Exact Mass: 395.0875
Exact Mass Matches: 395.0875
Found 164 metabolites which its exact mass value is equals to given mass value 395.0875,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Gonyautoxin II
{4-[(carbamoyloxy)methyl]-10,10-dihydroxy-2,6-diimino-hexahydro-1H-pyrrolo[1,2-c]purin-9-yl}oxidanesulfonic acid
Gonyautoxin III is found in mollusks. Gonyautoxin III is from Gonyaulax and Protogonyaulax species. From Gonyaulax and Protogonyaulax subspecies Gonyautoxin II is found in mollusks. D009676 - Noxae > D011042 - Poisons > D008978 - Mollusk Venoms D009676 - Noxae > D011042 - Poisons > D008387 - Marine Toxins D009676 - Noxae > D011042 - Poisons > D014688 - Venoms
Toxin b2
Gonyautoxin 6; Gonyautoxin VI; GTX6; Toxin B2
D009676 - Noxae > D011042 - Poisons > D008978 - Mollusk Venoms D009676 - Noxae > D011042 - Poisons > D008387 - Marine Toxins D009676 - Noxae > D011042 - Poisons > D014688 - Venoms
Gonyautoxin VI
N-SulphO({5,10,10-trihydroxy-2,6-diimino-decahydropyrrolo[1,2-c]purin-4-yl}methoxy)carboximidic acid
Gonyautoxin VI is found in mollusks. Gonyautoxin VI is produced by Gonyaulax and Protogonyaulax species, isolated from shellfish. Neurotoxin; causal agent with Saxitoxin, of shellfish poisoning. Production by Gonyaulax and Protogonyaulax subspecies, isolated from shellfish. Neurotoxin; causal agent with Saxitoxin, of shellfish poisoning. Gonyautoxin VI is found in mollusks.
Oxaliplatin
(3aR,7aR)-octahydro-2,5-dioxaspiro[cyclohexa[d]1,3-diaza-2-platinacyclopentane-2,1-cyclopentane]-3,4-dione
Oxaliplatin is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin. It is typically administered in combination with fluorouracil and leucovorin in a combination known as Folfox for the treatment of colorectal cancer. Compared to cisplatin the two amine groups are replaced by cyclohexyldiamine for improved antitumour activity. The chlorine ligands are replaced by the oxalato bidentate derived from oxalic acid in order to improve water solubility. Oxaliplatin is marketed by Sanofi-Aventis under the trademark Eloxatin®.
2,5-Dimethylcelecoxib
4-[5-(2,5-dimethylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide
Balaglitazone
5-({4-[(3-methyl-4-oxo-3,4-dihydroquinazolin-2-yl)methoxy]phenyl}methyl)-1,3-thiazolidine-2,4-dione
C78276 - Agent Affecting Digestive System or Metabolism > C29711 - Anti-diabetic Agent > C98241 - Thiazolidinedione Antidiabetic Agent Balaglitazone is a selective partial PPARγ agonist with an EC50 of 1.351 μM for human PPARγ.
5-Pyrimidinecarboxylic acid, 4-(2-chloro-4-fluorophenyl)-2-(3,5-difluoro-2-pyridinyl)-1,4-dihydro-6-methyl-, methyl ester, (4R)-
5-Pyrimidinecarboxylic acid, 4-(2-chloro-4-fluorophenyl)-2-(3,5-difluoro-2-pyridinyl)-1,4-dihydro-6-methyl-, methyl ester, (4R)-
Guanidine, N-(4-chlorophenyl)-N'-cyano-N'-(6-cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl)-, trans-
Guanidine, N-(4-chlorophenyl)-N-cyano-N-(6-cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl)-, trans-
Imidodicarbonimidic diamide, N-(1-methylethyl)-N'-(3-(2,4,5-trichlorophenoxy)propoxy)-, hydrochloride
1-{[amino({[3-(2,4,5-trichlorophenoxy)propoxy]amino})methylidene]amino}-N-(propan-2-yl)methanimidamide
M1
N-SulphO({9,10,10-trihydroxy-2,6-diimino-decahydropyrrolo[1,2-c]purin-4-yl}methoxy)carboximidic acid
Basic protein, MW 5677 Da. A gamma-thionin showing antifungal activity. Isolated from seeds of yellow mustard, Sinapis alba. [CCD]. M1 is found in brassicas.
Benzomalvin C
(2S,3S)-6-Methyl-3-phenyl-13H-spiro[oxirane-2,7-quinazolino[3,2-a][1,4]benzodiazepine]-5,13(6H)-dione
7-hydroxy-1-(1-hydroxyethyl)-8-methyl-2,3,8,9a,10,12a-hexahydro-6H-benzo[cd]furo[2,3:5,6]pyrano[3,4-g]pyrrolo[1,2-a]indole-6,11(1H)-dione
7-hydroxy-1-(1-hydroxyethyl)-8-methyl-2,3,8,9a,10,12a-hexahydro-6H-benzo[cd]furo[2,3:5,6]pyrano[3,4-g]pyrrolo[1,2-a]indole-6,11(1H)-dione
spiro[(5S)-3-methoxy-2-cyclopenten-1-one-5:3(2S)-2-chloro-3aS,7aS-((2,3)-1-methylpyrrolidine)-6,7-dimethoxy-1,2,3,3a,4,7a-hexahydro-4H,5H-inden-4,5-dione]
spiro[(5S)-3-methoxy-2-cyclopenten-1-one-5:3(2S)-2-chloro-3aS,7aS-((2,3)-1-methylpyrrolidine)-6,7-dimethoxy-1,2,3,3a,4,7a-hexahydro-4H,5H-inden-4,5-dione]
2-(4-hydroxybenzoyloxymethyl)-4-O-beta-D-glucopyranosyloxy-2(E)-butenenitrile|nigrumin-4-hydroxy-benzoate
2-(4-hydroxybenzoyloxymethyl)-4-O-beta-D-glucopyranosyloxy-2(E)-butenenitrile|nigrumin-4-hydroxy-benzoate
4,9,10,11-tetramethoxy-benzo[g][1,3]dioxolo[4,5:4,5]benzo[1,2,3-de]quinolin-8-one|Ocominaron|Ocominarone
4,9,10,11-tetramethoxy-benzo[g][1,3]dioxolo[4,5:4,5]benzo[1,2,3-de]quinolin-8-one|Ocominaron|Ocominarone
5-[(6,7-Dimethoxyisoquinolin-1-yl)carbonyl]-1,3-benzodioxole-4-carboxylic acid methyl ester
5-[(6,7-Dimethoxyisoquinolin-1-yl)carbonyl]-1,3-benzodioxole-4-carboxylic acid methyl ester
3-Methyl-3-(6,7-dimethoxyisoquinoline-1-yl)-4,7-dimethoxyisobenzofuran-1(3H)-one
3-Methyl-3-(6,7-dimethoxyisoquinoline-1-yl)-4,7-dimethoxyisobenzofuran-1(3H)-one
cardiospermin-5-(4-hydroxy) benzoate|Cardiospermin-5-(4-hydroxy)benzoate
cardiospermin-5-(4-hydroxy) benzoate|Cardiospermin-5-(4-hydroxy)benzoate
3-(6,7-Dimethoxy-isoquinolin-1-yl)-3-(3,4-dimethoxy-phenyl)-acrylic acid
"NCGC00160257-01!3-(6,7-Dimethoxy-isoquinolin-1-yl)-3-(3,4-dimethoxy-phenyl)-acrylic acid"
C24H17N3O3_Spiro[oxirane-2,7(13H)-quinazolino[3,2-a][1,4]benzodiazepine]-5,13(6H)-dione, 6-methyl-3-phenyl-, (2S,3S)
NCGC00180312-03_C24H17N3O3_Spiro[oxirane-2,7(13H)-quinazolino[3,2-a][1,4]benzodiazepine]-5,13(6H)-dione, 6-methyl-3-phenyl-, (2S,3S)-
(2S,3S)-6-methyl-3-phenylspiro[oxirane-2,7-quinazolino[3,2-a][1,4]benzodiazepine]-5,13-dione
(2S,3S)-6-methyl-3-phenylspiro[oxirane-2,7-quinazolino[3,2-a][1,4]benzodiazepine]-5,13-dione
Cys Cys Gly Asn
(2S)-2-{2-[(2R)-2-[(2R)-2-amino-3-sulfanylpropanamido]-3-sulfanylpropanamido]acetamido}-3-carbamoylpropanoic acid
Cys Cys Asn Gly
2-[(2S)-2-[(2R)-2-[(2R)-2-amino-3-sulfanylpropanamido]-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetic acid
Cys Gly Cys Asn
(2S)-2-[(2R)-2-{2-[(2R)-2-amino-3-sulfanylpropanamido]acetamido}-3-sulfanylpropanamido]-3-carbamoylpropanoic acid
Cys Gly Asn Cys
(2R)-2-[(2S)-2-{2-[(2R)-2-amino-3-sulfanylpropanamido]acetamido}-3-carbamoylpropanamido]-3-sulfanylpropanoic acid
Cys Asn Cys Gly
2-[(2R)-2-[(2S)-2-[(2R)-2-amino-3-sulfanylpropanamido]-3-carbamoylpropanamido]-3-sulfanylpropanamido]acetic acid
Cys Asn Gly Cys
(2R)-2-{2-[(2S)-2-[(2R)-2-amino-3-sulfanylpropanamido]-3-carbamoylpropanamido]acetamido}-3-sulfanylpropanoic acid
Gly Cys Cys Asn
(2S)-2-[(2R)-2-[(2R)-2-(2-aminoacetamido)-3-sulfanylpropanamido]-3-sulfanylpropanamido]-3-carbamoylpropanoic acid
Gly Cys Asn Cys
(2R)-2-[(2S)-2-[(2R)-2-(2-aminoacetamido)-3-sulfanylpropanamido]-3-carbamoylpropanamido]-3-sulfanylpropanoic acid
Gly Asn Cys Cys
(2R)-2-[(2R)-2-[(2S)-2-(2-aminoacetamido)-3-carbamoylpropanamido]-3-sulfanylpropanamido]-3-sulfanylpropanoic acid
Asn Cys Cys Gly
2-[(2R)-2-[(2R)-2-[(2S)-2-amino-3-carbamoylpropanamido]-3-sulfanylpropanamido]-3-sulfanylpropanamido]acetic acid
Asn Cys Gly Cys
(2R)-2-{2-[(2R)-2-[(2S)-2-amino-3-carbamoylpropanamido]-3-sulfanylpropanamido]acetamido}-3-sulfanylpropanoic acid
Asn Gly Cys Cys
(2R)-2-[(2R)-2-{2-[(2S)-2-amino-3-carbamoylpropanamido]acetamido}-3-sulfanylpropanamido]-3-sulfanylpropanoic acid
N-(4,7-Dihydroxy-8-methyl-2-oxo-2H-chromen-3-yl)-2,2-dimethylchromane-6-carboxamide
N-(4,7-Dihydroxy-8-methyl-2-oxo-2H-chromen-3-yl)-2,2-dimethylchromane-6-carboxamide
[4-(2,4-difluorophenyl)-2-[(2,5-dimethylphenyl)carbamoyl]phenyl] acetate
[4-(2,4-difluorophenyl)-2-[(2,5-dimethylphenyl)carbamoyl]phenyl] acetate
6-(3-chloropropoxy)-N- (3-chloro-4-fluorophenyl)-7-Methoxyquinazolin-4-aMine
6-(3-chloropropoxy)-N- (3-chloro-4-fluorophenyl)-7-Methoxyquinazolin-4-aMine
tert-butyl 7-bromo-4-oxospiro[3H-chromene-2,4-piperidine]-1-carboxylate
tert-butyl 7-bromo-4-oxospiro[3H-chromene-2,4-piperidine]-1-carboxylate
3-(4-chlorophenyl)sulfanyl-4-ethylsulfonyl-7-methoxy-2-methyl-1H-indole
3-(4-chlorophenyl)sulfanyl-4-ethylsulfonyl-7-methoxy-2-methyl-1H-indole
tert-Butyl ((diphenylphosphoryl)methyl)sulfonylcarbamate
tert-Butyl ((diphenylphosphoryl)methyl)sulfonylcarbamate
tert-Butyl 6-bromo-4-oxospiro[chroman-2,4-piperidine]-1-carboxylate
tert-Butyl 6-bromo-4-oxospiro[chroman-2,4-piperidine]-1-carboxylate
(R)-2-(((BENZYLOXY)CARBONYL)AMINO)BUTANE-1,4-DIYL DIMETHANESULFONATE
(R)-2-(((BENZYLOXY)CARBONYL)AMINO)BUTANE-1,4-DIYL DIMETHANESULFONATE
2-AMINO-5,7-DIPHENYL-4,7-DIHYDRO-5H-THIENO[2,3-C]THIOPYRAN-3-CARBOXYLIC ACID EHYL ESTER
2-AMINO-5,7-DIPHENYL-4,7-DIHYDRO-5H-THIENO[2,3-C]THIOPYRAN-3-CARBOXYLIC ACID EHYL ESTER
[4-(2,4-difluorophenyl)-2-(propylcarbamoyl)phenyl] benzoate
[4-(2,4-difluorophenyl)-2-(propylcarbamoyl)phenyl] benzoate
4-Benzyloxy-2-(2carbomethoxy)thiophenylnitrobenzene
4-Benzyloxy-2-(2carbomethoxy)thiophenylnitrobenzene
(2R,3R,4S,5R)-2-(6-amino-2-(3,3,3-trifluoropropylthio)-9H-purin-9-yl)-5-(hydroxyMethyl)tetrahydrofuran-3,4-diol
(2R,3R,4S,5R)-2-(6-amino-2-(3,3,3-trifluoropropylthio)-9H-purin-9-yl)-5-(hydroxyMethyl)tetrahydrofuran-3,4-diol
5-[3-(TERT-BUTYL)-1-(2,4-DICHLOROBENZYL)-1H-PYRAZOL-5-YL]-4-METHYL-4H-1,2,4-TRIAZOLE-3-THIOL
5-[3-(TERT-BUTYL)-1-(2,4-DICHLOROBENZYL)-1H-PYRAZOL-5-YL]-4-METHYL-4H-1,2,4-TRIAZOLE-3-THIOL
1-tert-Butyl 4-(pentafluorophenyl) piperidine-1,4-dicarboxylate
1-tert-Butyl 4-(pentafluorophenyl) piperidine-1,4-dicarboxylate
Imidodicarbonimidic diamide, N-(1-methylethyl)-N-(3-(2,4,5-trichlorophenoxy)propoxy)-, hydrochloride
Imidodicarbonimidic diamide, N-(1-methylethyl)-N-(3-(2,4,5-trichlorophenoxy)propoxy)-, hydrochloride
D007004 - Hypoglycemic Agents > D001645 - Biguanides
methyl 5-[(E)-(tert-butylcarbamothioylhydrazinylidene)methyl]-1-(2,4-difluorophenyl)pyrazole-4-carboxylate
methyl 5-[(E)-(tert-butylcarbamothioylhydrazinylidene)methyl]-1-(2,4-difluorophenyl)pyrazole-4-carboxylate
(E)-2-Benzylidene-5-bromo-3-(cyclohexylamino)-2,3-dihydro-1H-inden-1-one
(E)-2-Benzylidene-5-bromo-3-(cyclohexylamino)-2,3-dihydro-1H-inden-1-one
2-(6-{[(3-Chloro-2-Methylphenyl)sulfonyl]amino}pyridin-2-Yl)-N,N-Diethylacetamide
2-(6-{[(3-Chloro-2-Methylphenyl)sulfonyl]amino}pyridin-2-Yl)-N,N-Diethylacetamide
(2r,3r)-7-(Methylsulfonyl)-3-(2,4,5-Trifluorophenyl)-1,2,3,4-Tetrahydropyrido[1,2-A]benzimidazol-2-Amine
(2r,3r)-7-(Methylsulfonyl)-3-(2,4,5-Trifluorophenyl)-1,2,3,4-Tetrahydropyrido[1,2-A]benzimidazol-2-Amine
1-[(1S)-Carboxy-2-(methylsulfinyl)ethyl]-(3R)-[(5S)-5-amino-5-carboxypentanamido]-(4R)-sulfanylazetidin-2-one
1-[(1S)-Carboxy-2-(methylsulfinyl)ethyl]-(3R)-[(5S)-5-amino-5-carboxypentanamido]-(4R)-sulfanylazetidin-2-one
(2,6-diamino-9,10,10-trihydroxy-3a,4,8,9-tetrahydro-1H-pyrrolo[1,2-c]purin-4-yl)methoxycarbonylsulfamic acid
(2,6-diamino-9,10,10-trihydroxy-3a,4,8,9-tetrahydro-1H-pyrrolo[1,2-c]purin-4-yl)methoxycarbonylsulfamic acid
Guanidine, N-(4-chlorophenyl)-N'-cyano-N'-(6-cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl)-, trans-
Guanidine, N-(4-chlorophenyl)-N-cyano-N-(6-cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl)-, trans-
Gonyautoxin 2
Gonyautoxin 2
D009676 - Noxae > D011042 - Poisons > D008978 - Mollusk Venoms D009676 - Noxae > D011042 - Poisons > D008387 - Marine Toxins D009676 - Noxae > D011042 - Poisons > D014688 - Venoms
Nogalaviketone(1-)
Nogalaviketone(1-)
A phenolate anion obtained by deprotonation of the 5-OH group of nogalaviketone. It is the major microspecies at pH 7.3 (according to Marvin v 6.2.0.).
4-[3-(3-Fluorophenyl)-5-phenyl-3,4-dihydropyrazol-2-yl]benzenesulfonamide
4-[3-(3-Fluorophenyl)-5-phenyl-3,4-dihydropyrazol-2-yl]benzenesulfonamide
6-Amino-1,3-dimethyl-5-[(3-methyl-1-phenyl-5-thieno[2,3-c]pyrazolyl)-oxomethyl]pyrimidine-2,4-dione
6-Amino-1,3-dimethyl-5-[(3-methyl-1-phenyl-5-thieno[2,3-c]pyrazolyl)-oxomethyl]pyrimidine-2,4-dione
2-(3-Chlorophenoxy)acetic acid [4-[(4-methylanilino)-oxomethyl]phenyl] ester
2-(3-Chlorophenoxy)acetic acid [4-[(4-methylanilino)-oxomethyl]phenyl] ester
5-[(2-Fluorophenyl)methyl]-6,11-dioxo-3-benzo[b][1,4]benzothiazepinecarboxylic acid
5-[(2-Fluorophenyl)methyl]-6,11-dioxo-3-benzo[b][1,4]benzothiazepinecarboxylic acid
4-(2,4-Dichlorophenoxy)butanoic acid [2-oxo-2-[(phenylmethyl)amino]ethyl] ester
4-(2,4-Dichlorophenoxy)butanoic acid [2-oxo-2-[(phenylmethyl)amino]ethyl] ester
N-[4-[(4-sulfamoylphenyl)sulfamoyl]phenyl]cyclopropanecarboxamide
N-[4-[(4-sulfamoylphenyl)sulfamoyl]phenyl]cyclopropanecarboxamide
1-[4-Chloro-3-(4-morpholinylsulfonyl)phenyl]-3-phenylurea
1-[4-Chloro-3-(4-morpholinylsulfonyl)phenyl]-3-phenylurea
N-[6-(diethylsulfamoyl)-1,3-benzothiazol-2-yl]-2-thiophenecarboxamide
N-[6-(diethylsulfamoyl)-1,3-benzothiazol-2-yl]-2-thiophenecarboxamide
2-[4-[(4-Chlorophenyl)methoxy]phenyl]-5-(4-morpholinyl)-4-oxazolecarbonitrile
2-[4-[(4-Chlorophenyl)methoxy]phenyl]-5-(4-morpholinyl)-4-oxazolecarbonitrile
3-[(2,6-dimethyl-4-morpholinyl)sulfonyl]-N-(5-methyl-2-thiazolyl)benzamide
3-[(2,6-dimethyl-4-morpholinyl)sulfonyl]-N-(5-methyl-2-thiazolyl)benzamide
4-(2,4-dichlorophenoxy)-N-[(1E)-(3-nitrophenyl)methylene]butanohydrazide
4-(2,4-dichlorophenoxy)-N-[(1E)-(3-nitrophenyl)methylene]butanohydrazide
3-(3-Chloro-2-methylphenyl)-1-[(4-methylphenyl)methyl]-1-(3-pyridinylmethyl)thiourea
3-(3-Chloro-2-methylphenyl)-1-[(4-methylphenyl)methyl]-1-(3-pyridinylmethyl)thiourea
2-(2-methoxyethyl)-9-methyl-1-oxo-N-(thiophen-2-ylmethyl)-4-pyrido[3,4-b]indolecarboxamide
2-(2-methoxyethyl)-9-methyl-1-oxo-N-(thiophen-2-ylmethyl)-4-pyrido[3,4-b]indolecarboxamide
2-[[5-(6-methyl-1H-benzimidazol-2-yl)-2-pyridinyl]thio]-N-(4-methyl-2-thiazolyl)acetamide
2-[[5-(6-methyl-1H-benzimidazol-2-yl)-2-pyridinyl]thio]-N-(4-methyl-2-thiazolyl)acetamide
(5-Chloro-2-hydroxyphenyl)-[2-ethyl-3-(4-fluorophenyl)-6-pyrazolo[1,5-a]pyrimidinyl]methanone
(5-Chloro-2-hydroxyphenyl)-[2-ethyl-3-(4-fluorophenyl)-6-pyrazolo[1,5-a]pyrimidinyl]methanone
2-[[5-(4-methylphenyl)-3-thiazolo[2,3-c][1,2,4]triazolyl]thio]-N-(6-methyl-2-pyridinyl)acetamide
2-[[5-(4-methylphenyl)-3-thiazolo[2,3-c][1,2,4]triazolyl]thio]-N-(6-methyl-2-pyridinyl)acetamide
3,6-Diamino-10-(3-carboxypropyl)acridinium perchlorate
3,6-Diamino-10-(3-carboxypropyl)acridinium perchlorate
Tetraethyl [(3-hydroxy-2-pyridyl)amino]methanediphosphonate
Tetraethyl [(3-hydroxy-2-pyridyl)amino]methanediphosphonate
2-(Acetylamino)-4-O-[(4,5-didehydro-1-deoxy-beta-D-glucopyranuronic acid)-1-yl]-2-deoxy-D-glucopyranose
2-(Acetylamino)-4-O-[(4,5-didehydro-1-deoxy-beta-D-glucopyranuronic acid)-1-yl]-2-deoxy-D-glucopyranose
(2R,3R,4R)-2-[(3R,4R,5R,6R)-3-Acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxy-3,4-dihydro-2H-pyran-6-carboxylic acid
(2R,3R,4R)-2-[(3R,4R,5R,6R)-3-Acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxy-3,4-dihydro-2H-pyran-6-carboxylic acid
(2R,3R,4R)-2-[(2R,3R,4R,5R,6R)-3-Acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxy-3,4-dihydro-2H-pyran-6-carboxylic acid
(2R,3R,4R)-2-[(2R,3R,4R,5R,6R)-3-Acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxy-3,4-dihydro-2H-pyran-6-carboxylic acid
(E)-3-(6,7-dimethoxyisoquinolin-1-yl)-3-(3,4-dimethoxyphenyl)prop-2-enoic acid
(E)-3-(6,7-dimethoxyisoquinolin-1-yl)-3-(3,4-dimethoxyphenyl)prop-2-enoic acid
FASN-IN-1
FASN-IN-1
FASN-IN-1 is a fatty acid synthase (FASN) inhibitor extracted from patent WO2015134790A1, compound 56[1].
LY3020371 (hydrochloride)
LY3020371 (hydrochloride)
LY3020371 hydrochloride is a potent, selective metabotropic glutamate 2/3 receptor (mGlu2/3) antagonist with Ki of 5.3 and 2.5 nM, potently blocks cAMP formation with IC50 of 16.2 nM[1]. LY3020371 hydrochloride exerts an antidepressant-like signature in vivo[2].
MMRi62
MMRi62
MMRi62, a ferroptosis inducer targeting MDM2-MDM4 (negative regulators of tumor suppressor p53). MMRi62 shows a P53-independent pro-apoptotic activity against pancreatic ductal adenocarcinoma (PDAC) cells and induce autophagy. MMRi62 inducesferroptosis, resulting in a increase of reactive oxygen and lysosomal degradation of ferritin heavy chain (FTH1). MMRi62 also leads to proteasomal degradation of mutant p53, also inhibits orthotopic xenograft PDAC mouse model in vivo with high frequency mutation characteristics of KRAS and TP53.12[1][2].
(2s,3r)-9'-methyl-3-phenyl-1',9',12'-triazaspiro[oxirane-2,10'-tetracyclo[9.8.0.0²,⁷.0¹³,¹⁸]nonadecane]-2',4',6',11',13',15',17'-heptaene-8',19'-dione
(2s,3r)-9'-methyl-3-phenyl-1',9',12'-triazaspiro[oxirane-2,10'-tetracyclo[9.8.0.0²,⁷.0¹³,¹⁸]nonadecane]-2',4',6',11',13',15',17'-heptaene-8',19'-dione
[(2-{5-[carboxy(phenyl)methylidene]-1,3-dioxolan-4-ylidene}-1-hydroxy-2-phenylethylidene)amino]acetic acid
[(2-{5-[carboxy(phenyl)methylidene]-1,3-dioxolan-4-ylidene}-1-hydroxy-2-phenylethylidene)amino]acetic acid
n-sulfo{[(3as,4r,10as)-5,10,10-trihydroxy-2,6-diimino-hexahydropyrrolo[1,2-c]purin-4-yl]methoxy}carboximidic acid
n-sulfo{[(3as,4r,10as)-5,10,10-trihydroxy-2,6-diimino-hexahydropyrrolo[1,2-c]purin-4-yl]methoxy}carboximidic acid
(2e)-2-cyano-2-(2-{[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}ethylidene)ethyl 4-hydroxybenzoate
(2e)-2-cyano-2-(2-{[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}ethylidene)ethyl 4-hydroxybenzoate
2-cyano-2-(2-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}ethylidene)ethyl 4-hydroxybenzoate
2-cyano-2-(2-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}ethylidene)ethyl 4-hydroxybenzoate
11-hydroxy-20-(1-hydroxyethyl)-9-methyl-4,8-dioxa-21-azahexacyclo[10.9.1.0²,¹⁰.0³,⁷.0¹⁶,²².0¹⁷,²¹]docosa-1,10,12(22),14,16-pentaene-5,13-dione
11-hydroxy-20-(1-hydroxyethyl)-9-methyl-4,8-dioxa-21-azahexacyclo[10.9.1.0²,¹⁰.0³,⁷.0¹⁶,²².0¹⁷,²¹]docosa-1,10,12(22),14,16-pentaene-5,13-dione
12-[2-(dimethylamino)ethyl]-13,14-dimethoxy-3,5,16-trioxapentacyclo[9.6.2.0²,⁶.0⁸,¹⁸.0¹⁵,¹⁹]nonadeca-1,6,8(18),9,11(19),12,14-heptaen-17-one
12-[2-(dimethylamino)ethyl]-13,14-dimethoxy-3,5,16-trioxapentacyclo[9.6.2.0²,⁶.0⁸,¹⁸.0¹⁵,¹⁹]nonadeca-1,6,8(18),9,11(19),12,14-heptaen-17-one
({2-[(4e,5e)-5-[carboxy(phenyl)methylidene]-1,3-dioxolan-4-ylidene]-1-hydroxy-2-phenylethylidene}amino)acetic acid
({2-[(4e,5e)-5-[carboxy(phenyl)methylidene]-1,3-dioxolan-4-ylidene]-1-hydroxy-2-phenylethylidene}amino)acetic acid
(3r)-3-cyano-2-methylidene-3-{[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}propyl 4-hydroxybenzoate
(3r)-3-cyano-2-methylidene-3-{[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}propyl 4-hydroxybenzoate
[(3as,4r,9r)-10,10-dihydroxy-2,6-diimino-9-(sulfooxy)-hexahydro-1h-pyrrolo[1,2-c]purin-4-yl]methoxycarboximidic acid
[(3as,4r,9r)-10,10-dihydroxy-2,6-diimino-9-(sulfooxy)-hexahydro-1h-pyrrolo[1,2-c]purin-4-yl]methoxycarboximidic acid
({2-[(5e)-5-[carboxy(phenyl)methylidene]-1,3-dioxolan-4-ylidene]-1-hydroxy-2-phenylethylidene}amino)acetic acid
({2-[(5e)-5-[carboxy(phenyl)methylidene]-1,3-dioxolan-4-ylidene]-1-hydroxy-2-phenylethylidene}amino)acetic acid
3-[(2,5-dihydroxy-3-methyl-1,4-benzodiazepin-3-yl)methyl]-2,3-dihydroxy-4,1-benzoxazepin-5-one
3-[(2,5-dihydroxy-3-methyl-1,4-benzodiazepin-3-yl)methyl]-2,3-dihydroxy-4,1-benzoxazepin-5-one
3-cyano-2-methylidene-3-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}propyl 4-hydroxybenzoate
3-cyano-2-methylidene-3-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}propyl 4-hydroxybenzoate
[(3as,4r,9r,10as)-10,10-dihydroxy-2,6-diimino-9-(sulfooxy)-hexahydro-1h-pyrrolo[1,2-c]purin-4-yl]methoxycarboximidic acid
[(3as,4r,9r,10as)-10,10-dihydroxy-2,6-diimino-9-(sulfooxy)-hexahydro-1h-pyrrolo[1,2-c]purin-4-yl]methoxycarboximidic acid
(2s,3s)-9'-methyl-3-phenyl-1',9',12'-triazaspiro[oxirane-2,10'-tetracyclo[9.8.0.0²,⁷.0¹³,¹⁸]nonadecane]-2',4',6',11',13',15',17'-heptaene-8',19'-dione
(2s,3s)-9'-methyl-3-phenyl-1',9',12'-triazaspiro[oxirane-2,10'-tetracyclo[9.8.0.0²,⁷.0¹³,¹⁸]nonadecane]-2',4',6',11',13',15',17'-heptaene-8',19'-dione
[(3ar,9r,10as)-10,10-dihydroxy-2,6-diimino-9-(sulfooxy)-hexahydro-1h-pyrrolo[1,2-c]purin-4-yl]methoxycarboximidic acid
[(3ar,9r,10as)-10,10-dihydroxy-2,6-diimino-9-(sulfooxy)-hexahydro-1h-pyrrolo[1,2-c]purin-4-yl]methoxycarboximidic acid
6-amino-10,10-dihydroxy-2-imino-4-{[(sulfo-c-hydroxycarbonimidoyl)oxy]methyl}-1h,3h,3ah,4h,8h,9h-pyrrolo[1,2-c]purin-5-ium-5-olate
6-amino-10,10-dihydroxy-2-imino-4-{[(sulfo-c-hydroxycarbonimidoyl)oxy]methyl}-1h,3h,3ah,4h,8h,9h-pyrrolo[1,2-c]purin-5-ium-5-olate
(2s)-2-{[(6-bromo-1h-indol-3-yl)(hydroxy)methylidene]amino}-5-carbamimidamidopentanoic acid
(2s)-2-{[(6-bromo-1h-indol-3-yl)(hydroxy)methylidene]amino}-5-carbamimidamidopentanoic acid
[(3as,4r,9s,10as)-10,10-dihydroxy-2,6-diimino-9-(sulfooxy)-hexahydro-1h-pyrrolo[1,2-c]purin-4-yl]methoxycarboximidic acid
[(3as,4r,9s,10as)-10,10-dihydroxy-2,6-diimino-9-(sulfooxy)-hexahydro-1h-pyrrolo[1,2-c]purin-4-yl]methoxycarboximidic acid
9'-methyl-3-phenyl-1',9',12'-triazaspiro[oxirane-2,10'-tetracyclo[9.8.0.0²,⁷.0¹³,¹⁸]nonadecane]-2',4',6',11',13',15',17'-heptaene-8',19'-dione
9'-methyl-3-phenyl-1',9',12'-triazaspiro[oxirane-2,10'-tetracyclo[9.8.0.0²,⁷.0¹³,¹⁸]nonadecane]-2',4',6',11',13',15',17'-heptaene-8',19'-dione
(8r,9s)-8-[2,2-dihydroxy-2-(sulfoamino)ethyl]-6,11-diimino-4,5,7,10-tetraazatricyclo[7.3.0.0¹,⁵]dodec-3-ene-2,2,7-triol
(8r,9s)-8-[2,2-dihydroxy-2-(sulfoamino)ethyl]-6,11-diimino-4,5,7,10-tetraazatricyclo[7.3.0.0¹,⁵]dodec-3-ene-2,2,7-triol
n-sulfo({5,10,10-trihydroxy-2,6-diimino-hexahydropyrrolo[1,2-c]purin-4-yl}methoxy)carboximidic acid
n-sulfo({5,10,10-trihydroxy-2,6-diimino-hexahydropyrrolo[1,2-c]purin-4-yl}methoxy)carboximidic acid
methyl 5-(6,7-dimethoxyisoquinoline-1-carbonyl)-2h-1,3-benzodioxole-4-carboxylate
methyl 5-(6,7-dimethoxyisoquinoline-1-carbonyl)-2h-1,3-benzodioxole-4-carboxylate
2-{[(6-bromo-1h-indol-3-yl)(hydroxy)methylidene]amino}-5-carbamimidamidopentanoic acid
2-{[(6-bromo-1h-indol-3-yl)(hydroxy)methylidene]amino}-5-carbamimidamidopentanoic acid
n-(1,1,15,15-tetrachloropentadec-1-en-3,12-diyn-8-yl)ethanimidic acid
n-(1,1,15,15-tetrachloropentadec-1-en-3,12-diyn-8-yl)ethanimidic acid
