Mutatochrome (BioDeep_00000006879)

 

Secondary id: BioDeep_00000393891, BioDeep_00000638846

human metabolite PANOMIX_OTCML-2023 Endogenous natural product PANOMIX_OTCML-2025


代谢物信息卡片


4,4,7a-trimethyl-2-[(2E,4E,6E,8E,10E,12E,14E,16E)-6,11,15-trimethyl-17-(2,6,6-trimethylcyclohex-1-en-1-yl)heptadeca-2,4,6,8,10,12,14,16-octaen-2-yl]-2,4,5,6,7,7a-hexahydro-1-benzofuran

  化学式: C40H56O (552.4331)
中文名称: 橘黃質
  谱图信息: 最多检出来源 Viridiplantae(otcml) 19.44%

Reviewed

Last reviewed on 2025-06-23.

Cite this Page

Mutatochrome. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/mutatochrome (retrieved 2025-08-02) (BioDeep RN: BioDeep_00000006879). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: CC(C=CC=C(C)C=CC1=C(C)CCCC1(C)C)=CC=CC=C(C)C=CC=C(C)C1C=C2C(C)(C)CCCC2(C)O1
InChI: InChI=1S/C40H56O/c1-30(19-13-20-32(3)24-25-35-33(4)23-15-26-38(35,6)7)17-11-12-18-31(2)21-14-22-34(5)36-29-37-39(8,9)27-16-28-40(37,10)41-36/h11-14,17-22,24-25,29,37H,15-16,23,26-28H2,1-10H3/b12-11+,19-13+,21-14+,25-24+,30-17+,31-18+,32-20+,34-22+/t37-,40+/m1/s1


描述信息

Mutatochrome, also known as citroxanthin, is a member of the class of compounds known as xanthophylls. Xanthophylls are carotenoids containing an oxygenated carotene backbone. Carotenes are characterized by the presence of two end-groups (mostly cyclohexene rings, but also cyclopentene rings or acyclic groups) linked by a long branched alkyl chain. Carotenes belonging form a subgroup of the carotenoids family. Xanthophylls arise by oxygenation of the carotene backbone. Thus, mutatochrome is considered to be an isoprenoid lipid molecule. Mutatochrome is practically insoluble (in water) and an extremely weak basic (essentially neutral) compound (based on its pKa). Mutatochrome can be found in a number of food items such as passion fruit, citrus, sweet orange, and pepper (c. frutescens), which makes mutatochrome a potential biomarker for the consumption of these food products. Mutatochrome (5,8-epoxy-β-carotene) is a carotenoid. It is the predominant carotenoid in the cap of the bolete mushroom Boletus luridus .
Mutatochrome is found in bitter gourd. Mutatochrome is a constituent of orange peel, Calendula officinalis (pot marigold) and Capsicum annuum (paprika) and others.
D020011 - Protective Agents > D000975 - Antioxidants > D002338 - Carotenoids

同义名列表

9 个代谢物同义名

4,4,7a-trimethyl-2-[(2E,4E,6E,8E,10E,12E,14E,16E)-6,11,15-trimethyl-17-(2,6,6-trimethylcyclohex-1-en-1-yl)heptadeca-2,4,6,8,10,12,14,16-octaen-2-yl]-2,4,5,6,7,7a-hexahydro-1-benzofuran; 5,8-Epoxy-5,8-dihydro-b,b-carotene; 5,8-Monoepoxy-beta-carotene; beta-carotene 5,8-epoxide; Citroxanthin; Mutatochrome; Mutachrome; Flavacin?; Citroxanthin



数据库引用编号

18 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome()

BioCyc()

PlantCyc()

代谢反应

个相关的代谢反应过程信息。

Reactome()

BioCyc()

WikiPathways()

Plant Reactome()

INOH()

PlantCyc()

COVID-19 Disease Map()

PathBank()

PharmGKB()

109 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Kia K Kemppainen, Esko Kemppainen, Howard T Jacobs. The alternative oxidase AOX does not rescue the phenotype of tko25t mutant flies. G3 (Bethesda, Md.). 2014 Aug; 4(10):2013-21. doi: 10.1534/g3.114.013946. [PMID: 25147191]
  • Sladana Zivković, Milos Kostov, Svetlana Pavlović, Zaklina Mijović. [Histopathological characteristics and coexpression of p53 and p16(INK4a) proteins in renal cancer]. Vojnosanitetski pregled. 2008 Nov; 65(11):820-4. doi: 10.2298/vsp0811820z. [PMID: 19069712]
  • Nedeljko Radlović, Dragana Janić, Silvija Sajić, Srdja Janković, Maja Jesić, Zoran Leković, Rada Petrović. [IPEX syndrome--case report]. Srpski arhiv za celokupno lekarstvo. 2008 Sep; 136(9-10):538-41. doi: 10.2298/sarh0810538r. [PMID: 19069348]
  • J John, H R Cama. Metabolism and biological activity of citroxanthin (mutatochrome) in rat. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition. 1972; 42(2):278-84. doi: NULL. [PMID: 5053853]