Exact Mass: 1202.7996859999998
Exact Mass Matches: 1202.7996859999998
Found 19 metabolites which its exact mass value is equals to given mass value 1202.7996859999998
,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Polymyxin B Sulfate
Polymyxin B sulfate is a mixture of polymyxins B1 and B2, obtained from Bacillus polymyxa strains. They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes. Polymyxin B is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic. All gram-positive bacteria, fungi, and the gram-negative cocci, N. gonorrhea and N. menigitidis, are resistant. It is appropriate for treatment of infections of the urinary tract, meninges, and blood stream, caused by susceptible strains of Pseudomonas aeruginosa. D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D011113 - Polymyxins D000890 - Anti-Infective Agents > D023181 - Antimicrobial Cationic Peptides
Ganglioside GA2 (d18:1/26:1(17Z))
C64H118N2O18 (1202.8379208000001)
Ganglioside GA2 (d18:1/26:1(17Z)) is a glycosphingolipid (ceramide and oligosaccharide)or oligoglycosylceramide with one or more sialic acids (i.e. n-acetylneuraminic acid) linked on the sugar chain. It is a component the cell plasma membrane which modulates cell signal transduction events. Gangliosides have been found to be highly important in immunology. Ganglioside GA2 carries a net-negative charge at pH 7.0 and is acidic. Gangliosides can amount to 6\\% of the weight of lipids from brain, but they are found at low levels in all animal tissues. Gangliosides are glycosphingolipids. There are four types of glycosphingolipids, the cerebrosides, sulfatides, globosides and gangliosides. Gangliosides are very similar to globosides except that they also contain N-acetyl neuraminic acid (NANA) in varying amounts. The specific names for the gangliosides provide information about their structure. The letter G refers to ganglioside, and the subscripts M, D, T and Q indicate that the molecule contains mono-, di-, tri and quatra-sialic acid. The numbered subscripts 1, 2 and 3 refer to the carbohydrate sequence that is attached to the ceramide. In particular, 1 stands for GalGalNAcGalGlc-ceramide, 2 stands for GalNAcGalGlc-ceramide and 3 stands for GalGlc-ceramide. Deficiencies in lysosomal enzymes that degrade the carbohydrate portions of various gangliosides are responsible for a number of lysosomal storage diseases such as Tay-Sachs disease, Sandhoff disease, and GM1 gangliosidosis. The carbohydrate portion of the ganglioside GM1 is the site of attachment of cholera toxin, the protein secreted by Vibrio cholerae.
Polymyxin B1
A polymyxin having a (6R)-6-methyloctanoyl group at the amino terminus. Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment[1][2].
GalNAcbeta1-4Galbeta1-4Glcbeta-Cer(d18:1/26:1(17Z))
C64H118N2O18 (1202.8379208000001)
Ganglioside GA2 (d18:1/26:1(17Z))
C64H118N2O18 (1202.8379208000001)
Polymyxin B sulfate
Hex(2)-HexNAc-Cer 44:2;O2
C64H118N2O18 (1202.8379208000001)
Hex-HexNAc-Cer 44:2;O2
C64H118N2O18 (1202.8379208000001)