Isorhoifolin (BioDeep_00000871791)

Main id: BioDeep_00000017576

 

human metabolite PANOMIX_OTCML-2023


代谢物信息卡片


5-hydroxy-2-(4-hydroxyphenyl)-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-4H-chromen-4-one

化学式: C27H30O14 (578.163548)
中文名称: 异氟林
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: c1(cc(c2c(c1)oc(cc2=O)c1ccc(cc1)O)O)O[C@H]1[C@H]([C@H]([C@@H]([C@H](O1)CO[C@H]1[C@H]([C@H]([C@H]([C@@H](O1)C)O)O)O)O)O)O
InChI: InChI=1S/C27H30O14/c1-10-20(31)22(33)24(35)26(38-10)37-9-18-21(32)23(34)25(36)27(41-18)39-13-6-14(29)19-15(30)8-16(40-17(19)7-13)11-2-4-12(28)5-3-11/h2-8,10,18,20-29,31-36H,9H2,1H3/t10-,18+,20-,21+,22+,23-,24+,25+,26+,27+/m0/s1

描述信息

Apigenin 8-c-rhamnosyl-glucoside, also known as isorhoifoline or apigenin-7-O-rutinoside, is a member of the class of compounds known as flavonoid-7-o-glycosides. Flavonoid-7-o-glycosides are phenolic compounds containing a flavonoid moiety which is O-glycosidically linked to carbohydrate moiety at the C7-position. Apigenin 8-c-rhamnosyl-glucoside is slightly soluble (in water) and a very weakly acidic compound (based on its pKa). Apigenin 8-c-rhamnosyl-glucoside can be found in oat, which makes apigenin 8-c-rhamnosyl-glucoside a potential biomarker for the consumption of this food product.
Isorhoifolin is found in citrus. Isorhoifolin is isolated from leaves of Citrus paradisi (grapefruit) and other plant species.
Isorhoifolin is a flavonoid glycoside from Hemistepta lyrata. Isorhoifolin displays an anti-leakage effect[1][2].
Isorhoifolin is a flavonoid glycoside from Hemistepta lyrata. Isorhoifolin displays an anti-leakage effect[1][2].

同义名列表

27 个代谢物同义名

5-hydroxy-2-(4-hydroxyphenyl)-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-4H-chromen-4-one; 5-hydroxy-2-(4-hydroxyphenyl)-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}methyl)oxan-2-yl]oxy}chromen-4-one; Apigenin 7-O-beta-D-glucopyranosyl-(6->1)-alpha-L-rhamnopyranoside; Apigenin 7-O-alpha-L-rhamnopyranosyl-(1->6)-beta-D-glucopyranoside; Apigenin 7-O-α-L-rhamnopyranosyl-(1→6)-beta-D-glucopyranoside; Apigenin 7-O-beta-D-glucopyranosyl-(6→1)-α-L-rhamnopyranoside; Apigenin 7-O-alpha-L-rhamnosyl-(1->6)-beta-D-glucopyranoside; Apigenin 7-O-β-D-glucopyranosyl-(6→1)-α-L-rhamnopyranoside; Apigenin 7-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside; Apigenin 7-O-α-L-rhamnosyl-(1→6)-beta-D-glucopyranoside; Apigenin 7-O-α-L-rhamnosyl-(1→6)-β-D-glucopyranoside; 5,7,4’-trihydroxyflavone 7-O-rutinoside; 5,7,4-TRIHYDROXYFLAVONE 7-O-RUTINOSIDE; Apigenin-7-O-gluco(6’-1’’’) rhamnoside; APIGENIN-7-O-GLUCO(6-1) RHAMNOSIDE; Apigenin 8-C-rhamnosyl-glucoside; Apigenin-7-O-beta-D-rutinoside; Apigenin 7-O-beta-rutinoside; Apigenin-7-O-β-D-rutinoside; Apigenin 7-beta-rutinoside; apigenin-7-O-rutinoside; Apigenin 7-O-rutinoside; Apigenin 7-β-rutinoside; Apigenin 7-rutinoside; Apigenin-7-rutinoside; Isorhoifoline; Isorhoifolin



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

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PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

25 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Sachiko Sugimoto, Yoshi Yamano, Samar Y Desoukey, Kazuaki Katakawa, Amira S Wanas, Hideaki Otsuka, Katsuyoshi Matsunami. Isolation of Sesquiterpene-Amino Acid Conjugates, Onopornoids A-D, and a Flavonoid Glucoside from Onopordum alexandrinum. Journal of natural products. 2019 06; 82(6):1471-1477. doi: 10.1021/acs.jnatprod.8b00948. [PMID: 31199638]
  • Gülin Renda, Büşra Korkmaz, Merve Kılıç, Mine Kadıoğlu Duman, Hasan Kırmızıbekmez. Evaluation of in vivo analgesic activity of Scrophularia kotscyhana and isolation of bioactive compounds through activity-guided fractionation. Natural product research. 2018 Aug; 32(16):1902-1910. doi: 10.1080/14786419.2017.1356829. [PMID: 28758426]
  • Medine Gulluce, Furkan Orhan, Ahmet Adiguzel, Tugba Bal, Zuhal Guvenalp, Lutfiye Omur Dermirezer. Determination of antimutagenic properties of apigenin-7-O-rutinoside, a flavonoid isolated from Mentha longifolia (L.) Huds. ssp. longifolia with yeast DEL assay. Toxicology and industrial health. 2013 Jul; 29(6):534-40. doi: 10.1177/0748233712442732. [PMID: 22491724]
  • Ozlem Baris, Mehmet Karadayi, Derya Yanmis, Zuhal Guvenalp, Tugba Bal, Medine Gulluce. Isolation of 3 flavonoids from Mentha longifolia (L.) Hudson subsp. longifolia and determination of their genotoxic potentials by using the E. coli WP2 test system. Journal of food science. 2011 Nov; 76(9):T212-7. doi: 10.1111/j.1750-3841.2011.02405.x. [PMID: 22416730]
  • Bui Huu Tai, Nguyen Xuan Nhiem, Tran Hong Quang, Nguyen Thi Thanh Ngan, Nguyen Huu Tung, Yohan Kim, Jung-Jin Lee, Chang-Seon Myung, Nguyen Manh Cuong, Young Ho Kim. A new iridoid and effect on the rat aortic vascular smooth muscle cell proliferation of isolated compounds from Buddleja officinalis. Bioorganic & medicinal chemistry letters. 2011 Jun; 21(11):3462-6. doi: 10.1016/j.bmcl.2011.03.078. [PMID: 21524582]
  • Ying Zhou, Yan Wang, Renfeng Wang, Fei Guo, Chao Yan. Two-dimensional liquid chromatography coupled with mass spectrometry for the analysis of Lobelia chinensis Lour. using an ESI/APCI multimode ion source. Journal of separation science. 2008 Jul; 31(13):2388-94. doi: 10.1002/jssc.200700685. [PMID: 18604839]
  • Mingfu Wang, James E Simon, Irma Fabiola Aviles, Kan He, Qun-Yi Zheng, Yaakov Tadmor. Analysis of antioxidative phenolic compounds in artichoke (Cynara scolymus L.). Journal of agricultural and food chemistry. 2003 Jan; 51(3):601-8. doi: 10.1021/jf020792b. [PMID: 12537429]