Exact Mass: 230.1378838

Exact Mass Matches: 230.1378838

Found 260 metabolites which its exact mass value is equals to given mass value 230.1378838, within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error 0.001 dalton.

(-)-dehydrocostus lactone

Azuleno(4,5-b)furan-2(3H)-one, decahydro-3,6,9-tris(methylene)-, (3aS-(3a.alpha.,6a.alpha.,9a.alpha.,9b.beta.))-

C15H18O2 (230.1306728)


Dehydrocostus lactone is an organic heterotricyclic compound and guaianolide sesquiterpene lactone that is acrylic acid which is substituted at position 2 by a 4-hydroxy-3,8-bis(methylene)decahydoazulen-5-yl group and in which the hydroxy group and the carboxy group have undergone formal condensation to afford the corresponding gamma-lactone. It has a role as a metabolite, a trypanocidal drug, an antineoplastic agent, a cyclooxygenase 2 inhibitor, an antimycobacterial drug and an apoptosis inducer. It is a sesquiterpene lactone, a guaiane sesquiterpenoid, an organic heterotricyclic compound and a gamma-lactone. Dehydrocostus lactone is a natural product found in Marshallia obovata, Cirsium carolinianum, and other organisms with data available. See also: Arctium lappa Root (part of). An organic heterotricyclic compound and guaianolide sesquiterpene lactone that is acrylic acid which is substituted at position 2 by a 4-hydroxy-3,8-bis(methylene)decahydoazulen-5-yl group and in which the hydroxy group and the carboxy group have undergone formal condensation to afford the corresponding gamma-lactone. CONFIDENCE standard compound; ML_ID 36 Dehydrocostus Lactone is a major sesquiterpene lactone isolated from the roots of Saussurea costus. IC50 value: Target: In vitro: Dehydrocostus Lactone promoted apoptosis with increased activation of caspases 8, 9, 7, 3, enhanced PARP cleavage, decreased Bcl-xL expression and increased levels of Bax, Bak, Bok, Bik, Bmf, and t-Bid. We have demonstrated that Dehydrocostus Lactone inhibits cell growth and induce apoptosis in DU145 cells [1]. Dehydrocostus Lactone inhibits NF-kappaB activation by preventing TNF-alpha-induced degradation and phosphorylation of its inhibitory protein I-kappaB alpha in human leukemia HL-60 cells and that dehydrocostus lactone renders HL-60 cells susceptible to TNF-alpha-induced apoptosis by enhancing caspase-8 and caspase-3 activities [2]. Dehydrocostus Lactone inhibited the production of NO in lipopolysaccharide (LPS)-activated RAW 264.7 cells by suppressing inducible nitric oxide synthase enzyme expression. In vivo: Dehydrocostus Lactone decreased the TNF-alpha level in LPS-activated systems in vivo [3]. Dehydrocostus Lactone is a major sesquiterpene lactone isolated from the roots of Saussurea costus. IC50 value: Target: In vitro: Dehydrocostus Lactone promoted apoptosis with increased activation of caspases 8, 9, 7, 3, enhanced PARP cleavage, decreased Bcl-xL expression and increased levels of Bax, Bak, Bok, Bik, Bmf, and t-Bid. We have demonstrated that Dehydrocostus Lactone inhibits cell growth and induce apoptosis in DU145 cells [1]. Dehydrocostus Lactone inhibits NF-kappaB activation by preventing TNF-alpha-induced degradation and phosphorylation of its inhibitory protein I-kappaB alpha in human leukemia HL-60 cells and that dehydrocostus lactone renders HL-60 cells susceptible to TNF-alpha-induced apoptosis by enhancing caspase-8 and caspase-3 activities [2]. Dehydrocostus Lactone inhibited the production of NO in lipopolysaccharide (LPS)-activated RAW 264.7 cells by suppressing inducible nitric oxide synthase enzyme expression. In vivo: Dehydrocostus Lactone decreased the TNF-alpha level in LPS-activated systems in vivo [3].

   

Lindeneol

Cycloprop[2,3]indeno[5,6-b]furan-4-ol, 4,4a,5,5a,6,6a,6b,7-octahydro-3,6b-dimethyl-5-methylene-, (4R,4aS,5aS,6aR,6bS)-

C15H18O2 (230.1306728)


Linderenol is a member of benzofurans. Linderene is a natural product found in Lindera chunii and Lindera pulcherrima var. hemsleyana with data available. Lindenenol is isolated from Radix linderae, with antioxidant and antibacterial activities[1]. Lindenenol is isolated from Radix linderae, with antioxidant and antibacterial activities[1].

   

Atractylenolide

(4aS-trans)- 4a,5,6,7,8,8a-hexahydro-3,8a-dimethyl-5-methylenenaphtho[2,3-b]furan-2(4H)-one

C15H18O2 (230.1306728)


Atractylenolide I is a natural product found in Solanum lyratum, Atractylodes japonica, and other organisms with data available. Atractylenolide I is a sesquiterpene derived from the rhizome of Atractylodes macrocephala, possesses diverse bioactivities, such as neuroprotective, anti-allergic, anti-inflammatory and anticancer properties. Atractylenolide I reduces protein levels of phosphorylated JAK2 and STAT3 in A375 cells, and acts as a TLR4-antagonizing agent. Atractylenolide I is a sesquiterpene derived from the rhizome of Atractylodes macrocephala, possesses diverse bioactivities, such as neuroprotective, anti-allergic, anti-inflammatory and anticancer properties. Atractylenolide I reduces protein levels of phosphorylated JAK2 and STAT3 in A375 cells, and acts as a TLR4-antagonizing agent.

   

Furanodienone

CYCLODECA(B)FURAN-4(7H)-ONE, 8,11-DIHYDRO-3,6,10-TRIMETHYL-, (5E,9E)-

C15H18O2 (230.1306728)


Furanodienone is a germacrane sesquiterpenoid. (5E,9E)-3,6,10-trimethyl-8,11-dihydro-7H-cyclodeca[b]furan-4-one is a natural product found in Curcuma amada, Curcuma aeruginosa, and other organisms with data available. Isofuranodienone is a constituent of Curcuma zedoaria (zedoary). Constituent of Curcuma zedoaria (zedoary) Furanodienone is one of the major bioactive constituents derived from Rhizoma Curcumae. Furanodienone induced apoptosis[1]. Furanodienone is one of the major bioactive constituents derived from Rhizoma Curcumae. Furanodienone induced apoptosis[1].

   

Curzerenone

4(5H)-Benzofuranone, 6-ethenyl-6,7-dihydro-3,6-dimethyl-5-(1-methylethenyl)-, (5R,6R)-rel-

C15H18O2 (230.1306728)


Constituent of Curcuma zedoaria (zedoary). Curzerenone is found in turmeric. 5-Epicurzerenone is from Curcuma zedoaria (zedoary Curzerenone is a monoterpenoid. 4(5H)-Benzofuranone, 6-ethenyl-6,7-dihydro-3,6-dimethyl-5-(1-methylethenyl)-, trans- is a natural product found in Prumnopitys andina, Curcuma aeruginosa, and other organisms with data available. Curzerenone is one of constituents of leaf essential oil extracted from L. pulcherrima. Shows slight inhibitory effective against E. coli[1]. Curzerenone is one of constituents of leaf essential oil extracted from L. pulcherrima. Shows slight inhibitory effective against E. coli[1].

   

Eremanthin

(3aS,6aR,9aR,9bS)-6-methyl-3,9-dimethylidene-2H,3H,3aH,4H,6aH,7H,8H,9H,9aH,9bH-azuleno[4,5-b]furan-2-one

C15H18O2 (230.1306728)


Eremanthin belongs to guaianolides and derivatives class of compounds. Those are diterpene lactones with a structure characterized by the presence of a gamma-lactone fused to a guaiane, forming 3,6,9-trimethyl-azuleno[4,5-b]furan-2-one or a derivative. Eremanthin is practically insoluble (in water) and an extremely weak basic (essentially neutral) compound (based on its pKa). Eremanthin can be found in sweet bay, which makes eremanthin a potential biomarker for the consumption of this food product.

   

Dehydromyodesmone

(S)-1-(2-(3-Furanyl)-5-methyl-1-cyclopenten-1-yl)-3-methyl-2-buten-1-one

C15H18O2 (230.1306728)


   

Camoensine

Oprea1_574945

C14H18N2O (230.1419058)


   

MLS002694008

3-(1,2,3,4-Tetrahydro-6-hydroxy-2-naphthyl)cyclopentanone

C15H18O2 (230.1306728)


   

Isodehydrocostus lactone

Isodehydrocostus lactone

C15H18O2 (230.1306728)


   

(2E,8Z)-Decadiene-4,6-diyn-1-yl 3-methylbutanoate

(2E,8Z)-Decadiene-4,6-diyn-1-yl 3-methylbutanoic acid

C15H18O2 (230.1306728)


(2E,8Z)-Decadiene-4,6-diyn-1-yl 3-methylbutanoate is found in fats and oils. (2E,8Z)-Decadiene-4,6-diyn-1-yl 3-methylbutanoate is a constituent of Carthamus tinctorius (safflower) Constituent of Carthamus tinctorius (safflower). (2E,8Z)-Decadiene-4,6-diyn-1-yl 3-methylbutanoate is found in fats and oils and herbs and spices.

   

8,12-Epoxy-4(15),7,11-eudesmatrien-1-one

3,8a-dimethyl-5-methylidene-4H,4aH,5H,6H,7H,8H,8aH,9H-naphtho[2,3-b]furan-8-one

C15H18O2 (230.1306728)


8,12-Epoxy-4(15),7,11-eudesmatrien-1-one is found in green vegetables. 8,12-Epoxy-4(15),7,11-eudesmatrien-1-one is a constituent of Smyrnium olusatrum (alexanders). Constituent of Smyrnium olusatrum (alexanders). 8,12-Epoxy-4(15),7,11-eudesmatrien-1-one is found in green vegetables.

   

Ibudilast

2-methyl-1-[2-(propan-2-yl)pyrazolo[1,5-a]pyridin-3-yl]propan-1-one

C14H18N2O (230.1419058)


Ibudilast is an anti-inflammatory and neuroprotective oral agent which shows an excellent safety profile at 60 mg/day and provides significantly prolonged time-to-first relapse and attenuated brain volume shrinkage in patients with relapsing-remitting (RR) and/or secondary progressive (SP) multiple sclerosis (MS). Ibudilast is currently in development in the U.S. (codes: AV-411 or MN-166), but is approved for use as an antiinflammatory in Japan. R - Respiratory system > R03 - Drugs for obstructive airway diseases > R03D - Other systemic drugs for obstructive airway diseases > R03DC - Leukotriene receptor antagonists D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents > D001993 - Bronchodilator Agents COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials C78274 - Agent Affecting Cardiovascular System > C29707 - Vasodilating Agent C78275 - Agent Affecting Blood or Body Fluid > C1327 - Antiplatelet Agent D006401 - Hematologic Agents > D010975 - Platelet Aggregation Inhibitors D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents D004791 - Enzyme Inhibitors > D010726 - Phosphodiesterase Inhibitors D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS

   

Cyclohexyl cinnamate

2-Propenoic acid, 3-phenyl-, cyclohexyl ester

C15H18O2 (230.1306728)


Cyclohexyl cinnamate is a flavouring ingredient. Flavouring ingredient

   

(1E)-1-{[(Diaminomethylidene)amino]imino}-2,3-dihydro-1H-indene-4-carboximidamide

(1E)-1-{[(Diaminomethylidene)amino]imino}-2,3-dihydro-1H-indene-4-carboximidamide

C11H14N6 (230.1279884)


   

Atractylenolide I

3,8a-dimethyl-5-methylidene-2H,4H,4aH,5H,6H,7H,8H,8aH-naphtho[2,3-b]furan-2-one

C15H18O2 (230.1306728)


   

Cacalol

3,4,5-trimethyl-5H,6H,7H,8H-naphtho[2,3-b]furan-9-ol

C15H18O2 (230.1306728)


   

Dehydrocostus lactone

3,6,9-trimethylidene-dodecahydroazuleno[4,5-b]furan-2-one

C15H18O2 (230.1306728)


Dehydrocostus lactone, also known as dehydro-alpha-curcumene, belongs to guaianolides and derivatives class of compounds. Those are diterpene lactones with a structure characterized by the presence of a gamma-lactone fused to a guaiane, forming 3,6,9-trimethyl-azuleno[4,5-b]furan-2-one or a derivative. Dehydrocostus lactone is practically insoluble (in water) and an extremely weak basic (essentially neutral) compound (based on its pKa). Dehydrocostus lactone can be found in burdock and sweet bay, which makes dehydrocostus lactone a potential biomarker for the consumption of these food products.

   

Propyphenazone

1,5-dimethyl-2-phenyl-4-(propan-2-yl)-2,3-dihydro-1H-pyrazol-3-one

C14H18N2O (230.1419058)


N - Nervous system > N02 - Analgesics > N02B - Other analgesics and antipyretics > N02BB - Pyrazolones C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics D000893 - Anti-Inflammatory Agents D018501 - Antirheumatic Agents

   

Curzerenone C

(5R,6R)-6-ethenyl-3,6-dimethyl-5-(prop-1-en-2-yl)-4,5,6,7-tetrahydro-1-benzofuran-4-one

C15H18O2 (230.1306728)


Curzerenone c is a member of the class of compounds known as aromatic monoterpenoids. Aromatic monoterpenoids are monoterpenoids containing at least one aromatic ring. Curzerenone c is practically insoluble (in water) and an extremely weak acidic compound (based on its pKa). Curzerenone c can be found in turmeric, which makes curzerenone c a potential biomarker for the consumption of this food product. Curzerenone is one of constituents of leaf essential oil extracted from L. pulcherrima. Shows slight inhibitory effective against E. coli[1]. Curzerenone is one of constituents of leaf essential oil extracted from L. pulcherrima. Shows slight inhibitory effective against E. coli[1].

   

2-(3-Methyl-2-butenyl)-3,6-dimethylbenzofuran-5-ol

2-(3-Methyl-2-butenyl)-3,6-dimethylbenzofuran-5-ol

C15H18O2 (230.1306728)


   
   

Kauniolide

(3aS,9aS,9bS)-6,9-dimethyl-3-methylidene-2H,3H,3aH,4H,5H,7H,9aH,9bH-azuleno[4,5-b]furan-2-one

C15H18O2 (230.1306728)


Kauniolide is a natural product found in Critonia quadrangularis and Kaunia ignorata with data available.

   

Geigeriafulvenolide

Geigeriafulvenolide

C15H18O2 (230.1306728)


   
   

CHLORANTHUS JAPONICUS SIEB

CHLORANTHUS JAPONICUS SIEB

C15H18O2 (230.1306728)


   

4-Hydroxy-2-isopropyl-4,7-dimethyl-1(4H)-naphthalenone

4-Hydroxy-2-isopropyl-4,7-dimethyl-1(4H)-naphthalenone

C15H18O2 (230.1306728)


   

Herbertenolide

(3aS-trans)-2,3,3a,9b-Tetrahydro-3a,8,9b-trimethylcyclopenta[c][1]benzopyran-4(1H)-one

C15H18O2 (230.1306728)


   
   

Dehydropinguisanin

Dehydropinguisanin

C15H18O2 (230.1306728)


   

Laurequinone

[1S-(1alpha,2beta,5alpha)]-2-(1,2-Dimethylbicyclo[3.1.0]hex-2-yl)-5-methyl-2,5-cyclohexadiene-1,4-dione

C15H18O2 (230.1306728)


   

Isocinariolide

(S)-6,7,8,9-Tetrahydro-9-methyl-1-methylene-3-(1-methylethenyl)-2-benzoxepin-5(1H)-one

C15H18O2 (230.1306728)


   

Gazaniolide

[3aS-(3aalpha,5abeta,9aalpha,9bbeta)]-3a,4,5,5a,9a,9b-Hexahydro-5a,9-dimethyl-3-methylenenaphtho[1,2-b]furan-2(3H)-one

C15H18O2 (230.1306728)


   
   

Secocrispiolide

(S)-4-[(2,6-Dimethylphenyl)methyl]tetrahydro-3-methylene-2H-pyran-2-one

C15H18O2 (230.1306728)


   
   

1(2H)-Naphthalenone, 3,4-dihydro-4-hydroxy-2-(3-methyl-2-butenyl)-, (2R,4R)- ; 1(2H)-Naphthalenone, 3,4-dihydro-4-hydroxy-2-(3-methyl-2-butenyl)-, (2R,4S)-

1(2H)-Naphthalenone, 3,4-dihydro-4-hydroxy-2-(3-methyl-2-butenyl)-, (2R,4R)- ; 1(2H)-Naphthalenone, 3,4-dihydro-4-hydroxy-2-(3-methyl-2-butenyl)-, (2R,4S)-

C15H18O2 (230.1306728)


   
   
   

Germacrene-D-lactone

Germacrene-D-lactone

C15H18O2 (230.1306728)


   

Aoifuranone

(+)-Aoifuranone

C15H18O2 (230.1306728)


   

10alpha-Furanoligularenone

10alpha-Furanoligularenone

C15H18O2 (230.1306728)


   

Dihydrostahlianthusone

Dihydrostahlianthusone

C15H18O2 (230.1306728)


   

Furanoplagiochilal

Furanoplagiochilal

C15H18O2 (230.1306728)


   

(4aR-cis)-4a,5,6,7-Tetrahydro-3,4a,5-trimethyl-naphtho[2,3-b]furan-8(4H)-one

(4aR-cis)-4a,5,6,7-Tetrahydro-3,4a,5-trimethyl-naphtho[2,3-b]furan-8(4H)-one

C15H18O2 (230.1306728)


   

Emmotin G

3-Hydroxy-a,a,5,8-tetramethyl-2-naphthalenemethanol

C15H18O2 (230.1306728)


   

Dehydrobotrydienal

Dehydrobotrydienal

C15H18O2 (230.1306728)


   
   
   

10-Oxodehydrodihydrobotrydial

(+)-10-Oxodehydrodihydrobotrydial

C15H18O2 (230.1306728)


   

Warburgiadione

Eremophila-1,7(11),9-triene-3,8-dione

C15H18O2 (230.1306728)


   

Lindestrenolide

[4aS-(4aalpha,8abeta,9abeta)]-4a,5,6,8a,9,9a-Hexahydro-3,8a-dimethyl-5-methylenenaphtho[2,3-b]furan-2(4H)-one

C15H18O2 (230.1306728)


   

Furanocaulesone A

Furanocaulesone A

C15H18O2 (230.1306728)


   

1,2,4,15-Tetrahydro-4,5-dihydrosteiractinolide

[3aR-(3aalpha,4abeta,8aalpha,9aalpha)]-3a,4,4a,5,6,8a,9,9a-Octahydro-8a-methyl-3,5-bis(methylene)-naphtho[2,3-b]furan-2(3H)-one

C15H18O2 (230.1306728)


   
   

Laurentristich-4-ol

Laurentristich-4-ol

C15H18O2 (230.1306728)


   
   

11alpha-Allylcytisine

11alpha-Allylcytisine

C14H18N2O (230.1419058)


   

Isoalantodiene

[3aR-(3aalpha,8abeta,9aalpha)]-3a,7,8,8a,9,9a-Hexahydro-5,8a-dimethyl-3-methylenenaphtho[2,3-b]furan-2(3H)-one

C15H18O2 (230.1306728)


   
   

Dehydrolasiosperman

Dehydrolasiosperman

C15H18O2 (230.1306728)


   
   

4-(p-Methoxyphenyl)cyclohex-2-en-1-one

4-(p-Methoxyphenyl)cyclohex-2-en-1-one

C15H18O2 (230.1306728)


   
   

5-Ketonakafuran 8

5-Ketonakafuran 8

C15H18O2 (230.1306728)


   

Alantodiene

(8aR-trans)-6,7,8,8a,9,9a-Hexahydro-5,8a-dimethyl-3-methylenenaphtho[2,3-b]furan-2(3H)-one

C15H18O2 (230.1306728)


   

13-Deoxyisoonoceriolide

[3aR-(3aalpha,4abeta,5abeta,6abeta,6balpha,7aalpha)]-Decahydro-6b-methyl-3,5-bis(methylene)cycloprop[2,3]indeno[5,6-b]furan-2(3H)-one

C15H18O2 (230.1306728)


   
   

Dehydroisomyodesmone

Dehydroisomyodesmone

C15H18O2 (230.1306728)


   
   

9-Oxoeuryopsin

Furanoeremophil-1(10)-en-9-one

C15H18O2 (230.1306728)


   

8,9-Dehydroverboccidentalactone

8,9-Dehydroverboccidentalactone

C15H18O2 (230.1306728)


   
   
   
   
   

dehydrocostus lactone

NCGC00385838-01_C15H18O2_Azuleno[4,5-b]furan-2(3H)-one, decahydro-3,6,9-tris(methylene)-, (3aS,6aR,9aR,9bS)-

C15H18O2 (230.1306728)


Dehydrocostus Lactone is a major sesquiterpene lactone isolated from the roots of Saussurea costus. IC50 value: Target: In vitro: Dehydrocostus Lactone promoted apoptosis with increased activation of caspases 8, 9, 7, 3, enhanced PARP cleavage, decreased Bcl-xL expression and increased levels of Bax, Bak, Bok, Bik, Bmf, and t-Bid. We have demonstrated that Dehydrocostus Lactone inhibits cell growth and induce apoptosis in DU145 cells [1]. Dehydrocostus Lactone inhibits NF-kappaB activation by preventing TNF-alpha-induced degradation and phosphorylation of its inhibitory protein I-kappaB alpha in human leukemia HL-60 cells and that dehydrocostus lactone renders HL-60 cells susceptible to TNF-alpha-induced apoptosis by enhancing caspase-8 and caspase-3 activities [2]. Dehydrocostus Lactone inhibited the production of NO in lipopolysaccharide (LPS)-activated RAW 264.7 cells by suppressing inducible nitric oxide synthase enzyme expression. In vivo: Dehydrocostus Lactone decreased the TNF-alpha level in LPS-activated systems in vivo [3]. Dehydrocostus Lactone is a major sesquiterpene lactone isolated from the roots of Saussurea costus. IC50 value: Target: In vitro: Dehydrocostus Lactone promoted apoptosis with increased activation of caspases 8, 9, 7, 3, enhanced PARP cleavage, decreased Bcl-xL expression and increased levels of Bax, Bak, Bok, Bik, Bmf, and t-Bid. We have demonstrated that Dehydrocostus Lactone inhibits cell growth and induce apoptosis in DU145 cells [1]. Dehydrocostus Lactone inhibits NF-kappaB activation by preventing TNF-alpha-induced degradation and phosphorylation of its inhibitory protein I-kappaB alpha in human leukemia HL-60 cells and that dehydrocostus lactone renders HL-60 cells susceptible to TNF-alpha-induced apoptosis by enhancing caspase-8 and caspase-3 activities [2]. Dehydrocostus Lactone inhibited the production of NO in lipopolysaccharide (LPS)-activated RAW 264.7 cells by suppressing inducible nitric oxide synthase enzyme expression. In vivo: Dehydrocostus Lactone decreased the TNF-alpha level in LPS-activated systems in vivo [3].

   

dehydrocostuslactone

3,6,9-trimethylidene-3a,4,5,6a,7,8,9a,9b-octahydroazuleno[4,5-b]furan-2-one

C15H18O2 (230.1306728)


   

3,9-Cadalenediol

2,7-dihydroxycadalene

C15H18O2 (230.1306728)


   

Linderene

(4R,4aS,5aS,6aR,6bS)-4,4a,5,5a,6,6a,6b,7-Octahydro-3,6b-dimethyl-5-methylenecycloprop[2,3]indeno[5,6-b]furan-4-ol

C15H18O2 (230.1306728)


Lindenenol is isolated from Radix linderae, with antioxidant and antibacterial activities[1]. Lindenenol is isolated from Radix linderae, with antioxidant and antibacterial activities[1].

   

Furanodienon

CYCLODECA(B)FURAN-4(7H)-ONE, 8,11-DIHYDRO-3,6,10-TRIMETHYL-, (5E,9E)-

C15H18O2 (230.1306728)


Furanodienone is a germacrane sesquiterpenoid. (5E,9E)-3,6,10-trimethyl-8,11-dihydro-7H-cyclodeca[b]furan-4-one is a natural product found in Curcuma amada, Curcuma aeruginosa, and other organisms with data available. Furanodienone is one of the major bioactive constituents derived from Rhizoma Curcumae. Furanodienone induced apoptosis[1]. Furanodienone is one of the major bioactive constituents derived from Rhizoma Curcumae. Furanodienone induced apoptosis[1].

   

Furanocaulesone B

Furanocaulesone B

C15H18O2 (230.1306728)


   

Furanocaulesone C

Furanocaulesone C

C15H18O2 (230.1306728)


   

1(10)Z,4Z-furanodiene-6-one

1(10)Z,4Z-furanodiene-6-one

C15H18O2 (230.1306728)


   

Propyphenazone

4-Isopropylantipyrine

C14H18N2O (230.1419058)


N - Nervous system > N02 - Analgesics > N02B - Other analgesics and antipyretics > N02BB - Pyrazolones C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics D000893 - Anti-Inflammatory Agents D018501 - Antirheumatic Agents CONFIDENCE standard compound; INTERNAL_ID 2653 CONFIDENCE standard compound; INTERNAL_ID 2272 CONFIDENCE standard compound; INTERNAL_ID 8550

   

Procerin

2-hydroxy-5-(3-methylbut-2-en-1-yl)-4-(prop-1-en-2-yl)cyclohepta-2,4,6-trien-1-one

C15H18O2 (230.1306728)


   

8,9-Dehydrothymol 3-O-tiglate

8,9-Dehydrothymol 3-O-tiglate

C15H18O2 (230.1306728)


   

4-hydroxy-4,7-dimethyl-2-(propan-2-yl)naphthalen-1(4h)-one

4-hydroxy-4,7-dimethyl-2-(propan-2-yl)naphthalen-1(4h)-one

C15H18O2 (230.1306728)


   

2,3-8,9-Bisanhydrolactarorufin

2,3-8,9-Bisanhydrolactarorufin

C15H18O2 (230.1306728)


   

8,10,14-Pentadecatriene-4,6-diyne-3,12-diol|pentadeca-8t,10t,14-triene-4,6-diyne-3,12-diol

8,10,14-Pentadecatriene-4,6-diyne-3,12-diol|pentadeca-8t,10t,14-triene-4,6-diyne-3,12-diol

C15H18O2 (230.1306728)


   
   

pentadeca-6,8,10-triynoic acid

pentadeca-6,8,10-triynoic acid

C15H18O2 (230.1306728)


   
   

(6S)-2-methyl-6-(4-formylphenyl)-2-hepten-4-one

(6S)-2-methyl-6-(4-formylphenyl)-2-hepten-4-one

C15H18O2 (230.1306728)


   

pentadeca-(9E)-ene-11,13-diyne-2,8-dione

pentadeca-(9E)-ene-11,13-diyne-2,8-dione

C15H18O2 (230.1306728)


   
   

1-Oxo-cinalbicol|1-oxocinalbicol

1-Oxo-cinalbicol|1-oxocinalbicol

C15H18O2 (230.1306728)


   

10-Epigazaniolide

10-Epigazaniolide

C15H18O2 (230.1306728)


   

1,2-Dimethyl-6-methoxy-1,2,3,4-tetrahydro-beta-carboline

1,2-Dimethyl-6-methoxy-1,2,3,4-tetrahydro-beta-carboline

C14H18N2O (230.1419058)


   
   
   

1,9-Epoxy-1,3,5,10-bisabolatetraen-12-al|1,9-Epoxy-1,3,5,10-bisabolatetraen-12-ol

1,9-Epoxy-1,3,5,10-bisabolatetraen-12-al|1,9-Epoxy-1,3,5,10-bisabolatetraen-12-ol

C15H18O2 (230.1306728)


   

1-propyl-2,3,4,9-tetrahydro-1H-beta-carbolin-6-ol|1-Propyl-6-hydroxy-1,2,3,4-tetrahydro-2-carboline|1-Propyl-6-hydroxyl-1,2,3,4-tetrahydro-beta-carboline|schobericine|schobicine

1-propyl-2,3,4,9-tetrahydro-1H-beta-carbolin-6-ol|1-Propyl-6-hydroxy-1,2,3,4-tetrahydro-2-carboline|1-Propyl-6-hydroxyl-1,2,3,4-tetrahydro-beta-carboline|schobericine|schobicine

C14H18N2O (230.1419058)


   

3,8-dimethyl-5-isopropyl-2,3-dihydro-1H-azulene-1,6-dione|pernambucone

3,8-dimethyl-5-isopropyl-2,3-dihydro-1H-azulene-1,6-dione|pernambucone

C15H18O2 (230.1306728)


   

1-hydroxy-pentadeca-9c,14-diene-4,6-diyn-3-one

1-hydroxy-pentadeca-9c,14-diene-4,6-diyn-3-one

C15H18O2 (230.1306728)


   

5-(p-methoxyphenethyl)cyclohex-2-enon

5-(p-methoxyphenethyl)cyclohex-2-enon

C15H18O2 (230.1306728)


   

Tetrahydro-3-methylene-4-(2,6-dimethylbenzyl)-2H-pyran-2-one

Tetrahydro-3-methylene-4-(2,6-dimethylbenzyl)-2H-pyran-2-one

C15H18O2 (230.1306728)


   

3,12-dihydroxycadalene

3,12-dihydroxycadalene

C15H18O2 (230.1306728)


   
   

Chrysorrhelactone

Chrysorrhelactone

C15H18O2 (230.1306728)


   

4-allyl-1,2,5,6,11,11a-hexahydro-1,5-methano-pyrido[1,2-a][1,5]diazocin-10-one|Dehydro-albin|Dehydroalbin

4-allyl-1,2,5,6,11,11a-hexahydro-1,5-methano-pyrido[1,2-a][1,5]diazocin-10-one|Dehydro-albin|Dehydroalbin

C14H18N2O (230.1419058)


   
   

4-Furanoeudesmen-6-one

4-Furanoeudesmen-6-one

C15H18O2 (230.1306728)


   

(1E)-8,12-epoxygermacra-1,7,10,11-tetraen-6-one

(1E)-8,12-epoxygermacra-1,7,10,11-tetraen-6-one

C15H18O2 (230.1306728)


   

(+)-aromadendra-1(10),4-dien-15-al-3-one|3-Oxo-1(10),4-aromadensradien-14-al

(+)-aromadendra-1(10),4-dien-15-al-3-one|3-Oxo-1(10),4-aromadensradien-14-al

C15H18O2 (230.1306728)


   

9-Furanomexicen-8-one

9-Furanomexicen-8-one

C15H18O2 (230.1306728)


   
   
   

1-(1,1-dimethyl-2-propenyl)-4-phenylbutan-2,4-dione|Mysorenone B

1-(1,1-dimethyl-2-propenyl)-4-phenylbutan-2,4-dione|Mysorenone B

C15H18O2 (230.1306728)


   

Furanoeremophil-1-(10)-en-9-one

Furanoeremophil-1-(10)-en-9-one

C15H18O2 (230.1306728)


   

(E)-1-(3-methyl-2-butenoyloxy)-2-decen-4,6-diyne|1-Senecionyloxy-deca-2t-en-4,6-diin

(E)-1-(3-methyl-2-butenoyloxy)-2-decen-4,6-diyne|1-Senecionyloxy-deca-2t-en-4,6-diin

C15H18O2 (230.1306728)


   
   
   
   

(7R)-14(10 ? 1)-abeoeudesma-1,3,5(10),11(13)-tetraen-12-oic acid*dichloromethane

(7R)-14(10 ? 1)-abeoeudesma-1,3,5(10),11(13)-tetraen-12-oic acid*dichloromethane

C15H18O2 (230.1306728)


   
   
   

2-oxoverboccidentafurane

2-oxoverboccidentafurane

C15H18O2 (230.1306728)


   

dec-8(E)-ene-4,6-diyne-1-ol angelate

dec-8(E)-ene-4,6-diyne-1-ol angelate

C15H18O2 (230.1306728)


   
   
   
   

5,8a-dimethyl-3-methylene-3a,7,8,8a,9,9a-hexahydro-3h-naphtho[2,3-b]furan-2-one

5,8a-dimethyl-3-methylene-3a,7,8,8a,9,9a-hexahydro-3h-naphtho[2,3-b]furan-2-one

C15H18O2 (230.1306728)


   

7,8-dehydro-alpha-isocedren-14,15-dial|7,8-dehydro-alpha-isocedrene-8,9-dial

7,8-dehydro-alpha-isocedren-14,15-dial|7,8-dehydro-alpha-isocedrene-8,9-dial

C15H18O2 (230.1306728)


   

(2R*,5S*,1E,3E)-form-Tetrahydro-5-(1,3-undecadiene-5,7-diynyl)-2-furanol,

(2R*,5S*,1E,3E)-form-Tetrahydro-5-(1,3-undecadiene-5,7-diynyl)-2-furanol,

C15H18O2 (230.1306728)


   
   

1,5,8-Trimethyl-6,7,8,9-tetrahydronaphtho[2,1-b]furan-8-ol

1,5,8-Trimethyl-6,7,8,9-tetrahydronaphtho[2,1-b]furan-8-ol

C15H18O2 (230.1306728)


   

2-Cyclohexen-1-one, 4-[2-(4-methoxyphenyl)ethyl]-

2-Cyclohexen-1-one, 4-[2-(4-methoxyphenyl)ethyl]-

C15H18O2 (230.1306728)


   
   

alpha-curcumene-12,15-dial

alpha-curcumene-12,15-dial

C15H18O2 (230.1306728)


   

2,7-dihydroxycadalene

2,7-dihydroxycadalene

C15H18O2 (230.1306728)


   

2-Hydroxy-7-methoxycadalene

2-Hydroxy-7-methoxycadalene

C15H18O2 (230.1306728)


   
   

dehydropinguisone

dehydropinguisone

C15H18O2 (230.1306728)


   

3,5-Dimethyl-6-(4-oxopentyl)benzofuran

3,5-Dimethyl-6-(4-oxopentyl)benzofuran

C15H18O2 (230.1306728)


   

Dehydropinguisanin|Dehydropingusanin

Dehydropinguisanin|Dehydropingusanin

C15H18O2 (230.1306728)


   

Shizukanolide

(1S,7S,9S,10R,12S)-4,9-dimethyl-13-methylidene-6-oxatetracyclo[7.4.0.03,7.010,12]tridec-3-en-5-one

C15H18O2 (230.1306728)


Shizukanolide is a natural product found in Chloranthus henryi, Chloranthus serratus, and Sarcandra glabra with data available.

   

Catalponol

1(2H)-Naphthalenone, 3,4-dihydro-4-hydroxy-2-(3-methyl-2-butenyl)-, (2R,4R)- ; 1(2H)-Naphthalenone, 3,4-dihydro-4-hydroxy-2-(3-methyl-2-butenyl)-, (2R,4S)-

C15H18O2 (230.1306728)


Catalponol is a natural product found in Catalpa ovata and Oroxylum indicum with data available.

   

Propyphenazon

Propyphenazone

C14H18N2O (230.1419058)


N - Nervous system > N02 - Analgesics > N02B - Other analgesics and antipyretics > N02BB - Pyrazolones C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics CONFIDENCE standard compound; INTERNAL_ID 4071 D000893 - Anti-Inflammatory Agents D018501 - Antirheumatic Agents

   
   
   

Nabumetone alcohol

Nabumetone alcohol

C15H18O2 (230.1306728)


   

15-Octadecene-9,11,13-triynoic acid

15-Octadecene-9,11,13-triynoic acid

C15H18O2 (230.1306728)


   

Ketas

2-methyl-1-[2-(propan-2-yl)pyrazolo[1,5-a]pyridin-3-yl]propan-1-one

C14H18N2O (230.1419058)


R - Respiratory system > R03 - Drugs for obstructive airway diseases > R03D - Other systemic drugs for obstructive airway diseases > R03DC - Leukotriene receptor antagonists D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents > D001993 - Bronchodilator Agents COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials C78274 - Agent Affecting Cardiovascular System > C29707 - Vasodilating Agent C78275 - Agent Affecting Blood or Body Fluid > C1327 - Antiplatelet Agent D006401 - Hematologic Agents > D010975 - Platelet Aggregation Inhibitors D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents D004791 - Enzyme Inhibitors > D010726 - Phosphodiesterase Inhibitors D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS

   

8,12-Epoxy-4(15),7,11-eudesmatrien-1-one

3,8a-dimethyl-5-methylidene-4H,4aH,5H,6H,7H,8H,8aH,9H-naphtho[2,3-b]furan-8-one

C15H18O2 (230.1306728)


   

(2E,8Z)-Decadiene-4,6-diyn-1-yl 3-methylbutanoate

(2E,8Z)-deca-2,8-dien-4,6-diyn-1-yl 3-methylbutanoate

C15H18O2 (230.1306728)


   

Cyclohexyl cinnamate

2-Propenoic acid, 3-phenyl-, cyclohexyl ester

C15H18O2 (230.1306728)


   

FA 15:6

Pentadeca-9,11,13-triynoic acid

C15H18O2 (230.1306728)


   

WE 15:6

(2E,8Z)-deca-2,8-dien-4,6-diyn-1-yl 3-methylbutanoate

C15H18O2 (230.1306728)


   
   

(4-Vinylphenyl)boronic acid, pinacol ester

(4-Vinylphenyl)boronic acid, pinacol ester

C14H19BO2 (230.14780240000002)


   

5-(diethylaminomethyl)quinolin-8-ol

5-(diethylaminomethyl)quinolin-8-ol

C14H18N2O (230.1419058)


   

1-(1H-Indol-3-ylmethyl)-4-piperidinol

1-(1H-Indol-3-ylmethyl)-4-piperidinol

C14H18N2O (230.1419058)


   

1-(1H-Indol-3-ylmethyl)-3-piperidinol

1-(1H-Indol-3-ylmethyl)-3-piperidinol

C14H18N2O (230.1419058)


   

4-(1H-INDOL-6-YL)-1-METHYL-PIPERIDIN-4-OL

4-(1H-INDOL-6-YL)-1-METHYL-PIPERIDIN-4-OL

C14H18N2O (230.1419058)


   
   

N-[4-(DIMETHYLAMINO)BENZYL]-N-(2-FURYLMETHYL)AMINE

N-[4-(DIMETHYLAMINO)BENZYL]-N-(2-FURYLMETHYL)AMINE

C14H18N2O (230.1419058)


   

2-BENZYLOXYMETHYL-4-ISOPROPYL-1H-IMIDAZOLE

2-BENZYLOXYMETHYL-4-ISOPROPYL-1H-IMIDAZOLE

C14H18N2O (230.1419058)


   

Trans-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)styrene

Trans-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)styrene

C14H19BO2 (230.14780240000002)


   

7-(PIPERIDIN-4-YL)-3,4-DIHYDROQUINOLIN-2(1H)-ONE

7-(PIPERIDIN-4-YL)-3,4-DIHYDROQUINOLIN-2(1H)-ONE

C14H18N2O (230.1419058)


   

2-(3-cyclohexenyl)ethyltrimethoxysilane

2-(3-cyclohexenyl)ethyltrimethoxysilane

C11H22O3Si (230.13381420000002)


   

Propanamide,3,3,3-nitrilotris-

Propanamide,3,3,3-nitrilotris-

C9H18N4O3 (230.1378838)


   

4-tert-Butyl-1,2,6,7-tetrahydro-8H-indeno[5,4-b]furan-8-one

4-tert-Butyl-1,2,6,7-tetrahydro-8H-indeno[5,4-b]furan-8-one

C15H18O2 (230.1306728)


   

1-Piperidineacetonitrile,a-(4-methoxyphenyl)-

1-Piperidineacetonitrile,a-(4-methoxyphenyl)-

C14H18N2O (230.1419058)


   
   

4-phenyl-2,8-diazaspiro[4.5]decan-3-one

4-phenyl-2,8-diazaspiro[4.5]decan-3-one

C14H18N2O (230.1419058)


   

5-MESITYL-1,3-CYCLOHEXANEDIONE

5-MESITYL-1,3-CYCLOHEXANEDIONE

C15H18O2 (230.1306728)


   

ethane-1,2-diol,propane-1,2-diol,propane-1,2,3-triol

ethane-1,2-diol,propane-1,2-diol,propane-1,2,3-triol

C8H22O7 (230.1365462)


   

4-Hydroxy-1-phenethyl-piperidine-4-carbonitrile

4-Hydroxy-1-phenethyl-piperidine-4-carbonitrile

C14H18N2O (230.1419058)


   

4-PHENYLBICYCLO[2.2.2]OCTANE-1-CARBOXYLIC ACID

4-PHENYLBICYCLO[2.2.2]OCTANE-1-CARBOXYLIC ACID

C15H18O2 (230.1306728)


   

2-(4-tert-butylphenyl)-5-methyl-4H-pyrazol-3-one

2-(4-tert-butylphenyl)-5-methyl-4H-pyrazol-3-one

C14H18N2O (230.1419058)


   

5-Methoxy-3-piperidin-4-yl-1H-indole

5-Methoxy-3-piperidin-4-yl-1H-indole

C14H18N2O (230.1419058)


   

5-(4-METHYL-PIPERAZIN-1-YL)-INDAN-1-ONE

5-(4-METHYL-PIPERAZIN-1-YL)-INDAN-1-ONE

C14H18N2O (230.1419058)


   

1-Benzyl-1,7-diazaspiro[4.4]nonan-6-one

1-Benzyl-1,7-diazaspiro[4.4]nonan-6-one

C14H18N2O (230.1419058)


   

3-(PYRROLIDIN-1-YLCARBONYL)-1,2,3,4-TETRAHYDROISOQUINOLINE

3-(PYRROLIDIN-1-YLCARBONYL)-1,2,3,4-TETRAHYDROISOQUINOLINE

C14H18N2O (230.1419058)


   

1-Benzyl-4-(Hydroxymethyl)piperidine-4-carbonitrile

1-Benzyl-4-(Hydroxymethyl)piperidine-4-carbonitrile

C14H18N2O (230.1419058)


   

Sardomozide

(1E)-1-{[(Diaminomethylidene)amino]imino}-2,3-dihydro-1H-indene-4-carboximidamide

C11H14N6 (230.1279884)


D000970 - Antineoplastic Agents D004791 - Enzyme Inhibitors

   

(1H-Indol-3-ylmethyl)-(tetrahydro-furan-2-ylmethyl)-amine

(1H-Indol-3-ylmethyl)-(tetrahydro-furan-2-ylmethyl)-amine

C14H18N2O (230.1419058)


   

7-BENZYL-2,7-DIAZASPIRO[4.4]NONAN-3-ONE

7-BENZYL-2,7-DIAZASPIRO[4.4]NONAN-3-ONE

C14H18N2O (230.1419058)


   

2,8-Diazaspiro[4.5]decan-1-one,2-phenyl-

2,8-Diazaspiro[4.5]decan-1-one,2-phenyl-

C14H18N2O (230.1419058)


   

6-piperidin-1-yl-3,4-dihydro-2H-isoquinolin-1-one

6-piperidin-1-yl-3,4-dihydro-2H-isoquinolin-1-one

C14H18N2O (230.1419058)


   

4-(1H-INDOL-5-YL)-1-METHYL-PIPERIDIN-4-OL

4-(1H-INDOL-5-YL)-1-METHYL-PIPERIDIN-4-OL

C14H18N2O (230.1419058)


   

4,4,5,5-tetramethyl-2-(1-phenylethenyl)-1,3,2-dioxaborolane

4,4,5,5-tetramethyl-2-(1-phenylethenyl)-1,3,2-dioxaborolane

C14H19BO2 (230.14780240000002)


   

1-(1-Phenyl-1H-tetrazol-5-yl)piperazine

1-(1-Phenyl-1H-tetrazol-5-yl)piperazine

C11H14N6 (230.1279884)


   

3-[Ethoxy(dimethyl)silyl]propyl methacrylate

3-[Ethoxy(dimethyl)silyl]propyl methacrylate

C11H22O3Si (230.13381420000002)


   

3-benzyl-3,6-diazabicyclo[3.2.2]nonan-7-one

3-benzyl-3,6-diazabicyclo[3.2.2]nonan-7-one

C14H18N2O (230.1419058)


   

butan-2-one O,O-(dimethylsilanediyl)dioxime

butan-2-one O,O-(dimethylsilanediyl)dioxime

C10H22N2O2Si (230.14504720000002)


   

BRL-54443

3-(1-methylpiperidin-4-yl)-1H-indol-5-ol

C14H18N2O (230.1419058)


BRL 54443 is a potent 5-HT1E/1F receptor agonist (Ki values are 1.1 nM and 0.7 nM respectively); displays > 30-fold selectivity over other 5-HT and dopamine receptors[1].

   

Cinnamic Acid cis-3-Hexen-1-yl Ester

2-Propenoic acid,3-phenyl-, (3Z)-3-hexen-1-yl ester

C15H18O2 (230.1306728)


   

9-Benzyl-3,9-diaza-bicyclo[4.2.1]nonan-4-one

9-Benzyl-3,9-diaza-bicyclo[4.2.1]nonan-4-one

C14H18N2O (230.1419058)


   

4-Piperidinecarbonitrile,4-(3-methoxyphenyl)-1-methyl-

4-Piperidinecarbonitrile,4-(3-methoxyphenyl)-1-methyl-

C14H18N2O (230.1419058)


   

GLYCEROL ETHOXYLATE-CO-PROPOXYLATE TRIOL

GLYCEROL ETHOXYLATE-CO-PROPOXYLATE TRIOL

C8H22O7 (230.1365462)


   

N,N-Diallyl-3-aminoacetanilide

N,N-Diallyl-3-aminoacetanilide

C14H18N2O (230.1419058)


   

acrylic acid; buta-1,3-diene; styrene

acrylic acid; buta-1,3-diene; styrene

C15H18O2 (230.1306728)


   

3-(1,2,3,4-Tetrahydro-6-hydroxy-2-naphthalenyl)cyclopentanone

3-(1,2,3,4-Tetrahydro-6-hydroxy-2-naphthalenyl)cyclopentanone

C15H18O2 (230.1306728)


   

4-(6-Methoxynaphthalen-2-yl)butan-2-ol, (+)-

4-(6-Methoxynaphthalen-2-yl)butan-2-ol, (+)-

C15H18O2 (230.1306728)


   
   

7-Methoxy-2,5-dimethyl-1,2,3,4-tetrahydropyrimido[3,4-a]-indole

7-Methoxy-2,5-dimethyl-1,2,3,4-tetrahydropyrimido[3,4-a]-indole

C14H18N2O (230.1419058)


   

Ibudilast

Ibudilast

C14H18N2O (230.1419058)


R - Respiratory system > R03 - Drugs for obstructive airway diseases > R03D - Other systemic drugs for obstructive airway diseases > R03DC - Leukotriene receptor antagonists D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents > D001993 - Bronchodilator Agents COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials C78274 - Agent Affecting Cardiovascular System > C29707 - Vasodilating Agent C78275 - Agent Affecting Blood or Body Fluid > C1327 - Antiplatelet Agent D006401 - Hematologic Agents > D010975 - Platelet Aggregation Inhibitors D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents D004791 - Enzyme Inhibitors > D010726 - Phosphodiesterase Inhibitors D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS

   

Atractylenolide I

(4aS,8aS)-3,8a-dimethyl-5-methylidene-4a,6,7,8-tetrahydro-4H-benzo[f][1]benzoxol-2-one

C15H18O2 (230.1306728)


Atractylenolide I is a sesquiterpene derived from the rhizome of Atractylodes macrocephala, possesses diverse bioactivities, such as neuroprotective, anti-allergic, anti-inflammatory and anticancer properties. Atractylenolide I reduces protein levels of phosphorylated JAK2 and STAT3 in A375 cells, and acts as a TLR4-antagonizing agent. Atractylenolide I is a sesquiterpene derived from the rhizome of Atractylodes macrocephala, possesses diverse bioactivities, such as neuroprotective, anti-allergic, anti-inflammatory and anticancer properties. Atractylenolide I reduces protein levels of phosphorylated JAK2 and STAT3 in A375 cells, and acts as a TLR4-antagonizing agent.

   

Curzerenone

4(5H)-Benzofuranone, 6-ethenyl-6,7-dihydro-3,6-dimethyl-5-(1-methylethenyl)-, (5R,6R)-rel-

C15H18O2 (230.1306728)


Curzerenone is a monoterpenoid. 4(5H)-Benzofuranone, 6-ethenyl-6,7-dihydro-3,6-dimethyl-5-(1-methylethenyl)-, trans- is a natural product found in Prumnopitys andina, Curcuma aeruginosa, and other organisms with data available. Curzerenone is one of constituents of leaf essential oil extracted from L. pulcherrima. Shows slight inhibitory effective against E. coli[1]. Curzerenone is one of constituents of leaf essential oil extracted from L. pulcherrima. Shows slight inhibitory effective against E. coli[1].

   

furanodienone

(5Z,9E)-3,6,10-trimethyl-8,11-dihydro-7H-cyclodeca[b]furan-4-one

C15H18O2 (230.1306728)


   

Ermanthin

Azuleno[4,5-b]furan-2(3H)-one, 3a,4,6a,7,8,9,9a,9b-octahydro-6-methyl-3,9-bis(methylene)-, [3aS-(3a.alpha.,6a.alpha.,9a.alpha.,9b.beta.)]-

C15H18O2 (230.1306728)


   

(2E,4E,6E,8E,10E)-2,7,11-Trimethyl-2,4,6,8,10-dodecapentenedial

(2E,4E,6E,8E,10E)-2,7,11-Trimethyl-2,4,6,8,10-dodecapentenedial

C15H18O2 (230.1306728)


   

[(2S)-2-[(E)-but-2-enoyl]oxy-3-carboxypropyl]-trimethylazanium

[(2S)-2-[(E)-but-2-enoyl]oxy-3-carboxypropyl]-trimethylazanium

C11H20NO4+ (230.139226)


   

[(E)-2-(carboxymethyl)-2-hydroxy-3-oxohex-4-enyl]-trimethylazanium

[(E)-2-(carboxymethyl)-2-hydroxy-3-oxohex-4-enyl]-trimethylazanium

C11H20NO4+ (230.139226)


   

(2-But-3-enoyloxy-3-carboxypropyl)-trimethylazanium

(2-But-3-enoyloxy-3-carboxypropyl)-trimethylazanium

C11H20NO4+ (230.139226)


   

(4aS,8aS)-3,5,8a-trimethyl-4a,7,8,8a-tetrahydronaphtho[2,3-b]furan-9(4H)-one

(4aS,8aS)-3,5,8a-trimethyl-4a,7,8,8a-tetrahydronaphtho[2,3-b]furan-9(4H)-one

C15H18O2 (230.1306728)


   

2,6,10-Trimethyldodeca-2,4,6,8,10-pentaenedial

2,6,10-Trimethyldodeca-2,4,6,8,10-pentaenedial

C15H18O2 (230.1306728)


   

(2E)-2-(3,3-Dimethyl-2,4-dihydroisoquinolin-1-ylidene)-N-methylacetamide

(2E)-2-(3,3-Dimethyl-2,4-dihydroisoquinolin-1-ylidene)-N-methylacetamide

C14H18N2O (230.1419058)


   

[(2R)-2-[(E)-but-2-enoyl]oxy-3-carboxypropyl]-trimethylazanium

[(2R)-2-[(E)-but-2-enoyl]oxy-3-carboxypropyl]-trimethylazanium

C11H20NO4+ (230.139226)


   

Octanoic acid, 7-oxo-, trimethylsilyl ester

Octanoic acid, 7-oxo-, trimethylsilyl ester

C11H22O3Si (230.13381420000002)


   

(E)-Pentamethyldisilanyltrimethylsilylethylene

(E)-Pentamethyldisilanyltrimethylsilylethylene

C10H26Si3 (230.13422359999998)


   

2-(1-Methoxy-3-phenylallyl)cyclopentanone

2-(1-Methoxy-3-phenylallyl)cyclopentanone

C15H18O2 (230.1306728)


   

3-(1,2,3,4-Tetrahydro-6-hydroxy-2-naphthyl)cyclopentanone

3-(1,2,3,4-Tetrahydro-6-hydroxy-2-naphthyl)cyclopentanone

C15H18O2 (230.1306728)


   

CJ-01

CJ-01

C15H18O2 (230.1306728)


A sesquiterpenoid that is 4,4a,7,8,8a,9-hexahydronaphtho[2,3-b]furan substituted by methyl groups at positions 3, 5 and 8a and an oxo group at position 9 (the 4aS,8aS stereoisomer). It is isolated from the methanol extract of the whole plant of Chloranthus japonicus and acts as a chitin synthase inhibitor. CJ-01 also shows antifungal activity against various human and phytophathogenic fungi.

   
   
   

(4ar,5r,8ar)-3,4a,5-trimethyl-4h,5h,8ah,9h-naphtho[2,3-b]furan-6-one

(4ar,5r,8ar)-3,4a,5-trimethyl-4h,5h,8ah,9h-naphtho[2,3-b]furan-6-one

C15H18O2 (230.1306728)


   

5a,9-dimethyl-3-methylidene-3ah,4h,5h,8h,9bh-naphtho[1,2-b]furan-2-one

5a,9-dimethyl-3-methylidene-3ah,4h,5h,8h,9bh-naphtho[1,2-b]furan-2-one

C15H18O2 (230.1306728)


   

10-methyl-3,6-dimethylidene-3ah,7h,8h,11h,11ah-cyclodeca[b]furan-2-one

10-methyl-3,6-dimethylidene-3ah,7h,8h,11h,11ah-cyclodeca[b]furan-2-one

C15H18O2 (230.1306728)


   

(3r,3as,9br)-3,6,9-trimethyl-3h,3ah,4h,5h,9bh-azuleno[4,5-b]furan-2-one

(3r,3as,9br)-3,6,9-trimethyl-3h,3ah,4h,5h,9bh-azuleno[4,5-b]furan-2-one

C15H18O2 (230.1306728)


   

5,8a-dimethyl-3-methylidene-3ah,7h,8h,9h,9ah-naphtho[2,3-b]furan-2-one

5,8a-dimethyl-3-methylidene-3ah,7h,8h,9h,9ah-naphtho[2,3-b]furan-2-one

C15H18O2 (230.1306728)


   

5-methyl-2-(prop-1-en-2-yl)phenyl (2e)-2-methylbut-2-enoate

5-methyl-2-(prop-1-en-2-yl)phenyl (2e)-2-methylbut-2-enoate

C15H18O2 (230.1306728)


   

4-[(2r,5e)-6-methyl-7-oxohept-5-en-2-yl]benzaldehyde

4-[(2r,5e)-6-methyl-7-oxohept-5-en-2-yl]benzaldehyde

C15H18O2 (230.1306728)


   

5a,9-dimethyl-3-methylidene-3ah,4h,5h,9ah,9bh-naphtho[1,2-b]furan-2-one

5a,9-dimethyl-3-methylidene-3ah,4h,5h,9ah,9bh-naphtho[1,2-b]furan-2-one

C15H18O2 (230.1306728)


   

1,5,8-trimethyl-6h,7h,9h-naphtho[2,1-b]furan-8-ol

1,5,8-trimethyl-6h,7h,9h-naphtho[2,1-b]furan-8-ol

C15H18O2 (230.1306728)


   

3-(2-hydroxypropan-2-yl)-5,8-dimethylnaphthalen-2-ol

3-(2-hydroxypropan-2-yl)-5,8-dimethylnaphthalen-2-ol

C15H18O2 (230.1306728)


   

(4ar,5s)-3,4a,5-trimethyl-4h,5h,6h,7h-naphtho[2,3-b]furan-9-one

(4ar,5s)-3,4a,5-trimethyl-4h,5h,6h,7h-naphtho[2,3-b]furan-9-one

C15H18O2 (230.1306728)


   

(6ar,9ar,9bs)-3,6,9-trimethylidene-octahydroazuleno[4,5-b]furan-2-one

(6ar,9ar,9bs)-3,6,9-trimethylidene-octahydroazuleno[4,5-b]furan-2-one

C15H18O2 (230.1306728)


   

(4r)-4-[2-(4-methoxyphenyl)ethyl]cyclohex-2-en-1-one

(4r)-4-[2-(4-methoxyphenyl)ethyl]cyclohex-2-en-1-one

C15H18O2 (230.1306728)


   

(4as,5r,8ar)-3,5,8a-trimethyl-4h,4ah,5h,9h-naphtho[2,3-b]furan-8-one

(4as,5r,8ar)-3,5,8a-trimethyl-4h,4ah,5h,9h-naphtho[2,3-b]furan-8-one

C15H18O2 (230.1306728)


   

3,6-dimethyl-10-methylidene-5h,6h,7h,11h-cyclodeca[b]furan-4-one

3,6-dimethyl-10-methylidene-5h,6h,7h,11h-cyclodeca[b]furan-4-one

C15H18O2 (230.1306728)


   

2-(3,8-dimethyl-5,6-dihydroazulen-5-yl)propanoic acid

2-(3,8-dimethyl-5,6-dihydroazulen-5-yl)propanoic acid

C15H18O2 (230.1306728)


   

1-hydroxy-5,5-dimethyl-1-phenylhepta-1,6-dien-3-one

1-hydroxy-5,5-dimethyl-1-phenylhepta-1,6-dien-3-one

C15H18O2 (230.1306728)


   

5,8,8-trimethyl-3h,4h,7h,9h-azuleno[4,5-c]furan-1-one

5,8,8-trimethyl-3h,4h,7h,9h-azuleno[4,5-c]furan-1-one

C15H18O2 (230.1306728)


   

(3r,3as,9as,9bs)-3,6-dimethyl-9-methylidene-3h,3ah,4h,5h,9ah,9bh-azuleno[4,5-b]furan-2-one

(3r,3as,9as,9bs)-3,6-dimethyl-9-methylidene-3h,3ah,4h,5h,9ah,9bh-azuleno[4,5-b]furan-2-one

C15H18O2 (230.1306728)


   

(4ar,5s)-3,4a,5-trimethyl-4h,5h,6h,7h-naphtho[2,3-b]furan-2-one

(4ar,5s)-3,4a,5-trimethyl-4h,5h,6h,7h-naphtho[2,3-b]furan-2-one

C15H18O2 (230.1306728)


   

5-[(2s)-1-hydroxypropan-2-yl]-3,8-dimethylnaphthalen-2-ol

5-[(2s)-1-hydroxypropan-2-yl]-3,8-dimethylnaphthalen-2-ol

C15H18O2 (230.1306728)


   

(2e)-dec-2-en-4,6-diyn-1-yl 3-methylbut-2-enoate

(2e)-dec-2-en-4,6-diyn-1-yl 3-methylbut-2-enoate

C15H18O2 (230.1306728)


   

(2's,6r)-2',3,5-trimethylspiro[1-benzofuran-6,1'-cyclopentan]-2-one

(2's,6r)-2',3,5-trimethylspiro[1-benzofuran-6,1'-cyclopentan]-2-one

C15H18O2 (230.1306728)


   

(8s)-1,5,8-trimethyl-6h,7h,9h-naphtho[2,1-b]furan-8-ol

(8s)-1,5,8-trimethyl-6h,7h,9h-naphtho[2,1-b]furan-8-ol

C15H18O2 (230.1306728)


   

4-[(2s)-6-methyl-4-oxohept-5-en-2-yl]benzaldehyde

4-[(2s)-6-methyl-4-oxohept-5-en-2-yl]benzaldehyde

C15H18O2 (230.1306728)


   

1,5,8-trimethyl-4h,5h,5ah,6h,9ah-naphtho[2,1-b]furan-7-one

1,5,8-trimethyl-4h,5h,5ah,6h,9ah-naphtho[2,1-b]furan-7-one

C15H18O2 (230.1306728)


   

(4ar,5s)-3,4a,5-trimethyl-4h,5h,6h,7h-naphtho[2,3-b]furan-8-one

(4ar,5s)-3,4a,5-trimethyl-4h,5h,6h,7h-naphtho[2,3-b]furan-8-one

C15H18O2 (230.1306728)


   

(1r,3r,7r,9r,10s,12r)-9-methyl-4,13-dimethylidene-6-oxatetracyclo[7.4.0.0³,⁷.0¹⁰,¹²]tridecan-5-one

(1r,3r,7r,9r,10s,12r)-9-methyl-4,13-dimethylidene-6-oxatetracyclo[7.4.0.0³,⁷.0¹⁰,¹²]tridecan-5-one

C15H18O2 (230.1306728)


   

3,6,9-trimethyl-4h,5h,7h,9ah,9bh-azuleno[4,5-b]furan-2-one

3,6,9-trimethyl-4h,5h,7h,9ah,9bh-azuleno[4,5-b]furan-2-one

C15H18O2 (230.1306728)


   

2,6,12-trimethyl-8-oxatricyclo[7.4.0.0²,⁶]trideca-1(13),9,11-trien-7-one

2,6,12-trimethyl-8-oxatricyclo[7.4.0.0²,⁶]trideca-1(13),9,11-trien-7-one

C15H18O2 (230.1306728)