Exact Mass: 331.00448040000003
Exact Mass Matches: 331.00448040000003
Found 86 metabolites which its exact mass value is equals to given mass value 331.00448040000003,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Hydroflumethiazide
Hydroflumethiazide is only found in individuals that have used or taken this drug. It is a thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p822)Hydroflumethiazide is a thiazide diuretic that inhibits water reabsorption in the nephron by inhibiting the sodium-chloride symporter (SLC12A3) in the distal convoluted tubule, which is responsible for 5\\% of total sodium reabsorption. Normally, the sodium-chloride symporter transports sodium and chloride from the lumen into the epithelial cell lining the distal convoluted tubule. The energy for this is provided by a sodium gradient established by sodium-potassium ATPases on the basolateral membrane. Once sodium has entered the cell, it is transported out into the basolateral interstitium via the sodium-potassium ATPase, causing an increase in the osmolarity of the interstitium, thereby establishing an osmotic gradient for water reabsorption. By blocking the sodium-chloride symporter, Hydroflumethiazide effectively reduces the osmotic gradient and water reabsorption throughout the nephron. C - Cardiovascular system > C03 - Diuretics > C03A - Low-ceiling diuretics, thiazides > C03AA - Thiazides, plain D045283 - Natriuretic Agents > D004232 - Diuretics > D049993 - Sodium Chloride Symporter Inhibitors C78275 - Agent Affecting Blood or Body Fluid > C448 - Diuretic > C49185 - Thiazide Diuretic D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents D002317 - Cardiovascular Agents > D045283 - Natriuretic Agents D049990 - Membrane Transport Modulators
8-Hydroxyefavirenz
C14H9ClF3NO3 (331.02230299999997)
7-Hydroxyefavirenz
C14H9ClF3NO3 (331.02230299999997)
N-{4-[1-Cyano-2-(3,4-dichlorophenyl)vinyl]phenyl}urea
C16H11Cl2N3O (331.02791360000003)
2-(Methylsulfonyl)-3-(6-phenyl-2,3-dihydroimidazo[2,1-b][1,3]thiazol-5-yl)acrylonitrile
N-(2,4-Dinitrophenyl)-DL-methionine sulfoxide
C11H13N3O7S (331.04741880000006)
[5-chloro-2-[3-(chloromethyl)-4H-1,2,4-triazol-4-yl]phenyl] phenyl ketone
C16H11Cl2N3O (331.02791360000003)
3-(trifluoromethyl)phenyltrimethylammonium iodide
C10H13F3IN (331.00448040000003)
4-(4-chloro-3-methylphenoxy)-3-nitrobenzotrifluoride
C14H9ClF3NO3 (331.02230299999997)
2-CHLORO-N-{4-[(1,3-THIAZOL-2-YLAMINO)SULFONYL]PHENYL}ACETAMIDE
6-BROMO-2-(5-METHYL-FURAN-2-YL)QUINOLINE-4-CARBOXYLICACID
C15H10BrNO3 (330.98440100000005)
3-Propeneamido-1-(2,4,6-trichlorophenyl)-5-pyrazolone
Dimethyl 2-(4-(methylsulfonyl)-2-nitrophenyl)malonate
C12H13NO8S (331.03618580000006)
TERT-BUTYL 5-BROMO-4-CHLORO-7H-PYRROLO[2,3-D]PYRIMIDINE-7-CARBOXYLATE
5-chloro-4-(1,3-dioxoisoindol-2-yl)-2-methoxybenzoic acid
5-nitro-1,10-phenanthroline-2,9-dicarboxylic acid
C14H9N3O7 (331.04404839999995)
methyl 3-(cyclopropylamino)-2-(2,4-dichloro-5-fluorobenzoyl)acrylate
3-Benzyl-6-bromo-2-chloroquinoline
C16H11BrClN (330.97633360000003)
2-[2-[4-(2-methyl-1,3-thiazol-4-yl)anilino]-1,3-thiazol-4-yl]acetic acid
4-Bromo-1,2,3,4-tetrahydro-1-[(4-methylphenyl)sulfonyl]-5H-1-benzazepin-5-one
C10H13Cl3NO3P (330.96986080000005)
5-Iodopyridine-3-boronic acid pinacol ester
C11H15BINO2 (331.02405500000003)
1-cyclopropyl-8-(difluoromethoxy)-6,7-difluoro-4-oxoquinoline-3-carboxylic acid
C14H9F4NO4 (331.04676820000003)
2-BROMO-6-CHLORO-N-(2,6-DIMETHYLPHENYL)HEXANOYLAMIDE
1-[2-(4-iodophenoxy)ethyl]piperidine
C13H18INO (331.04330880000003)
2-(2,3,3-trimethylindol-1-ium-1-yl)ethanol,iodide
C13H18INO (331.04330880000003)
METHYL 3-AMINO-4-[(4-CHLOROPHENYL)SULFONYL]THIOPHENE-2-CARBOXYLATE
2-methylbenzofuro[2,3-b]pyridin-8-yl trifluoromethanesulfonate
N-(3-CHLOROPHENYL)-2-(5-(3-FLUOROPHENYL)-1,2,4-OXADIAZOL-3-YL)ACETAMIDE
1-Benzyl-3-bromo-5-(trifluoromethyl)pyridin-2(1H)-one
2-[[(4-CHLOROPHENYL)SULFONYL]METHYL]-1,3-THIAZOLE-4-CARBOHYDRAZIDE
4-[(4-Phenyl-2-thiazolyl)amino]-benzenesulfonamide
(5Z)-5-[[4-(2-thiophen-2-ylethoxy)phenyl]methylidene]-1,3-thiazolidine-2,4-dione
N-(4-fluoro-3-methyl-1,3-benzothiazol-2-ylidene)-2-nitrobenzamide
C15H10FN3O3S (331.04268820000004)
2,7,9-Tricarboxypyrrolo(2,3-f)quinoline-4-ol-5-one
2-[(2-Naphthylsulfonyl)amino]ethyl dihydrogen phosphate
C12H14NO6PS (331.0279434000001)
Laricitrin(1-)
The conjugate base of laricitrin arising from deprotonation of the 3-OH group; major species at pH 7.3.
2-(3,4-Dihydroxyphenyl)-3,7-dihydroxy-6-methoxy-4-oxochromen-5-olate
L-glycero-L-galacto-octuluronate-1-phosphate
C8H12O12P-3 (331.00663820000005)
alpha-L-glycero-L-galacto-octulonopyranose 1-phosphate
C8H12O12P-3 (331.00663820000005)
7-Imino-5-methyl-3-sulfonatophenazine-1-carboxylate
N-(4-bromo-3-methylphenyl)-2,5-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
C14H14BrN5 (331.04325040000003)
N-[4-(3-methoxyphenyl)-2-thiazolyl]-2-thiophenecarbohydrazide
4-Thiomorpholinecarbodithioic acid [2-(4-chlorophenyl)-2-oxoethyl] ester
2-[2-(4-Methoxyphenyl)-2-oxoethyl]-1,1-dioxo-1,2-benzothiazol-3-one
2-(3-thiophenyl)acetic acid [2-oxo-2-(3-oxo-4H-1,4-benzoxazin-6-yl)ethyl] ester
N-[2-(1,3-benzothiazol-2-ylthio)-1-oxoethyl]-1-methyl-2-pyrrolecarboxamide
5-bromo-2-spiro[1,2-dihydro-4,1,2-benzoxadiazine-3,3-1H-indole]one
hydroflumethiazide
C - Cardiovascular system > C03 - Diuretics > C03A - Low-ceiling diuretics, thiazides > C03AA - Thiazides, plain D045283 - Natriuretic Agents > D004232 - Diuretics > D049993 - Sodium Chloride Symporter Inhibitors C78275 - Agent Affecting Blood or Body Fluid > C448 - Diuretic > C49185 - Thiazide Diuretic D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents D002317 - Cardiovascular Agents > D045283 - Natriuretic Agents D049990 - Membrane Transport Modulators