Classification Term: 168905

Anisoles (ontology term: 5ca1f875bdcb203d38f14e4ccb4b8fd4)

found 15 associated metabolites at sub_class metabolite taxonomy ontology rank level.

Ancestor: Phenols

Child Taxonomies: There is no child term of current ontology term.

Trimethoprim

5-[(3,4,5-Trimethoxyphenyl)methyl]-2,4-pyrimidinediamine

C14H18N4O3 (290.1378838)


A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to pyrimethamine. The interference with folic acid metabolism may cause a depression of hematopoiesis. It is potentiated by sulfonamides and the trimethoprim-sulfamethoxazole combination is the form most often used. It is sometimes used alone as an antimalarial. Trimethoprim resistance has been reported. [PubChem] Trimethoprim. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=738-70-5 (retrieved 2024-07-09) (CAS RN: 738-70-5). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

   

Anisomycin

Flagecidin;Wuningmeisu C

C14H19NO4 (265.1314014)


An antibiotic isolated from various Streptomyces species. It interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system. D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents D004791 - Enzyme Inhibitors > D019384 - Nucleic Acid Synthesis Inhibitors D004791 - Enzyme Inhibitors > D011500 - Protein Synthesis Inhibitors D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents C254 - Anti-Infective Agent > C258 - Antibiotic relative retention time with respect to 9-anthracene Carboxylic Acid is 0.392 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.387 Anisomycin is a potent protein synthesis inhibitor which interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system[1]. Anisomycin is a JNK activator, which increases phospho-JNK[2][3]. Anisomycin is a bacterial antibiotic[4].

   
   

Lythramine

Lythramine

C29H37NO5 (479.26715920000004)


A piperidine alkaloid that is lythranidine with the hydroxy group C-10 esterified into an acetate and a methylene bridge formed between the hydroxy at C-9 and the piperidine nitrogen.

   

1,3,5-Trichloro-2-methoxybenzene

Benzene, 1,3,5-trichloro-2-methoxy- (9ci)

C7H5Cl3O (209.94059700000003)


1,3,5-Trichloro-2-methoxybenzene is found in alcoholic beverages. Off-odour component found in foods etc. Responsible for cork taint in wine

   

1-Methoxy-4-methylbenzene

InChI=1/C8H10O/c1-7-3-5-8(9-2)6-4-7/h3-6H,1-2H

C8H10O (122.07316100000001)


1-Methoxy-4-methylbenzene, also known as 4-methoxy-toluene or 4-methyl anisole, belongs to the class of organic compounds known as anisoles. These are organic compounds containing a methoxybenzene or a derivative thereof. 1-Methoxy-4-methylbenzene is a camphoraceous, cedar, and cresol tasting compound. 1-methoxy-4-methylbenzene has been detected, but not quantified, in a few different foods, such as garden tomato, herbs and spices, and milk and milk products. Isolated from ylang-ylang, cananga and other essential oilsand is also present in tomato and Camembert cheese. Flavouring ingredient. 1-Methoxy-4-methylbenzene is found in milk and milk products, herbs and spices, and garden tomato. 1-Methoxy-4-methylbenzene is a member of methoxybenzenes. 1-Methoxy-4-methylbenzene is a natural product found in Cananga odorata, Mimusops elengi, and other organisms with data available.

   

1,3,5-Trimethoxybenzene

1,3,5-Trimethoxybenzene, Standard for quantitative NMR, TraceCERT(R)

C9H12O3 (168.0786402)


1,3,5-Trimethoxybenzene has been found to be a potential biomarker of flavonoid intake in human. Flavonoids are phytochemicals that are widespread in the human diet. Despite limitations in their bioavailability, experimental and epidemiological data suggest health benefits of flavonoid consumption. Valid biomarkers of flavonoid intake may be useful for estimating exposure in a range of settings. However, to date, few useful flavonoid biomarkers have been identified. A recent urine analysis suggested that urinary 4-ethylphenol, benzoic acid, and 4-ethylbenzoic acid may be potential biomarkers of quercetin intake and 1,3,5-trimethoxybenzene, 4-O-methylgallic acid, 3-O-methylgallic acid, and gallic acid may be potential markers of epigallocatechin gallate intake. Potential biomarkers of (-)-epicatechin were not identified. These urinary biomarkers may provide an accurate indication of flavonoid exposure (PMID: 19812218). 1,3,5-trimethoxybenzene is a methoxybenzene carrying methoxy groups at positions 1, 3 and 5. It has been found to be a biomarker of flavonoid consumption in humans. It has a role as a biomarker and a human xenobiotic metabolite. 1,3,5-Trimethoxybenzene is a natural product found in Zieria chevalieri, Virola surinamensis, and other organisms with data available. A polyphenol metabolite detected in biological fluids [PhenolExplorer]. 1,3,5-Trimethoxybenzene is found in many foods, some of which are carob, coriander, plains prickly pear, and italian sweet red pepper. A methoxybenzene carrying methoxy groups at positions 1, 3 and 5. It has been found to be a biomarker of flavonoid consumption in humans. D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D010276 - Parasympatholytics 1,3,5-Trimethoxybenzene is a key component of the Chinese rose odor. 1,3,5-Trimethoxybenzene is synthesized in three successive methylation steps from phloroglucinol, the initial precursor[1].

   

Methocarbamol

2-Hydroxy-3-(2-methoxyphenoxy)propyl carbamic acid

C11H15NO5 (241.09501799999998)


Methocarbamol is only found in individuals that have used or taken this drug. It is a centrally acting muscle relaxant whose mode of action has not been established. It is used as an adjunct in the symptomatic treatment of musculoskeletal conditions associated with painful muscle spasm. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1206)The mechanism of action of methocarbamol in humans has not been established, but may be due to central nervous system depression. It has no direct action on the contractile mechanism of striated muscle, the motor end plate or the nerve fiber. M - Musculo-skeletal system > M03 - Muscle relaxants > M03B - Muscle relaxants, centrally acting agents > M03BA - Carbamic acid esters D018373 - Peripheral Nervous System Agents > D009465 - Neuromuscular Agents C78281 - Agent Affecting Musculoskeletal System > C29696 - Muscle Relaxant D002491 - Central Nervous System Agents

   

1-(4-Methoxyphenyl)-1-penten-3-one

(1E)-1-(4-methoxyphenyl)pent-1-en-3-one

C12H14O2 (190.09937440000002)


1-(4-Methoxyphenyl)-1-penten-3-one is a flavouring ingredien Flavouring ingredient

   

1,3,5-Trimethoxybenzene

1,3,5-Trimethoxybenzene

C9H12O3 (168.0786402)


D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D010276 - Parasympatholytics 1,3,5-Trimethoxybenzene is a key component of the Chinese rose odor. 1,3,5-Trimethoxybenzene is synthesized in three successive methylation steps from phloroglucinol, the initial precursor[1].

   

troxipide

troxipide

C15H22N2O4 (294.1579492)


A - Alimentary tract and metabolism > A02 - Drugs for acid related disorders > A02B - Drugs for peptic ulcer and gastro-oesophageal reflux disease (gord) C78276 - Agent Affecting Digestive System or Metabolism > C29701 - Anti-ulcer Agent

   

Trimethioprim

2,4-Diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine

C14H18N4O3 (290.1378838)


Trimethoprim. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=738-70-5 (retrieved 2024-07-09) (CAS RN: 738-70-5). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

   

methocarbamol

Methocarbamol (Robaxin)

C11H15NO5 (241.09501799999998)


M - Musculo-skeletal system > M03 - Muscle relaxants > M03B - Muscle relaxants, centrally acting agents > M03BA - Carbamic acid esters D018373 - Peripheral Nervous System Agents > D009465 - Neuromuscular Agents C78281 - Agent Affecting Musculoskeletal System > C29696 - Muscle Relaxant D002491 - Central Nervous System Agents CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 3

   
   

Trimethoxybenzene

Trimethoxybenzene

C9H12O3 (168.0786402)