(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylic acid (BioDeep_00001869592)

Main id: BioDeep_00000005584

 


代谢物信息卡片


(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylic acid

化学式: C7H10O7 (206.042651)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(C(CC(=O)O)C(=O)O)(C(=O)O)O
InChI: InChI=1S/C7H10O7/c1-7(14,6(12)13)3(5(10)11)2-4(8)9/h3,14H,2H2,1H3,(H,8,9)(H,10,11)(H,12,13)/t3-,7-/m1/s1

描述信息

A 3-hydroxybutane-1,2,3-tricarboxylic acid which has (2S,3R) configuration.

同义名列表

1 个代谢物同义名

(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylic acid



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Toshiaki Komatsu, Hinako Morita, Yoko Takayama, Yui Natsume, Yoshinori Tomoda, Hirohisa Miura, Takeo Sato, Takatoshi Nakamura, Masaya Toda, Hirotsugu Okamoto, Hideaki Hanaki, Koichiro Atsuda. Timing of re-dosing based on population pharmacokinetic-pharmacodynamics target attainment analysis of cefmetazole in subjects undergoing lower gastrointestinal surgery. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy. 2022 Aug; 28(8):1105-1111. doi: 10.1016/j.jiac.2022.03.024. [PMID: 35400549]
  • Yoko Takayama, Toshiaki Komatsu, Takatoshi Nakamura, Yoshinori Tomoda, Masaya Toda, Hirohisa Miura, Takeo Sato, Koichiro Atsuda, Hirotsugu Okamoto, Hideaki Hanaki. Association of serum and fat tissue antibiotic concentrations with surgical site infections in lower gastrointestinal surgery. Surgery. 2022 04; 171(4):1000-1005. doi: 10.1016/j.surg.2021.10.013. [PMID: 34772516]
  • Toshiki Etani, Minami Asaoka, Shuhei Kondo, Chiharu Wachino, Kaoru Hori, Nobuhiko Shimizu, Yusuke Noda, Takashi Nagai, Satoshi Nozaki, Keitaro Iida, Taku Naiki, Ryosuke Ando, Noriyasu Kawai, Takeshi Yanagita, Atsushi Nakamura, Takahiro Yasui. Efficacy of fosfomycin in the prevention of postoperative infection following transurethral resection of bladder tumor during periods of limited cefazolin, cefotiam, and cefmetazole supply. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy. 2021 Apr; 27(4):625-631. doi: 10.1016/j.jiac.2020.11.025. [PMID: 33309628]
  • Akiyoshi Horie, Akiyoshi Nariai, Fumihide Katou, Yasuhiro Abe, Yuya Saito, Daisuke Koike, Tomohiro Hirade, Tomoko Ito, Miho Wakuri, Aiko Fukuma. Increased community-acquired upper urinary tract infections caused by extended-spectrum beta-lactamase-producing Escherichia coli in children and the efficacy of flomoxef and cefmetazole. Clinical and experimental nephrology. 2019 Nov; 23(11):1306-1314. doi: 10.1007/s10157-019-01775-w. [PMID: 31428892]
  • Natsuki Shioji, Minoru Mizutani, Mariko Okayama, Haruna Katayama, Eiko Ooya, Takao Sekine, Masahiro Masuya. [Drug-induced immune hemolytic anemia caused by cefmetazole]. [Rinsho ketsueki] The Japanese journal of clinical hematology. 2018 ; 59(7):884-888. doi: 10.11406/rinketsu.59.884. [PMID: 30078798]
  • Toshitaka Sugawara, Junichi Shindoh, Yujiro Nishioka, Masaji Hashimoto. Total bilirubin amount in drainage fluid can be an early predictor for severe biliary fistula after hepatobiliary surgery. Bioscience trends. 2017 Nov; 11(5):588-594. doi: 10.5582/bst.2017.01208. [PMID: 29070759]
  • Yinghui Fang, Yulong Guan, Caihong Wan, Zhida Fu, Juanjuan Jiang, Chunfu Wu, Ju Zhao, Peng Sun, Cun Long. The dynamic observation of plasma concentration of antimicrobial agents during balanced ultrafiltration in vitro. Artificial organs. 2014 Jan; 38(1):48-55. doi: 10.1111/aor.12113. [PMID: 23865445]
  • Takatoshi Nakamura, Atsushi Tomizawa, Hiroshi Inano, Takeo Sato, Kazuo Yago, Masahiko Watanabe. Tissue concentrations of antibiotics given prophylactically during colorectal cancer surgery. Hepato-gastroenterology. 2013 Sep; 60(126):1371-5. doi: 10.5754/hge13070. [PMID: 23933929]
  • Asako Doi, Toshihiko Shimada, Sohei Harada, Kentaro Iwata, Toru Kamiya. The efficacy of cefmetazole against pyelonephritis caused by extended-spectrum beta-lactamase-producing Enterobacteriaceae. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. 2013 Mar; 17(3):e159-63. doi: 10.1016/j.ijid.2012.09.010. [PMID: 23140947]
  • Tetsuhiro Owaki, Hiroshi Okumura, Yasuto Uchikado, Ken Sasaki, Masataka Matsumoto, Itaru Omoto, Tetsuro Setoyama, Yoshiaki Kita, Toshihide Sakurai, Daisuke Matsushita, Sumiya Ishigami, Shinichi Ueno, Shoji Natsugoe. Serum concentrations of antibiotics during severe invasive surgery such as esophagectomy for esophageal cancer. International surgery. 2013 Jan; 98(1):1-5. doi: 10.9738/cc164.1. [PMID: 23438269]
  • Y S Lin, R Radzi, M Morimoto, H Saimoto, Y Okamoto, S Minami. Characterization of chitosan-carboxymethyl dextran nanoparticles as a drug carrier and as a stimulator of mouse splenocytes. Journal of biomaterials science. Polymer edition. 2012; 23(11):1401-20. doi: 10.1163/092050611x582849. [PMID: 21740648]
  • Chang-I Ho, Yao-Ko Wen, Mei-Ling Chen. Xanthogranulomatous pyelonephritis successfully treated with antibiotics only. Journal of the Chinese Medical Association : JCMA. 2008 Dec; 71(12):643-5. doi: 10.1016/s1726-4901(09)70008-5. [PMID: 19114330]
  • Miki Katoh, Chise Tateno, Katsutoshi Yoshizato, Tsuyoshi Yokoi. Chimeric mice with humanized liver. Toxicology. 2008 Apr; 246(1):9-17. doi: 10.1016/j.tox.2007.11.012. [PMID: 18248870]
  • Hirotoshi Okumura, Miki Katoh, Keiichi Minami, Miki Nakajima, Tsuyoshi Yokoi. Change of drug excretory pathway by CCl4-induced liver dysfunction in rat. Biochemical pharmacology. 2007 Aug; 74(3):488-95. doi: 10.1016/j.bcp.2007.04.025. [PMID: 17544377]
  • Hirotoshi Okumura, Miki Katoh, Toshiro Sawada, Miki Nakajima, Yoshinori Soeno, Hikaru Yabuuchi, Toshihiko Ikeda, Chise Tateno, Katsutoshi Yoshizato, Tsuyoshi Yokoi. Humanization of excretory pathway in chimeric mice with humanized liver. Toxicological sciences : an official journal of the Society of Toxicology. 2007 Jun; 97(2):533-8. doi: 10.1093/toxsci/kfm041. [PMID: 17341479]
  • Masato Tomita, Satoru Motokawa. Effects of air tourniquet on the antibiotics concentration, in bone marrow, injected just before the start of operation. Modern rheumatology. 2007; 17(5):409-12. doi: 10.1007/s10165-007-0609-4. [PMID: 17929134]
  • Shin-ichi Otani, S Endo, Y Sato, T Hasegawa, N Saito, Y Sohara. [Feasibility of short-term antibiotic prophylaxis after pulmonary resection]. Kyobu geka. The Japanese journal of thoracic surgery. 2004 Dec; 57(13):1171-4; discussion 1175. doi: NULL. [PMID: 15609652]
  • M Takeuchi, M Harada, M Nagata, A Watanabe, K Nakamura. [Immunological properties of S-1090, cefmatilen hydrochloride hydrate]. The Journal of toxicological sciences. 2001 May; 26 Suppl 1(?):231-42. doi: NULL. [PMID: 11400315]
  • K Goto, M Oda, H Saitoh, M Nishida, M Takada. Effect of side chains including the N-methyl-tetrazole-thiol group of beta-lactam antibiotics on transport in cultured kidney epithelial cells LLC-PK1. Biological & pharmaceutical bulletin. 1998 Oct; 21(10):1113-6. doi: 10.1248/bpb.21.1113. [PMID: 9821822]
  • G A Breen, W L St Peter. Hypoprothrombinemia associated with cefmetazole. The Annals of pharmacotherapy. 1997 Feb; 31(2):180-4. doi: 10.1177/106002809703100210. [PMID: 9034420]
  • C Si, G Tian. [The evaluation of cefmetazole in clinical use. The study group of cefmetazole in clinical use]. Zhonghua nei ke za zhi. 1996 Oct; 35(10):668-72. doi: NULL. [PMID: 9592326]
  • M T Fields, B L Herndon, D M Bamberger. beta-Lactamase-mediated inactivation and efficacy of cefazolin and cefmetazole in Staphylococcus aureus abscesses. Antimicrobial agents and chemotherapy. 1993 Feb; 37(2):203-6. doi: 10.1128/aac.37.2.203. [PMID: 8452349]
  • M J García-Agundez, C Fernández-Lastra, R Jiménez, J González, E L Mariño. Pharmacokinetic parameters from data relating to the plasma and biliary excretion kinetics of cefmetazole in rats. European journal of drug metabolism and pharmacokinetics. 1992 Jul; 17(3):167-73. doi: 10.1007/bf03190141. [PMID: 1490484]
  • T Hirano, T Manabe, G Ohshio, Y Nio. Improved survival in mice with diet-induced pancreatitis treated with new potent protease inhibitor, E-3123 and a broad spectrum antibiotic, cefmetazole. Nihon geka hokan. Archiv fur japanische Chirurgie. 1992 May; 61(3):213-23. doi: NULL. [PMID: 1444701]
  • J E Schweinle, M Nishiyasu. Sub-minimal inhibitory concentrations of cefmetazole enhance serum bactericidal activity in vitro by amplifying poly-C9 deposition. The Journal of clinical investigation. 1992 Apr; 89(4):1198-207. doi: 10.1172/jci115703. [PMID: 1556181]
  • F Cava, J Gonzalez, J M Gonzalez-Buitrago, C Muriel, R Jimenez. Inhibition of biliary cholesterol and phospholipid secretion by cefmetazole. The role of vesicular transport and of canalicular events. The Biochemical journal. 1991 May; 275 ( Pt 3)(?):591-5. doi: 10.1042/bj2750591. [PMID: 1674860]
  • A B Rodriguez, C Barriga, M de la Fuente. Stimulation of phagocytic processes and antibody-dependent cellular cytotoxicity of human neutrophils by cefmetazole. Microbiology and immunology. 1991; 35(7):545-56. doi: 10.1111/j.1348-0421.1991.tb01585.x. [PMID: 1784256]
  • H Yanagi, N Ishikura, H Kenmotsu, N Yagi, K Goto, S Kato, S Sumiya, M Takada. [Effect of inclusion complexation of decanoic acid with alpha-cyclodextrin on rectal absorption of cefmetazole sodium suppository in rabbits]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 1991 Jan; 111(1):65-9. doi: 10.1248/yakushi1947.111.1_65. [PMID: 2056446]
  • L S Welage, M T Borin, J H Wilton, L G Hejmanowski, P B Wels, J J Schentag. Comparative evaluation of the pharmacokinetics of N-methylthiotetrazole following administration of cefoperazone, cefotetan, and cefmetazole. Antimicrobial agents and chemotherapy. 1990 Dec; 34(12):2369-74. doi: 10.1128/aac.34.12.2369. [PMID: 2088192]
  • N Wada, K Fukunaga, M Kubo. [Two cases of Yersinia pseudotuberculosis infection in children]. Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases. 1990 Nov; 64(11):1462-7. doi: 10.11150/kansenshogakuzasshi1970.64.1462. [PMID: 2286788]
  • M T Borin, G R Peters, T C Smith. Pharmacokinetics and dose proportionality of cefmetazole in healthy young and elderly volunteers. Antimicrobial agents and chemotherapy. 1990 Oct; 34(10):1944-8. doi: 10.1128/aac.34.10.1944. [PMID: 2291659]
  • J Igari, M Shitara, M Shitara, K Yoshimoto, Y Hayashi. [Susceptibilities of uropathogenic bacteria to ampicillin, cefazolin, cefmetazole and gentamicin. Nine-year survey of changing patterns of susceptibilities]. The Japanese journal of antibiotics. 1990 Sep; 43(9):1530-7. doi: . [PMID: 2262960]
  • J Igari, M Shitara, M Shitara, K Yoshimoto, Y Hayashi. [In vitro susceptibility of Escherichia coli and Klebsiella sp. to antibiotics]. The Japanese journal of antibiotics. 1990 Apr; 43(4):659-69. doi: NULL. [PMID: 2199690]
  • C E Halstenson, D R Guay, J A Opsahl, C A Hirata, L S Olanoff, E Novak, H Ko, K S Cathcart, G R Matzke. Disposition of cefmetazole in healthy volunteers and patients with impaired renal function. Antimicrobial agents and chemotherapy. 1990 Apr; 34(4):519-23. doi: 10.1128/aac.34.4.519. [PMID: 2344159]
  • J Morisaki, N Morisaki, T Chimura. [A study of tissue transfer of cefmetazole in the blood and uterus in pregnant rabbits]. The Japanese journal of antibiotics. 1990 Feb; 43(2):318-20. doi: NULL. [PMID: 2362353]
  • R N Jones. Cefmetazole (CS-1170), a "new" cephamycin with a decade of clinical experience. Diagnostic microbiology and infectious disease. 1989 Sep; 12(5):367-79. doi: 10.1016/0732-8893(89)90106-5. [PMID: 2692950]
  • J S Tan, S J Salstrom, S A Signs, H E Hoffman, T M File. Pharmacokinetics of intravenous cefmetazole with emphasis on comparison between predicted theoretical levels in tissue and actual skin window fluid levels. Antimicrobial agents and chemotherapy. 1989 Jun; 33(6):924-7. doi: 10.1128/aac.33.6.924. [PMID: 2764542]
  • H Takeuchi, Y Okada, O Yoshida, T Konishi, T Tomoyoshi, S Nakahara. [Urinary tract infection associated with urinary calculi. 2. Effects of antibiotics on bacteria within infected stones]. Hinyokika kiyo. Acta urologica Japonica. 1989 May; 35(5):755-61. doi: NULL. [PMID: 2801373]
  • M Sugimoto, K Saito, M Hashimoto, S Horie, Y Wakabayashi, S Hirose, Y Murata, M Kobayashi. [Antibiotics-induced agranulocytosis. Patient's IgG inhibits a GM colony formation]. [Rinsho ketsueki] The Japanese journal of clinical hematology. 1989 May; 30(5):768-73. doi: NULL. [PMID: 2795889]
  • J B Moe, R C Piper, H Tanase, K Sotani, J Manabe. Preclinical safety studies of cefmetazole. The Journal of antimicrobial chemotherapy. 1989 Apr; 23 Suppl D(?):125-9. doi: 10.1093/jac/23.suppl_d.125. [PMID: 2722719]
  • H Ko, E Novak, G R Peters, W M Bothwell, J D Hosley, S K Closson, W J Adams. Pharmacokinetics of single-dose cefmetazole following intramuscular administration of cefmetazole sodium to healthy male volunteers. Antimicrobial agents and chemotherapy. 1989 Apr; 33(4):508-12. doi: 10.1128/aac.33.4.508. [PMID: 2729944]
  • J T DiPiro, J E Connors, T A Bowden, J A Stanfield, B M Lampert, J T Stewart. Comparative intraoperative concentrations of two cephalosporins with activity against anaerobic bacteria. The Journal of antimicrobial chemotherapy. 1989 Apr; 23 Suppl D(?):89-95. doi: 10.1093/jac/23.suppl_d.89. [PMID: 2722728]
  • H Ko, K S Cathcart, D L Griffith, G R Peters, W J Adams. Pharmacokinetics of intravenously administered cefmetazole and cefoxitin and effects of probenecid on cefmetazole elimination. Antimicrobial agents and chemotherapy. 1989 Mar; 33(3):356-61. doi: 10.1128/aac.33.3.356. [PMID: 2729930]
  • W M Bothwell, K S Cathcart, P A Bombardt. An on-line, column-switching high-performance liquid chromatographic procedure for the removal of probenecid from human plasma, serum, or urine in the quantitative determination of cefmetazole or cefoxitin. Journal of pharmaceutical and biomedical analysis. 1989; 7(8):987-95. doi: 10.1016/0731-7085(89)80024-x. [PMID: 2490108]
  • M K Ito, M A Gill, F C Chenella, T V Berne, A E Yellin, P N Heseltine, M D Appleman. Intraoperative serum, bile, and gallbladder-wall concentrations of cefmetazole in patients undergoing cholecystectomy. Clinical pharmacy. 1988 Jun; 7(6):467-8. doi: NULL. [PMID: 3165314]
  • F Soriano, M Santamaría, C Ponte, C Castilla, R Fernández-Roblas. In vivo significance of the inoculum effect of antibiotics on Escherichia coli. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology. 1988 Jun; 7(3):410-2. doi: 10.1007/bf01962350. [PMID: 3137046]
  • T Hayashi, A Maruden, K Irimura, M Kuwata, K Morita. [Nephrotoxicity of cefodizime sodium in rats--single and 14-day repeated intravenous administration]. The Journal of toxicological sciences. 1988 Jun; 13 Suppl 1(?):285-327. doi: 10.2131/jts.13.supplementi_285. [PMID: 3172294]
  • K Yoshino, K Fujita, M Takemoto, M Suga. [Penetration of cefmetazole and netilmicin into the cerebrospinal fluid]. The Japanese journal of antibiotics. 1988 May; 41(5):563-6. doi: NULL. [PMID: 3216478]
  • J A Stanfield, J T DiPiro. Interference of cefmetazole sodium and cefotetan disodium with urine-glucose testing systems. American journal of hospital pharmacy. 1988 Mar; 45(3):625-6. doi: 10.1093/ajhp/45.3.625. [PMID: 3163470]
  • T Miura, I Hashimoto, Y Sawada, T Nakamura, M Nakahara. [Pharmacokinetics of cefmetazole during and after surgical operations]. The Japanese journal of antibiotics. 1987 Nov; 40(11):1923-36. doi: NULL. [PMID: 3481836]
  • S Asari, M Horikawa, H Tsukamoto, K Kouda, C Hayashi, K Miyai. [Susceptibility of clinical isolates to aztreonam]. The Japanese journal of antibiotics. 1987 Jul; 40(7):1317-31. doi: . [PMID: 3479624]
  • H Nakahata, Y Hirai, Y Kumasaka, T Miyazawa, T Nakamura, K Imamura, I Makino, K Takebe, H Kudo. [Free methyltetrazolethiol concentrations in men subjected to intravenous administration of cephems with methyltetrazolethiol]. The Japanese journal of antibiotics. 1987 Jul; 40(7):1294-8. doi: NULL. [PMID: 3479623]
  • M Shiga, M Hayashi, T Horie, S Awazu. Differences in the promotion mechanism of the colonic absorption of antipyrine, phenol red and cefmetazole. The Journal of pharmacy and pharmacology. 1987 Feb; 39(2):118-23. doi: 10.1111/j.2042-7158.1987.tb06956.x. [PMID: 2881996]
  • J Igari, M Shitara, M Morimoto, N Shiga, N Kosakai. [A nationwide study of the antimicrobial susceptibility of clinical isolates of Escherichia coli in Japan]. The Japanese journal of antibiotics. 1986 Nov; 39(11):3094-109. doi: NULL. [PMID: 3546776]
  • J Igari, M Shitara, M Morimoto, N Shiga, N Kosakai. [A nationwide study of the antimicrobial susceptibility of clinical isolates of Klebsiella sp. in Japan]. The Japanese journal of antibiotics. 1986 Nov; 39(11):3110-24. doi: NULL. [PMID: 3469423]
  • H Takahagi, K Inoue, M Horiguchi. Drug monitoring by a fully automated high-performance liquid chromatographic technique, involving direct injection of plasma. Journal of chromatography. 1986 Feb; 352(?):369-79. doi: 10.1016/s0021-9673(01)83394-x. [PMID: 3457796]
  • Y Kumasaka, H Nakahata, Y Hirai, K Imamura, K Takebe, I Suzuki, H Senda. [In vivo antibacterial activity of cefbuperazone. Synergy of cefbuperazone for bactericidal effect with human polymorphonuclear leukocytes]. The Japanese journal of antibiotics. 1986 Jan; 39(1):154-8. doi: NULL. [PMID: 3517405]
  • J Rodriguez-Barbero, E L Mariño, A Dominguez-Gil. Pharmacokinetics of cefmetazole administered intramuscularly and intravenously to healthy adults. Antimicrobial agents and chemotherapy. 1985 Oct; 28(4):544-7. doi: 10.1128/aac.28.4.544. [PMID: 3865631]
  • J Rodriquez Barbero, E L Mariño, A Dominquez-Gil, J Garcia Garcia, J M Rodriquez Rodriquez, A Gomez Alonso. Cefmetazole plasma levels after intraincisional administration. Drug intelligence & clinical pharmacy. 1985 May; 19(5):394-6. doi: 10.1177/106002808501900516. [PMID: 3859398]
  • M Sekine, H Terashima, K Sasahara, K Nishimura, R Okada, S Awazu. Improvement of bioavailability of poorly absorbed drugs. II. Effect of medium chain glyceride base on the intestinal absorption of cefmetazole sodium in rats and dogs. Journal of pharmacobio-dynamics. 1985 Apr; 8(4):286-95. doi: 10.1248/bpb1978.8.286. [PMID: 3861846]
  • T Ueda, K Sakai, M Fujimoto. Studies of cefotaxime serum concentrations during surgery under general anaesthesia and its passage to the wound fluid after surgery for breast cancer. Infection. 1985; 13 Suppl 1(?):S43-5. doi: 10.1007/bf01644217. [PMID: 3863795]
  • J Shimada, Y Hayashi, K Nakamura. Cefmetazole: clinical evaluation of efficacy and safety in Japan. Drugs under experimental and clinical research. 1985; 11(3):181-94. doi: . [PMID: 3869805]
  • J R Rodríguez, E L Mariño, M J Otero, J R Commes, J Garcia, J M Rodriguez, F Lozano, A Dominguez-Gil, A G Alonso. Concentrations of cefmetazole in plasma and tissue resulting from peri-incisional administration before appendectomy. Antimicrobial agents and chemotherapy. 1984 Nov; 26(5):787-8. doi: 10.1128/aac.26.5.787. [PMID: 6595964]
  • K Fujita, M Sugimoto, T Hara, T Murayama. [Concentration of antibiotics in the prostate: cefmetazole]. The Japanese journal of antibiotics. 1984 Sep; 37(9):1694-6. doi: NULL. [PMID: 6210377]
  • T Watanabe, T Hara, T Kasai, T Ishii, K Miyauchi, H Date, M Jinzaki, H Shindo, A Matsugami, H Goi. [Antibacterial activity of MT-141 against anaerobic bacteria]. The Japanese journal of antibiotics. 1984 Jun; 37(6):1058-69. doi: . [PMID: 6092738]
  • T Miyano, T Arai, H Shimomura, T Ogawa, K Sasaki, E Deguchi, K Suruga, H Nittono. [The correlation between the biliary excretion of cefmetazole and the bile acid metabolism in postoperative patients with biliary atresia]. The Japanese journal of antibiotics. 1984 Feb; 37(2):243-6. doi: NULL. [PMID: 6588213]
  • T Miyano, H Shimomura, T Arai, K Sasaki, T Ogawa, E Deguchi, K Suruga. [Postoperative evaluation of renal function from the aspect of urinary concentration of cefmetazole in infants and children with vesicoureteral reflux and hydronephrosis. I]. The Japanese journal of antibiotics. 1984 Feb; 37(2):237-42. doi: NULL. [PMID: 6588212]
  • H Mitsuya, Y Naide, K Ohtaguro, A Segawa. [Clinical evaluation of cefmetazole in urological infections]. Hinyokika kiyo. Acta urologica Japonica. 1984 Jan; 30(1):87-95. doi: . [PMID: 6587764]
  • T Nishihata, H Takahagi, M Yamamoto, H Tomida, J H Rytting, T Higuchi. Enhanced rectal absorption of cefmetazole and cefoxitin in the presence of epinephrine metabolites in rats and a high-performance liquid chromatographic assay for cephamycin antibiotics. Journal of pharmaceutical sciences. 1984 Jan; 73(1):109-12. doi: 10.1002/jps.2600730129. [PMID: 6582265]
  • H Takeuchi, T Tomoyoshi. [Treatment of infection stones. I. Dissolution of experimental infection stones in rats]. Hinyokika kiyo. Acta urologica Japonica. 1983 Mar; 29(3):293-6. doi: NULL. [PMID: 6375314]
  • T Miwatani, Y Takeda, K Kotera, T Nishimura, T Takashima, K Hiromatsu, K Tabuki, S Fujimoto, T Kamiki, E Yoshizaki, E Yabuuchi, Y Shimizu, K Matsunaga, K Yamanaka, I Furuta, M Iimori, J Kodama, M Tanaka, K Maejima, M Nukina, E Takashima, M Takahashi, O Harikane, T Masutani. [The antibacterial activity of new cephem antibiotics against clinical isolates. A comparison of the antibacterial activity of cefotaxime with 6 other antibiotics]. The Japanese journal of antibiotics. 1983 Feb; 36(2):260-76. doi: NULL. [PMID: 6304368]
  • T Nagao, M Komatsuda, K Yamauchi, H Nozaki. Clinical evaluation of combination of cefmetazole and piperacillin in the treatment of infections in patients with acute leukemia. Chemotherapy. 1983; 29(3):230-5. doi: 10.1159/000238202. [PMID: 6223792]
  • F Doko. [Preliminary and clinical investigations of cefmetazole in the obstetric and gynecological field]. The Japanese journal of antibiotics. 1982 Aug; 35(8):1951-6. doi: NULL. [PMID: 6961239]
  • M Suwaki, N Kashiwa, N Nohara. [Experimental studies of cefmetazole in the field of dermatology]. The Japanese journal of antibiotics. 1982 Aug; 35(8):1957-60. doi: NULL. [PMID: 6961240]
  • E Konaga, Y Orita, T Kawamura, T Mannami, K Orita, K Mano, K Kataoka, H Kimura, J Shimizu, T Kanbayashi, H Fujii, Y Okada, O Kondo, N Miyata, K Ohmori, N Chikazawa, K Kondo, H Sakai, S Kayata, K Nakajima, Y Ide, J Nakagawa, J Kotani, M Yumura, T Hatayama, N Kobayashi, T Souji, T Ohta, K Sakai, J Kasahara, Y Kuwata, E Kashihara, M Sakamoto, M Narusue, T Yagi, M Inoue. [Basic and clinical evaluations of cefmetazole in postoperative wound infections]. The Japanese journal of antibiotics. 1982 Jul; 35(7):1690-8. doi: . [PMID: 6757470]
  • H Shindo, K Kawai, T Ikeda, I Igarashi, S Sugawara. Absorption, distribution, excretion and metabolism of cefmetazole in cynomolgus monkeys. The Journal of antibiotics. 1982 Jun; 35(6):742-54. doi: 10.7164/antibiotics.35.742. [PMID: 6956564]
  • Y Minami, M Taguchi, R Nanba, H Tsuto, T Yamamoto, K Ueda, T Tsushima, T Morihana, K Nagata, K Nakao, K Shimada. [Experimental and clinical studies of cefmetazole in the field of oral surgery]. The Japanese journal of antibiotics. 1982 May; 35(5):1308-21. doi: NULL. [PMID: 6957626]
  • K Wada, S Baba, T Hatano, K Murai, H Kinoshita, I Takimoto, T Nomura, M Naito, S Iwata, T Nishimura, A Takasu, T Sekiya, K Miyagawa, M Tsukiyama, H Ito, Y Suzuki, J Hondoh, M Noda, K Umeda, T Maruo. [Pharmacokinetics and clinical studies of cefmetazole in the otorhinolaryngological field]. The Japanese journal of antibiotics. 1982 May; 35(5):1261-90. doi: NULL. [PMID: 6752461]
  • M Sekine, K Sasahara, T Kojima, T Morioka. High-performance liquid chromatographic method for determination of cefmetazole in human serum. Antimicrobial agents and chemotherapy. 1982 May; 21(5):740-3. doi: 10.1128/aac.21.5.740. [PMID: 6954877]
  • M Kawashima, H Tamura, Y Kitahara, K Jinyama. [Basic study on efficacy of cefmetazole against osseous and articular infections (author's transl)]. The Japanese journal of antibiotics. 1982 Mar; 35(3):835-9. doi: NULL. [PMID: 6954290]
  • T Motohiro, Y Sakata, T Fujimoto, T Nishiyama, K Ishimoto, K Tominaga, F Yamashita, Y Onoda, T Kusayanagi, M Tsuboi, Y Toubo, M Yamamoto, R Komatsu, C Tanaka, Y Baba. [Laboratory and clinical studies of cefmetazole in serious infection by Staphylococcus (author's transl)]. The Japanese journal of antibiotics. 1982 Mar; 35(3):821-34. doi: . [PMID: 6954289]
  • S Goto, H Sakamoto, M Ogawa, A Tsuji, S Kuwahara. Bactericidal activity of cefazolin, cefoxitin, and cefmetazole against Escherichia coli and Klebsiella pneumoniae. Chemotherapy. 1982; 28(1):18-25. doi: 10.1159/000238056. [PMID: 7035088]
  • T Nagao, M Komatsuda, K Yamauchi, H Nozaki, S Arimori. Evaluation of cefmetazole and piperacillin with or without tobramycin for infections in patients with hematological disorders. The Tokai journal of experimental and clinical medicine. 1981 Oct; 6(4):415-20. doi: . [PMID: 6459664]
  • N Iwai, A Sasaki, Y Taneda, K Inokuma. [A study on cefmetazole in the neonatal period (author's transl)]. The Japanese journal of antibiotics. 1981 Jun; 34(6):881-92. doi: NULL. [PMID: 6945448]
  • J Yura, N Tsuruga, S Hayashi. [Studies on absorption and excretion of cefmetazole in neonates and excretion into the bile of infants with congenital biliary atresia (author's transl)]. The Japanese journal of antibiotics. 1981 Jun; 34(6):903-6. doi: NULL. [PMID: 6945450]
  • NULL. [Cefmetazole preparations]. The Japanese journal of antibiotics. 1981 Jun; 34(6):925-8. doi: NULL. [PMID: 6945453]
  • N Cho, K Fukunaga, K Kunii. [A study of clinical application of cefmetazole in perinatal period (author's transl)]. The Japanese journal of antibiotics. 1981 Jun; 34(6):915-24. doi: . [PMID: 6945452]
  • S Nanri, K Sunakawa, N Yamashita, H Akita, M Hotta, Y Ichihashi, K Ishikawa, K Okazaki, T Kanemitsu, S Ri. [Examination of blood levels and urinary excretion of cefmetazole in the mature and immature neonates (author's transl)]. The Japanese journal of antibiotics. 1981 Jun; 34(6):874-9. doi: NULL. [PMID: 6945447]
  • M Ohkawa, M Orito, T Sugata, M Shimamura, M Sawaki, E Nakashita, K Kuroda, K Sasahara. Pharmacokinetics of cefmetazole in normal subjects and in patients with impaired renal function. Antimicrobial agents and chemotherapy. 1980 Sep; 18(3):386-9. doi: 10.1128/aac.18.3.386. [PMID: 6932824]
  • M Minamitani, H Hayashi, T Tohma, T Kojima, Y Sahashi, T Terao. [Studies on the shift of cefmetazole into the gastrointestinal tract (author's transl)]. The Japanese journal of antibiotics. 1980 Jan; 33(1):10-7. doi: NULL. [PMID: 6929355]