Exact Mass: 374.1365462
Exact Mass Matches: 374.1365462
Found 500 metabolites which its exact mass value is equals to given mass value 374.1365462,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Swertiamarin
Swertiamarin is a glycoside. Swertiamarin is a natural product found in Lonicera japonica, Fontanesia philliraeoides, and other organisms with data available. See also: Centaurium erythraea whole (part of). Swertiamarin, a secoiridoid glycoside found in genera of Enicostemma littorale, confers anti-hyperglycemic and anti-hyperlipidemic effects[1]. Swertiamarin, a secoiridoid glycoside found in genera of Enicostemma littorale, confers anti-hyperglycemic and anti-hyperlipidemic effects[1].
Gardoside
Gardoside is a glycoside. Gardoside is a natural product found in Plantago atrata, Gardenia jasminoides, and other organisms with data available.
(-)-Wikstromol
(-)-Wikstromol is found in fruits. (-)-Wikstromol is obtained from Pinus palustris (pitch pine) and Carissa edulis (agam obtained from Pinus palustris (pitch pine) and Carissa edulis (agam). (-)-Wikstromol is found in fruits and sesame.
Geniposidic acid
Geniposidic acid is found in beverages. Geniposidic acid is a constituent of Genipa americana (genipap) Constituent of Genipa americana (genipap). Geniposidic acid is found in beverages and fruits. Geniposidic acid has radiation protection and anti-cancer activity. Geniposidic acid has radiation protection and anti-cancer activity.
Secologanate
Kievitone hydrate
Isolated from Phaseolus mungo (mung bean). Kievitone hydrate is found in pulses, lima bean, and gram bean. Kievitone hydrate is found in gram bean. Kievitone hydrate is isolated from Phaseolus mungo (mung bean).
Portulacaxanthin II
Portulacaxanthin II is involved in betaxanthin biosynthesis (via dopaxanthin) pathway. This pathway demonstrates the formation of betaxanthins such as portulacaxanthin II and dopaxanthin by means of non-enzymatic condensation from the amino acids L-tyrosine and L-DOPA, respectively. Tyrosinases have been described as capable to use those betaxanthins [ GandiaHerr05a ] as substrates for further metabolization. [HMDB]. Portulacaxanthin II is found in many foods, some of which are pineappple sage, peppermint, japanese pumpkin, and medlar. Portulacaxanthin II is involved in betaxanthin biosynthesis (via dopaxanthin) pathway. This pathway demonstrates the formation of betaxanthins such as portulacaxanthin II and dopaxanthin by means of non-enzymatic condensation from the amino acids L-tyrosine and L-DOPA, respectively. Tyrosinases have been described as capable to use those betaxanthins [ GandiaHerr05a ] as substrates for further metabolization.
N-(3-Benzooxazol-2-yl-4-hydroxy-phenyl)-2-p-tolyloxyacetamide
9-mercapto-11,17-dioxoandrosta-3,5-dien-3-yl acetate
Famoxadone
D010575 - Pesticides > D005659 - Fungicides, Industrial > D000073739 - Strobilurins CONFIDENCE standard compound; INTERNAL_ID 403; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5208; ORIGINAL_PRECURSOR_SCAN_NO 5203 CONFIDENCE standard compound; INTERNAL_ID 403; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5187; ORIGINAL_PRECURSOR_SCAN_NO 5183 CONFIDENCE standard compound; INTERNAL_ID 403; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5271; ORIGINAL_PRECURSOR_SCAN_NO 5269 CONFIDENCE standard compound; INTERNAL_ID 403; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5195; ORIGINAL_PRECURSOR_SCAN_NO 5192 CONFIDENCE standard compound; EAWAG_UCHEM_ID 3049
Cyproterone
An anti-androgen that, in the form of its acetate (cyproterone acetate), also has progestational properties. It is used in the treatment of hypersexuality in males, as a palliative in prostatic carcinoma, and, in combination with estrogen, for the therapy of severe acne and hirsutism in females. [Pubchem] G - Genito urinary system and sex hormones > G03 - Sex hormones and modulators of the genital system > G03H - Antiandrogens > G03HA - Antiandrogens, plain D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006727 - Hormone Antagonists > D000726 - Androgen Antagonists C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C146993 - Androgen Receptor Inhibitor C147908 - Hormone Therapy Agent > C547 - Hormone Antagonist > C242 - Anti-Androgen
8-Hydroxypinoresinol
8-Hydroxypinoresinol is found in olive. 8-Hydroxypinoresinol is a constituent of bark of Olea europaea (olive).
N-[(5-Hydroxy-2-pyridinyl)methyl]adenosine
C16H18N6O5 (374.13386180000003)
N-[(5-Hydroxy-2-pyridinyl)methyl]adenosine is found in mushrooms. N-[(5-Hydroxy-2-pyridinyl)methyl]adenosine is isolated from Armillaria mellea (honey mushroom). Isolated from Armillaria mellea (honey mushroom). N-[(5-Hydroxy-2-pyridinyl)methyl]adenosine is found in mushrooms.
3',4',5,7,8-Pentamethoxyflavanone
3,4,5,7,8-Pentamethoxyflavanone is found in citrus. 3,4,5,7,8-Pentamethoxyflavanone is a constituent of a Citrus sp. (Dancy tangerine). Constituent of a Citrus species (Dancy tangerine). 3,4,5,7,8-Pentamethoxyflavanone is found in citrus.
Kievitol
Kievitol is found in lima bean. Kievitol is isolated from Phaseolus lunatus (butter bean). Isolated from Phaseolus lunatus (butter bean). Kievitol is found in pulses and lima bean.
Succinylaminoimidazole carboxamide riboside
Succinylaminoimidazole carboxamide riboside, also known as SAICAr, is the riboside form of the better known compound SAICAR (the ribotide). Ribosides chemically resemble ribotides except they do not contain a phosphate group. The appearance of succinylaminoimidazolecarboxamide riboside (SAICAriboside) and succinyladenosine (S-Ado) in cerebrospinal fluid, in urine, and, to a lesser extent, in plasma is characteristic of a heritable deficiency known as adenylosuccinate lyase deficiency (ADSL). Adenylosuccinate lyase deficiency is responsible for a range of symptoms that involve psychomotor retardation, often accompanied by epileptic seizures, and autistic features. In adenylosuccinate lyase deficiency it is believed that the buildup of SAICAr causes neurotoxic effects. In the severely affected individuals, the concentration levels of SAICAr and S-Ado are comparable, whereas in people with milder forms of the disease, the concentration of S-Ado is more than double that of those more severely affected, while SAICAr concentration levels remain comparable. Therefore, when present in sufficiently high levels, SAICAr can act as a metabotoxin and an acidogen. An acidogen is an acidic compound that induces acidosis, which has multiple adverse effects on many organ systems. A metabotoxin is an endogenously produced metabolite that causes adverse health effects at chronically high levels. Acidosis typically occurs when arterial pH falls below 7.35. In infants with acidosis the initial symptoms include poor feeding, vomiting, loss of appetite, weak muscle tone (hypotonia), and lack of energy (lethargy). These can progress to heart, liver, and kidney abnormalities, seizures, coma, and possibly death. These are also the characteristic symptoms of untreated adenylosuccinate lyase deficiency. Many affected children with organic acidemias experience intellectual disability or delayed development.
3'-Azido-2',3'-dideoxyuridine 5'-(1,4-dihydro-1-methyl-3-pyridinecarboxylate)
C16H18N6O5 (374.13386180000003)
7'-Hydroxymatairesinol
Cyproteron
Deoxyloganin
Harmol glucuronide
hydroxymatairesinol
Swertiamarin
7-Hydroxymatairesinol
7-hydroxymatairesinol is a member of the class of compounds known as dibenzylbutyrolactone lignans. Dibenzylbutyrolactone lignans are lignan compounds containing a 3,4-dibenzyloxolan-2-one moiety. 7-hydroxymatairesinol is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). 7-hydroxymatairesinol can be found in sesame, which makes 7-hydroxymatairesinol a potential biomarker for the consumption of this food product. Hydroxymatairesinol (HMR) is a lignan found in Norway spruce (Picea abies). It is an enterolactone precursor with anticancer activities. In rats, HMR decreased the volume of induced tumours and stabilised established tumours, as well as preventing the development of new tumours. It has also shown anti-oxidant properties in vitro .
Isohydroxymatairesinol
Isohydroxymatairesinol is a member of the class of compounds known as lignan lactones. Lignan lactones are lignans that contain a lactone moiety. They include 1-aryltetralin lactones, dibenzylbutyrolactone lignans, and podophyllotoxins, among others. Isohydroxymatairesinol is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). Isohydroxymatairesinol can be found in sesame, which makes isohydroxymatairesinol a potential biomarker for the consumption of this food product.
(+)-Pinoresinolin
(+)-pinoresinolin is a member of the class of compounds known as methoxyphenols. Methoxyphenols are compounds containing a methoxy group attached to the benzene ring of a phenol moiety (+)-pinoresinolin is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). (+)-pinoresinolin can be found in burdock, which makes (+)-pinoresinolin a potential biomarker for the consumption of this food product.
secologanate
Secologanate, also known as secologanic acid, is a member of the class of compounds known as terpene glycosides. Terpene glycosides are prenol lipids containing a carbohydrate moiety glycosidically bound to a terpene backbone. Secologanate is soluble (in water) and a weakly acidic compound (based on its pKa). Secologanate can be found in a number of food items such as komatsuna, french plantain, shallot, and japanese persimmon, which makes secologanate a potential biomarker for the consumption of these food products.
Geniposidic_acid
Geniposidic acid is a terpene glycoside. Geniposidic acid is a natural product found in Avicennia officinalis, Gardenia jasminoides, and other organisms with data available. Geniposidic acid has radiation protection and anti-cancer activity. Geniposidic acid has radiation protection and anti-cancer activity.
8-epidiosbulbin E acetate
Diffractic
4-[(2,4-dimethoxy-3,6-dimethylphenyl)-oxomethoxy]-2-hydroxy-3,6-dimethylbenzoic acid is a carbonyl compound. Diffractaic acid is a natural product found in Alectoria ochroleuca, Ophioparma ventosa, and other organisms with data available. Diffractaic acid, a major constituent of U. longissimi, acts as an effective proapoptotic agent in various disorders research[1]. Diffractaic acid is the analgesic and antipyretic component of Usnea diffracta[2]. Diffractaic acid, a major constituent of U. longissimi, acts as an effective proapoptotic agent in various disorders research[1]. Diffractaic acid is the analgesic and antipyretic component of Usnea diffracta[2].
7-Hydroxy-5,8-dimethoxy-6-methyl-3-(2-hydroxy-4-methoxybenzyl)chroman-4-one
[2aR-(2aalpha,3beta,4alpha,7balpha)]-3-(beta-D-Gucopyranosyloxy)-2a,3,4,4a,5,7b-hexahydro-4a-hydroxy-4-methyl-1H-2,6-dioxacyclopent[cd]inden-1-one
Hyuganin D
Hyuganin D is a natural product found in Musineon divaricatum with data available.
3,5,7,4-Tetrahydroxy-8-(3-hydroxy-3-methylbutyl)flavanone
1alpha-Hydroxy-2alpha,4alpha-guaicyl-3,7-dioxabicyclo[3.3.0]octane
5,7-Dimethoxy-3-(3,4,5-trimethoxyphenylmethyl)phthalide
7-Hydroxy-3-(2-hydroxy-3-methoxybenzyl)-5,8-dimethoxy-6-methylchroman-4-one
6-Methoxy-3,4-dehydromurranganon-2-methylpropanoate
Rubone
relative retention time with respect to 9-anthracene Carboxylic Acid is 1.378 relative retention time with respect to 9-anthracene Carboxylic Acid is 1.380 relative retention time with respect to 9-anthracene Carboxylic Acid is 1.382
1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(2,4,5-trimethoxyphenyl)prop-2-en-1-one
Diffractaic acid
Diffractaic acid, a major constituent of U. longissimi, acts as an effective proapoptotic agent in various disorders research[1]. Diffractaic acid is the analgesic and antipyretic component of Usnea diffracta[2]. Diffractaic acid, a major constituent of U. longissimi, acts as an effective proapoptotic agent in various disorders research[1]. Diffractaic acid is the analgesic and antipyretic component of Usnea diffracta[2].
3,6-bis(4-hydroxy-3-methoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-4-ol
15-Ketone,16xi-alcohol-(ent-8alpha,12alphaH,15xi)-8,12-Epoxy-15-hydroxy-1-oxo-2,13-clerodadiene-16,15:18,19-diolide
4-O-beta-D-glucopyranosylsyringic acid methyl ester|methyl syringate 4-O-beta-D-glucopyranoside|methyl syringate 4-O-beta-D-glucuronopyranoside|Methyl syringate 4-O-??-D-glucopyranoside
(4aS,5R,6S)-5-ethenyl-6-(beta-D-glucopyranosyloxy)-4,4a,5,6-tetrahydro-3-hydroxy-1H,3H-pyrano[3,4-c]pyran-1-one|secologanic acid
methyl (3R,8R,9S,14R,15S)-8,14,15-trihydroxy-3,9-dimethyl-5,11-dioxo-4,10-dioxadeca (6E,12E)-dienoate|seco-macrosphelide
3,3-dimethoxy-4,4,9-trihydroxy-7,9-epoxylignan-7-one
2-hydroxy-3,4,3,4,6-pentamethoxy-trans(?)-chalcone|2-Hydroxy-3,4,3,4,6-pentamethoxy-trans(?)-chalkon|2-hydroxy-3,4,3,4,6-pentamethoxychalcone
1,2-Dimethoxy-12-methyl-12,13-dihydro-[1,3]dioxolo[4,5:4,5]benzo[1,2-c]phenanthridin-13-carbonitril|1,2-dimethoxy-12-methyl-12,13-dihydro-[1,3]dioxolo[4,5:4,5]benzo[1,2-c]phenanthridine-13-carbonitrile|Cheleritrin-pseudocyanid|Chelerythrin-4-cyanin|chelerythrine phi-cyanide|Chelerythrine Psi-cyanid|Pseudocyanid von Chelerythrin
2-O-Acetyl-1-O-isobutyryl-6-O-tiglyl-beta-D-glucopyranose
(+-)-2,3,4,6,7-Pentamethoxyisoflavanon|2,3,4,6,7-Pentamethoxyisoflavan-4-on|6,7-dimethoxy-3-(2,3,4-trimethoxy-phenyl)-chroman-4-one
2-(3,4-dimethoxy-benzyl)-2,6,7-trimethoxy-benzofuran-3-one|Penta-Me ether-Nigrescin
(+)-saudin|(-)-(1R,4R,5S,7R,9S,13S,16R)-7-(3-furanyl)-4,13,16-trimethyl-2,8,11,17-tetraoxapentacyclo<7.6.1.11,7.05,16.09,13>heptadeca-3,12-dione|(-)-(1R,4R,5S,7R,9S,13S,16R)-7-(3-furanyl)-4,13,16-trimethyl-2,8,11,17-tetraoxapentacyclo[7.6.1.11,7.05,16.09,13]heptadeca-3,12-dione|Saudin
(5S,6R,7R,8R,2RS,3RS)-2-oxo-3,4-epoxy-8-(2-methyl-2,3-epoxybutanoyl)-guaia-10(14),11(13)-dien-6,12-olide
7,8-dimethyl-10-<(3,4,5-trihydroxytetrahydrofuran-2-yl)methyl>isoalloxazin|7,8-dimethyl-10-[(3,4,5-trihydroxytetrahydrofuran-2-yl)methyl]isoalloxazin
C17H18N4O6 (374.12262880000003)
(-)-3-O-Demethyl-5-methoxymatairesinol|(8R,8R)-(-)-3-O-demethyl-5-methoxymatairesinol
(2R,3S)-Dihydro-2-(3,5-dimethoxy-4-hydroxyphenyl)-7-methoxy-5-acetyl-benzofuran
Vladinol D
A lignan which consists of tetrahydrofuran skeleton substituted by a hydroxymethyl group at position 4, a 4-hydroxy-3-methoxyphenyl group at position 5 and a 4-hydroxy-3-methoxybenzoyl group at position 3. It has been isolated from the roots of Rubia yunnanensis.
3-[4-[1,3-dihydroxy-1-(4-hydroxy-3-methoxyphenyl)propan-2-yl]oxy-3-methoxyphenyl]prop-2-enal
(3S,4R,4aR,4bS,5R,7aR,10aS,12aS)-3-(furan-3-yl)-3,4,4a,5,7a,11,12,12a-octahydro-4,5-dihydroxy-4a-methyl-1H-[2]benzofuro[4,3a-f]isochromene-1,8(4bH)-dione|15,16-epoxy-1beta,11beta-dihydroxy-8alphaH,12betaH-cleroda-2,13(16),14-triene-17,12:18,19-diolide|splendidin A
O1-beta-D-Glucopyranosyl-D-glycero-D-manno-heptit|O1-beta-D-glucopyranosyl-D-glycero-D-manno-heptitol
C13H26O12 (374.14241960000004)
(1S,4aS,7aS)-1-(beta-D-glucopyranosyloxy)-1,4a,5,7a-tetrahydro-7-(hydroxymethyl)cyclopenta[c]pyran-4-carboxylic acid|geniposidic acid
4alpha,10alpha-dihydroxy-1alpha,2alpha-epoxy-5alpha,7alphaH-guaia-11(13)-en-12,6alpha-olide
5S,6R,7R,8R,11R-(-)-2-oxo-8-tigloyloxyguaia-1(10),3-diene-6,12-olide-14-carboxylic acid
5,7-Dihydroxy-3-(4-hydroxy-3,5-dimethoxybenzyl)-6,8-dimethylchroman-4-one
3-Hydroxy-3-(4-methoxybenzyl)-5,6,7-trimethoxy-2H-1-benzopyran-4(3H)-one
8-O-beta-D-glucopyranosyl-(R)-(+)-3,4,8-trihydroxymethyl phenylpropionate
1,5-bis(2,4-dihydroxyphenyl)-3-methoxycarbonyl-4-methoxypent-2-ene
5alpha-hydroxy-6alpha-angeloyloxy-Delta-4,15-isogoyazensanolide
(R)-2-(3,4-dimethoxyphenyl)propane-1,3-diol-1-O-beta-D-glucopyranoside
3,8-epoxy-5-hydroxyvalechlorin-1-yl isovalerate|jatamanin O|rel-(2R,4S,4aS,5S,7S,7aS)-7-(acetyloxy)-7a-(chloromethyl)hexahydro-8-methylene-2,5-methanocyclopenta-1,3-dioxin-4-yl 3-methylbutanoate
Me glycoside,4,6-O-benzylidene,2-mesyl-3-O-Methylgalactose
6,7-Dimethoxy-8-[1-[(isobutyryl)oxy]-3-methyl-2-oxo-3-butenyl]-2H-1-benzopyran-2-one
(7R,8S,8S)-3,4-methylenedioxy-4-methoxy-3,8,9-trihydroxy-8.8,7-O-9-lignan|mandshuricol B
2-Hydroxy-2-(3,4-dihydroxyphenyl)methyl-3-(3,4-dimethoxyphenyl)methyl-gamma-butyrolactone
(3S,5S,6aS,8S,10R,10aR)-5-(furan-3-yl)-4,5,6,6a,9,10-hexahydro-8,10-dihydroxy-8-methylspiro[furan-3(2H),7,(8H)-[1H]naphtho[1,8a-c]furan]-2,3(5H)-dionekinalborin B
(1R)-1-(4-hydroxy-3,5-dimethoxyphenyl)propan-1-ol 4-O-beta-D-glucopyranoside|(1R)-1-(4-Hydroxy-3,5-dimethoxyphenyl)propan-1-ol 4-O-??-D-glucopyranoside
3(R)-isobutyryloxy-4(R)-acetoxy-3,4-dihydroseselin|Bocconin
8beta-(2,3-epoxy-2-methylbutyryloxy)-grazielolide|8beta-<2,3-epoxy-2-methylbutyryloxy>-grazielolide
1alpha,11-epoxy-1beta,20-dihydroxy-5betaH-picrasa-3,9(11)-diene-2,12,16-trione|Shinjulactone F
5,6,7,8-tetramethoxy-2-(4-methoxyphenyl)chroman-4-one
5, 7-Dimethoxy-3-(3, 4, 5-trimethoxybenzyl)phthalide
3-[5-[(threo) 2,3-dihydro-2-(4-hydroxy-3-methoxyphenyl)-3-hydroxymethyl-7-methoxybenzofuranyl]]-propanoic acid
6alpha-(2-(1)-hydroxyethylacryloyloxy)-goyazensanolide|6alpha-<2-(1)-hydroxyethylacryloyloxy>-goyazensanolide
6-(1,2-dihydroxy-ethyl)-8-D-ribitol-1-yl-1H,8H-pteridine-2,4,7-trione|Photolumazin A
Arborescosidic acid
Arborescosidic acid is a natural product found in Plantago atrata, Plantago maritima, and Globularia trichosantha with data available.
PD86RC383X
4-[(2,4-dimethoxy-3,6-dimethylphenyl)-oxomethoxy]-2-hydroxy-3,6-dimethylbenzoic acid is a carbonyl compound. Diffractaic acid is a natural product found in Alectoria ochroleuca, Ophioparma ventosa, and other organisms with data available. Diffractaic acid, a major constituent of U. longissimi, acts as an effective proapoptotic agent in various disorders research[1]. Diffractaic acid is the analgesic and antipyretic component of Usnea diffracta[2]. Diffractaic acid, a major constituent of U. longissimi, acts as an effective proapoptotic agent in various disorders research[1]. Diffractaic acid is the analgesic and antipyretic component of Usnea diffracta[2].
wikstromol
Nortrachelogenin is a lignan. Nortrachelogenin is a natural product found in Passerina corymbosa, Didymochlaena truncatula, and other organisms with data available. (+)-Nortrachelogenin is a natural product found in Carissa carandas, Daphne oleoides, and other organisms with data available.
Epinortrachelogenin
Epinortrachelogenin is a natural product found in Stellera chamaejasme, Selaginella doederleinii, and Bupleurum salicifolium with data available.
Geniposidic acid
Geniposidic acid has radiation protection and anti-cancer activity. Geniposidic acid has radiation protection and anti-cancer activity.
Swertiamarin
Annotation level-1 Swertiamarin, a secoiridoid glycoside found in genera of Enicostemma littorale, confers anti-hyperglycemic and anti-hyperlipidemic effects[1]. Swertiamarin, a secoiridoid glycoside found in genera of Enicostemma littorale, confers anti-hyperglycemic and anti-hyperlipidemic effects[1].
3-hydroxy-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]oxolan-2-one
2,3,8,9,10-pentamethoxy-6a,11a-dihydro-6H-[1]benzofuro[3,2-c]chromene
[2-(2-acetyloxypropan-2-yl)-7-oxo-2,3-dihydrofuro[3,2-g]chromen-3-yl] 2-methylpropanoate
[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] 3,4,5-trimethoxybenzoate
Cyproterone
G - Genito urinary system and sex hormones > G03 - Sex hormones and modulators of the genital system > G03H - Antiandrogens > G03HA - Antiandrogens, plain D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006727 - Hormone Antagonists > D000726 - Androgen Antagonists C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C146993 - Androgen Receptor Inhibitor C147908 - Hormone Therapy Agent > C547 - Hormone Antagonist > C242 - Anti-Androgen CONFIDENCE standard compound; INTERNAL_ID 2396 CONFIDENCE standard compound; INTERNAL_ID 8745
Swertiamarine
Swertiamarin, a secoiridoid glycoside found in genera of Enicostemma littorale, confers anti-hyperglycemic and anti-hyperlipidemic effects[1]. Swertiamarin, a secoiridoid glycoside found in genera of Enicostemma littorale, confers anti-hyperglycemic and anti-hyperlipidemic effects[1].
2,3,8,9,10-pentamethoxy-6a,11a-dihydro-6H-[1]benzofuro[3,2-c]chromene
Diffractic acid
Origin: Microbe, Carboxylic acids Diffractaic acid, a major constituent of U. longissimi, acts as an effective proapoptotic agent in various disorders research[1]. Diffractaic acid is the analgesic and antipyretic component of Usnea diffracta[2]. Diffractaic acid, a major constituent of U. longissimi, acts as an effective proapoptotic agent in various disorders research[1]. Diffractaic acid is the analgesic and antipyretic component of Usnea diffracta[2].
2,3,8,9,10-pentamethoxy-6a,11a-dihydro-6H-[1]benzofuro[3,2-c]chromene [IIN-based on: CCMSLIB00000847214]
[2-(2-acetyloxypropan-2-yl)-7-oxo-2,3-dihydrofuro[3,2-g]chromen-3-yl] 2-methylpropanoate [IIN-based on: CCMSLIB00000848504]
[2-(2-acetyloxypropan-2-yl)-7-oxo-2,3-dihydrofuro[3,2-g]chromen-3-yl] 2-methylpropanoate [IIN-based: Match]
[2-(2-acetyloxypropan-2-yl)-7-oxo-2,3-dihydrofuro[3,2-g]chromen-3-yl] 2-methylpropanoate [IIN-based on: CCMSLIB00000848503]
2,3,8,9,10-pentamethoxy-6a,11a-dihydro-6H-[1]benzofuro[3,2-c]chromene [IIN-based: Match]
Ala Gly Met Pro
C15H26N4O5S (374.16238260000006)
Ala Gly Asn Asn
Ala Gly Pro Met
C15H26N4O5S (374.16238260000006)
Ala Met Gly Pro
C15H26N4O5S (374.16238260000006)
Ala Met Pro Gly
C15H26N4O5S (374.16238260000006)
Ala Asn Gly Asn
Ala Asn Asn Gly
Ala Pro Gly Met
C15H26N4O5S (374.16238260000006)
Ala Pro Met Gly
C15H26N4O5S (374.16238260000006)
Cys Gly Pro Val
C15H26N4O5S (374.16238260000006)
Cys Gly Val Pro
C15H26N4O5S (374.16238260000006)
Cys Pro Gly Val
C15H26N4O5S (374.16238260000006)
Cys Pro Val Gly
C15H26N4O5S (374.16238260000006)
Cys Val Gly Pro
C15H26N4O5S (374.16238260000006)
Cys Val Pro Gly
C15H26N4O5S (374.16238260000006)
Asp Gly Pro Ser
Asp Gly Ser Pro
Asp Pro Gly Ser
Asp Pro Ser Gly
Asp Ser Gly Pro
Asp Ser Pro Gly
Gly Ala Met Pro
C15H26N4O5S (374.16238260000006)
Gly Ala Asn Asn
Gly Ala Pro Met
C15H26N4O5S (374.16238260000006)
Gly Cys Pro Val
C15H26N4O5S (374.16238260000006)
Gly Cys Val Pro
C15H26N4O5S (374.16238260000006)
Gly Asp Pro Ser
Gly Asp Ser Pro
Gly Gly Asn Gln
Gly Gly Gln Asn
Gly Met Ala Pro
C15H26N4O5S (374.16238260000006)
Gly Met Pro Ala
C15H26N4O5S (374.16238260000006)
Gly Asn Ala Asn
Gly Asn Gly Gln
Gly Asn Asn Ala
Gly Asn Gln Gly
Gly Pro Ala Met
C15H26N4O5S (374.16238260000006)
Gly Pro Cys Val
C15H26N4O5S (374.16238260000006)
Gly Pro Asp Ser
Gly Pro Met Ala
C15H26N4O5S (374.16238260000006)
Gly Pro Ser Asp
Gly Pro Val Cys
C15H26N4O5S (374.16238260000006)
Gly Gln Gly Asn
Gly Gln Asn Gly
Gly Ser Asp Pro
Gly Ser Pro Asp
Gly Val Cys Pro
C15H26N4O5S (374.16238260000006)
Gly Val Pro Cys
C15H26N4O5S (374.16238260000006)
Met Ala Gly Pro
C15H26N4O5S (374.16238260000006)
Met Ala Pro Gly
C15H26N4O5S (374.16238260000006)
Met Gly Ala Pro
C15H26N4O5S (374.16238260000006)
Met Gly Pro Ala
C15H26N4O5S (374.16238260000006)
Met Pro Ala Gly
C15H26N4O5S (374.16238260000006)
Met Pro Gly Ala
C15H26N4O5S (374.16238260000006)
Asn Ala Gly Asn
Asn Ala Asn Gly
Asn Gly Ala Asn
Asn Gly Gly Gln
Asn Gly Asn Ala
Asn Gly Gln Gly
Asn Asn Ala Gly
Asn Asn Gly Ala
Asn Gln Gly Gly
Pro Ala Gly Met
C15H26N4O5S (374.16238260000006)
Pro Ala Met Gly
C15H26N4O5S (374.16238260000006)
Pro Cys Gly Val
C15H26N4O5S (374.16238260000006)
Pro Cys Val Gly
C15H26N4O5S (374.16238260000006)
Pro Asp Gly Ser
Pro Asp Ser Gly
Pro Gly Ala Met
C15H26N4O5S (374.16238260000006)
Pro Gly Cys Val
C15H26N4O5S (374.16238260000006)
Pro Gly Asp Ser
Pro Gly Met Ala
C15H26N4O5S (374.16238260000006)
Pro Gly Ser Asp
Pro Gly Val Cys
C15H26N4O5S (374.16238260000006)
Pro Met Ala Gly
C15H26N4O5S (374.16238260000006)
Pro Met Gly Ala
C15H26N4O5S (374.16238260000006)
Pro Ser Asp Gly
Pro Ser Gly Asp
Pro Val Cys Gly
C15H26N4O5S (374.16238260000006)
Pro Val Gly Cys
C15H26N4O5S (374.16238260000006)
Gln Gly Gly Asn
Gln Gly Asn Gly
Gln Asn Gly Gly
Ser Asp Gly Pro
Ser Asp Pro Gly
Ser Gly Asp Pro
Ser Gly Pro Asp
Ser Pro Asp Gly
Ser Pro Gly Asp
Val Cys Gly Pro
C15H26N4O5S (374.16238260000006)
Val Cys Pro Gly
C15H26N4O5S (374.16238260000006)
Val Gly Cys Pro
C15H26N4O5S (374.16238260000006)
Val Gly Pro Cys
C15H26N4O5S (374.16238260000006)
Val Pro Cys Gly
C15H26N4O5S (374.16238260000006)
Val Pro Gly Cys
C15H26N4O5S (374.16238260000006)
7-[2-TRIFLUOROMETHYL-4-(2-HYDROXYPHENYL)-1,3-DIOXAN-cis-5-YL]-HEPT-5Z-ENOIC ACID
C18H21F3O5 (374.13410120000003)
3',4',5,7,8-Pentamethoxyflavanone
AMG-1
C16H18N6O5 (374.13386180000003)
(2E,4E)-8-(6-O-inositolyl)-8-oxo-2,7-dimethyl-octadienoic acid
4-Methylphenyl 4,6-O-benzylidene-1-thio-b-D-glucopyranoside
C20H22O5S (374.11878820000004)
(E)-1-(4-(Benzyloxy)-2-hydroxyphenyl)-3-(2-methoxy-4-methylphenyl)prop-2-en-1-one
4-METHYLPHENYL4,6-O-[(R)-PHENYLMETHYLENE]-1-THIO-BETA-D-GLUCOPYRANOSIDE
C20H22O5S (374.11878820000004)
(2S,5S)-DIMETHYL 1-(2-(1,3-DIOXOISOINDOLIN-2-YL)ETHYL)PIPERIDINE-2,5-DICARBOXYLATE
1,4-bis(trimethoxysilylethyl)benzene
C16H30O6Si2 (374.15808400000003)
4-Methylphenyl 4,6-O-benzylidene-1-thio-b-D-galactopyranoside
C20H22O5S (374.11878820000004)
4-METHYL-N-(5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDIN-3-YL)BENZENESULFONAMIDE
C18H23BN2O4S (374.1471508000001)
(11ar)-(+)-10,11,12,13-tetrahydrodiindeno[7,1-de:1,7-fg][1,3,2]dioxaphosphocin-5-phenoxy
l-methionine-d3-n-fmoc (s-methyl-d3)
C20H18D3NO4S (374.13795413400004)
4-(4-Nitrophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-bis(carboxylic acid ethyl) ester
4-Methoxyphenyl 4,6-O-Benzylidene-beta-D-galactopyranoside
pentamethyl cyclohexane-1,1,3,3,5-pentacarboxylate
TRIMETHYL((4-((4-(PHENYLETHYNYL)PHENYL)ETHYNYL)PHENYL)ETHYNYL)SILANE
TERT-BUTYL 4-((1R,2R)-1-(4-CHLOROPHENYL)-1-HYDROXYPENTAN-2-YL)BENZOATE
ethyl (2S)-3-(4-aminophenyl)-2-(1,3-dioxoisoindol-2-yl)propanoate,hydrochloride
(2R,5S)-DIMETHYL 1-(2-(1,3-DIOXOISOINDOLIN-2-YL)ETHYL)PIPERIDINE-2,5-DICARBOXYLATE
3-O-(4-TOLUENESULFONYL)-2-O-ACETYL-L-METHYLFUCOSIDE
1-(2,6-Dichlorobenzyl)-3-(1-Pyrrolidinylmethyl)-1H-Indazol-6-Amine
1-[2-[(4-CHLORO-2-NITROPHENYL)AMINO]BENZOYL]-4-METHYL-PIPERAZINE
C18H19ClN4O3 (374.11456139999996)
B-(10-[1,1-Biphenyl]-4-yl-9-anthracenyl)boronic acid
6-isoquinolin-5-yl-N-phenylnaphthalene-1-carboxamide
C26H18N2O (374.14190579999996)
2,5-bis(4-biphenylyl)-1,3,4-oxadiazole
C26H18N2O (374.14190579999996)
Ethyl 4-[(4-chlorophenyl)-2-pyridinylmethoxy]-1-piperidinecarboxylate
4-Amino-5-cyano-6-ethoxy-N-[4-(methylsulfonyl)benzyl]-2-pyridinec arboxamide
C17H18N4O4S (374.10487080000007)
Equilin 3-Sulfate-d4 sodium salt
C18H15D4NaO5S (374.11019311200005)
((2R,3R,4R,5R)-3-(benzoyloxy)-4-fluoro-5-hydroxy-4-methyltetrahydrofuran-2-yl)methyl benzoate
6-deoxy-1,2-O-isopropylidene-6-(4-methylbenzene)sulfonyloxy-D-glucofuranose
(3R,4R)-3-hydroxy-3,4-bis[(4-hydroxy-3-methoxy-phenyl)methyl]oxolan-2- one
(10-([1,1-biphenyl]-3-yl)anthracen-9-yl)boronic acid
6-(difluoro(6-phenyl-[1,2,4]triazolo[4,3-b][1,2,4]triazin-3-yl)Methyl)quinoline
(10-[1,1-Biphenyl]-2-yl-9-anthracenyl)boronic acid
1,3,4-Oxadiazole,2,5-bis([1,1-biphenyl]-4-yl)-
C26H18N2O (374.14190579999996)
17-Beta-Estradiol-3-O-Sulfate Sodium
C18H23NaO5S (374.11638280000005)
17β-Estradiol sulfate (sodium), also known as β-Estradiol 3-sulfate sodium salt, is a neuroactive steroid[1][2].
(10R)-10-methyl-3-(6-methylpyridin-3-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5,6:4,5]thieno[3,2-f]quinolin-8-one
Puromycin aminonucleoside 5-monophosphate
C12H19N6O6P (374.11036440000004)
2-[[3-[(2-phenylacetyl)amino]benzoyl]amino]benzoic Acid
(Z)-7-[(2S,4S,5R)-4-(2-hydroxyphenyl)-2-(trifluoromethyl)-1,3-dioxan-5-yl]hept-5-enoic acid
C18H21F3O5 (374.13410120000003)
3-(Acetyloxy)-9-mercaptoandrosta-3,5-diene-11,17-dione
2-{4-(2-furylmethyl)-5-[(3-phenyl-2-propen-1-yl)thio]-4H-1,2,4-triazol-3-yl}pyridine
1-(1-Benzotriazolyl)-3-(10-phenothiazinyl)-2-propanol
[4-(4-Phenyl-piperidin-1-yl)-benzenesulfonylamino]-acetic acid
C19H22N2O4S (374.13002120000004)
CA042; N-(L-3-trans-Ethoxycarbonyloxirane-2-carbonyl)-L-threonyl-L-isoleucine
436-32-8
Diffractaic acid, a major constituent of U. longissimi, acts as an effective proapoptotic agent in various disorders research[1]. Diffractaic acid is the analgesic and antipyretic component of Usnea diffracta[2]. Diffractaic acid, a major constituent of U. longissimi, acts as an effective proapoptotic agent in various disorders research[1]. Diffractaic acid is the analgesic and antipyretic component of Usnea diffracta[2].
5-N-(1H-benzimidazol-2-yl)-4-N-(2,4-dimethylphenyl)-1H-imidazole-4,5-dicarboxamide
C20H18N6O2 (374.14911679999994)
[2-(2-Acetyloxypropan-2-yl)-7-oxo-2,3-dihydrouro[3,2-g]chromen-3-yl] 2-methylpropanoate
3-hydroxy-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]oxolan-2-one
(4R,4aR)-4-ethenyl-4a-hydroxy-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,4,5,6-tetrahydropyrano[3,4-c]pyran-8-one
2-Chloro-10-[3-(4-methylpiperazin-1-ium-1-yl)propyl]phenothiazine
C20H25ClN3S+ (374.14576200000005)
3,6-bis(1H-indol-3-yl)cyclohexa-2,5-diene-1,2,4,5-tetrol
(1S,4R)-4-[[(3S)-3-hydroxyindol-3-yl]methyl]-1-methyl-2,4-dihydro-1H-pyrazino[2,1-b]quinazoline-3,6-dione
C21H18N4O3 (374.13788379999994)
(4E)-4-[2-[1-carboxy-2-(4-hydroxyphenyl)ethyl]iminoethylidene]-2,3-dihydro-1H-pyridine-2,6-dicarboxylic acid
3-[2-(Cyclohexylamino)-4-(4-methoxyphenyl)-5-thiazolyl]propanoic acid methyl ester
C20H26N2O3S (374.1664046000001)
2-[3-[2-furanyl(oxo)methyl]-1-indolyl]-N-(2-methoxyphenyl)acetamide
(E)-3-[4-[alpha-(Hydroxymethyl)-4,beta-dihydroxy-3-methoxyphenethyloxy]-3-methoxyphenyl]acrylaldehyde
4-phenyl-N-[sulfanylidene-(2,4,6-trimethylanilino)methyl]benzamide
4alpha-Hydroxypinoresinol
A lignan that is pinoresinol substituted by a hydroxy group at position 4. It has been isolated from the roots of Scorzonera judaica.
N-(4-benzamido-3-methylphenyl)-1,3-benzodioxole-5-carboxamide
2-(4-chloro-2-methylphenoxy)-N-[2-(4-morpholinyl)phenyl]propanamide
2-[[5-(2-Furanyl)-4-(2-furanylmethyl)-1,2,4-triazol-3-yl]thio]-1-(4-morpholinyl)ethanone
C17H18N4O4S (374.10487080000007)
N-[2-(trifluoromethyl)-1,3-benzodioxol-2-yl]-1,4-dioxa-8-azaspiro[4.5]decane-8-carboxamide
3-Methyl-benzoic acid 4-[(2-hydroxy-benzoyl)-hydrazonomethyl]-phenyl ester
2-[2-Oxo-2-(2,2,4,6-tetramethyl-1-quinolinyl)ethyl]isoindole-1,3-dione
C23H22N2O3 (374.16303419999997)
4-{4-(2-furylmethyl)-5-[(3-phenyl-2-propen-1-yl)thio]-4H-1,2,4-triazol-3-yl}pyridine
3-[2-(4-chlorophenyl)-4-quinolinyl]-6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepine
C22H19ClN4 (374.12981640000004)
N-[3-[(1,3-dimethyl-2,6-dioxo-4-pyrimidinyl)methylamino]-3-oxopropyl]-3-methoxybenzamide
1-[1-Ethyl-4-[4-(4-fluorophenyl)-1-piperazinyl]-6-methyl-2-sulfanylidene-5-pyrimidinyl]ethanone
4-Acetamidobenzenesulfonic acid [2-(1-piperidinyl)phenyl] ester
C19H22N2O4S (374.13002120000004)
1-(4-Cyanophenyl)-3-[1-[(4-methoxyphenyl)methyl]-2-oxo-3-pyridinyl]urea
C21H18N4O3 (374.13788379999994)
4-[2-(4-Fluorophenyl)-5-phenyl-7-pyrazolo[1,5-a]pyrimidinyl]morpholine
N-(4-ethylphenyl)-2-(2-furanylmethyl)-1,3-dioxo-5-isoindolecarboxamide
N-[2-(1-cyclohexenyl)ethyl]-1-[cyclopropyl(oxo)methyl]-2,3-dihydroindole-5-sulfonamide
C20H26N2O3S (374.1664046000001)
4-[2-[(4-Fluorophenyl)methylamino]-2-oxoethyl]-2-methyl-5-thieno[3,2-b]pyrrolecarboxylic acid ethyl ester
C19H19FN2O3S (374.11003560000006)
4-[(E)-{2-[2-(2-fluorophenyl)quinazolin-4-yl]hydrazinylidene}methyl]benzene-1,3-diol
C21H15FN4O2 (374.11789819999996)
N-[[(2R,3R,4R)-4-(hydroxymethyl)-3-phenyl-2-azetidinyl]methyl]-N-propan-2-ylbenzenesulfonamide
C20H26N2O3S (374.1664046000001)
(E)-7-[4-(2-hydroxyphenyl)-2-(trifluoromethyl)-1,3-dioxan-5-yl]hept-5-enoic acid
C18H21F3O5 (374.13410120000003)
(2S,3R,4S)-4-(hydroxymethyl)-3-[4-(3-methoxyprop-1-ynyl)phenyl]-1-(1-oxo-2-phenylethyl)-2-azetidinecarbonitrile
C23H22N2O3 (374.16303419999997)
(2S,3S,4S)-4-(hydroxymethyl)-3-[4-(3-methoxyprop-1-ynyl)phenyl]-1-(2-phenylacetyl)azetidine-2-carbonitrile
C23H22N2O3 (374.16303419999997)
(2R,3R,4S)-1-ethylsulfonyl-3-[4-(3-fluorophenyl)phenyl]-4-(hydroxymethyl)azetidine-2-carbonitrile
C19H19FN2O3S (374.11003560000006)
(2R,3S,4S)-1-ethylsulfonyl-3-[4-(3-fluorophenyl)phenyl]-4-(hydroxymethyl)-2-azetidinecarbonitrile
C19H19FN2O3S (374.11003560000006)
(2S,3R,4R)-1-ethylsulfonyl-3-[4-(3-fluorophenyl)phenyl]-4-(hydroxymethyl)azetidine-2-carbonitrile
C19H19FN2O3S (374.11003560000006)
(2S,3S,4R)-1-ethylsulfonyl-3-[4-(3-fluorophenyl)phenyl]-4-(hydroxymethyl)-2-azetidinecarbonitrile
C19H19FN2O3S (374.11003560000006)
(2R,3R,4R)-4-(hydroxymethyl)-3-[4-(3-methoxyprop-1-ynyl)phenyl]-1-(1-oxo-2-phenylethyl)-2-azetidinecarbonitrile
C23H22N2O3 (374.16303419999997)
N-[[(2S,3S,4S)-4-(hydroxymethyl)-3-phenyl-2-azetidinyl]methyl]-N-propan-2-ylbenzenesulfonamide
C20H26N2O3S (374.1664046000001)
1-O-(3,4,5-Trimethoxybenzoyl)-beta-L-galactopyranose
7-[2beta-(Trifluoromethyl)-6beta-(2-hydroxyphenyl)-1,3-dioxan-5beta-yl]-5-heptenoic acid
C18H21F3O5 (374.13410120000003)
2-[4,6-Dihydroxy-2-methoxy-3-(3-methylbut-2-enyl)phenyl]-1-(2,4,5-trihydroxyphenyl)ethanone
N-(2-Butoxy-4-quinolinecarbonyl)glycine trimethylsilyl ester
C19H26N2O4Si (374.16617560000003)
Kievitone hydrate
A hydroxyisoflavanone that is isoflavanone substituted by hydroxy groups at positions 5, 7, 2 and 4 and a 3-hydroxy-3-methylbutyl group at position 8.
4-Ethenyl-4a-hydroxy-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,4,5,6-tetrahydropyrano[3,4-c]pyran-8-one
N-[(5-Hydroxy-2-pyridinyl)methyl]adenosine
C16H18N6O5 (374.13386180000003)
7-[4-(2-hydroxyphenyl)-2-(trifluoromethyl)-1,3-dioxan-5-yl]-5-heptenoic acid
C18H21F3O5 (374.13410120000003)
7-[(2S,4S,5R)-4-(2-hydroxyphenyl)-2-(trifluoromethyl)-1,3-dioxan-5-yl]-5-heptenoic acid
C18H21F3O5 (374.13410120000003)
6-CEPN
6-CEPN is a RAS inhibitor. 6-CEPN can inhibit RAS activation by binding to Icmt binding sites. 6-CEPN has anticancer activity. 6-CEPN can block cancer cells in the G1 phase. 6-CEPN can induce autophagy and necrosis of Cancer cells (Icmt: isovalerylcysteine carboxymethyltransferase)[1].
Alniditan (dihydrochloride)
Alniditan (Alnitidan) dihydrochloride is a potent 5-HT1B and 5-HT1D receptors agonist, with IC50s of 1.7 nM and 1.3 nM for h5-HT1B and h5-HT1D receptors in HEK?293 cells, respectively. Alniditan dihydrochloride has migraine-preventive effects[1][2].
RK-9123016
RK-9123016 is a potent inhibitor of SIRT2. RK-9123016 inhibits the enzymatic activity of SIRT2 with an IC50?value of 0.18?μM but not other human sirtuin members including SIRT1 and SIRT3 at 100?μM. RK-9123016 increases the acetylation level of eukaryotic translation initiation factor 5A (eIF5A), a physiological substrate of SIRT2, and reduces cell viability of human breast cancer cells accompanied with a decrease in c-Myc expression[1].