Exact Mass: 353.9513472
Exact Mass Matches: 353.9513472
Found 60 metabolites which its exact mass value is equals to given mass value 353.9513472,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Pipobroman
Pipobroman is only found in individuals that have used or taken this drug. It is an antineoplastic agent that acts by alkylation. [PubChem]The mechanism of action is uncertain but pipobroman is thought to alkylate DNA leading to disruption of DNA synthesis and eventual cell death. L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01A - Alkylating agents C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C2842 - DNA Binding Agent D009676 - Noxae > D000477 - Alkylating Agents D000970 - Antineoplastic Agents
idoxuridine
J - Antiinfectives for systemic use > J05 - Antivirals for systemic use > J05A - Direct acting antivirals > J05AB - Nucleosides and nucleotides excl. reverse transcriptase inhibitors D - Dermatologicals > D06 - Antibiotics and chemotherapeutics for dermatological use > D06B - Chemotherapeutics for topical use > D06BB - Antivirals S - Sensory organs > S01 - Ophthalmologicals > S01A - Antiinfectives > S01AD - Antivirals D004791 - Enzyme Inhibitors > D019384 - Nucleic Acid Synthesis Inhibitors D000890 - Anti-Infective Agents > D000998 - Antiviral Agents C274 - Antineoplastic Agent > C798 - Radiosensitizing Agent Idoxuridine (5-Iodo-2′-deoxyuridine, 5-IUdR, IdUrd) is an iodinated thymidine analogue that competitively inhibits phosphorylases. Idoxuridine can inhibit viral activity, particularly viral eye infections, including herpes simplex keratitis, by inhibiting DNA polymerase and affecting viral replication. Idoxuridine against feline herpesvirus has the IC50 value of 4.3 μM[1]. Idoxuridine shows anti-orthopoxvirus activity.
Idoxuridine
Idoxuridine is only found in individuals that have used or taken this drug. It is an analog of deoxyuridine that inhibits viral DNA synthesis. The drug is used as an antiviral agent. [PubChem]Idoxuridine acts as an antiviral agent by inhibiting viral replication by substituting itself for thymidine in viral DNA. This in turn inhibits thymidylate phosphorylase and viral DNA polymerases from properly functioning. The effect of Idoxuridine results in the inability of the virus to reproduce or to infect/destroy tissue. J - Antiinfectives for systemic use > J05 - Antivirals for systemic use > J05A - Direct acting antivirals > J05AB - Nucleosides and nucleotides excl. reverse transcriptase inhibitors D - Dermatologicals > D06 - Antibiotics and chemotherapeutics for dermatological use > D06B - Chemotherapeutics for topical use > D06BB - Antivirals S - Sensory organs > S01 - Ophthalmologicals > S01A - Antiinfectives > S01AD - Antivirals D004791 - Enzyme Inhibitors > D019384 - Nucleic Acid Synthesis Inhibitors D000890 - Anti-Infective Agents > D000998 - Antiviral Agents C274 - Antineoplastic Agent > C798 - Radiosensitizing Agent Idoxuridine (5-Iodo-2′-deoxyuridine, 5-IUdR, IdUrd) is an iodinated thymidine analogue that competitively inhibits phosphorylases. Idoxuridine can inhibit viral activity, particularly viral eye infections, including herpes simplex keratitis, by inhibiting DNA polymerase and affecting viral replication. Idoxuridine against feline herpesvirus has the IC50 value of 4.3 μM[1]. Idoxuridine shows anti-orthopoxvirus activity.
5'-Iododeoxyuridine
Diphosphoglucuronic acid
(2S,4R,5S)-4,5,6-Trihydroxy-2-[hydroxy(phosphonooxy)phosphoryl]oxy-3-oxohexanoic acid
Carbamic acid, (2-chloro-3-iodo-4-pyridinyl)-, 1,1-dimethylethyl ester (9CI)
C10H12ClIN2O2 (353.96320319999995)
Tungsten,tricarbonyl[(1,2,3,4,5,6-h)-1,3,5-cycloheptatriene]-
4,5-diamino-2-(4-bromo-2-chloroanilino)-3-fluorobenzonitrile
1-chloro-1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluorohexane
3-(4-BROMO-2-CHLOROPHENOXYMETHYL)-4-METHOXYBENZALDEHYDE
C15H12BrClO3 (353.96582920000003)
7-bromo-5-(2-chlorophenyl)-1,3-dihydro-2H-thieno(2,3-e)(1,4)diazepin-2-one
C13H8BrClN2OS (353.92292080000004)
5-Bromo-2-Chloro-N-[2-(Ethylamino)-3-Pyridinyl]-3-Pyridinecarboxamide
(6-bromonaphthalen-2-yl) trifluoromethanesulfonate
C11H6BrF3O3S (353.9173102000001)
ethyl 3-(2,3-difluoro-5-iodophenyl)-3-oxopropanoate
tert-Butyl (6-chloro-4-iodopyridin-3-yl)carbamate
C10H12ClIN2O2 (353.96320319999995)
tert-butyl N-(2-chloro-4-iodopyridin-3-yl)carbamate
C10H12ClIN2O2 (353.96320319999995)
1-(2-bromo-4,5-difluorobenzenesulfonyl)-4-methylpiperazine
Cyclopentadienyliron Dicarbonyl Dimer
C14H10Fe2O4 (353.92778400000003)
(3-Bromo-2-((2-chlorobenzyl)oxy)-5-methylphenyl)boronic acid
(3-Bromo-2-((4-chlorobenzyl)oxy)-5-methylphenyl)boronic acid
(3-Bromo-2-((3-chlorobenzyl)oxy)-5-methylphenyl)boronic acid
3-(2-BROMO-4-CHLOROPHENOXYMETHYL)-4-METHOXYBENZALDEHYDE
C15H12BrClO3 (353.96582920000003)
(4-BROMO-2,6-DICHLOROPHENOXY)(TERT-BUTYL)DIMETHYLSILANE
C12H17BrCl2OSi (353.96090319999996)
5-Deoxy-5-iodouridine
5'-Deoxy-5'-iodouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Uridine, 2-deoxy-5-iodo-
D004791 - Enzyme Inhibitors > D019384 - Nucleic Acid Synthesis Inhibitors D000890 - Anti-Infective Agents > D000998 - Antiviral Agents
2-[(2,6-Dichlorophenyl)methylsulfanyl]-5-pyrazin-2-yl-1,3,4-thiadiazole
Yoda 1 is a potent and selective Piezo1 agonist. Yoda 1 activates purified Piezo1 channels. Yoda 1 potently inhibits macropinocytosis induced by epidermal growth factor (EGF). Yoda 1 enhances Ca2+ influx followed by activation of the calcium-activated potassium channel KCa3.1 and inhibition of Rac1 activation[1][2][3].
2,4-Dihydroxy-3-oxo-5-phosphonooxy-2-(phosphonooxymethyl)pentanoic acid
2,3,4-Trihydroxy-5-[hydroxy(phosphonooxy)phosphoryl]oxy-6-oxohexanoic acid
(2S,4R,5S)-4,5,6-Trihydroxy-2-[hydroxy(phosphonooxy)phosphoryl]oxy-3-oxohexanoic acid
3-[[(2,4-Dichloroanilino)-sulfanylidenemethyl]amino]-4-methylbenzoic acid
2-[(E)-2-(3-bromophenyl)ethenyl]-8-nitroquinoline
C17H11BrN2O2 (354.00038459999996)
5-bromo-N-[(E)-(5-nitrothiophen-2-yl)methylidene]pyridine-3-carbohydrazide
C11H7BrN4O3S (353.94222120000006)
pipobroman
L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01A - Alkylating agents C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C2842 - DNA Binding Agent D009676 - Noxae > D000477 - Alkylating Agents D000970 - Antineoplastic Agents
1-[(2R,5R)-4-hydroxy-5-(hydroxymethyl)-2-oxolanyl]-5-iodopyrimidine-2,4-dione
5-BDBD
C17H11BrN2O2 (354.00038459999996)
5-BDBD, a potent and selective P2X4 receptor antagonist, inhibits rP2X4R-mediated currents, with an IC50 of 0.75 μM. 5-BDBD completely blocks the basal and acute hyperalgesia induced by nitroglycerin (NTG)[1][2].