Exact Mass: 378.9068726

Exact Mass Matches: 378.9068726

Found 17 metabolites which its exact mass value is equals to given mass value 378.9068726, within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error 0.01 dalton.

Trichlormethiazide

6-chloro-3-(dichloromethyl)-1,1-dioxo-3,4-dihydro-2H-1λ⁶,2,4-benzothiadiazine-7-sulfonamide

C8H8Cl3N3O4S2 (378.9021818)


Trichlormethiazide is only found in individuals that have used or taken this drug. It is a thiazide diuretic with properties similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p830)Trichlormethiazide appears to block the active reabsorption of chloride and possibly sodium in the ascending loop of Henle, altering electrolyte transfer in the proximal tubule. This results in excretion of sodium, chloride, and water and, hence, diuresis. As a diuretic, Trichloromethiazide inhibits active chloride reabsorption at the early distal tubule via the Na-Cl cotransporter, resulting in an increase in the excretion of sodium, chloride, and water. Thiazides like Trichloromethiazide also inhibit sodium ion transport across the renal tubular epithelium through binding to the thiazide sensitive sodium-chloride transporter. This results in an increase in potassium excretion via the sodium-potassium exchange mechanism. The antihypertensive mechanism of Trichloromethiazide is less well understood although it may be mediated through its action on carbonic anhydrases in the smooth muscle or through its action on the large-conductance calcium-activated potassium (KCa) channel, also found in the smooth muscle. C - Cardiovascular system > C03 - Diuretics > C03A - Low-ceiling diuretics, thiazides > C03AA - Thiazides, plain D045283 - Natriuretic Agents > D004232 - Diuretics > D049993 - Sodium Chloride Symporter Inhibitors C78275 - Agent Affecting Blood or Body Fluid > C448 - Diuretic > C49185 - Thiazide Diuretic D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents D002317 - Cardiovascular Agents > D045283 - Natriuretic Agents D049990 - Membrane Transport Modulators

   
   

CLORSULON

CLORSULON

C8H8Cl3N3O4S2 (378.9021818)


D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000871 - Anthelmintics C254 - Anti-Infective Agent > C276 - Antiparasitic Agent > C250 - Antihelminthic Agent D000890 - Anti-Infective Agents > D013424 - Sulfanilamides

   

Clorsulon

4-amino-6-(1,2,2-Trichloroethenyl)benzene-1,3-disulphonamide

C8H8Cl3N3O4S2 (378.9021818)


D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000871 - Anthelmintics C254 - Anti-Infective Agent > C276 - Antiparasitic Agent > C250 - Antihelminthic Agent D000890 - Anti-Infective Agents > D013424 - Sulfanilamides

   

2-(4-Bromo-2-iodophenyl)-4,4-dimethyl-4,5-dihydrooxazole

2-(4-Bromo-2-iodophenyl)-4,4-dimethyl-4,5-dihydrooxazole

C11H11BrINO (378.9068726)


   

tungsten boride

tungsten boride

BW2 (378.911211)


   

3-[4-[(4-BROMOPHENYL)THIO]-3-NITROPHENYL]ACRYLIC ACID

3-[4-[(4-BROMOPHENYL)THIO]-3-NITROPHENYL]ACRYLIC ACID

C15H10BrNO4S (378.95138800000007)


   

METHYL 5-IODO-3-(2,2,2-TRIFLUOROACETAMIDO)THIOPHENE-2-CARBOXYLATE

METHYL 5-IODO-3-(2,2,2-TRIFLUOROACETAMIDO)THIOPHENE-2-CARBOXYLATE

C8H5F3INO3S (378.8987006000001)


   

ETHYL 2-BROMO-4-(4-(TRIFLUOROMETHYL)PHENYL)THIAZOLE-5-CARBOXYLATE

ETHYL 2-BROMO-4-(4-(TRIFLUOROMETHYL)PHENYL)THIAZOLE-5-CARBOXYLATE

C13H9BrF3NO2S (378.94894300000004)


   

Erbium(III) chloride hexahydrate

Erbium(III) chloride hexahydrate

Cl3ErH12O6 (378.9002492)


   

7-aminonaphthalene-1,3-disulfonic acid, potassium salt

7-aminonaphthalene-1,3-disulfonic acid, potassium salt

C10H7K2NO6S2 (378.8988962)


   
   

(3R)-6-chloro-3-(dichloromethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide

(3R)-6-chloro-3-(dichloromethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide

C8H8Cl3N3O4S2 (378.9021818)


   

(2Z,4Z)-3,8,8-trichloro-7-(4-chlorophenyl)-2-hydroxy-6-oxoocta-2,4,7-trienoate

(2Z,4Z)-3,8,8-trichloro-7-(4-chlorophenyl)-2-hydroxy-6-oxoocta-2,4,7-trienoate

C14H7Cl4O4- (378.9098442)


   

6-Oxo-2-hydroxy-7-(4-chlorophenyl)-3,8,8-trichloroocta-2E,4E,7E-trienoate

6-Oxo-2-hydroxy-7-(4-chlorophenyl)-3,8,8-trichloroocta-2E,4E,7E-trienoate

C14H7Cl4O4- (378.9098442)


   

trichlormethiazide

trichlormethiazide

C8H8Cl3N3O4S2 (378.9021818)


C - Cardiovascular system > C03 - Diuretics > C03A - Low-ceiling diuretics, thiazides > C03AA - Thiazides, plain D045283 - Natriuretic Agents > D004232 - Diuretics > D049993 - Sodium Chloride Symporter Inhibitors C78275 - Agent Affecting Blood or Body Fluid > C448 - Diuretic > C49185 - Thiazide Diuretic D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents D002317 - Cardiovascular Agents > D045283 - Natriuretic Agents D049990 - Membrane Transport Modulators