Classification Term: 771

Oxanes (ontology term: CHEMONTID:0002012)

Compounds containing an oxane (tetrahydropyran) ring, which is a six-member saturated aliphatic heterocycle with one oxygen atom and five carbon atoms." []

found 33 associated metabolites at class metabolite taxonomy ontology rank level.

Ancestor: Organoheterocyclic compounds

Child Taxonomies: There is no child term of current ontology term.

Eucalyptol

(1s,4s)-1,3,3-trimethyl-2-oxabicyclo[2.2.2]octane

C10H18O (154.1357578)


Eucalyptol is an organic compound that is a colourless liquid. It is a cyclic ether and a monoterpene. Eucalyptol is a natural constituent of a number of aromatic plants and their essential oil fraction. Eucalyptol was given GRAS (Generally Recognized As Safe) status by the Flavor and Extract Manufacturers Association FEMA, 1965 and is approved by the Food and Drug Administration for food use. 1,8-Dihydroxy-10-carboxy-p-menthane, 2-hydroxy-cineole, and 3-hydroxy-cineole are the main metabolites of eucalyptol. Toxicological data available on eucalyptol are rather limited. Following accidental exposure, death was reported in two cases after ingestion of 3.5-5 mL of essential eucalyptus oil, but a number of recoveries have also been described for much higher amounts of oil. In a 1994 report released by five top cigarette companies, eucalyptol was listed as one of the 599 additives to cigarettes. It is usually added to improve the flavour (PMID:12048025). R - Respiratory system > R05 - Cough and cold preparations > R05C - Expectorants, excl. combinations with cough suppressants > R05CA - Expectorants COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials C78273 - Agent Affecting Respiratory System > C74536 - Mucolytic Agent D019141 - Respiratory System Agents > D000996 - Antitussive Agents D000074385 - Food Ingredients > D005503 - Food Additives D010592 - Pharmaceutic Aids > D005421 - Flavoring Agents D010575 - Pesticides > D007302 - Insect Repellents D003358 - Cosmetics > D009067 - Mouthwashes D001697 - Biomedical and Dental Materials D002491 - Central Nervous System Agents D000890 - Anti-Infective Agents D020011 - Protective Agents D016573 - Agrochemicals D012997 - Solvents Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS

   

2-Exo-hydroxy-1,8-cineole

(1R,4S,6S)-1,3,3-trimethyl-2-oxabicyclo[2.2.2]octan-6-ol

C10H18O2 (170.1306728)


2-exo-hydroxy-1,8-cineole is part of the Steroid hormone biosynthesis, Linoleic acid metabolism, Retinol metabolism, and Bile secretion pathways. It is a substrate for: Cytochrome P450 3A4.

   

D-1,5-Anhydrofructose

4,5-dihydroxy-6-(hydroxymethyl)oxan-3-one

C6H10O5 (162.052821)


D-1,5-Anhydrofructose is found in fruits. D-1,5-Anhydrofructose is isolated from Morchella vulgaris (morel). Isolated from Morchella vulgaris (morel). D-1,5-Anhydrofructose is found in fruits.

   

Daucol

5,8-dimethyl-2-(propan-2-yl)-11-oxatricyclo[6.2.1.0¹,⁵]undecan-7-ol

C15H26O2 (238.1932696)


Constituent of carrot (Daucus carota) seed oil. Daucol is found in wild carrot, root vegetables, and carrot. Daucol is found in carrot. Daucol is a constituent of carrot (Daucus carota) seed oil.

   

Heptachlor exo-epoxide

1,6,8,9,10,11,11-heptachloro-4-oxatetracyclo[6.2.1.0²,⁷.0³,⁵]undec-9-ene

C10H5Cl7O (385.816009)


D010575 - Pesticides > D007306 - Insecticides D016573 - Agrochemicals

   

alpha-Bisabolol oxide A

2,2,6-trimethyl-6-(4-methylcyclohex-3-en-1-yl)oxan-3-ol

C15H26O2 (238.1932696)


Constituent of Matricaria chamomilla (German chamomile). alpha-Bisabolol oxide A is found in many foods, some of which are herbs and spices, fats and oils, tea, and german camomile. alpha-Bisabolol oxide A is found in fats and oils. alpha-Bisabolol oxide A is a constituent of Matricaria chamomilla (German chamomile). Bisabolol oxide A possesses antihyperalgesic and antiedematous effects with oral activity[1].

   

exo,exo-1,8-Epoxy-p-menthane-2,6-diol

1,8-Epoxy-1-methyl-4-isopropylcyclohexane-2,6-diol

C10H18O3 (186.1255878)


exo,exo-1,8-Epoxy-p-menthane-2,6-diol is found in herbs and spices. exo,exo-1,8-Epoxy-p-menthane-2,6-diol is a constituent of Foeniculum vulgare (fennel). A - Alimentary tract and metabolism > A05 - Bile and liver therapy > A05B - Liver therapy, lipotropics > A05BA - Liver therapy Constituent of Foeniculum vulgare (fennel). exo,exo-1,8-Epoxy-p-menthane-2,6-diol is found in herbs and spices. D005765 - Gastrointestinal Agents > D002756 - Cholagogues and Choleretics

   

Oxychlordane

1 alpha,2 beta,4 beta,5,6,7 beta,8,8-octachloro-2,3 alpha-Epoxy-3a alpha,4,7,7a alpha-tetrahydro-4,7-methanoindan

C10H4Cl8O (419.77703740000004)


Oxychlordane is a Organochlorine compound, one of the most common chlordane-related environmental contaminants. It is the major metabolite of the cis-chlordane and trans-chlordane. Oxychlordane is considerably more toxic than the parent compound. [PMID: 4755836] There is a dose-response relations between serum cencetrations of oxychlordane and the prevalence of diabetes. [PMID: 16801591].

   

2-Hydroxycineol

1,3,3-trimethyl-2-oxabicyclo[2.2.2]octan-6-ol

C10H18O2 (170.1306728)


2-Hydroxycineol belongs to the family of Oxanes. These are compounds containing an oxane(tetrahydropyran) ring, which is a six-member saturated aliphatic heterocycle with one oxygen atom and five carbon atoms.

   

Rose oxide

4-Methyl-2-(2-methylprop-1-en-1-yl)tetrahydro-2H-pyran

C10H18O (154.1357578)


Flavouring ingredient. Rose oxide is found in many foods, some of which are peppermint, ginger, lemon balm, and black elderberry. Rose oxide is found in black elderberry. Rose oxide is a flavouring ingredien

   

Chrycorin

3,4,7,7a-tetrahydro-5-(2-Thienyl)cyclopenta[b]pyran-6(2H)-one, 9ci

C12H12O2S (220.0557972)


Chrycorin is found in herbs and spices. Chrycorin is isolated from Chrysanthemum coronarium (chop-suey greens Isolated from Chrysanthemum coronarium (chop-suey greens). Chrycorin is found in herbs and spices.

   

Linaloyl oxide

2-ethenyltetrahydro-2,6,6-Trimethylpyran, 9ci

C10H18O (154.1357578)


Linaloyl oxide is found in alcoholic beverages. Linaloyl oxide is a flavouring and fragrence ingredient. Linaloyl oxide is present in roselle tea, muscat grapes, lime oil, alfalfa, Riesling wine, grapefruit, yellow passion fruit, apricot, blackberry, blueberry, nectarine, cherimoya, papaya and curuba fruits. Dehydroxylinalool 3,7-oxide is a flavouring and fragrence ingredient. It is found in roselle tea, muscat grapes, lime oil, alfalfa, riesling wine, grapefruit, yellow passion fruit, apricot, blackberry, blueberry, nectarine, cherimoya, papaya and curuba fruits.

   

Epoxyeremopetasinorol

1-(3-hydroxy-1b,2-dimethyl-2,3,4,5,5a,6-hexahydro-1aH-indeno[1,2-b]oxiren-6a-yl)ethanone

C13H20O3 (224.14123700000002)


Epoxyeremopetasinorol is found in green vegetables. Epoxyeremopetasinorol is a constituent of Petasites japonicus (sweet coltsfoot)

   

Linalool oxide (trans-pyranoid)

6-Ethenyltetrahydro-2,2,6-trimethyl-(3R,6S)-rel-2H-pyran-3-ol

C10H18O2 (170.1306728)


Linalool oxide (trans-pyranoid) is found in tea. This is the trans form of pyranoid linalool oxide, also called Linalool oxide C or Linalool oxide IV; there are 2 possible stereo-isomers

   

alpha-Bisabolol oxide C

1,3-dimethyl-3-(4-methylpent-3-en-1-yl)-2-oxabicyclo[2.2.2]octan-6-ol

C15H26O2 (238.1932696)


Constituent of Matricaria chamomilla (German chamomile). alpha-Bisabolol oxide C is found in many foods, some of which are herbs and spices, fats and oils, german camomile, and tea. alpha-Bisabolol oxide C is found in fats and oils. alpha-Bisabolol oxide C is a constituent of Matricaria chamomilla (German chamomile).

   

5,8-Epoxydaucane

5,8-dimethyl-2-(propan-2-yl)-11-oxatricyclo[6.2.1.0¹,⁵]undecane

C15H26O (222.1983546)


Constituent of carrot Daucus carota. 5,8-Epoxydaucane is found in wild carrot, root vegetables, and carrot. 5,8-Epoxydaucane is found in carrot. 5,8-Epoxydaucane is a constituent of carrot Daucus carota.

   

(1S,2S,4S,5R)-1,8-Epoxy-p-menthane-2,5-diol

1,3,3-trimethyl-2-oxabicyclo[2.2.2]octane-5,7-diol

C10H18O3 (186.1255878)


(1S,2R,4S,5R)-1,8-Epoxy-p-menthane-2,5-diol is found in herbs and spices. (1S,2R,4S,5R)-1,8-Epoxy-p-menthane-2,5-diol is a constituent of Foeniculum vulgare (fennel). Constituent of Foeniculum vulgare (fennel). (1S,2S,4S,5R)-1,8-Epoxy-p-menthane-2,5-diol is found in herbs and spices.

   

Sesquicineol

1,3-dimethyl-3-(4-methylpent-3-en-1-yl)-2-oxabicyclo[2.2.2]octane

C15H26O (222.1983546)


Sesquicineol is a constituent of Boronia megastigma (brown boronia). Constituent of Boronia megastigma (brown boronia)

   

Oryzalic acid A

2-[5-(carboxymethyl)-5,10-dimethyl-11-oxatetracyclo[7.3.1.0¹,⁶.0¹⁰,¹²]tridecan-4-yl]-2-methylpropanoic acid

C20H30O5 (350.209313)


Oryzalic acid A is found in cereals and cereal products. Oryzalic acid A is isolated from rice leaves. Isolated from rice leaves. Oryzalic acid A is found in cereals and cereal products.

   

Hovenitin I

2-(3,4-dihydroxy-5-methoxyphenyl)-3,5,7-trihydroxy-3,4-dihydro-2H-1-benzopyran-4-one

C16H14O8 (334.0688644)


Hovenitin II is a constituent of the seeds and fruit of Hovenia dulcis (raisin tree). Constituent of the seeds and fruit of Hovenia dulcis (raisin tree).

   

Linalool oxide III

2H-Pyran-3-ol, tetrahydro-2,2,6-trimethyl-6-vinyl-, cis- (8ci)

C10H18O2 (170.1306728)


Linalool oxide III is found in tea. This is the cis form of pyranoid linalool oxide, also called Linalool oxide D or Linalool oxide III; there are 2 possible stereo-isomers Synthetic [CCD]

   

Cnidiol C

6-Ethenyl-3,4,5,6-tetrahydro-2,2,6-trimethyl-2H-pyran-3-ol

C10H18O2 (170.1306728)


Cnidiol C is found in citrus. Cnidiol C is a constituent of Citrus species.This is the pyranoid form of linalool oxide; there are 4 possible stereo-isomers Constituent of Citrus subspecies

   

Clarycet

4-Methyl-2-propyloxan-4-yl acetic acid

C11H20O3 (200.14123700000002)


Clarycet is a fragrance ingredient with a fruity arom Fragrance ingredient with a fruity aroma

   

Epoxycampholenic aldehyde

1,2,2-Trimethyl-6-oxabicyclo[3.1.0]hexane-3-acetaldehyde, 9ci

C10H16O2 (168.1150236)


Epoxycampholenic aldehyde is found in fruits. Epoxycampholenic aldehyde is a constituent of Juniperus communis (juniper) Constituent of Juniperus communis (juniper). Epoxycampholenic aldehyde is found in fruits.

   

Tetrahydro-2,5-dimethyl-2H-pyranmethanol

2H-Pyran-2-methanol,tetrahydro-2,5-dimethyl-

C8H16O2 (144.1150236)


Tetrahydro-2,5-dimethyl-2H-pyranmethanol belongs to the class of organic compounds known as oxanes. These are compounds containing an oxane (tetrahydropyran) ring, which is a six-member saturated aliphatic heterocycle with one oxygen atom and five carbon atoms.

   

(2R,3S)-2-Octyl-3-pentyloxane

(2R,3S)-2-Octyl-3-pentyloxane

C18H36O (268.2766006)


   

(2R,3R,4R,5S)-2-Methyl-tetrahydro-pyran-3,4,5-triol

(2R,3R,4R,5S)-2-Methyl-tetrahydro-pyran-3,4,5-triol

C6H12O4 (148.0735552)


   

[(2S,3S,4S,5S,6R)-4,5-Dihydroxy-2,6-dimethyloxan-3-yl] hydrogen sulfate

[(2S,3S,4S,5S,6R)-4,5-Dihydroxy-2,6-dimethyloxan-3-yl] hydrogen sulphuric acid

C7H14O7S (242.0460214)


   

Hymenoxon

12,14-dihydroxy-1,9-dimethyl-4-methylidene-6,13-dioxatricyclo[8.4.0.0³,⁷]tetradecan-5-one

C15H22O5 (282.1467162)


   

N-[(2R,3R,4S,6R)-4,6-Dihydroxy-6-methyl-2-[(1R,2R)-1,2,3-trihydroxypropyl]oxan-3-yl]acetamide

N-[(2R,3R,4S,6R)-4,6-Dihydroxy-6-methyl-2-[(1R,2R)-1,2,3-trihydroxypropyl]oxan-3-yl]acetamide

C11H21NO7 (279.13179560000003)


   

Oxane

Pentamethylene oxide

C5H10O (86.07316100000001)


   

1,5-Cineole

(1S,5S)-1-methyl-4-(propan-2-yl)-6-oxabicyclo[3.1.1]heptane

C10H18O (154.1357578)


1,5-cineole is a member of the class of compounds known as oxanes. Oxanes are compounds containing an oxane (tetrahydropyran) ring, which is a six-member saturated aliphatic heterocycle with one oxygen atom and five carbon atoms. 1,5-cineole is practically insoluble (in water) and an extremely weak basic (essentially neutral) compound (based on its pKa). 1,5-cineole can be found in dill, which makes 1,5-cineole a potential biomarker for the consumption of this food product.

   

cis-tetrahydro-4-methyl-2-(2-methyl-1-propenyl)-2H-pyran

(2R,4S)-(+)-4-Methyl-2-(2-methylprop-1-en-1-yl)tetrahydro-2H-pyran

C10H18O (154.1357578)


Flavouring compound [Flavornet]