Chlozolinate (BioDeep_00000008429)

 

Secondary id: BioDeep_00001874309

human metabolite blood metabolite


代谢物信息卡片


Ethyl 3-(3,5-dichlorophenyl)-5-methyl-2,4-dioxo-1,3-oxazolidine-5-carboxylic acid

化学式: C13H11Cl2NO5 (331.0014256)
中文名称: 乙菌利
谱图信息: 最多检出来源 Homo sapiens(blood) 99.37%

分子结构信息

SMILES: CCOC(=O)C1(C(=O)N(C(=O)O1)C2=CC(=CC(=C2)Cl)Cl)C
InChI: InChI=1S/C13H11Cl2NO5/c1-3-20-11(18)13(2)10(17)16(12(19)21-13)9-5-7(14)4-8(15)6-9/h4-6H,3H2,1-2H3

描述信息

同义名列表

5 个代谢物同义名

Ethyl 3-(3,5-dichlorophenyl)-5-methyl-2,4-dioxo-1,3-oxazolidine-5-carboxylic acid; ethyl 3-(3,5-dichlorophenyl)-5-methyl-2,4-dioxo-1,3-oxazolidine-5-carboxylate; Dichlozolinic acid; Dichlozolinate; CHLOZOLINATE



数据库引用编号

12 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Tanja Krüger, Philip S Hjelmborg, Bo A G Jönsson, Lars Hagmar, Aleksander Giwercman, Gian-Carlo Manicardi, Davide Bizzaro, Marcello Spanò, Anna Rignell-Hydbom, Henning S Pedersen, Gunnar Toft, Jens Peter Bonde, Eva C Bonefeld-Jørgensen. Xenoandrogenic activity in serum differs across European and Inuit populations. Environmental health perspectives. 2007 Dec; 115 Suppl 1(?):21-7. doi: 10.1289/ehp.9353. [PMID: 18174946]
  • Ida N Damgaard, Niels E Skakkebaek, Jorma Toppari, Helena E Virtanen, Heqing Shen, Karl-Werner Schramm, Jørgen H Petersen, Tina K Jensen, Katharina M Main. Persistent pesticides in human breast milk and cryptorchidism. Environmental health perspectives. 2006 Jul; 114(7):1133-8. doi: 10.1289/ehp.8741. [PMID: 16835070]
  • Ann L Wozniak, Nataliya N Bulayeva, Cheryl S Watson. Xenoestrogens at picomolar to nanomolar concentrations trigger membrane estrogen receptor-alpha-mediated Ca2+ fluxes and prolactin release in GH3/B6 pituitary tumor cells. Environmental health perspectives. 2005 Apr; 113(4):431-9. doi: 10.1289/ehp.7505. [PMID: 15811834]
  • Alberto Angioni, Andrea Barra, Marco Arlorio, Jean Daniel Coisson, Maria T Russo, Filippo M Pirisi, Maurizio Satta, Paolo Cabras. Chemical composition, plant genetic differences, and antifungal activity of the essential oil of Helichrysum italicum G. Don ssp. microphyllum (Willd) Nym. Journal of agricultural and food chemistry. 2003 Feb; 51(4):1030-4. doi: 10.1021/jf025940c. [PMID: 12568568]
  • K Wittke, H Hajimiragha, L Dunemann, J Begerow. Determination of dichloroanilines in human urine by GC-MS, GC-MS-MS, and GC-ECD as markers of low-level pesticide exposure. Journal of chromatography. B, Biomedical sciences and applications. 2001 May; 755(1-2):215-28. doi: 10.1016/s0378-4347(01)00078-0. [PMID: 11393707]
  • M A Valentovic, B A Rogers, M K Meadows, J T Conner, E Williams, S K Hong, G O Rankin. Characterization of methemoglobin formation induced by 3,5-dichloroaniline, 4-amino-2,6-dichlorophenol and 3,5-dichlorophenylhydroxylamine. Toxicology. 1997 Mar; 118(1):23-36. doi: 10.1016/s0300-483x(96)03587-1. [PMID: 9074651]
  • M A Valentovic, H H Lo, P I Brown, G O Rankin. 3,5-Dichloroaniline toxicity in Fischer 344 rats pretreated with inhibitors and inducers of cytochrome P450. Toxicology letters. 1995 Aug; 78(3):207-14. doi: 10.1016/0378-4274(95)03249-k. [PMID: 7624891]
  • H H Lo, M A Valentovic, P I Brown, G O Rankin. Effect of chemical form, route of administration and vehicle on 3,5-dichloroaniline-induced nephrotoxicity in the Fischer 344 rat. Journal of applied toxicology : JAT. 1994 Nov; 14(6):417-22. doi: 10.1002/jat.2550140606. [PMID: 7884146]
  • H H Lo, P I Brown, G O Rankin. Acute nephrotoxicity induced by isomeric dichloroanilines in Fischer 344 rats. Toxicology. 1990 Aug; 63(2):215-31. doi: 10.1016/0300-483x(90)90044-h. [PMID: 2399536]
  • G O Rankin, D J Yang, V J Teets, H H Lo, P I Brown. 3,5-Dichloroaniline-induced nephrotoxicity in the Sprague-Dawley rat. Toxicology letters. 1986 Feb; 30(2):173-9. doi: 10.1016/0378-4274(86)90100-1. [PMID: 3705103]