Classification Term: 3442

Acetanilides (ontology term: CHEMONTID:0001846)

Organic compounds containing an acetamide group conjugated to a phenyl group." []

found 22 associated metabolites at category metabolite taxonomy ontology rank level.

Phenacetin

N-(4-ethoxyphenyl)acetamide

CONFIDENCE standard compound; INTERNAL_ID 800; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7488; ORIGINAL_PRECURSOR_SCAN_NO 7485 CONFIDENCE standard compound; INTERNAL_ID 800; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7488; ORIGINAL_PRECURSOR_SCAN_NO 7486 CONFIDENCE standard compound; INTERNAL_ID 800; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7450; ORIGINAL_PRECURSOR_SCAN_NO 7449 CONFIDENCE standard compound; INTERNAL_ID 800; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7440; ORIGINAL_PRECURSOR_SCAN_NO 7439 CONFIDENCE standard compound; INTERNAL_ID 800; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7504; ORIGINAL_PRECURSOR_SCAN_NO 7499 CONFIDENCE standard compound; INTERNAL_ID 800; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7480; ORIGINAL_PRECURSOR_SCAN_NO 7478 N - Nervous system > N02 - Analgesics > N02B - Other analgesics and antipyretics > N02BE - Anilides D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics [Raw Data] CBA18_Phenacetin_pos_40eV_1-10_01_709.txt [Raw Data] CBA18_Phenacetin_pos_20eV_1-10_01_707.txt [Raw Data] CBA18_Phenacetin_pos_10eV_1-10_01_706.txt [Raw Data] CBA18_Phenacetin_pos_50eV_1-10_01_710.txt [Raw Data] CBA18_Phenacetin_pos_30eV_1-10_01_708.txt

Practolol

N-[4-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]acetamide

C14H22N2O3 (266.163)

Practolol is only found in individuals that have used or taken this drug. It is a beta-adrenergic antagonist that has been used in the emergency treatment of cardiac arrhythmias. [PubChem]Like other beta-adrenergic antagonists, practolol competes with adrenergic neurotransmitters such as catecholamines for binding at sympathetic receptor sites. Like propranolol and timolol, practolol binds at beta(1)-adrenergic receptors in the heart and vascular smooth muscle, inhibiting the effects of the catecholamines epinephrine and norepinephrine and decreasing heart rate, cardiac output, and systolic and diastolic blood pressure. C - Cardiovascular system > C07 - Beta blocking agents > C07A - Beta blocking agents > C07AB - Beta blocking agents, selective C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C72900 - Adrenergic Antagonist D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D018674 - Adrenergic Antagonists D002317 - Cardiovascular Agents > D000889 - Anti-Arrhythmia Agents Same as: D05587 Practolol is a potent and selective β1-adrenergic receptor antagonist. Practolol can be used for the research of cardiac arrhythmias[1][2][3].

4-Acetamido-2-amino-6-nitrotoluene

N-(3-amino-4-methyl-5-nitrophenyl)ethanimidic acid

C9H11N3O3 (209.08)

This compound belongs to the family of Nitrobenzenes. These are compounds containing a nitrobenzene moiety, which consists of a benzene ring with a carbon bearing a nitro group.

2'-Hydroxyacetanilide

N-(2-hydroxyphenyl)ethanimidic acid

C8H9NO2 (151.0633)

2-Hydroxyacetanilide, also known as N-(2-hydroxyphenyl)acetamide (HPAA), belongs to the class of organic compounds known as aminophenols. These are organic compounds containing an amino group attached to a phenol. HPAA is a benzoxazinoid metabolite. It is a potential urinary biomarker of whole grain intake (PMID: 27805021).

N-Acetyl-2,6-diethylaniline

N-(2,6-Diethylphenyl)ethanimidate

C12H17NO (191.131)

Soil degradation production of Alachlor DKW79-G. Soil degradation produced of Alachlor DKW79-G.

OP-1118

(2R,3S,4S,5S,6R)-6-{[(3E,5E,8S,9E,11S,12R,13E,15E,18S)-11-ethyl-8-hydroxy-18-[(1R)-1-hydroxyethyl]-9,13,15-trimethyl-2-oxo-12-{[(2R,3S,4S,5S)-3,4,5-trihydroxy-6,6-dimethyloxan-2-yl]oxy}-1-oxacyclooctadeca-3,5,9,13,15-pentaen-3-yl]methoxy}-4-hydroxy-5-methoxy-2-methyloxan-3-yl 3,5-dichloro-2-ethyl-4,6-dihydroxybenzoate

C48H68Cl2O17 (986.3833)

OP-1118 is a metabolite of fidaxomicin. Fidaxomicin (trade name Dificid, and previously OPT-80 and PAR-101) is the first in a new class of narrow spectrum macrocyclic antibiotic drugs. It is a fermentation product obtained from the actinomycete Dactylosporangium aurantiacum subspecies hamdenesis. (Wikipedia)

OR-1896

N-{4-[(4R)-4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl]phenyl}acetamide

C13H15N3O2 (245.1164)

OR-1896 is a metabolite of levosimendan. Levosimendan is a calcium sensitiser used in the management of acutely decompensated congestive heart failure. It is marketed under the trade name Simdax. (Wikipedia)

Acetamide, N-[4-[[(aminothioxomethyl)hydrazono]methyl]phenyl]-

N-{4-[({[thio(carbonoimidyl)]amino}imino)methyl]phenyl}ethanimidate

C10H12N4OS (236.0732)

3-(4-Acetamidophenoxy)-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide

3-(4-acetamidophenoxy)-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide

C19H18F3N3O6 (441.1148)

Metacetamol

N-(3-hydroxyphenyl)ethanimidic acid

C8H9NO2 (151.0633)

D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent D002491 - Central Nervous System Agents > D000700 - Analgesics

Acetylfentanyl

N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]acetamide

C21H26N2O (322.2045)

Acedapsone

N-[4-(4-acetamidobenzenesulfonyl)phenyl]acetamide

C16H16N2O4S (332.0831)

D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007917 - Leprostatic Agents C254 - Anti-Infective Agent > C849 - Sulfone Anti-Infective Agent

N-[4-(4-Methyl-6-oxo-4,5-dihydro-1H-pyridazin-3-yl)phenyl]acetamide

N-[4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl]acetamide

C13H15N3O2 (245.1164)

Diamfenetide

N-{4-[2-(2-{4-[(1-hydroxyethylidene)amino]phenoxy}ethoxy)ethoxy]phenyl}ethanimidic acid

C20H24N2O5 (372.1685)

D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000871 - Anthelmintics C254 - Anti-Infective Agent > C276 - Antiparasitic Agent > C250 - Antihelminthic Agent

Monoacetyldapsone hydroxylamine

N-{4-[4-(hydroxyamino)benzenesulfonyl]phenyl}acetamide

C14H14N2O4S (306.0674)

2'-Nitroacetanilide

N-(2-nitrophenyl)acetamide

C8H8N2O3 (180.0535)

N-(4-Methoxyphenyl)acetamide

N-(4-Methoxyphenyl)acetic acid amide

C9H11NO2 (165.079)

N-phenylacetohydrazide

C8H10N2O (150.0793)

3-(5-Acetamido-2-hydroxyphenyl)sulfanyl-2-oxopropanoic acid

3-({2-hydroxy-5-[(1-hydroxyethylidene)amino]phenyl}sulphanyl)-2-oxopropanoic acid

C11H11NO5S (269.0358)

rac S 33138

N-[4-(2-{12-cyano-8-oxa-4-azatricyclo[7.4.0.0^{2,6}]trideca-1(9),10,12-trien-4-yl}ethyl)phenyl]acetamide

C22H23N3O2 (361.179)

5-(4-Acetamidophenyl)pyrazin-2(1H)-one

N-[4-(5-oxo-5,6-Dihydropyrazin-2-yl)phenyl]ethanimidate

C12H11N3O2 (229.0851)

D020011 - Protective Agents > D002316 - Cardiotonic Agents D002317 - Cardiovascular Agents

m-Methyl acetophenone

Sodium N-(3-arsonophenyl)ethanecarboximidic acid

C8H9AsNNaO4 (280.9645)

M-methyl acetophenone is soluble (in water) and a weakly acidic compound (based on its pKa). M-methyl acetophenone can be found in pepper (spice), which makes M-methyl acetophenone a potential biomarker for the consumption of this food product.