Exact Mass: 157.05613160000001
Exact Mass Matches: 157.05613160000001
Found 500 metabolites which its exact mass value is equals to given mass value 157.05613160000001,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
3-Methylcrotonylglycine
3-Methylcrotonylglycine is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. However, the excretion of certain acyl glycines is increased in several inborn errors of metabolism. In certain cases the measurement of these metabolites in body fluids can be used to diagnose disorders associated with mitochondrial fatty acid beta-oxidation. Acyl glycines are produced through the action of glycine N-acyltransferase (EC 2.3.1.13) which is an enzyme that catalyzes the chemical reaction: acyl-CoA + glycine < -- > CoA + N-acylglycine. 3-Methylcrotonylglycine is a normal amino acid metabolite found in urine. Increased levels of this metabolite are found in patients suffering from leucine catabolic disorders, such as 3-methylcrotonyl-CoA carboxylase deficiency. 3-Methylcrotonylglycine is often considered to be a diagnostic marker of organic acidemias (PMID 11170888). Moreover, 3-methylcrotonylglycine is found to be associated with 3-hydroxy-3-methylglutaryl-CoA lyase deficiency and propionic acidemia, which are also inborn errors of metabolism. 3-Methylcrotonylglycine is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. However, the excretion of certain acyl glycines is increased in several inborn errors of metabolism. In certain cases the measurement of these metabolites in body fluids can be used to diagnose disorders associated with mitochondrial fatty acid beta-oxidation. Acyl glycines are produced through the action of glycine N-acyltransferase (EC 2.3.1.13) which is an enzyme that catalyzes the chemical reaction: 3-Methylcrotonylglycine is an acyl glycine, a normal amino acid metabolite found in urine.
2-Aminomuconic acid
2-Aminomuconic acid is a product of the Tryptophan metabolism degradation pathway (kinurenine pathway), in a reaction catabolized by the enzyme aminocarboxymuconate semialdehyde decarboxylase [EC:4.1.1.45]. The kynurenine pathway is the major route of L-tryptophan degradation in mammals. (BioCyc) [HMDB] 2-Aminomuconic acid is a product of the Tryptophan metabolism degradation pathway (kinurenine pathway), in a reaction catabolized by the enzyme aminocarboxymuconate semialdehyde decarboxylase [EC:4.1.1.45]. The kynurenine pathway is the major route of L-tryptophan degradation in mammals. (BioCyc).
Paramethadione
Paramethadione is only found in individuals that have used or taken this drug. It is an anticonvulsant in the oxazolidinedione class. It is associated with fetal trimethadione syndrome, which is also known as paramethadione syndrome.Dione anticonvulsants such as paramethadione reduce T-type calcium currents in thalamic neurons (including thalamic relay neurons). This inhibits corticothalamic transmission and raises the threshold for repetitive activity in the thalamus. This results in a dampening of the abnormal thalamocortical rhythmicity proposed to underlie the 3-Hz spike-and-wave discharge seen on electroencephalogram (EEG) during absence seizures. N - Nervous system > N03 - Antiepileptics > N03A - Antiepileptics > N03AC - Oxazolidine derivatives C78272 - Agent Affecting Nervous System > C264 - Anticonvulsant Agent
1-nitrosonaphthalene
1-nitrosonaphthalene is considered to be practically insoluble (in water) and basic
Hydroxyethylclavam
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D047090 - beta-Lactams D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007769 - Lactams
ETHADIONE
N - Nervous system > N03 - Antiepileptics > N03A - Antiepileptics > N03AC - Oxazolidine derivatives
Tiglylglycine
Tiglylglycine is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. However, the excretion of certain acyl glycines is increased in several inborn errors of metabolism. In certain cases the measurement of these metabolites in body fluids can be used to diagnose disorders associated with mitochondrial fatty acid beta-oxidation. Acyl glycines are produced through the action of glycine N-acyltransferase (EC 2.3.1.13) which is an enzyme that catalyzes the chemical reaction: acyl-CoA + glycine < -- > CoA + N-acylglycine. Tiglylglycine is an intermediate product of the catabolism of isoleucine. An elevated level of tiglylglycine is identified in urine of patients with beta-ketothiolase deficiency or with disorders of propionate metabolism (PMID 7923765). Tiglyglycine is a biomarker for the consumption of cheese. Tiglylglycine is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. However, the excretion of certain acyl glycines is increased in several inborn errors of metabolism. In certain cases the measurement of these metabolites in body fluids can be used to diagnose disorders associated with mitochondrial fatty acid beta-oxidation. Acyl glycines are produced through the action of glycine N-acyltransferase (EC 2.3.1.13) which is an enzyme that catalyzes the chemical reaction:
N-Acetylproline
N-Acetyl-L-proline or N-Acetylproline, belongs to the class of organic compounds known as N-acyl-alpha amino acids. N-acyl-alpha amino acids are compounds containing an alpha amino acid which bears an acyl group at its terminal nitrogen atom. N-Acetylproline can also be classified as an alpha amino acid or a derivatized alpha amino acid. Technically, N-Acetylproline is a biologically available N-terminal capped form of the proteinogenic alpha amino acid L-proline. N-acetyl amino acids can be produced either via direct synthesis of specific N-acetyltransferases or via the proteolytic degradation of N-acetylated proteins by specific hydrolases. N-terminal acetylation of proteins is a widespread and highly conserved process in eukaryotes that is involved in protection and stability of proteins (PMID: 16465618). About 85\\% of all human proteins and 68\\% of all yeast proteins are acetylated at their N-terminus (PMID: 21750686). Several proteins from prokaryotes and archaea are also modified by N-terminal acetylation. The majority of eukaryotic N-terminal-acetylation reactions occur through N-acetyltransferase enzymes or NAT’s (PMID: 30054468). These enzymes consist of three main oligomeric complexes NatA, NatB, and NatC, which are composed of at least a unique catalytic subunit and one unique ribosomal anchor. The substrate specificities of different NAT enzymes are mainly determined by the identities of the first two N-terminal residues of the target protein. The human NatA complex co-translationally acetylates N-termini that bear a small amino acid (A, S, T, C, and occasionally V and G) (PMID: 30054468). NatA also exists in a monomeric state and can post-translationally acetylate acidic N-termini residues (D-, E-). NatB and NatC acetylate N-terminal methionine with further specificity determined by the identity of the second amino acid. N-acetylated amino acids, such as N-acetylproline can be released by an N-acylpeptide hydrolase from peptides generated by proteolytic degradation (PMID: 16465618). In addition to the NAT enzymes and protein-based acetylation, N-acetylation of free proline can also occur. Many N-acetylamino acids, including N-acetylproline are classified as uremic toxins if present in high abundance in the serum or plasma (PMID: 26317986; PMID: 20613759). Uremic toxins are a diverse group of endogenously produced molecules that, if not properly cleared or eliminated by the kidneys, can cause kidney damage, cardiovascular disease and neurological deficits (PMID: 18287557).
Favipiravir
C5H4FN3O2 (157.02875360000002)
J - Antiinfectives for systemic use > J05 - Antivirals for systemic use > J05A - Direct acting antivirals COVID info from DrugBank, clinicaltrial, clinicaltrials, clinical trial, clinical trials D000890 - Anti-Infective Agents > D000998 - Antiviral Agents C471 - Enzyme Inhibitor > C25995 - RNA Polymerase Inhibitor C254 - Anti-Infective Agent > C281 - Antiviral Agent Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS
(2S)-1,2-Dimethyl-3,4-dioxoazetidine-2-carboxylic acid
2,4-Dimethylquinoline
2,4-dimethylquinoline belongs to quinolines and derivatives class of compounds. Those are compounds containing a quinoline moiety, which consists of a benzene ring fused to a pyrimidine ring to form benzo[b]azabenzene. 2,4-dimethylquinoline is practically insoluble (in water) and a very strong basic compound (based on its pKa). 2,4-dimethylquinoline can be found in tea, which makes 2,4-dimethylquinoline a potential biomarker for the consumption of this food product.
2,6-Dimethylquinoline
2,6-dimethylquinoline belongs to quinolines and derivatives class of compounds. Those are compounds containing a quinoline moiety, which consists of a benzene ring fused to a pyrimidine ring to form benzo[b]azabenzene. 2,6-dimethylquinoline is practically insoluble (in water) and a very strong basic compound (based on its pKa). 2,6-dimethylquinoline can be found in tea, which makes 2,6-dimethylquinoline a potential biomarker for the consumption of this food product. 2,6-Dimethylquinoline belongs to the class of organic compounds known as quinolines and derivatives. Quinolines and derivatives are compounds containing a quinoline moiety, which consists of a benzene ring fused to a pyrimidine ring to form benzo[b]azabenzene. 2,6-Dimethylquinoline is a dimethylated derivative of quinoline. Quinoline is a colourless hygroscopic Liquid with a strong odour.
4,8-Dimethylquinoline
4,8-dimethylquinoline belongs to quinolines and derivatives class of compounds. Those are compounds containing a quinoline moiety, which consists of a benzene ring fused to a pyrimidine ring to form benzo[b]azabenzene. 4,8-dimethylquinoline is practically insoluble (in water) and a very strong basic compound (based on its pKa). 4,8-dimethylquinoline can be found in tea, which makes 4,8-dimethylquinoline a potential biomarker for the consumption of this food product.
N-methylbenzylamine hydrochloride
2-Amino-4-hydroxy-6-heptynoic acid|2-Amino-4-hydroxy-hept-6-yn-carbonsaeure
3-Methyl-Delta2-dihydromuconsaeure-1-amid|5-carbamoyl-4-methyl-pent-4-enoic acid|5-Carbamoyl-4-methyl-pent-4-ensaeure
2,6-Dimethylquinoline
2,6-Dimethylquinoline, a nature constituent from the roots of Peucedantu praeruptorum, is a CYP1A2 inhibitor with an IC50 of 3.3 μM. 2,6-Dimethylquinoline also inhibits CYP2B6 activity with an IC50 of 480 μM[1][2][3]. 2,6-Dimethylquinoline, a nature constituent from the roots of Peucedantu praeruptorum, is a CYP1A2 inhibitor with an IC50 of 3.3 μM. 2,6-Dimethylquinoline also inhibits CYP2B6 activity with an IC50 of 480 μM[1][2][3].
Tiglylglycine
An N-acylglycine that is glycine with an amine hydrogen substituted by a 2-methylbut-2-enoyl (tiglyl) group. Acquisition and generation of the data is financially supported in part by CREST/JST.
3-Methylcrotonylglycine
3-Methylcrotonylglycine is an acyl glycine, a normal amino acid metabolite found in urine.
Ethosuximide M6, 2-(1-Hydroxyethyl)-2-methylsuccinimide
2-amino-muconic acid
A 2-aminomuconic acid in which the two double bonds adopt a 2E,4Z-configuration.
3-Isoxazolecarboximidamide,N-hydroxy-5-(hydroxymethyl)-
Isoxazole, 3,5-dimethyl-4-[(methylthio)methyl]- (9CI)
3-Pyridinecarboxylic acid, 1,2,5,6-tetrahydro-4-hydroxy-, methyl ester (9CI)
1H-Azepine-4-carboxaldehyde, hexahydro-3-hydroxy-2-oxo- (9CI)
1-bromo-1,2,2,3,3,4,4,5,5-nonadeuteriocyclopentane
(2,4-Dimethylthiazol-5-yl)boronic acid
C5H8BNO2S (157.03687779999998)
2,4-Dihydro-5-propoxy-4-methyl-3H-1,2,4-Triazol-3-one
1H-Imidazole-4-carboxylicacid,5-amino-4,5-dihydro-,ethylester(9CI)
4(1H)-Pyrimidinone,6-amino-2,3-dihydro-1-methyl-2-thioxo-
ethyl 4-amino-1,2,5-oxadiazole-3-carboxylate(SALTDATA: FREE)
6-aminodihydro-1,3-dimethyl-2,4(1H,3H) –pyrimidinedione
5-sec-butyl-1,3,4-thiadiazol-2-amine(SALTDATA: FREE)
Pyrazinecarboxamide, 5-fluoro-3,4-dihydro-3-oxo- (9CI)
C5H4FN3O2 (157.02875360000002)
1H-1,2,3-Triazole-5-carboxylicacid,4-methoxy-1-methyl-(9CI)
Cyclopropanecarboxylic acid, 2-[(ethylamino)carbonyl]- (9CI)
1H-Imidazole-1-aceticacid,2-amino-4,5-dihydro-,methylester(9CI)
1H-1,2,4-Triazole-3-carboxylic acid,5-hydrazino-,hydrazide (9CI)
3H-1,2,4-Triazole-3-thione,2,4-dihydro-4-methyl-5-(1-methylethyl)-(9CI)
4-Pyrimidinamine, 5-(chloromethyl)-2-methyl- (9CI)
Chlormequat chloride
D006133 - Growth Substances > D010937 - Plant Growth Regulators
3-(2-oxohydrazinyl)-1H-1,2,4-triazole-5-carboxylic acid
5-(Acetylsulfanyl)-pentanenitrile,S-(4-Cyanobutyl)ethanethioate,Thiolacetylpentanenitrile
Ethanone, 2-chloro-1-(1-methyl-1H-pyrrol-2-yl)- (9CI)
(2S)-3-(3-ACETYL-4-HYDROXYPHENYL)-2-AMINOPROPANOICACID
6,7-Dihydro-5H-Pyrrolo[3,4-D]Pyrimidine Hydrochloride
L-xylo-Hept-4-enonic acid, 2-amino-3,6-anhydro-2,4,5,7-tetradeoxy-
Favipiravir
C5H4FN3O2 (157.02875360000002)
J - Antiinfectives for systemic use > J05 - Antivirals for systemic use > J05A - Direct acting antivirals COVID info from DrugBank, clinicaltrial, clinicaltrials, clinical trial, clinical trials D000890 - Anti-Infective Agents > D000998 - Antiviral Agents C471 - Enzyme Inhibitor > C25995 - RNA Polymerase Inhibitor C254 - Anti-Infective Agent > C281 - Antiviral Agent Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS
(4S,5S)-5-hydroxy-4-(hydroxymethyl)-6-oxocyclohex-1-en-1-olate
O2-Vinyl 1-(Pyrrolidin-1-yl)diazen-1-ium-1,2-diolate
paramethadione (500 mg)
N - Nervous system > N03 - Antiepileptics > N03A - Antiepileptics > N03AC - Oxazolidine derivatives C78272 - Agent Affecting Nervous System > C264 - Anticonvulsant Agent
(S)-Dihydroorotate
A dihydroorotate that is the conjugate base of (S)-dihydroorotic acid.
furanomycin
A non-proteinogenic L-alpha-amino acid that is L-alanine in which the methyl group is replaced by a (2R,5S)-5-methyl-2,5-dihydrofuran-2-yl moiety.
(2Z,4E)-2-aminomuconic acid
A 2-aminomuconic acid in which the two double bonds adopt a 2Z,4E-configuration.
3-Methylcrotonyl glycine
An N-acylglycine in which the acyl group is specified as 3-methylbut-2-enoyl.