3-(1-(dimethylamino)-2-methylpentan-3-yl)phenol (BioDeep_00000387657)
代谢物信息卡片
化学式: C14H23NO (221.178)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(general) 83.33%
分子结构信息
SMILES: CCC(C1=CC(=CC=C1)O)C(C)CN(C)C
InChI: InChI=1S/C14H23NO/c1-5-14(11(2)10-15(3)4)12-7-6-8-13(16)9-12/h6-9,11,14,16H,5,10H2,1-4H3
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- M Giorgi, A Meizler, P C Mills. Quantification of tapentadol in canine plasma by HPLC with spectrofluorimetric detection: development and validation of a new methodology.
Journal of pharmaceutical and biomedical analysis.
2012 Aug; 67-68(?):148-53. doi:
10.1016/j.jpba.2012.04.020. [PMID: 22621882] - Xu Steven Xu, Johan W Smit, Rachel Lin, Kim Stuyckens, Rolf Terlinden, Partha Nandy. Population pharmacokinetics of tapentadol immediate release (IR) in healthy subjects and patients with moderate or severe pain.
Clinical pharmacokinetics.
2010 Oct; 49(10):671-82. doi:
10.2165/11535390-000000000-00000. [PMID: 20818833] - James A Bourland, Ayodele A Collins, Scot A Chester, Sumankalai Ramachandran, Ronald C Backer. Determination of tapentadol (Nucynta®) and N-desmethyltapentadol in authentic urine specimens by ultra-performance liquid chromatography-tandem mass spectrometry.
Journal of analytical toxicology.
2010 Oct; 34(8):450-7. doi:
10.1093/jat/34.8.450. [PMID: 21819789] - Cynthia Coulter, Margaux Taruc, James Tuyay, Christine Moore. Determination of tapentadol and its metabolite N-desmethyltapentadol in urine and oral fluid using liquid chromatography with tandem mass spectral detection.
Journal of analytical toxicology.
2010 Oct; 34(8):458-63. doi:
10.1093/jat/34.8.458. [PMID: 21819790] - Johan W Smit, Charles Oh, Jens Rengelshausen, Rolf Terlinden, Paulien G M Ravenstijn, Shean-Sheng Wang, David Upmalis, Bernhard Mangold. Effects of acetaminophen, naproxen, and acetylsalicylic acid on tapentadol pharmacokinetics: results of two randomized, open-label, crossover, drug-drug interaction studies.
Pharmacotherapy.
2010 Jan; 30(1):25-34. doi:
10.1592/phco.30.1.25. [PMID: 20030470] - Rolf Terlinden, Joachim Ossig, Frank Fliegert, Claudia Lange, Karin Göhler. Absorption, metabolism, and excretion of 14C-labeled tapentadol HCl in healthy male subjects.
European journal of drug metabolism and pharmacokinetics.
2007 Jul; 32(3):163-9. doi:
10.1007/bf03190478. [PMID: 18062408]
