Nigakihemiacetal B (BioDeep_00000000672)

 

Secondary id: BioDeep_00001867537, BioDeep_00001878055

human metabolite PANOMIX_OTCML-2023 Endogenous natural product


代谢物信息卡片


11-hydroxy-4,15-dimethoxy-2,6,14,17-tetramethyl-10-oxatetracyclo[7.7.1.0²,⁷.0¹³,¹⁷]heptadeca-4,14-diene-3,16-dione

化学式: C22H30O6 (390.204228)
中文名称: 新苦木苷
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 33.33%

分子结构信息

SMILES: C1(=C[C@@H]([C@H]2[C@](C1=O)([C@@H]1[C@]3([C@@H](C2)O[C@@H](C[C@H]3C(=C(C1=O)OC)C)O)C)C)C)OC
InChI: InChI=1S/C22H30O6/c1-10-7-14(26-5)20(25)22(4)12(10)8-15-21(3)13(9-16(23)28-15)11(2)18(27-6)17(24)19(21)22/h7,10,12-13,15-16,19,23H,8-9H2,1-6H3

描述信息

Nigakihemiacetal B is a constituent of Quassia amara (Surinam quassia)
Constituent of Quassia amara (Surinam quassia)
Neoquassin is a triterpenoid.

同义名列表

12 个代谢物同义名

11-hydroxy-4,15-dimethoxy-2,6,14,17-tetramethyl-10-oxatetracyclo[7.7.1.0²,⁷.0¹³,¹⁷]heptadeca-4,14-diene-3,16-dione; Picrasa-2,12-diene-1,11-dione, 16-hydroxy-2,12-dimethoxy-; 16-Hydroxy-2,12-dimethoxy-picrasa-2,12-diene-1,11-dione; hydroxy-dimethoxy-tetramethyl-[?]dione; Simalikahemiacetal A; Nigakihemiacetal B; NEOQUASSIN [MI]; UNII-9MQ0P9426V; Neoquassine; 9MQ0P9426V; Neoquassin; Neoquassin



数据库引用编号

23 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

16 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Yuzo Nishizaki, Atsuko Tada, Kyoko Ishizuki, Yusai Ito, Aya Onoda, Naoki Sugimoto, Hiroshi Akiyama. [Development of a Novel Method for Quantifying Quassin and Neoquassin in Jamaica Quassia Extracts Using the Molar Absorption Coefficient Ratio]. Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan. 2015; 56(5):185-93. doi: 10.3358/shokueishi.56.185. [PMID: 26537647]
  • Kirti Mishra, Dipjyoti Chakraborty, Amita Pal, Nrisingha Dey. Plasmodium falciparum: in vitro interaction of quassin and neo-quassin with artesunate, a hemisuccinate derivative of artemisinin. Experimental parasitology. 2010 Apr; 124(4):421-7. doi: 10.1016/j.exppara.2009.12.007. [PMID: 20036657]
  • Emeline Houël, Stéphane Bertani, Geneviève Bourdy, Eric Deharo, Valérie Jullian, Alexis Valentin, Séverine Chevalley, Didier Stien. Quassinoid constituents of Quassia amara L. leaf herbal tea. Impact on its antimalarial activity and cytotoxicity. Journal of ethnopharmacology. 2009 Oct; 126(1):114-8. doi: 10.1016/j.jep.2009.07.037. [PMID: 19665539]
  • Mario Shields, Umar Niazi, Simone Badal, Trevor Yee, Michael J Sutcliffe, Rupika Delgoda. Inhibition of CYP1A1 by Quassinoids found in Picrasma excelsa. Planta medica. 2009 Feb; 75(2):137-41. doi: 10.1055/s-0028-1088350. [PMID: 19016402]
  • Atsuko Tada, Naoki Sugimoto, Kyoko Sato, Takumi Akiyama, Masaharu Asanoma, Young Sook Yun, Takeshi Yamazaki, Kenichi Tanamoto. [Examination of original plant of Jamaica quassia extract, a natural bittering agent, based on composition of the constituents]. Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan. 2009 Feb; 50(1):16-21. doi: 10.3358/shokueishi.50.16. [PMID: 19325221]
  • Naoki Sugimoto, Kyoko Sato, Takeshi Yamazaki, Kenichi Tanamoto. [Analysis of constituents in Jamaica quassia extract, a natural bittering agent]. Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan. 2003 Dec; 44(6):328-31. doi: 10.3358/shokueishi.44.328. [PMID: 15038116]