Exact Mass: 330.9682078
Exact Mass Matches: 330.9682078
Found 45 metabolites which its exact mass value is equals to given mass value 330.9682078,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Hydroflumethiazide
Hydroflumethiazide is only found in individuals that have used or taken this drug. It is a thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p822)Hydroflumethiazide is a thiazide diuretic that inhibits water reabsorption in the nephron by inhibiting the sodium-chloride symporter (SLC12A3) in the distal convoluted tubule, which is responsible for 5\\% of total sodium reabsorption. Normally, the sodium-chloride symporter transports sodium and chloride from the lumen into the epithelial cell lining the distal convoluted tubule. The energy for this is provided by a sodium gradient established by sodium-potassium ATPases on the basolateral membrane. Once sodium has entered the cell, it is transported out into the basolateral interstitium via the sodium-potassium ATPase, causing an increase in the osmolarity of the interstitium, thereby establishing an osmotic gradient for water reabsorption. By blocking the sodium-chloride symporter, Hydroflumethiazide effectively reduces the osmotic gradient and water reabsorption throughout the nephron. C - Cardiovascular system > C03 - Diuretics > C03A - Low-ceiling diuretics, thiazides > C03AA - Thiazides, plain D045283 - Natriuretic Agents > D004232 - Diuretics > D049993 - Sodium Chloride Symporter Inhibitors C78275 - Agent Affecting Blood or Body Fluid > C448 - Diuretic > C49185 - Thiazide Diuretic D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents D002317 - Cardiovascular Agents > D045283 - Natriuretic Agents D049990 - Membrane Transport Modulators
3-(trifluoromethyl)phenyltrimethylammonium iodide
C10H13F3IN (331.00448040000003)
2-CHLORO-N-{4-[(1,3-THIAZOL-2-YLAMINO)SULFONYL]PHENYL}ACETAMIDE
6-BROMO-2-(5-METHYL-FURAN-2-YL)QUINOLINE-4-CARBOXYLICACID
C15H10BrNO3 (330.98440100000005)
3-Propeneamido-1-(2,4,6-trichlorophenyl)-5-pyrazolone
TERT-BUTYL 5-BROMO-4-CHLORO-7H-PYRROLO[2,3-D]PYRIMIDINE-7-CARBOXYLATE
methyl 3-(cyclopropylamino)-2-(2,4-dichloro-5-fluorobenzoyl)acrylate
3-Benzyl-6-bromo-2-chloroquinoline
C16H11BrClN (330.97633360000003)
4-Bromo-1,2,3,4-tetrahydro-1-[(4-methylphenyl)sulfonyl]-5H-1-benzazepin-5-one
C10H13Cl3NO3P (330.96986080000005)
3-Bromo-N-ethyl-5-(trifluoromethyl)benzenesulfonamide
C9H9BrF3NO2S (330.94894300000004)
4-Bromo-N,N-dimethyl-3-(trifluoromethyl)benzenesulfonamide
C9H9BrF3NO2S (330.94894300000004)
METHYL 3-AMINO-4-[(4-CHLOROPHENYL)SULFONYL]THIOPHENE-2-CARBOXYLATE
2-methylbenzofuro[2,3-b]pyridin-8-yl trifluoromethanesulfonate
3-Bromo-N,N-dimethyl-5-(trifluoromethyl)benzenesulfonamide
C9H9BrF3NO2S (330.94894300000004)
1-Benzyl-3-bromo-5-(trifluoromethyl)pyridin-2(1H)-one
4-Bromo-N-ethyl-3-(trifluoromethyl)benzenesulfonamide
C9H9BrF3NO2S (330.94894300000004)
2-[[(4-CHLOROPHENYL)SULFONYL]METHYL]-1,3-THIAZOLE-4-CARBOHYDRAZIDE
L-glycero-L-galacto-octuluronate-1-phosphate
C8H12O12P-3 (331.00663820000005)
alpha-L-glycero-L-galacto-octulonopyranose 1-phosphate
C8H12O12P-3 (331.00663820000005)
4-Thiomorpholinecarbodithioic acid [2-(4-chlorophenyl)-2-oxoethyl] ester
5-bromo-2-spiro[1,2-dihydro-4,1,2-benzoxadiazine-3,3-1H-indole]one
hydroflumethiazide
C - Cardiovascular system > C03 - Diuretics > C03A - Low-ceiling diuretics, thiazides > C03AA - Thiazides, plain D045283 - Natriuretic Agents > D004232 - Diuretics > D049993 - Sodium Chloride Symporter Inhibitors C78275 - Agent Affecting Blood or Body Fluid > C448 - Diuretic > C49185 - Thiazide Diuretic D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents D002317 - Cardiovascular Agents > D045283 - Natriuretic Agents D049990 - Membrane Transport Modulators