Famoxadone (BioDeep_00000012330)

   

Industrial Pollutants


代谢物信息卡片


3-Anilino-5-methyl-5-(3-phenoxyphenyl)-1,3-oxazolidine-2,4-dione

化学式: C22H18N2O4 (374.1267)
中文名称: 恶唑酮菌, 法莫沙酮
谱图信息: 最多检出来源 Homo sapiens(not specific) 5.26%

分子结构信息

SMILES: CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC(=CC=C3)OC4=CC=CC=C4
InChI: InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3

描述信息

D010575 - Pesticides > D005659 - Fungicides, Industrial > D000073739 - Strobilurins
CONFIDENCE standard compound; INTERNAL_ID 403; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5208; ORIGINAL_PRECURSOR_SCAN_NO 5203
CONFIDENCE standard compound; INTERNAL_ID 403; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5187; ORIGINAL_PRECURSOR_SCAN_NO 5183
CONFIDENCE standard compound; INTERNAL_ID 403; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5271; ORIGINAL_PRECURSOR_SCAN_NO 5269
CONFIDENCE standard compound; INTERNAL_ID 403; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5195; ORIGINAL_PRECURSOR_SCAN_NO 5192
CONFIDENCE standard compound; EAWAG_UCHEM_ID 3049

同义名列表

5 个代谢物同义名

Famoxadone; 3-Anilino-5-methyl-5-(3-phenoxyphenyl)-1,3-oxazolidine-2,4-dione; SCHEMBL7761159; FMD; Famoxadone



数据库引用编号

23 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Jianqiang Miao, Xuheng Gao, Yidong Tang, Tan Dai, Xili Liu. Characteristics of famoxadone-resistant mutants of Phytophthora litchii and their effect on lychee fruit quality. International journal of food microbiology. 2024 Feb; 411(?):110528. doi: 10.1016/j.ijfoodmicro.2023.110528. [PMID: 38118356]
  • Luwei Li, Deyou Yang, Heng Li, Guangyou Chen, Peng Lei, Yanqing Gao, Juntao Feng. Heterocycle-Substituted α-Methylene-γ-Butyrolactones Derivatives Synthesis, Antifungal Activity, and 3D-QSAR. Journal of agricultural and food chemistry. 2023 Jul; ?(?):. doi: 10.1021/acs.jafc.3c02117. [PMID: 37432089]
  • Xiaoxiao Feng, Guoxin Liu, Xinyue Wang, Kai An, Yajing Guo, Yingchao Liu, Jingao Dong. Uptake, Translocation, and Subcellular Distribution of Oxathiapiprolin and Famoxadone in Tomato Plants (Lycopersicon esculentum Miller). Journal of agricultural and food chemistry. 2022 Oct; 70(39):12310-12319. doi: 10.1021/acs.jafc.2c03668. [PMID: 36134436]
  • Guofeng Xu, Xiaohui Jia, Chi Wu, Xingang Liu, Fengshou Dong. Chiral Fungicide Famoxadone: Stereoselective Bioactivity, Aquatic Toxicity, and Environmental Behavior in Soils. Journal of agricultural and food chemistry. 2021 Aug; 69(30):8530-8535. doi: 10.1021/acs.jafc.1c00825. [PMID: 34313440]
  • Meng Wang, Zerong Ji, Jiabin Xu, Chenghui Zhang, Ye Yang, Xiaoyu Liang, Yu Zhang. Study on stereoselective bioactivity, acute toxicity, and degradation in cucurbits and soil of chiral fungicide famoxadone. Environmental science and pollution research international. 2021 Apr; 28(13):15947-15953. doi: 10.1007/s11356-020-11810-z. [PMID: 33245543]
  • Rosalía López-Ruiz, Roberto Romero-González, Antonia Garrido Frenich. Residues and dissipation kinetics of famoxadone and its metabolites in environmental water and soil samples under different conditions. Environmental pollution (Barking, Essex : 1987). 2019 Sep; 252(Pt A):163-170. doi: 10.1016/j.envpol.2019.05.123. [PMID: 31146231]
  • Xiaoxiao Feng, Lixiang Pan, Tianheng Xu, Jing Jing, Hongyan Zhang. Dynamic modeling of famoxadone and oxathiapiprolin residue on cucumber and Chinese cabbage based on tomato and lettuce archetypes. Journal of hazardous materials. 2019 Aug; 375(?):70-77. doi: 10.1016/j.jhazmat.2019.04.075. [PMID: 31048137]
  • Guofeng Xu, Xiaohui Jia, Xiaohu Wu, Jun Xu, Xingang Liu, Xinglu Pan, Runan Li, Xinghai Li, Fengshou Dong. Enantioselective monitoring of chiral fungicide famoxadone enantiomers in tomato, apple, and grape by chiral liquid chromatography with tandem mass spectrometry. Journal of separation science. 2018 Oct; 41(20):3871-3880. doi: 10.1002/jssc.201800681. [PMID: 30136372]
  • Dicheng Ma, Jiangong Jiang, Leiming He, Kaidi Cui, Wei Mu, Feng Liu. Detection and Characterization of QoI-Resistant Phytophthora capsici Causing Pepper Phytophthora Blight in China. Plant disease. 2018 Sep; 102(9):1725-1732. doi: 10.1094/pdis-01-18-0197-re. [PMID: 30125205]
  • Xiaoxiao Feng, Kai Wang, Lixiang Pan, Tianheng Xu, Hongyan Zhang, Peter Fantke. Measured and Modeled Residue Dynamics of Famoxadone and Oxathiapiprolin in Tomato Fields. Journal of agricultural and food chemistry. 2018 Aug; 66(32):8489-8495. doi: 10.1021/acs.jafc.8b02056. [PMID: 30028951]
  • George Balayiannis, Helen Karasali, Arpad Ambrus. Rapid determination of famoxadone and cymoxanil in commercial pesticide formulation by high performance liquid chromatography using a C18 monolithic rod column. Bulletin of environmental contamination and toxicology. 2014 Dec; 93(6):775-80. doi: 10.1007/s00128-014-1382-7. [PMID: 25236328]
  • Pedro Albuquerque, Cristina M R Caridade, Arlete S Rodrigues, Andre R S Marcal, Joana Cruz, Leonor Cruz, Catarina L Santos, Marta V Mendes, Fernando Tavares. Evolutionary and experimental assessment of novel markers for detection of Xanthomonas euvesicatoria in plant samples. PloS one. 2012; 7(5):e37836. doi: 10.1371/journal.pone.0037836. [PMID: 22655073]
  • Congyun Liu, Dongmei Qin, Yuzhen Zhao, Canping Pan, Shuren Jiang, Fengmao Liu. Famoxadone residue and dissipation in watermelon and soil. Ecotoxicology and environmental safety. 2010 Feb; 73(2):183-8. doi: 10.1016/j.ecoenv.2009.08.003. [PMID: 19836076]
  • Wei-Jen Chen, François Delmotte, Sylvie Richard-Cervera, Lisette Douence, Charles Greif, Marie-France Corio-Costet. At least two origins of fungicide resistance in grapevine downy mildew populations. Applied and environmental microbiology. 2007 Aug; 73(16):5162-72. doi: 10.1128/aem.00507-07. [PMID: 17586672]
  • D T Likas, N G Tsiropoulos, G E Miliadis. Rapid gas chromatographic method for the determination of famoxadone, trifloxystrobin and fenhexamid residues in tomato, grape and wine samples. Journal of chromatography. A. 2007 May; 1150(1-2):208-14. doi: 10.1016/j.chroma.2006.08.041. [PMID: 16950327]
  • Jean-Luc Genet, Grazyna Jaworska, Francine Deparis. Effect of dose rate and mixtures of fungicides on selection for QoI resistance in populations of Plasmopara viticola. Pest management science. 2006 Feb; 62(2):188-94. doi: 10.1002/ps.1146. [PMID: 16411165]
  • Stephen O Pember, Lois C Fleck, William K Moberg, Michael P Walker. Mechanistic differences in inhibition of ubiquinol cytochrome c reductase by the proximal Qo-site inhibitors famoxadone and methoxyacrylate stilbene. Archives of biochemistry and biophysics. 2005 Mar; 435(2):280-90. doi: 10.1016/j.abb.2004.12.013. [PMID: 15708371]
  • U Steinfeld, H Sierotzki, S Parisi, S Poirey, U Gisi. Sensitivity of mitochondrial respiration to different inhibitors in Venturia inaequalis. Pest management science. 2001 Sep; 57(9):787-96. doi: 10.1002/ps.356. [PMID: 11561403]
  • J A Sternberg, D Geffken, J B Adams, R Pöstages, C G Sternberg, C L Campbell, W K Moberg. Famoxadone: the discovery and optimisation of a new agricultural fungicide. Pest management science. 2001 Feb; 57(2):143-52. doi: 10.1002/1526-4998(200102)57:2<143::aid-ps282>3.0.co;2-8. [PMID: 11455645]
  • D Geffken. [University-based research application: the plant disease drug famoxadon (Famoxate)]. Pharmazie in unserer Zeit. 1999 Sep; 28(5):240-6. doi: ". [PMID: 10546494]
  • D B Jordan, K T Kranis, M A Picollelli, R S Schwartz, J A Sternberg, K M Sun. Famoxadone and oxazolidinones: potent inhibitors of cytochrome bc1. Biochemical Society transactions. 1999 Aug; 27(4):577-80. doi: 10.1042/bst0270577. [PMID: 10917645]