Ginkgotoxin (BioDeep_00000017639)

 

Secondary id: BioDeep_00000615681

human metabolite PANOMIX_OTCML-2023 Endogenous natural product


代谢物信息卡片


5-Hydroxy-4-(methoxymethyl)-6-methyl-3-pyridinemethanol, 9CI

化学式: C9H13NO3 (183.0895388)
中文名称: 5-羟基-4-甲氧甲基-6-甲基-3-吡啶甲醇, 5-羟基-4-甲氧甲基-6-甲基-3-吡啶甲醇
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 15.38%

分子结构信息

SMILES: CC1=NC=C(C(=C1O)COC)CO
InChI: InChI=1S/C9H13NO3/c1-6-9(12)8(5-13-2)7(4-11)3-10-6/h3,11-12H,4-5H2,1-2H3

描述信息

Ginkgotoxin is a member of pyridines.
5-(Hydroxymethyl)-4-(methoxymethyl)-2-methylpyridin-3-ol is a natural product found in Ginkgo biloba with data available.
Ginkgotoxin is found in fats and oils. Ginkgotoxin is isolated from seeds of maidenhair tree Ginkgo bilob
4'-O-Methylpyridoxine, a natural compound, possesses antioxidant activity[1].
4'-O-Methylpyridoxine, a natural compound, possesses antioxidant activity[1].

同义名列表

27 个代谢物同义名

5-Hydroxy-4-(methoxymethyl)-6-methyl-3-pyridinemethanol, 9CI; 3-HYDROXY-5-HYDROXYMETHYL-4-METHOXYMETHYL-2-METHYLPYRIDINE; 5-(hydroxymethyl)-4-(methoxymethyl)-2-methyl-pyridin-3-ol; 3-Pyridinemethanol, 5-hydroxy-4-(methoxymethyl)-6-methyl-; 5-(Hydroxymethyl)-4-(methoxymethyl)-2-methylpyridin-3-ol; 5-Hydroxy-4-(methoxymethyl)-6-methyl-3-pyridinemethanol; 5-Hydroxymethyl-4-methoxymethyl-2-methyl-pyridin-3-ol; 5-21-05-00494 (Beilstein Handbook Reference); 4-methoxymethylpyridoxine hydrochloride; 4-O-Methylpyridoxine (Ginkgotoxin); Ginkgotoxin, analytical standard; .alpha.(sup 4)-O-Methylpyridoxol; alpha(sup 4)-O-Methylpyridoxol; SVINQHQHARVZFF-UHFFFAOYSA-N; 4-methoxymethylpyridoxine; alpha4-O-Methylpyridoxol; 4-O-methoxypyridoxine; 4-O-methylpyridoxine; 4-O-Methylpyridoxine; 4-Methoxypyridoxine; 4-methoxypyridoxine; UNII-BSN7F3YJ95; Ginkgotoxin; BSN7F3YJ95; 4en4; GT0; 4'-O-Methylpyridoxine



数据库引用编号

15 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

18 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Teris A van Beek, Paola Montoro. Chemical analysis and quality control of Ginkgo biloba leaves, extracts, and phytopharmaceuticals. Journal of chromatography. A. 2009 Mar; 1216(11):2002-32. doi: 10.1016/j.chroma.2009.01.013. [PMID: 19195661]
  • Shunji Hasegawa, Yasutaka Oda, Takashi Ichiyama, Yasushi Hori, Susumu Furukawa. Ginkgo nut intoxication in a 2-year-old male. Pediatric neurology. 2006 Oct; 35(4):275-6. doi: 10.1016/j.pediatrneurol.2006.05.008. [PMID: 16996402]
  • Yasushi Hori, Manami Fujisawa, Kenji Shimada, Akira Oda, Shinichiro Katsuyama, Keiji Wada. Rapid analysis of 4-O-methylpyridoxine in the serum of patients with Ginkgo biloba seed poisoning by ion-pair high-performance liquid chromatography. Biological & pharmaceutical bulletin. 2004 Apr; 27(4):486-91. doi: 10.1248/bpb.27.486. [PMID: 15056852]
  • Xiaosuo Wang, Vimal Kapoor, George A Smythe. Extraction and chromatography-mass spectrometric analysis of the active principles from selected Chinese herbs and other medicinal plants. The American journal of Chinese medicine. 2003; 31(6):927-44. doi: 10.1142/s0192415x0300165x. [PMID: 14992545]
  • Manami Fujisawa, Yasushi Hori, Mariko Nakajima, Kenji Shimada, Hideto Yoshikawa, Keiji Wada. Gas chromatography-mass spectrometry analysis of 4-O-methylpyridoxine (MPN) in the serum of patients with ginkgo seed poisoning. Journal of analytical toxicology. 2002 Apr; 26(3):138-43. doi: 10.1093/jat/26.3.138. [PMID: 11991529]
  • Yo Kajiyama, Kenichi Fujii, Hajime Takeuchi, Yutaka Manabe. Ginkgo seed poisoning. Pediatrics. 2002 Feb; 109(2):325-7. doi: 10.1542/peds.109.2.325. [PMID: 11826216]
  • M Fujisawa, M Nakajima, Y Hori, K Shimada, H Yoshikawa, K Wada, M Haga. [Determination of 4-O-methylpyridoxine (MPN) by HPLC with diode-array detector]. Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology. 2001 Apr; 14(2):127-32. doi: NULL. [PMID: 11505497]
  • K Fiehe, A Arenz, C Drewke, T Hemscheidt, R T Williamson, E Leistner. Biosynthesis of 4'-O-methylpyridoxine (Ginkgotoxin) from primary precursors. Journal of natural products. 2000 Feb; 63(2):185-9. doi: 10.1021/np990414+. [PMID: 10691705]
  • M Yagi, K Wada, M Sakata, M Kokubo, M Haga. [Studies on the constituents of edible and medicinal plants. IV. Determination of 4-O-methylpyridoxine in serum of the patient with gin-nan food poisoning]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 1993 Aug; 113(8):596-9. doi: 10.1248/yakushi1947.113.8_596. [PMID: 8377108]
  • N Mizuno, M Fukumoto-Hato, M Matsumoto-Yoshino, E Morita. Stability, bactericidal activity, vitamin B6 activity and gastrointestinal absorption of benzoic acid esters of pyridoxine. Journal of nutritional science and vitaminology. 1981; 27(3):165-75. doi: 10.3177/jnsv.27.165. [PMID: 6793703]