Phaseollidin (BioDeep_00000005750)

Secondary id: BioDeep_00000640974, BioDeep_00000859673

human metabolite PANOMIX_OTCML-2023

代谢物信息卡片

15-(3-methylbut-2-en-1-yl)-8,17-dioxatetracyclo[8.7.0.0²,⁷.0¹¹,¹⁶]heptadeca-2(7),3,5,11(16),12,14-hexaene-5,14-diol

化学式: C20H20O4 (324.13615200000004)
中文名称: 菜豆素
谱图信息: 最多检出来源 Viridiplantae(plant) 0.24%

Reviewed

Last reviewed on 2024-08-20.

Cite this Page

Phaseollidin. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/phaseollidin (retrieved 2024-11-08) (BioDeep RN: BioDeep_00000005750). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: CC(=CCC1=C(C=CC2=C1OC3C2COC4=C3C=CC(=C4)O)O)C
InChI: InChI=1S/C20H20O4/c1-11(2)3-5-14-17(22)8-7-13-16-10-23-18-9-12(21)4-6-15(18)20(16)24-19(13)14/h3-4,6-9,16,20-22H,5,10H2,1-2H3

描述信息

Phaseollidin is found in common bean. Phaseollidin is isolated from kidney bean Phaseolus vulgaris, mung bean Phaseolus aureus, rice bean Phaseolus calcaratus, papadi Dolichos biflorus, and hyacinth bean Lablab niger.

同义名列表

5 个代谢物同义名

15-(3-methylbut-2-en-1-yl)-8,17-dioxatetracyclo[8.7.0.0²,⁷.0¹¹,¹⁶]heptadeca-2(7),3,5,11(16),12,14-hexaene-5,14-diol; (6aR,11aR)-6a,11a-Dihydro-10-(3-methyl-2-buten-1-yl)-6H-benzofuro[3,2-c][1]benzopyran-3,9-diol; Phaseolidin; 6a,11a-Dihydro-10-(3-methyl-2-butenyl)-6H-benzofuro[3,2-c][1]benzopyran-3,9-diol, 9ci; (-)-Phaseollidin; phaseollidin

数据库引用编号

16 个数据库交叉引用编号

ChEBI: CHEBI:17556
KEGG: C05230
PubChem: 119268
HMDB: HMDB0033669
Metlin: METLIN48100
ChEMBL: CHEMBL508534
MetaCyc: CPD-4885
KNApSAcK: C00002558
foodb: FDB011772
chemspider: 4292653
CAS: 37831-70-2
PMhub: MS000018614
LipidMAPS: LMPK12070011
3DMET: B01829
NIKKAJI: J18.400D
RefMet: Phaseollidin

分类词条

代谢反应

11 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(3)

pterocarpan phytoalexins modification (maackiain, medicarpin, pisatin, phaseollin): (-)-maackiain + H⁺ + NAD(P)H + O₂ ⟶ 1α-hydroxy-maackiain + H₂O + NAD(P)⁺
phaseollin biosynthesis: (-)-phaseollidin + H⁺ + NADPH + O₂ ⟶ (-)-phaseollin + H₂O + NADP⁺
superpathway of pterocarpan biosynthesis (via daidzein): (-)-glycinol + DMAPP ⟶ (6αS,11αS)-2-dimethylallyl-3,6α,9-trihydroxypterocarpan + diphosphate

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(8)

superpathway of pterocarpan biosynthesis (via daidzein): 2,4',7-trihydroxyisoflavanone ⟶ H₂O + daidzein
phaseollin biosynthesis: (6aR,11aR)-3,9-dihydroxypterocarpan + DMAPP ⟶ (-)-phaseollidin + diphosphate
superpathway of pterocarpan biosynthesis (via daidzein): (6αS,11αS)-2-dimethylallyl-3,6α,9-trihydroxypterocarpan + O₂ + a reduced [NADPH-hemoprotein reductase] ⟶ H₂O + an oxidized [NADPH-hemoprotein reductase] + glyceollin II
phaseollin biosynthesis: (-)-phaseollidin + H⁺ + NADPH + O₂ ⟶ (-)-phaseollin + H₂O + NADP⁺
phaseollin biosynthesis: (6aR,11aR)-3,9-dihydroxypterocarpan + DMAPP ⟶ (-)-phaseollidin + diphosphate
superpathway of pterocarpan biosynthesis (via daidzein): 2,4',7-trihydroxyisoflavanone ⟶ H₂O + daidzein
phaseollin biosynthesis: (6aR,11aR)-3,9-dihydroxypterocarpan + DMAPP ⟶ (-)-phaseollidin + diphosphate
phaseollin biosynthesis: (6aR,11aR)-3,9-dihydroxypterocarpan + DMAPP ⟶ (-)-phaseollidin + diphosphate

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

29 个相关的物种来源信息

1237573 - Erythrina abyssinica:
2590686 - Erythrina burana: 10.1021/NP50100A028
2590687 - Erythrina burttii:
2590687 - Erythrina burttii: 10.1016/S0031-9422(01)00459-9
49817 - Erythrina crista-galli:
49817 - Erythrina crista-galli: 10.1016/S0031-9422(97)00071-X
556509 - Erythrina fusca: 10.1248/CPB.57.993
3844 - Erythrina latissima:
647292 - Erythrina poeppigiana:
647292 - Erythrina poeppigiana: 10.1016/S0031-9422(02)00164-4
1977555 - Erythrina sigmoidea:
1977555 - Erythrina sigmoidea: 10.1016/S0031-9422(00)90489-8
3845 - Erythrina variegata:
1076878 - Erythrina velutina: 10.1016/S0305-1978(00)00077-6
347911 - Erythrina zeyheri:
347911 - Erythrina zeyheri: 10.1016/S0031-9422(03)00390-X
9606 - Homo sapiens: -
701533 - Lespedeza cyrtobotrya: 10.1021/NP800535G
3886 - Phaseolus coccineus: 10.1016/S0031-9422(00)80697-4
3885 - Phaseolus vulgaris: 10.1016/0031-9422(80)85139-9
3891 - Psophocarpus tetragonolobus: 10.1016/S0031-9422(00)89711-3
1323965 - Sophora moorcroftiana: 10.1248/CPB.39.1568
3918 - Vigna aconitifolia: 10.1016/0305-1978(92)90087-T
3914 - Vigna angularis: 10.1016/0305-1978(92)90087-T
3915 - Vigna mungo: 10.1016/0305-1978(92)90087-T
157791 - Vigna radiata:
115715 - Vigna subterranea: 10.1016/0305-1978(92)90087-T
87088 - Vigna umbellata: 10.1016/0305-1978(92)90087-T
3917 - Vigna unguiculata: 10.1016/0305-1978(92)90087-T

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Sarah M Nassief, Masouda E Amer, Eman Shawky, Kamakshi Sishtla, Eduard Mas-Claret, Anbukkarasi Muniyandi, Timothy W Corson, Dulcie A Mulholland, Sawsan El-Masry. Antiangiogenic Pterocarpan and Flavonoid Constituents of Erythrina lysistemon. Journal of natural products. 2023 04; 86(4):759-766. doi: 10.1021/acs.jnatprod.2c00909. [PMID: 36938984]
Hoda A S El-Garhy, Ahmed A Elsisi, Shereen A Mohamed, Osama M Morsy, Gamal Osman, Fayz A Abdel-Rahman. Transcriptomic changes in green bean pods against grey mould and white rot diseases via field application of chemical elicitor nanoparticles. IET nanobiotechnology. 2020 Sep; 14(7):574-583. doi: 10.1049/iet-nbt.2020.0004. [PMID: 33010132]
Chelliah Selvam, Brian C Jordan, Sandhya Prakash, Daniel Mutisya, Ramasamy Thilagavathi. Pterocarpan scaffold: A natural lead molecule with diverse pharmacological properties. European journal of medicinal chemistry. 2017 Mar; 128(?):219-236. doi: 10.1016/j.ejmech.2017.01.023. [PMID: 28189086]
Mehrdad Iranshahi, Hoan Vu, Ngoc Pham, Dusan Zencak, Paul Forster, Ronald J Quinn. Cytotoxic evaluation of alkaloids and isoflavonoids from the Australian tree Erythrina vespertilio. Planta medica. 2012 May; 78(7):730-6. doi: 10.1055/s-0031-1298310. [PMID: 22354391]
Wera Hauschild, Patrick B Chalo Mutiso, Claus M Passreiter. Prenylated pterocarpanes from Erythrina melanacantha. Natural product communications. 2010 May; 5(5):721-4. doi: . [PMID: 20521535]
Phi Hung Nguyen, Thi Van Thu Le, Phuong Thien Thuong, Trong Tuan Dao, Derek Tantoh Ndinteh, Joseph Tanyi Mbafor, Keon Wook Kang, Won Keun Oh. Cytotoxic and PTP1B inhibitory activities from Erythrina abyssinica. Bioorganic & medicinal chemistry letters. 2009 Dec; 19(23):6745-9. doi: 10.1016/j.bmcl.2009.09.108. [PMID: 19836230]
Phongsak Innok, Thitima Rukachaisirikul, Apichart Suksamrarn. Flavanoids and pterocarpans from the bark of Erythrina fusca. Chemical & pharmaceutical bulletin. 2009 Sep; 57(9):993-6. doi: 10.1248/cpb.57.993. [PMID: 19721263]
Maya Mori-Hongo, Hiromi Yamaguchi, Tsutomu Warashina, Toshio Miyase. Melanin synthesis inhibitors from Lespedeza cyrtobotrya. Journal of natural products. 2009 Jan; 72(1):63-71. doi: 10.1021/np800535g. [PMID: 19102656]
Abiy Yenesew, Jacob O Midiwo, Salome M Guchu, Matthias Heydenreich, Martin G Peter. Three isoflav-3-enes and a 2-arylbenzofuran from the root bark of Erythrina burttii. Phytochemistry. 2002 Feb; 59(3):337-41. doi: 10.1016/s0031-9422(01)00459-9. [PMID: 11830143]
M Taniguchi, I Kubo. Ethnobotanical drug discovery based on medicine men's trials in the African savanna: screening of east African plants for antimicrobial activity II. Journal of natural products. 1993 Sep; 56(9):1539-46. doi: 10.1021/np50099a012. [PMID: 8254349]
A C Buck. Disorders of micturition in bacterial prostatitis. Proceedings of the Royal Society of Medicine. 1975 Aug; 68(8):508-11. doi: NULL. [PMID: 681]