Exact Mass: 221.191
Exact Mass Matches: 221.191
Found 251 metabolites which its exact mass value is equals to given mass value 221.191,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Procarbazine
Procarbazine is only found in individuals that have used or taken this drug. It is an antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkins disease. [PubChem]The precise mode of cytotoxic action of procarbazine has not been clearly defined. There is evidence that the drug may act by inhibition of protein, RNA and DNA synthesis. Studies have suggested that procarbazine may inhibit transmethylation of methyl groups of methionine into t-RNA. The absence of functional t-RNA could cause the cessation of protein synthesis and consequently DNA and RNA synthesis. In addition, procarbazine may directly damage DNA. Hydrogen peroxide, formed during the auto-oxidation of the drug, may attack protein sulfhydryl groups contained in residual protein which is tightly bound to DNA. L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01X - Other antineoplastic agents > L01XB - Methylhydrazines C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C2842 - DNA Binding Agent D000970 - Antineoplastic Agents
Dioscorine
Dioscorine is found in root vegetables. Dioscorine is an alkaloid from the tubers of wild yam Dioscorea hispid
N-Isobutyl-2,4,8-decatrienamide
N-Isobutyl-2,4,8-decatrienamide is found in herbs and spices. N-Isobutyl-2,4,8-decatrienamide is an alkaloid from the roots of Achillea millefolium (yarrow Alkaloid from the roots of Achillea millefolium (yarrow). N-Isobutyl-2,4,8-decatrienamide is found in herbs and spices.
Sarmentine
Constituent of fruits of pepper (Piper nigrum) and cha-plu (Piper sarmentosum) (Piperaceae). Sarmentine is found in herbs and spices and pepper (spice). Sarmentine is found in herbs and spices. Sarmentine is a constituent of fruits of pepper (Piper nigrum) and cha-plu (Piper sarmentosum) (Piperaceae).
N-3,7-Dimethyl-2,6-octadienylcyclopropylcarboxamide
N-3,7-Dimethyl-2,6-octadienylcyclopropylcarboxamide is used as a food additive [EAFUS] ("EAFUS: Everything Added to Food in the United States. [http://www.eafus.com/]") It is used as a food additive .
N,N,O-Tridesmethyltramadol
N,N,O-Tridesmethyltramadol is a metabolite of tramadol. Tramadol hydrochloride (trademarked as Conzip, Ryzolt, Ultracet, Ultram in the USA; Ralivia and Zytram XL in Canada) is a centrally-acting synthetic analgesic used to treat moderate to moderately-severe pain. The drug has a wide range of applications, including treatment of rheumatoid arthritis, restless legs syndrome, and fibromyalgia. It was launched and marketed as Tramal by the German pharmaceutical company Grnenthal GmbH in 1977 (Wikipedia).
N'-(1,6-Dihydro-6-oxo-2-pyridinyl)-N,N-dipropylmethanimidamide
Ibuproxam
M - Musculo-skeletal system > M01 - Antiinflammatory and antirheumatic products > M01A - Antiinflammatory and antirheumatic products, non-steroids > M01AE - Propionic acid derivatives C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics D000893 - Anti-Inflammatory Agents D018501 - Antirheumatic Agents
[R-(R*,R*)]-alpha,4-Dimethyl-alpha-(4-methyl-3-pentenyl)-3-cyclohexene-1-methanamine
Aminobisabolene
Mexiletine acetate
CONFIDENCE Tentative identification: most likely structure (Level 3); INTERNAL_ID 901 INTERNAL_ID 901; CONFIDENCE Tentative identification: most likely structure (Level 3)
4-aminoeudesm-11-ene|4-aminoeudesm-11-ene hydrochloride|rel-(4R,5R,7S,10R)-eudesm-11-en-4-ylamine|rel-(4R,5R,7S,10R)-eudesm-11-en-4-ylamine hydrochloride
5-hydroxy-5((E,E)-6-methyl-2,4-octadienyl)-3-pyrrolin-2-one|Axinellamide
2-ethyl-1,1-dimethyl-1,2,3,4-tetrahydroisoquinoline-6,7-diol
2,6-diisopropenyl-1-methoxy-2,3,5,6-tetrahydro-1H-imidazo[1,2-a]imidazole|Isoalchornein|Isoalchorneine
3-butoxymethyl-5,6,7,8-tetrahydro-8-indolizinone|kinganone
2-[Methyl(2,6-dimethylphenyl)amino]propionic acid methyl ester
1,2,3,4-Tetrahydro-7,8-dimethoxy-1,2-dimethylisoquinoline
1,2,3,4-Tetrahydro-8-hydroxy-6-methoxy-1,2,3-trimethylisoquinoline
procarbazine
L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01X - Other antineoplastic agents > L01XB - Methylhydrazines C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C2842 - DNA Binding Agent D000970 - Antineoplastic Agents
(4R)-4-methyl-5-((Z)-1,2,3,8a-tetrahydroindolizin-6(5H)-ylidene)pentan-2-ol
(5R,8R)-8-ethyl-5-((E)-pent-3-en-1-yl)octahydroindolizine
(5R,8R)-8-ethyl-5-(pent-4-en-1-yl)octahydroindolizine
6,8-dimethyl-5-(pent-4-en-1-yl)octahydroindolizine
6,8-dimethyl-5-pentyl-1,2,3,5,8,8a-hexahydroindolizine
N-3,7-Dimethyl-2,6-octadienylcyclopropylcarboxamide
tapentadol
D018377 - Neurotransmitter Agents > D014179 - Neurotransmitter Uptake Inhibitors > D018759 - Adrenergic Uptake Inhibitors D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D009294 - Narcotics D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents D002491 - Central Nervous System Agents > D000700 - Analgesics N - Nervous system > N02 - Analgesics > N02A - Opioids D049990 - Membrane Transport Modulators
(2S)-3-(Dimethylamino)-1-(3-methoxyphenyl)-2-methyl-1-propanone
Benzoic acid, 4-[(1S)-1-aminoethyl]-, 1,1-dimethylethyl ester
N-[(1S,2S)-1-hydroxy-1-phenylpropan-2-yl]-N-methylpropanamide
1H-Imidazole-1-carboxamide,N-cyclohexyl-2-ethyl-(9CI)
Lithium diisobutyl-tert-butoxyaluMinuM hydride, 0.25 M solution in THF/hexanes
2-[4-(tetrahydro-2H-pyran-2-yloxy)phenyl]ethan-1-amine
(3-aminomethyl-phenyl)-acetic acid tert-butyl ester
2-Methyl-3-[(phenylmethyl)amino]propanoic acid ethyl ester
1H-Pyrrole-3-carboxylicacid,1-cyclohexyl-2,5-dimethyl-(9CI)
(4-(4-METHOXYPHENYL)TETRAHYDRO-2H-PYRAN-4-YL)METHANAMINE
3-(4,4,5,5-tetramethyl-1,3-dioxolan-2-yl)aniline(SALTDATA: FREE)
2-[1-(6-methylpyridazin-3-yl)piperidin-4-yl]ethanol
6-(2-amino-1-hydroxypropan-2-yl)-5,6,7,8-tetrahydronaphthalen-2-ol
(4s,5s)-(+)-2,2-dimethyl-5-methylamino-4-phenyl-1,3-dioxane
(2S,3S)-2-(benzyl(methyl)amino)-3-methylpentan-1-ol
ETHYL 3-[3-(AMINOMETHYL)PHENYL]-2-METHYLPROPIONATE
3-(dimethylamino)-1-(3-methoxyphenyl)-2-methylpropan-1-one
(4-Methoxy-benzyl)-(tetrahydro-furan-2-ylmethyl)-amine
2-tert-butyl-6-[(dimethylamino)methyl]-4-methylphenol
1-acetyl-4-pyrrolidin-1-ylpiperidine-4-carbonitrile(SALTDATA: FREE)
4-(2-Aminoethyl)benzoic acid-1,1-dimethylethyl ester
1-[4-(ETHYLAMINO)-2-HYDROXY-3-PROPYLPHENYL]ETHAN-1-ONE
N-tert-butyl(3,5,6-trimethylpyrazin-2-yl)methanimine N-oxide
ibuproxam
M - Musculo-skeletal system > M01 - Antiinflammatory and antirheumatic products > M01A - Antiinflammatory and antirheumatic products, non-steroids > M01AE - Propionic acid derivatives C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics D000893 - Anti-Inflammatory Agents D018501 - Antirheumatic Agents
N-(1,6-Dihydro-6-oxo-2-pyridinyl)-N,N-dipropylmethanimidamide
2-[(2,6-Dimethylphenyl)amino]-n,n,n-trimethyl-2-oxoethanaminium
3-Phenylpropanoic acid 2-(dimethylamino)ethyl ester
(1S)-N-(1-Phenylethyl)-3-hydroxy-2,2-dimethylpropanamide
1-[(2E,4E)-2,4-decadienoyl]pyrrolidine
A natural product found in Piper boehmeriaefolium.
Cyclopropanecarboxamide, N-((2E)-3,7-dimethyl-2,6-octadien-1-yl)-
JNJ-39758979
JNJ-39758979 is a selective, orally active, and high-affinity histamine H4 receptor antagonist with Kis of 12.5, 5.3, and 25 nM for human, mouse, and monkey histamine H4 receptor, respectively. JNJ-39758979 functionally antagonizes histamine-induced cAMP inhibition with a pA2 of 7.9 in transfected cells. JNJ-39758979 shows good anti-inflammatory and antipruritic activity[1][2].
