ST 29:2;O2 (BioDeep_00000636752)

 

Secondary id: BioDeep_00000005348, BioDeep_00000008698, BioDeep_00001873500


代谢物信息卡片


(25R)-5alpha,6alpha-epoxy-24R,26R-dimethyl-26,27-cyclo-cholestan-3beta-ol

化学式: C29H48O2 (428.36541079999995)
中文名称: 胆固醇乙酸酯
谱图信息: 最多检出来源 Homo sapiens(lipidomics) 0.34%

分子结构信息

SMILES: C12CC[C@@]3([H])[C@](C)(C=O)[C@@H](O)CC[C@]3(C)C=1CC[C@]1(C)[C@@]([H])([C@@](C)([H])CCCC(C)C)CC[C@@]21[H]
InChI: InChI=1S/C29H48O2/c1-19(2)8-7-9-20(3)25-12-13-26-24-11-10-22-18-23(31-21(4)30)14-16-28(22,5)27(24)15-17-29(25,26)6/h10,19-20,23-27H,7-9,11-18H2,1-6H3/t20-,23+,24+,25-,26+,27+,28+,29-/m1/s1

描述信息

同义名列表

28 个代谢物同义名

3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carbaldehyde; ST 29:2;O2; (25R)-5alpha,6alpha-epoxy-24R,26R-dimethyl-26,27-cyclo-cholestan-3beta-ol; 5,6alpha-epoxy-petrosterol; Poriferasta-5,25-dien-3beta,22-ol; 22-hydroxyclerosterol; 24Z-ethylidene-cholest-5-en-3beta,22S-diol; 22S-hydroxyisofucosterol; 3beta-hydroxy-stigmast-5-en-7-one; 24S,28S-epoxystigmast-5-en-3beta-ol; (3beta,24S,24S)-fucosterol epoxide; (3beta,24S,28S)-fucosterol epoxide; (24R,24R)-Fucosterol epoxide;(24R,28R)-Fucosterol epoxide; (24R,28R)-24,28-epoxystigmast-5-en-3beta-ol; 24R,28R-epoxystigmast-5-en-3beta-ol; (3beta,24R,24R)-fucosterol epoxide; 4alpha-Methyl-5alpha-cholest-22E,24(28)-dien-3beta,8beta-diol; 23R,24R-dimethylcholest-5,17(20)-dien-3beta,16alpha-diol; 16alpha-hydroxy-sarcosterol; 23R-Methyl-ergosta-5,17(20)-diene-3beta,16beta-diol; Klyflaccisteroid B; 23R-Methyl-ergosta-5,20(21)-diene-3beta,17alpha-diol; Klyflaccisteroid A; 3beta-acetoxycholest-5-ene; (-)-Cholesteryl acetate; Cholesteryl acetate; 4alpha-hydroxymethyl-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol; 4alpha-formyl-4beta-methyl-5alpha-cholesta-8-en-3beta-ol



数据库引用编号

45 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(7)

PlantCyc(0)

代谢反应

1 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(1)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

18 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

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  • Mehmet Nail Nasir, Françoise Besson. Conformational analyses of bacillomycin D, a natural antimicrobial lipopeptide, alone or in interaction with lipid monolayers at the air-water interface. Journal of colloid and interface science. 2012 Dec; 387(1):187-93. doi: 10.1016/j.jcis.2012.07.091. [PMID: 22967349]
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  • Vineet Choudhary, Roger Schneiter. Pathogen-Related Yeast (PRY) proteins and members of the CAP superfamily are secreted sterol-binding proteins. Proceedings of the National Academy of Sciences of the United States of America. 2012 Oct; 109(42):16882-7. doi: 10.1073/pnas.1209086109. [PMID: 23027975]
  • Peter Y Wielinga, Gopala K Yakala, Peter Heeringa, Robert Kleemann, Teake Kooistra. Beneficial effects of alternate dietary regimen on liver inflammation, atherosclerosis and renal activation. PloS one. 2011 Mar; 6(3):e18432. doi: 10.1371/journal.pone.0018432. [PMID: 21483792]
  • Magdalena M Domon, Gladys Matar, Agnieszka Strzelecka-Kiliszek, Joanna Bandorowicz-Pikula, Slawomir Pikula, Françoise Besson. Interaction of annexin A6 with cholesterol rich membranes is pH-dependent and mediated by the sterol OH. Journal of colloid and interface science. 2010 Jun; 346(2):436-41. doi: 10.1016/j.jcis.2010.03.015. [PMID: 20363475]
  • Robert Kleemann, Marjan van Erk, Lars Verschuren, Anita M van den Hoek, Maud Koek, Peter Y Wielinga, Annie Jie, Linette Pellis, Ivana Bobeldijk-Pastorova, Thomas Kelder, Karin Toet, Suzan Wopereis, Nicole Cnubben, Chris Evelo, Ben van Ommen, Teake Kooistra. Time-resolved and tissue-specific systems analysis of the pathogenesis of insulin resistance. PloS one. 2010 Jan; 5(1):e8817. doi: 10.1371/journal.pone.0008817. [PMID: 20098690]
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  • Elena Bonzón-Kulichenko, Dominik Schwudke, Nilda Gallardo, Eduardo Moltó, Teresa Fernández-Agulló, Andrej Shevchenko, Antonio Andrés. Central leptin regulates total ceramide content and sterol regulatory element binding protein-1C proteolytic maturation in rat white adipose tissue. Endocrinology. 2009 Jan; 150(1):169-78. doi: 10.1210/en.2008-0505. [PMID: 18801905]
  • Chisato Ishimaru, Isoko Kuriyama, Noriko Shimazaki, Osamu Koiwai, Kengo Sakaguchi, Ikuo Kato, Hiromi Yoshida, Yoshiyuki Mizushina. Cholesterol hemisuccinate: a selective inhibitor of family X DNA polymerases. Biochemical and biophysical research communications. 2007 Mar; 354(2):619-25. doi: 10.1016/j.bbrc.2007.01.034. [PMID: 17241613]
  • Heng-Ling Liou, Sayali S Dixit, Sujuan Xu, G Stephen Tint, Ann M Stock, Peter Lobel. NPC2, the protein deficient in Niemann-Pick C2 disease, consists of multiple glycoforms that bind a variety of sterols. The Journal of biological chemistry. 2006 Dec; 281(48):36710-23. doi: 10.1074/jbc.m608743200. [PMID: 17018531]
  • Katja Rebolj, Natasa Poklar Ulrih, Peter Macek, Kristina Sepcić. Steroid structural requirements for interaction of ostreolysin, a lipid-raft binding cytolysin, with lipid monolayers and bilayers. Biochimica et biophysica acta. 2006 Oct; 1758(10):1662-70. doi: 10.1016/j.bbamem.2006.06.003. [PMID: 16857161]
  • Dmitry A Aleksandrov, Anna N Zagryagskaya, Marina A Pushkareva, Markus Bachschmid, Marc Peters-Golden, Oliver Werz, Dieter Steinhilber, Galina F Sud'ina. Cholesterol and its anionic derivatives inhibit 5-lipoxygenase activation in polymorphonuclear leukocytes and MonoMac6 cells. The FEBS journal. 2006 Feb; 273(3):548-57. doi: 10.1111/j.1742-4658.2005.05087.x. [PMID: 16420478]
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