Chemical Formula: C8H12N2O4Pt

Chemical Formula C8H12N2O4Pt

Found 2 metabolite its formula value is C8H12N2O4Pt

Oxaliplatin

(3aR,7aR)-octahydro-2,5-dioxaspiro[cyclohexa[d]1,3-diaza-2-platinacyclopentane-2,1-cyclopentane]-3,4-dione

C8H12N2O4Pt (395.0444882)


Oxaliplatin is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin. It is typically administered in combination with fluorouracil and leucovorin in a combination known as Folfox for the treatment of colorectal cancer. Compared to cisplatin the two amine groups are replaced by cyclohexyldiamine for improved antitumour activity. The chlorine ligands are replaced by the oxalato bidentate derived from oxalic acid in order to improve water solubility. Oxaliplatin is marketed by Sanofi-Aventis under the trademark Eloxatin®.