negative feedback mediator for renin activity, lower angiotensin II levels results in a decrease in blood pressure, an increase in renin activity, and stimulation of baroreceptor reflex mechanisms. Kininase II, an enzyme which degrades the vasodilator bradykinin, is identical to ACE and may also be inhibited. C - Cardiovascular system > C09 - Agents acting on the renin-angiotensin system > C09A - Ace inhibitors, plain > C09AA - Ace inhibitors, plain D004791 - Enzyme Inhibitors > D011480 - Protease Inhibitors > D000806 - Angiotensin-Converting Enzyme Inhibitors C78274 - Agent Affecting Cardiovascular System > C270 - Antihypertensive Agent C471 - Enzyme Inhibitor > C783 - Protease Inhibitor > C247 - ACE Inhibitor D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents
N-Eicosapentaenoyl Aspartic acid
N-eicosapentaenoyl aspartic acid belongs to the class of compounds known as N-acylamides. These are molecules characterized by a fatty acyl group linked to a primary amine by an amide bond. More specifically, it is an Eicosapentaenoic acid amide of Aspartic acid. It is believed that there are more than 800 types of N-acylamides in the human body. N-acylamides fall into several categories: amino acid conjugates (e.g., those acyl amides conjugated with amino acids), neurotransmitter conjugates (e.g., those acylamides conjugated with neurotransmitters), ethanolamine conjugates (e.g., those acylamides conjugated to ethanolamine), and taurine conjugates (e.g., those acyamides conjugated to taurine). N-Eicosapentaenoyl Aspartic acid is an amino acid conjugate. N-acylamides can be classified into 9 different categories depending on the size of their acyl-group: 1) short-chain N-acylamides; 2) medium-chain N-acylamides; 3) long-chain N-acylamides; and 4) very long-chain N-acylamides; 5) hydroxy N-acylamides; 6) branched chain N-acylamides; 7) unsaturated N-acylamides; 8) dicarboxylic N-acylamides and 9) miscellaneous N-acylamides. N-Eicosapentaenoyl Aspartic acid is therefore classified as a long chain N-acylamide. N-acyl amides have a variety of signaling functions in physiology, including in cardiovascular activity, metabolic homeostasis, memory, cognition, pain, motor control and others (PMID: 15655504). N-acyl amides have also been shown to play a role in cell migration, inflammation and certain pathological conditions such as diabetes, cancer, neurodegenerative disease, and obesity (PMID: 23144998; PMID: 25136293; PMID: 28854168).N-acyl amides can be synthesized both endogenously and by gut microbiota (PMID: 28854168). N-acylamides can be biosynthesized via different routes, depending on the parent amine group. N-acyl ethanolamines (NAEs) are formed via the hydrolysis of an unusual phospholipid precursor, N-acyl-phosphatidylethanolamine (NAPE), by a specific phospholipase D. N-acyl amino acids are synthesized via a circulating peptidase M20 domain containing 1 (PM20D1), which can catalyze the bidirectional the condensation and hydrolysis of a variety of N-acyl amino acids. The degradation of N-acylamides is largely mediated by an enzyme called fatty acid amide hydrolase (FAAH), which catalyzes the hydrolysis of N-acylamides into fatty acids and the biogenic amines. Many N-acylamides are involved in lipid signaling system through interactions with transient receptor potential channels (TRP). TRP channel proteins interact with N-acyl amides such as N-arachidonoyl ethanolamide (Anandamide), N-arachidonoyl dopamine and others in an opportunistic fashion (PMID: 23178153). This signaling system has been shown to play a role in the physiological processes involved in inflammation (PMID: 25136293). Other N-acyl amides, including N-oleoyl-glutamine, have also been characterized as TRP channel antagonists (PMID: 29967167). N-acylamides have also been shown to have G-protein-coupled receptors (GPCRs) binding activity (PMID: 28854168). The study of N-acylamides is an active area of research and it is likely that many novel N-acylamides will be discovered in the coming years. It is also likely that many novel roles in health and disease will be uncovered for these molecules.
Cinepazide
Decoquinate
D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents C254 - Anti-Infective Agent > C258 - Antibiotic > C795 - Quinolone Antibiotic
(Z)-4-(1-{4-[2-(Dimethylamino)ethoxy]phenyl}-5-hydroxy-2-phenylpent-1-enyl)phenol
DECOQUINATE
D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents C254 - Anti-Infective Agent > C258 - Antibiotic > C795 - Quinolone Antibiotic CONFIDENCE standard compound; INTERNAL_ID 1087
5,6-dihydroxy-9,12,13-trimethyl-14-(2-methylpropyl)-2H,5H,6H,7H,8H,13H,13aH,14H,15H,16H,16bH-oxacyclododeca[3,2-e]isoindole-2,16-dione
1H-Cycloundec[d]isoindole-1,12,15-trione, 2,3,3a,4,6a,9,10,11,13,14-decahydro-11,13-dihydroxy-4,5,8-trimethyl-3-(2-methylpropyl)-, (7E)-
hydroxydaphgraciline|methyl (4S,6R,6?S,10aR,11S)-6?-ethyl-2,3,4,5,5?,6,6?,7,8,10-decahydro-6-hydroxy-6?-methoxy-2-methyl-1H,4?H-spiro[4,10a-methanopentaleno[1,6-cd]azonine-11,3?-pyran]-9-carboxylate
(3R,8S,Z)-3-hydroxyheptadeca-1,9-dien-4,6-diyn-8-yl 11-(1H-indol-3-yl)acetate
Ile Ala Ser Lys
Ala Glu Lys Ala
Thr Val Ala Lys
C24H35NO5_(1aS,2R,3R,6E,10S,10aR,11S,13aS,14aS)-2,3-Dihydroxy-11-isobutyl-6,9,10-trimethyl-3,4,5,7a,10,10a,11,12-octahydro-1aH-oxireno[9,10]cycloundeca[1,2-d]isoindole-13,14(2H,14aH)-dione
5,6-dihydroxy-9,12,13-trimethyl-14-(2-methylpropyl)-2H,5H,6H,7H,8H,13H,13aH,14H,15H,16H,16bH-oxacyclododeca[3,2-e]isoindole-2,16-dione_major
Ala Ala Glu Lys
Ala Ala Lys Glu
Ala Ala Arg Thr
Ala Ala Thr Arg
Ala Glu Ala Lys
Ala Ile Lys Ser
Ala Ile Asn Thr
Ala Ile Gln Ser
Ala Ile Ser Lys
Ala Ile Ser Gln
Ala Ile Thr Asn
Ala Lys Ala Glu
Ala Lys Glu Ala
Ala Lys Ile Ser
Ala Lys Leu Ser
Ala Lys Ser Ile
Ala Lys Ser Leu
Ala Lys Thr Val
Ala Lys Val Thr
Ala Leu Lys Ser
Ala Leu Asn Thr
Ala Leu Gln Ser
Ala Leu Ser Lys
Ala Leu Ser Gln
Ala Leu Thr Asn
Ala Asn Ile Thr
Ala Asn Leu Thr
Ala Asn Thr Ile
Ala Asn Thr Leu
Ala Gln Ile Ser
Ala Gln Leu Ser
Ala Gln Ser Ile
Ala Gln Ser Leu
Ala Gln Thr Val
Ala Gln Val Thr
Ala Arg Ala Thr
Ala Arg Thr Ala
Ala Ser Ile Lys
Ala Ser Ile Gln
Ala Ser Lys Ile
Ala Ser Lys Leu
Ala Ser Leu Lys
Ala Ser Leu Gln
Ala Ser Gln Ile
Ala Ser Gln Leu
Ala Thr Ala Arg
Ala Thr Ile Asn
Ala Thr Lys Val
Ala Thr Leu Asn
Ala Thr Asn Ile
Ala Thr Asn Leu
Ala Thr Gln Val
Ala Thr Arg Ala
Ala Thr Val Lys
Ala Thr Val Gln
Ala Val Lys Thr
Ala Val Gln Thr
Ala Val Thr Lys
Ala Val Thr Gln
Asp Gly Lys Val
Asp Gly Val Lys
Asp Lys Gly Val
Asp Lys Val Gly
Asp Val Gly Lys
Asp Val Lys Gly
Glu Ala Ala Lys
Glu Ala Lys Ala
Glu Lys Ala Ala
Gly Asp Lys Val
Gly Asp Val Lys
Gly Ile Lys Thr
Gly Ile Gln Thr
Gly Ile Thr Lys
Gly Ile Thr Gln
Gly Lys Asp Val
Gly Lys Ile Thr
Gly Lys Leu Thr
Gly Lys Thr Ile
Gly Lys Thr Leu
Gly Lys Val Asp
Gly Leu Lys Thr
Gly Leu Gln Thr
Gly Leu Thr Lys
Gly Leu Thr Gln
Gly Gln Ile Thr
Gly Gln Leu Thr
Gly Gln Thr Ile
Gly Gln Thr Leu
Gly Arg Ser Val
Gly Arg Val Ser
Gly Ser Arg Val
Gly Ser Val Arg
Gly Thr Ile Lys
Gly Thr Ile Gln
Gly Thr Lys Ile
Gly Thr Lys Leu
Gly Thr Leu Lys
Gly Thr Leu Gln
Gly Thr Gln Ile
Gly Thr Gln Leu
Gly Val Asp Lys
Gly Val Lys Asp
Gly Val Arg Ser
Gly Val Ser Arg
Ile Ala Lys Ser
Ile Ala Asn Thr
Ile Ala Gln Ser
Ile Ala Ser Gln
Ile Ala Thr Asn
Ile Gly Lys Thr
Ile Gly Gln Thr
Ile Gly Thr Lys
Ile Gly Thr Gln
Ile Lys Ala Ser
Ile Lys Gly Thr
Ile Lys Ser Ala
Ile Lys Thr Gly
Ile Asn Ala Thr
Ile Asn Thr Ala
Ile Gln Ala Ser
Ile Gln Gly Thr
Ile Gln Ser Ala
Ile Gln Thr Gly
Ile Ser Ala Lys
Ile Ser Ala Gln
Ile Ser Lys Ala
Ile Ser Gln Ala
Ile Thr Ala Asn
Ile Thr Gly Lys
Ile Thr Gly Gln
Ile Thr Lys Gly
Ile Thr Asn Ala
Ile Thr Gln Gly
Lys Ala Ala Glu
Lys Ala Glu Ala
Lys Ala Ile Ser
Lys Ala Leu Ser
Lys Ala Ser Ile
Lys Ala Ser Leu
Lys Ala Thr Val
Lys Ala Val Thr
Lys Asp Gly Val
Lys Asp Val Gly
Lys Glu Ala Ala
Lys Gly Asp Val
Lys Gly Ile Thr
Lys Gly Leu Thr
Lys Gly Thr Ile
Lys Gly Thr Leu
Lys Gly Val Asp
Lys Ile Ala Ser
Lys Ile Gly Thr
Lys Ile Ser Ala
Lys Ile Thr Gly
Lys Leu Ala Ser
Lys Leu Gly Thr
Lys Leu Ser Ala
Lys Leu Thr Gly
Lys Pro Ser Ser
Lys Ser Ala Ile
Lys Ser Ala Leu
Lys Ser Ile Ala
Lys Ser Leu Ala
Lys Ser Pro Ser
Lys Ser Ser Pro
Lys Thr Ala Val
Lys Thr Gly Ile
Lys Thr Gly Leu
Lys Thr Ile Gly
Lys Thr Leu Gly
Lys Thr Val Ala
Lys Val Ala Thr
Lys Val Asp Gly
Lys Val Gly Asp
Lys Val Thr Ala
Leu Ala Lys Ser
Leu Ala Asn Thr
Leu Ala Gln Ser
Leu Ala Ser Lys
Leu Ala Ser Gln
Leu Ala Thr Asn
Leu Gly Lys Thr
Leu Gly Gln Thr
Leu Gly Thr Lys
Leu Gly Thr Gln
Leu Lys Ala Ser
Leu Lys Gly Thr
Leu Lys Ser Ala
Leu Lys Thr Gly
Leu Asn Ala Thr
Leu Asn Thr Ala
Leu Gln Ala Ser
Leu Gln Gly Thr
Leu Gln Ser Ala
Leu Gln Thr Gly
Leu Ser Ala Lys
Leu Ser Ala Gln
Leu Ser Lys Ala
Leu Ser Gln Ala
Leu Thr Ala Asn
Leu Thr Gly Lys
Leu Thr Gly Gln
Leu Thr Lys Gly
Leu Thr Asn Ala
Leu Thr Gln Gly
Asn Ala Ile Thr
Asn Ala Leu Thr
Asn Ala Thr Ile
Asn Ala Thr Leu
Asn Ile Ala Thr
Asn Ile Thr Ala
Asn Leu Ala Thr
Asn Leu Thr Ala
Arg Ala Ala Thr
Arg Ala Thr Ala
Arg Gly Ser Val
Arg Gly Val Ser
Arg Ser Gly Val
Arg Ser Val Gly
Arg Thr Ala Ala
Arg Val Gly Ser
Arg Val Ser Gly
Ser Ala Ile Lys
Ser Ala Lys Ile
Ser Ala Lys Leu
Ser Ala Leu Lys
Ser Gly Arg Val
Ser Gly Val Arg
Ser Ile Ala Lys
Ser Ile Lys Ala
Ser Lys Ala Ile
Ser Lys Ala Leu
Ser Lys Ile Ala
Ser Lys Leu Ala
Ser Leu Ala Lys
Ser Leu Lys Ala
Ser Arg Gly Val
Ser Arg Val Gly
Ser Val Gly Arg
Ser Val Arg Gly
Thr Ala Ala Arg
Thr Ala Lys Val
Thr Ala Arg Ala
Thr Ala Val Lys
Thr Gly Ile Lys
Thr Gly Lys Ile
Thr Gly Lys Leu
Thr Gly Leu Lys
Thr Ile Gly Lys
Thr Ile Lys Gly
Thr Lys Ala Val
Thr Lys Gly Ile
Thr Lys Gly Leu
Thr Lys Ile Gly
Thr Lys Leu Gly
Thr Lys Val Ala
Thr Leu Gly Lys
Thr Leu Lys Gly
Thr Arg Ala Ala
Thr Val Lys Ala
Val Ala Lys Thr
Val Ala Thr Lys
Val Gly Arg Ser
Val Gly Ser Arg
Val Lys Ala Thr
Val Lys Thr Ala
Val Arg Gly Ser
Val Arg Ser Gly
Val Ser Gly Arg
Val Ser Arg Gly
Val Thr Ala Lys
Val Thr Lys Ala
(3E,9E)-5,6-dihydroxy-14-isobutyl-9,12,13-trimethyl-6,7,8,10a,13,13a,14,15-octahydro-2H-[1]oxacyclododecino[2,3-d]isoindole-2,16(5H)-dione
N-Cyclohexyl-4-[3-phenyl-5-(1-piperidinylmethyl)-1,2-oxazol-4-yl] -2-pyrimidinamine
(R)-8-FLUORO-N-ISOPROPYL-4-(3-METHOXYPROPOXY)-6-METHYL-N-(PIPERIDIN-3-YL)QUINOLINE-2-CARBOXAMIDE
4-(4-tert-Butoxycarbonylamino-cyclohexyl)-piperazine-1-carboxylic acid benzyl ester
Cinepazide
C - Cardiovascular system > C04 - Peripheral vasodilators > C04A - Peripheral vasodilators C78274 - Agent Affecting Cardiovascular System > C29707 - Vasodilating Agent D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents
bis(2-hydroxyethyl)[2-hydroxy-3-(octyloxy)propyl]methylammonium methyl sulphate
(R)-α,α-Bis(3,5-dimethylphenyl)-2-pyrrolidineMethanol triMethylsilyl ether hydrochloride 97
N,N-Dimethyl-2-[[(1R,2R,4R)-1,7,7-trimethyl-2-phenylbicyclo[2.2.1]hept-2-yl]oxy]ethanamine (2E)-2-butenedioate
(Z)-4-(1-{4-[2-(Dimethylamino)ethoxy]phenyl}-5-hydroxy-2-phenylpent-1-enyl)phenol
2-Naphthalenecarboxamide, N-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)-
D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents > D018491 - Dopamine Agonists
(R)-2-((9-Isopropyl-6-((3-(pyridin-2-yl)phenyl)amino)-9H-purin-2-yl)amino)butan-1-ol
3,3-Dipentyloxacarbocyanine
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D049408 - Luminescent Agents D004396 - Coloring Agents > D005456 - Fluorescent Dyes D004396 - Coloring Agents > D002232 - Carbocyanines
(9E)-4,6-Dihydroxy-9,13,14-trimethyl-16-(2-methylpropyl)-17-azatricyclo[9.7.0.01,15]octadeca-9,12-diene-2,5,18-trione
6-Ethyl-5-[(2s)-1-(3-Methoxypropyl)-2-Phenyl-1,2,3,4-Tetrahydroquinolin-7-Yl]pyrimidine-2,4-Diamine
6-Hydroxy-10,14,15-trimethyl-17-(2-methylpropyl)-2-oxa-18-azatricyclo[10.7.0.01,16]nonadeca-10,13-diene-3,7,19-trione
8-Acetoxyheterophyllisine
A diterpene alkaloid isolated from the roots of Delphinium denudatum that exhibits antifungal activity.