Exact Mass: 288.9901056
Exact Mass Matches: 288.9901056
Found 121 metabolites which its exact mass value is equals to given mass value 288.9901056,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Quinethazone
Quinethazone is only found in individuals that have used or taken this drug. It is a thiazide diuretic used to treat hypertension. Common side effects include dizziness, dry mouth, nausea, and low potassium levels.As a diuretic, quinethazone inhibits active chloride reabsorption at the early distal tubule via the Na-Cl cotransporter, resulting in an increase in the excretion of sodium, chloride, and water. Thiazides like quinethazone also inhibit sodium ion transport across the renal tubular epithelium through binding to the thiazide sensitive sodium-chloride transporter. This results in an increase in potassium excretion via the sodium-potassium exchange mechanism. The antihypertensive mechanism of quinethazone is less well understood although it may be mediated through its action on carbonic anhydrases in the smooth muscle or through its action on the large-conductance calcium-activated potassium (KCa) channel, also found in the smooth muscle. C - Cardiovascular system > C03 - Diuretics > C03B - Low-ceiling diuretics, excl. thiazides > C03BA - Sulfonamides, plain D045283 - Natriuretic Agents > D004232 - Diuretics > D049993 - Sodium Chloride Symporter Inhibitors C78275 - Agent Affecting Blood or Body Fluid > C448 - Diuretic > C49185 - Thiazide Diuretic D002317 - Cardiovascular Agents > D045283 - Natriuretic Agents D049990 - Membrane Transport Modulators
Tillmans Reagent
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents
(4-Methoxyphenyl)-morpholin-4-yl-sulfanyl-sulfanylidene-$l^{5}-phosphane
2-(4-chlorophenyl)-3-phenyl-1,3-thiazolidin-4-one
C15H12ClNOS (289.03280920000003)
2-[2,6-Bis(methylsulfinyl)-4-hydroxyphenyl]diazenecarboxamide
(-)-8S-3-bromo-5-hydroxy-4-methoxyphenylalanine|2-amino-3-(3-bromo-5-hydroxy-4-methoxyphenyl)propanoic acid
C10H12BrNO4 (288.99496519999997)
2-AMINO-4-[2-CHLORO-5-(TRIFLUOROMETHYL)PHENYLAMINO]-1,3,5-TRIAZINE 98
6-Bromo-2-methanesulfonyl-1,2,3,4-tetrahydroisoquinoline
2-Nitro-4-(trifluoromethyl)benzenesulfonyl chloride
C7H3ClF3NO4S (288.94234240000003)
TERT-BUTYL 2,4-DICHLORO-5H-PYRROLO[3,4-D]PYRIMIDINE-6(7H)-CARBOXYLATE
5-BROMO-N-(TERT-BUTYL)-2-CHLOROBENZAMIDE
C11H13BrClNO (288.98689780000007)
3-AMINO-3-(3-BROMO-4-HYDROXY-5-METHOXY-PHENYL)-PROPIONIC ACID
C10H12BrNO4 (288.99496519999997)
3-AMINO-3-(5-BROMO-3-METHOXY-2-HYDROXY-PHENYL)-PROPIONIC ACID
C10H12BrNO4 (288.99496519999997)
5-(4-CHLOROBENZYLSULFONYL)-1,3,4-THIADIAZOL-2-AMINE
2-(4-BROMO-3-METHYLPHENYL)ISOTHIAZOLIDINE 1,1-DIOXIDE
2-(5-CHLORO-THIOPHEN-2-YL)-QUINOLINE-4-CARBOXYLIC ACID
(5r)-3-(4-bromo-3-fluorophenyl)-5-hydroxymethyloxazolidin-2-one
2-(4-bromo-2,5-dimethoxyphenyl)-2-methoxyethanamine
3-(4-BROMO-3-FLUOROPHENYL)-5-HYDROXYMETHYLOXAZOLIDIN-2-ONE
1-[(2,2,2-TRICHLOROETHOXY)CARBONYL]-PYRROLIDINE-2-CARBOXYLIC ACID
C8H10Cl3NO4 (288.96753900000004)
1-(4-bromophenyl)-2,2,2-trifluoroethan-1-aminehydrochloride
PYRIDINE-4-CARBOXYLIC ACID PENTAFLUOROPHENYL ESTER
2-Ethylsulfonylimidazo[1,2-a]pyridine-3-sulfonamide
Tizanidine hydrochloride
D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D010276 - Parasympatholytics C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C87053 - Adrenergic Agonist D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D000322 - Adrenergic Agonists D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D018373 - Peripheral Nervous System Agents > D009465 - Neuromuscular Agents D002491 - Central Nervous System Agents > D000927 - Anticonvulsants D002491 - Central Nervous System Agents > D000700 - Analgesics Tizanidine hydrochloride is an α2-adrenergic receptor agonist and inhibits neurotransmitter release from CNS noradrenergic neurons. Target: α2-adrenergic receptor Tizanidine is a drug that is used as a muscle relaxant. It is a centrally acting α2 adrenergic agonist. It is used to treat the spasms, cramping, and tightness of muscles caused by medical problems such as multiple sclerosis, ALS, spastic diplegia, back pain, or certain other injuries to the spine or central nervous system. It is also prescribed off-label for migraine headaches, as a sleep aid, and as an anticonvulsant. It is also prescribed for some symptoms of fibromyalgia. Tizanidine has been found to be as effective as other antispasmodic drugs and has superior tolerability to that of baclofen and diazepam. Tizanidine can be very strong even at the 2 mg dose and may cause hypotension, so caution is advised when it is used in patients who have a history of orthostatic hypotension, or when switching from gel cap to tablet form and vice versa. Tizanidine can occasionally cause liver damage, generally the hepatocellular type. Clinical trials show that up to 5\% of patients treated with tizanidine had elevated liver function test values, though symptoms disappeared upon withdrawal of the drug. Care should be used when first beginning treatment with tizanidine with regular liver tests for the first 6 months of treatment.
4-Bromo-8-methyl-2-(trifluoromethyl)quinoline
C11H7BrF3N (288.97139180000005)
1-Propanone,3-chloro-1-(10H-phenothiazin-10-yl)-
C15H12ClNOS (289.03280920000003)
3-(2,6-DICHLOROPHENYL)-5-METHYLISOXAZOLE-4-CARBONYL CHLORIDE
C11H6Cl3NO2 (288.94641060000004)
AMINO-(3-BROMO-4,5-DIMETHOXY-PHENYL)-ACETIC ACID
C10H12BrNO4 (288.99496519999997)
6-(CHLOROMETHYL)-2-[5-(TRIFLUOROMETHYL)-2-PYRIDYL]PYRIMIDIN-4-OL
6-BROMO-3-(3H-IMIDAZOL-4-YLMETHYLENE)-1,3-DIHYDRO-INDOL-2-ONE
METHYL 4,6,7-TRICHLORO-QUINOLINE-2-CARBOXYLATE
C11H6Cl3NO2 (288.94641060000004)
(R)-1-(4-BROMOPHENYL)-2,2,2-TRIFLUOROETHYLAMINE HCL
1-Bromo-4,5-diethoxy-2-nitrobenzene
C10H12BrNO4 (288.99496519999997)
5-bromo-N-butyl-2-chlorobenzamide
C11H13BrClNO (288.98689780000007)
1-Propanone,2-chloro-1-(10H-phenothiazin-10-yl)-
C15H12ClNOS (289.03280920000003)
6-(Bromomethyl)-2-(trifluoromethyl)quinoline
C11H7BrF3N (288.97139180000005)
4-(6-Bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)-2-pyrimidinamine
4-(4-Bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)-2-pyrimidinamine
(2-(4-(TRIFLUOROMETHYL)PHENYL)THIAZOLE-4,5-DIYL)DIMETHANOL
methyl 4-chloro-2-(trifluoromethyl)quinoline-6-carboxylate
3-[(2-HYDROXYETHYL)THIO]-6-NITRO-2,3-DIHYDRO-1H-1LAMBDA6-BENZO[B]THIOPHENE-1,1-DIONE
2-(5-BROMO-FURAN-2-YL)-2,3-DIHYDRO-BENZOFURAN-5-CARBONITRILE
Carbamic acid, N-(5-bromo-2-nitro-3-pyridinyl)-, ethyl ester
5-Bromo-1,2-dicarboxylic acid-1H-Pyrrole 1-(1,1-dimethylethyl) ester
C10H12BrNO4 (288.99496519999997)
Propanedinitrile, 2-(4-oxo-3- phenyl-2-selenazolidinylidene)-
1-(4-broMo-2,3-difluorophenyl)-4-Methylpiperidine
C12H14BrF2N (289.02776080000007)
METHYL 4-CHLORO-6-TRIFLUOROMETHYL-QUINOLINE-2-CARBOXYLATE
2-Bromo-N-methyl-5-(trifluoromethyl)aniline hydrochloride
4-Bromo-N-methyl-2-(trifluoromethyl)aniline hydrochloride
(3-(4-CHLOROBENZO[D]THIAZOL-2-YL)PHENYL)BORONIC ACID
C13H9BClNO2S (289.01355540000003)
dicarbonyl(pentamethylcyclopentadienyl)molybdenum dimer
Benzenesulfonylchloride, 4-nitro-3-(trifluoromethyl)-
C7H3ClF3NO4S (288.94234240000003)
4-Bromo-6-methyl-2-(trifluoromethyl)quinoline
C11H7BrF3N (288.97139180000005)
2-(2,4-DICHLOROPHENOXY)ANILINE HYDROCHLORIDE
C12H10Cl3NO (288.98279400000007)
1-(5-Chloroindol-3-YL)-3-hydroxy-3-(2H-tetrazol-5-YL)-propenone
C12H8ClN5O2 (289.03664979999996)
(4-Methoxyphenyl)(morpholino)phosphinodithioic acid
5-Hydroxy-7-(4-nitrophenyl)-1,3-benzoxathiol-2-one
5-phosphonato-alpha-D-ribose cyclic-1,2-phosphate(3-)
(2S)-5-[[amino-(sulfonatoamino)phosphoryl]amino]-2-azaniumylpentanoate
C5H14N4O6PS- (289.03716540000005)
5-Chloropyridin-3-yl benzo[b]thiophene-2-carboxylate
(2Z)-2-[(4-chlorophenyl)sulfonylmethylidene]-1,3-thiazolidin-4-one
6-Chloro-3-[2-(2-furanyl)-2-oxoethyl]-1,4-benzoxazin-2-one
QUINETHAZONE
C - Cardiovascular system > C03 - Diuretics > C03B - Low-ceiling diuretics, excl. thiazides > C03BA - Sulfonamides, plain D045283 - Natriuretic Agents > D004232 - Diuretics > D049993 - Sodium Chloride Symporter Inhibitors C78275 - Agent Affecting Blood or Body Fluid > C448 - Diuretic > C49185 - Thiazide Diuretic D002317 - Cardiovascular Agents > D045283 - Natriuretic Agents D049990 - Membrane Transport Modulators