7-(3,7-Dimethylocta-2,6-dienoxy)-1-benzopyran-2-one (BioDeep_00000173808)

   

human metabolite blood metabolite natural product


代谢物信息卡片


7-[(3,7-dimethylocta-2,6-dien-1-yl)oxy]-2H-chromen-2-one

化学式: C19H22O3 (298.15688620000003)
中文名称:
谱图信息: 最多检出来源 Mus musculus(blood) 83.33%

分子结构信息

SMILES: CC(C)=CCCC(C)=CCOC1=CC=C2C=CC(=O)OC2=C1
InChI: InChI=1S/C19H22O3/c1-14(2)5-4-6-15(3)11-12-21-17-9-7-16-8-10-19(20)22-18(16)13-17/h5,7-11,13H,4,6,12H2,1-3H3

描述信息

同义名列表

3 个代谢物同义名

7-[(3,7-dimethylocta-2,6-dien-1-yl)oxy]-2H-chromen-2-one; 7-[(3,7-dimethylocta-2,6-dien-1-yl)oxy]chromen-2-one; 7-(3,7-dimethylocta-2,6-dienoxy)-1-benzopyran-2-one



数据库引用编号

4 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

176 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Hirotaka Sekiguchi, Fumiyo Takabayashi, Kazuhiro Irie, Akira Murakami. Auraptene attenuates gastritis via reduction of Helicobacter pylori colonization and pro-inflammatory mediator production in C57BL/6 mice. Journal of medicinal food. 2012 Jul; 15(7):658-63. doi: 10.1089/jmf.2011.1844. [PMID: 22471969]
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  • Nobuyuki Takahashi, Mari Senda, Shan Lin, Tsuyoshi Goto, Masamichi Yano, Takao Sasaki, Shigeru Murakami, Teruo Kawada. Auraptene regulates gene expression involved in lipid metabolism through PPARα activation in diabetic obese mice. Molecular nutrition & food research. 2011 Dec; 55(12):1791-7. doi: 10.1002/mnfr.201100401. [PMID: 22038981]
  • Yan-Gang Li, Hai-Fang Chen, Ming-Zhu Tu, Pu-Zhao Zhang, Xiao-Yun Wang, Jin-Bin Yuan, Wu-Liang Yang. Identification, synthesis and quantification of process-related impurities in auraptene. Journal of pharmaceutical and biomedical analysis. 2011 Sep; 56(2):191-9. doi: 10.1016/j.jpba.2011.05.011. [PMID: 21705169]
  • Tsuyoshi Goto, Hiroyuki Nagai, Kahori Egawa, Young-Il Kim, Sota Kato, Aki Taimatsu, Tomoya Sakamoto, Shogo Ebisu, Takahiro Hohsaka, Hiroh Miyagawa, Shigeru Murakami, Nobuyuki Takahashi, Teruo Kawada. Farnesyl pyrophosphate regulates adipocyte functions as an endogenous PPARγ agonist. The Biochemical journal. 2011 Aug; 438(1):111-9. doi: 10.1042/bj20101939. [PMID: 21605082]
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  • Noriyuki Nakayama, Katsunori Yamaura, Maki Shimada, Koichi Ueno. Extract from peel of Citrus natsudaidai alleviates experimental chronic allergic dermatitis in mice. Pharmacognosy research. 2011 Jul; 3(3):155-9. doi: 10.4103/0974-8490.84999. [PMID: 22022162]
  • Helge Joa, Sylvia Vogl, Atanas G Atanasov, Martin Zehl, Thomas Nakel, Nanang Fakhrudin, Elke H Heiss, Paolo Picker, Ernst Urban, Christoph Wawrosch, Johannes Saukel, Gottfried Reznicek, Brigitte Kopp, Verena M Dirsch. Identification of ostruthin from Peucedanum ostruthium rhizomes as an inhibitor of vascular smooth muscle cell proliferation. Journal of natural products. 2011 Jun; 74(6):1513-6. doi: 10.1021/np200072a. [PMID: 21627108]
  • Tsuyoshi Goto, Joo-Young Lee, Aki Teraminami, Yong-Il Kim, Shizuka Hirai, Taku Uemura, Hiroyasu Inoue, Nobuyuki Takahashi, Teruo Kawada. Activation of peroxisome proliferator-activated receptor-alpha stimulates both differentiation and fatty acid oxidation in adipocytes. Journal of lipid research. 2011 May; 52(5):873-84. doi: 10.1194/jlr.m011320. [PMID: 21324916]
  • Bo Kyung Min, Dong Geol Hyun, Su Yang Jeong, Young Ho Kim, Eun Sook Ma, Mi Hee Woo. A new cytotoxic coumarin, 7-[(E)-3',7'-dimethyl-6'-oxo-2',7'-octadienyl] oxy coumarin, from the leaves of Zanthoxylum schinifolium. Archives of pharmacal research. 2011 May; 34(5):723-6. doi: 10.1007/s12272-011-0504-6. [PMID: 21656356]
  • Eric M Sciullo, Christoph F Vogel, Dalei Wu, Akira Murakami, Hajime Ohigashi, Fumio Matsumura. Effects of selected food phytochemicals in reducing the toxic actions of TCDD and p,p'-DDT in U937 macrophages. Archives of toxicology. 2010 Dec; 84(12):957-66. doi: 10.1007/s00204-010-0592-y. [PMID: 20865247]
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  • Tsuyoshi Goto, Nobuyuki Takahashi, Shizuka Hirai, Teruo Kawada. Various Terpenoids Derived from Herbal and Dietary Plants Function as PPAR Modulators and Regulate Carbohydrate and Lipid Metabolism. PPAR research. 2010; 2010(?):483958. doi: 10.1155/2010/483958. [PMID: 20613991]
  • Hirotaka Sekiguchi, Kazuhiro Irie, Akira Murakami. Suppression of CD74 expression and Helicobacter pylori adhesion by auraptene targeting serum starvation-activated ERK1/2 in NCI-N87 gastric carcinoma cells. Bioscience, biotechnology, and biochemistry. 2010; 74(5):1018-24. doi: 10.1271/bbb.90910. [PMID: 20460732]
  • Shizuka Hirai, Nobuyuki Takahashi, Tsuyoshi Goto, Shan Lin, Taku Uemura, Rina Yu, Teruo Kawada. Functional food targeting the regulation of obesity-induced inflammatory responses and pathologies. Mediators of inflammation. 2010; 2010(?):367838. doi: 10.1155/2010/367838. [PMID: 20508825]
  • Thaïs B César, John A Manthey, Kyung Myung. Minor furanocoumarins and coumarins in grapefruit peel oil as inhibitors of human cytochrome P450 3A4. Journal of natural products. 2009 Sep; 72(9):1702-4. doi: 10.1021/np900266m. [PMID: 19689106]
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  • Kayo Kuroyanagi, Min-Sook Kang, Tsuyoshi Goto, Shizuka Hirai, Kana Ohyama, Tatsuya Kusudo, Rina Yu, Masamichi Yano, Takao Sasaki, Nobuyuki Takahashi, Teruo Kawada. Citrus auraptene acts as an agonist for PPARs and enhances adiponectin production and MCP-1 reduction in 3T3-L1 adipocytes. Biochemical and biophysical research communications. 2008 Feb; 366(1):219-25. doi: 10.1016/j.bbrc.2007.11.119. [PMID: 18060855]
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  • Nobuyuki Takahashi, Min-Sook Kang, Kayo Kuroyanagi, Tsuyoshi Goto, Shizuka Hirai, Kana Ohyama, Joo-Young Lee, Rina Yu, Masamichi Yano, Takao Sasaki, Shigeru Murakami, Teruo Kawada. Auraptene, a citrus fruit compound, regulates gene expression as a PPARalpha agonist in HepG2 hepatocytes. BioFactors (Oxford, England). 2008; 33(1):25-32. doi: 10.1002/biof.5520330103. [PMID: 19276534]
  • Do Y Jun, Jun S Kim, Hae S Park, Cho R Han, Zhe Fang, Mi H Woo, In K Rhee, Young H Kim. Apoptogenic activity of auraptene of Zanthoxylum schinifolium toward human acute leukemia Jurkat T cells is associated with ER stress-mediated caspase-8 activation that stimulates mitochondria-dependent or -independent caspase cascade. Carcinogenesis. 2007 Jun; 28(6):1303-13. doi: 10.1093/carcin/bgm028. [PMID: 17301064]
  • MingXi Tang, Kumiko Ogawa, Makoto Asamoto, Naomi Hokaiwado, Azman Seeni, Shugo Suzuki, Satoru Takahashi, Takuji Tanaka, Kazuhito Ichikawa, Tomoyuki Shirai. Protective effects of citrus nobiletin and auraptene in transgenic rats developing adenocarcinoma of the prostate (TRAP) and human prostate carcinoma cells. Cancer science. 2007 Apr; 98(4):471-7. doi: 10.1111/j.1349-7006.2007.00417.x. [PMID: 17284254]
  • Mehrdad Iranshahi, Peyman Arfa, Mohammad Ramezani, Mahmoud Reza Jaafari, Hamid Sadeghian, Carla Bassarello, Sonia Piacente, Cosimo Pizza. Sesquiterpene coumarins from Ferula szowitsiana and in vitro antileishmanial activity of 7-prenyloxycoumarins against promastigotes. Phytochemistry. 2007 Feb; 68(4):554-61. doi: 10.1016/j.phytochem.2006.11.002. [PMID: 17196626]
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