3-phosphoglycerate (BioDeep_00000014379)

 

Secondary id: BioDeep_00000001314, BioDeep_00000270834, BioDeep_00000405372

human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite BioNovoGene_Lab2019


代谢物信息卡片


3-(Dihydrogen phosphoric acid)glyceric acid

化学式: C3H7O7P (185.9929)
中文名称: 3-磷酸甘油酸, 磷酸甘油酸二钠盐
谱图信息: 最多检出来源 Homo sapiens(plant) 10.2%

Reviewed

Last reviewed on 2024-09-13.

Cite this Page

3-phosphoglycerate. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/3-phosphoglycerate (retrieved 2024-12-22) (BioDeep RN: BioDeep_00000014379). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C(C(C(=O)O)O)OP(=O)(O)O
InChI: InChI=1S/C3H7O7P/c4-2(3(5)6)1-10-11(7,8)9/h2,4H,1H2,(H,5,6)(H2,7,8,9)

描述信息

3-Phosphoglyceric acid, also known as 3PG, belongs to the class of organic compounds known as sugar acids and derivatives. Sugar acids and derivatives are compounds containing a saccharide unit which bears a carboxylic acid group. 3PG is the conjugate acid of glycerate 3-phosphate (GP or G3P). It is a solid that is soluble in water. 3-Phosphoglyceric acid exists in all living species, ranging from bacteria to humans. The glycerate is a biochemically significant metabolic intermediate in both glycolysis and the Calvin cycle. This is the first compound formed during the C3 or Calvin cycle. Glycerate 3-phosphate is also a precursor for serine, which, in turn, can create cysteine and glycine through the homocysteine cycle. Within humans, 3-phosphoglyceric acid participates in a number of enzymatic reactions. In particular, 3-phosphoglyceric acid can be biosynthesized from glyceric acid 1,3-biphosphate, which is mediated by the enzyme phosphoglycerate kinase 1. In addition, 3PG can be converted into 2-phospho-D-glyceric acid, which is catalyzed by the enzyme phosphoglycerate mutase 2. 3-phosphoglyceric acid is involved in the Warburg effect (aerobic glycolysis), a metabolic shift that is a hallmark of cancer (PMID: 29362480).
3-phosphoglyceric acid (3PG) is a 3-carbon molecule that is a metabolic intermediate in both glycolysis and the Calvin cycle. This chemical is often termed PGA when referring to the Calvin cycle. In the Calvin cycle, two glycerate 3-phosphate molecules are reduced to form two molecules of glyceraldehyde 3-phosphate (GALP). (wikipedia) [HMDB]
KEIO_ID P028

同义名列表

32 个代谢物同义名

3-(Dihydrogen phosphoric acid)glyceric acid; 2-hydroxy-3-(phosphonooxy)propanoic acid; 3-(Dihydrogen phosphate)glyceric acid; 3-Phosphoglycerate, monosodium salt; 3-Phosphoglycerate, trisodium salt; DL-Glyceric acid 3-phosphoric acid; 3-(Dihydrogen phosphate)glycerate; Glyceric acid 3-phosphoric acid; 3-Phosphoglycerate, (R)-isomer; D-(-)-3-Phosphoglyceric acid; Glyceric acid 3-phosphates; Glyceric acid 3-phosphate; DL-Glycerate 3-phosphate; 3-Glycerophosphoric acid; 3-Phospho-glyceric acid; 3-Phospho-(R)-glycerate; D-Glycerate 3-phosphate; 3-Phosphoglyceric acid; Glycerate 3-phosphates; 3-Phospho-D-glycerate; Glycerate 3-phosphate; 3-Glycerophosphorate; 3-Phospho-glycerate; 3-phosphoglycerate; Phosphoglycerate; 3-p-D-Glycerate; Glycerate-3-p; 3-p-Glycerate; 3-PGA; 3-PG; G3P; 3-Phosphoglycerate



数据库引用编号

17 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

144 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(6)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(138)

PharmGKB(0)

8 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

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  • Pauline Duminil, Marlène Davanture, Céline Oury, Edouard Boex-Fontvieille, Guillaume Tcherkez, Michel Zivy, Michael Hodges, Nathalie Glab. Arabidopsis thaliana 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 2 activity requires serine 82 phosphorylation. The Plant journal : for cell and molecular biology. 2021 09; 107(5):1478-1489. doi: 10.1111/tpj.15395. [PMID: 34174129]
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  • Yongchan Lee, Tomohiro Nishizawa, Mizuki Takemoto, Kaoru Kumazaki, Keitaro Yamashita, Kunio Hirata, Ayumi Minoda, Satoru Nagatoishi, Kouhei Tsumoto, Ryuichiro Ishitani, Osamu Nureki. Structure of the triose-phosphate/phosphate translocator reveals the basis of substrate specificity. Nature plants. 2017 Oct; 3(10):825-832. doi: 10.1038/s41477-017-0022-8. [PMID: 28970497]
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