Octaprenyl diphosphate (BioDeep_00000005424)
Secondary id: BioDeep_00001869074
human metabolite Endogenous natural product
代谢物信息卡片
化学式: C40H68O7P2 (722.4440038000001)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 0.53%
分子结构信息
SMILES: CC(=CCCC(=CCCC(=CCCC(=CCCC(=CCCC(=CCCC(=CCCC(=CCOP(=O)(O)OP(=O)(O)O)C)C)C)C)C)C)C)C
InChI: InChI=1S/C40H68O7P2/c1-33(2)17-10-18-34(3)19-11-20-35(4)21-12-22-36(5)23-13-24-37(6)25-14-26-38(7)27-15-28-39(8)29-16-30-40(9)31-32-46-49(44,45)47-48(41,42)43/h17,19,21,23,25,27,29,31H,10-16,18,20,22,24,26,28,30,32H2,1-9H3,(H,44,45)(H2,41,42,43)/b34-19+,35-21+,36-23+,37-25+,38-27+,39-29+,40-31+
描述信息
Octaprenyl diphosphate, also known as farnesylfarnesylgeraniol or OPP, belongs to the class of organic compounds known as tetraterpenoids. These are terpenoid molecules containing 10 consecutively linked isoprene units. Octaprenyl diphosphate is the precursor for the side chain of the isoprenoid quinones ubiquinone and menaquinone. It is a substrate of the enzyme trans-octaprenyltranstransferase (EC 2.5.1.11) in the steroid biosynthesis pathway.
Octaprenyl diphosphate is the precursor for the side chain of the isoprenoid quinones ubiquinone and menaquinone. It is a substrate of enzyme trans-octaprenyltranstransferase [EC 2.5.1.11] in biosynthesis of steroids pathway (KEGG). [HMDB]. Octaprenyl diphosphate is found in many foods, some of which are macadamia nut (m. tetraphylla), brazil nut, maitake, and dill.
同义名列表
11 个代谢物同义名
{[hydroxy({[(2E,6E,10E,14E,18E,22E,26E)-3,7,11,15,19,23,27,31-octamethyldotriaconta-2,6,10,14,18,22,26,30-octaen-1-yl]oxy})phosphoryl]oxy}phosphonic acid; (2E,6E,10E,14E,18E,22E,26E)-3,7,11,15,19,23,27,31-OCTAMETHYLDOTRIACONTA-2,6,10,14,18,22,26,30-octaenyl trihydrogen diphosphoric acid; (2E,6E,10E,14E,18E,22E,26E)-3,7,11,15,19,23,27,31-OCTAMETHYLDOTRIACONTA-2,6,10,14,18,22,26,30-octaenyl trihydrogen diphosphATE; all-trans-Octaprenyl pyrophosphoric acid; all-trans-Octaprenyl pyrophosphate; all-trans-Octaprenyl diphosphate; Octaprenyl diphosphoric acid; Octaprenyl pyrophosphate; Farnesylfarnesylgeraniol; Octaprenyl diphosphate; OPP
数据库引用编号
18 个数据库交叉引用编号
- ChEBI: CHEBI:16275
- ChEBI: CHEBI:53045
- KEGG: C04146
- PubChem: 5280651
- PubChem: 708
- HMDB: HMDB0001094
- Metlin: METLIN6000
- MetaCyc: OCTAPRENYL-DIPHOSPHATE
- foodb: FDB022423
- chemspider: 4444251
- CAS: 64732-94-1
- PMhub: MS000018225
- PubChem: 6831
- LipidMAPS: LMPR01070226
- PDB-CCD: OTP
- 3DMET: B01721
- NIKKAJI: J2.167.537G
- LOTUS: LTS0132140
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
12 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(5)
- polyisoprenoid biosynthesis (E. coli):
(2E,6E)-farnesyl diphosphate + isopentenyl diphosphate ⟶ di-trans,poly-cis-undecaprenyl diphosphate + diphosphate
- octaprenyl diphosphate biosynthesis:
(2E,6E)-farnesyl diphosphate + isopentenyl diphosphate ⟶ all-trans-octaprenyl diphosphate + diphosphate
- polyisoprenoid biosynthesis (E. coli):
geranyl diphosphate + isopentenyl diphosphate ⟶ (2E,6E)-farnesyl diphosphate + diphosphate
- ubiquinol-8 biosynthesis (prokaryotic):
3-octaprenyl-4-hydroxybenzoate + H+ ⟶ 2-octaprenylphenol + CO2
- octaprenyl diphosphate biosynthesis:
(2E,6E)-farnesyl diphosphate + isopentenyl diphosphate ⟶ all-trans-octaprenyl diphosphate + diphosphate
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(7)
- Secondary Metabolites: Methylerythritol Phosphate and Polyisoprenoid Biosynthesis:
1-Deoxy-D-xylulose 5-phosphate + Hydrogen Ion + NADPH ⟶ 2-C-methyl-D-erythritol 4-phosphate + NADP
- Secondary Metabolites: Ubiquinol Biosynthesis:
2-Octaprenylphenol + Hydrogen Ion + NADPH + Oxygen ⟶ 2-Octaprenyl-6-hydroxyphenol + NADP + Water
- Menaquinol Biosythesis:
2-succinylbenzoate + Adenosine triphosphate + Coenzyme A ⟶ 2-Succinylbenzoyl-CoA + Adenosine monophosphate + Pyrophosphate
- Secondary Metabolites: Ubiquinol Biosynthesis 2:
2-Octaprenylphenol + Hydrogen Ion + NADPH + Oxygen ⟶ 2-Octaprenyl-6-hydroxyphenol + NADP + Water
- Secondary Metabolites: Methylerythritol Phosphate and Polyisoprenoid Biosynthesis:
4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol + Adenosine triphosphate ⟶ 2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol + Adenosine diphosphate + Hydrogen Ion
- Secondary Metabolites: Ubiquinol Biosynthesis:
Chorismate ⟶ 4-Hydroxybenzoic acid + Pyruvic acid
- Secondary Metabolites: Ubiquinol Biosynthesis 2:
Chorismate ⟶ 4-Hydroxybenzoic acid + Pyruvic acid
PharmGKB(0)
9 个相关的物种来源信息
- 7458 - Apidae: LTS0132140
- 7459 - Apis: LTS0132140
- 7461 - Apis cerana: 10.1371/JOURNAL.PONE.0175573
- 7461 - Apis cerana: LTS0132140
- 6656 - Arthropoda: LTS0132140
- 2759 - Eukaryota: LTS0132140
- 9606 - Homo sapiens: -
- 50557 - Insecta: LTS0132140
- 33208 - Metazoa: LTS0132140
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- O Leiva, F Lozano, C Ramos, P Paniagua, V Borobia. [Diagnosis of renal angiomyolipoma by means of computerized axial tomography].
Actas urologicas espanolas.
1979 Jan; 3(1):43-6. doi:
NULL
. [PMID: 452977]