2,4-Diamino-6-nitrotoluene (BioDeep_00000011160)

 

Secondary id: BioDeep_00001876734

human metabolite


代谢物信息卡片


4-Methyl-5-nitrobenzene-1,3-diamine

化学式: C7H9N3O2 (167.0695)
中文名称: 4-甲基-5-硝基苯-1,3-二胺
谱图信息: 最多检出来源 Homo sapiens(lipidsearch) 15.61%

分子结构信息

SMILES: CC1=C(C=C(C=C1[N+](=O)[O-])N)N
InChI: InChI=1S/C7H9N3O2/c1-4-6(9)2-5(8)3-7(4)10(11)12/h2-3H,8-9H2,1H3

描述信息

This compound belongs to the family of Nitrobenzenes. These are compounds containing a nitrobenzene moiety, which consists of a benzene ring with a carbon bearing a nitro group.

同义名列表

4 个代谢物同义名

4-Methyl-5-nitrobenzene-1,3-diamine; 2,4-Diamino-6-nitrotoluene; 2-Nitro-4,6-diaminotoluene; 2,4-Diamino-6-nitrotoluene



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Nucleus 1 PRM1
cytosol 1 PRM1
nucleoplasm 1 PRM1
Chromosome 1 PRM1
nucleosome 1 PRM1


文献列表

  • Youping Deng, Sharon A Meyer, Xin Guan, Barbara Lynn Escalon, Junmei Ai, Mitchell S Wilbanks, Ruth Welti, Natàlia Garcia-Reyero, Edward J Perkins. Analysis of common and specific mechanisms of liver function affected by nitrotoluene compounds. PloS one. 2011 Feb; 6(2):e14662. doi: 10.1371/journal.pone.0014662. [PMID: 21346803]
  • Christopher F Hoehamer, N Lee Wolfe, Karl Erik L Eriksson. Biotransformation of 2,4,6-trinitrotoluene (TNT) by the fungus Fusarium oxysporum. International journal of phytoremediation. 2006; 8(2):95-105. doi: 10.1080/15226510600678423. [PMID: 16924959]
  • Christopher F Hoehamer, N Lee Wolfe, Karl Erik L Eriksson. Differences in the biotransformation of 2,4,6-trinitrotoluene (TNT) between wild and axenically grown isolates of Myriophyllum aquaticum. International journal of phytoremediation. 2006; 8(2):107-15. doi: 10.1080/15226510600678431. [PMID: 16924960]
  • M A Moteleb, M T Suidan, J Kim, J L Davel, N R Adrian. Anaerobic degradation of 2,4,6-trinitrotoluene in granular activated carbon fluidized bed and batch reactors. Water science and technology : a journal of the International Association on Water Pollution Research. 2001; 43(1):67-75. doi: . [PMID: 11379114]
  • J L Martin, S D Comfort, P J Shea, T A Kokjohn, R A Drijber. Denitration of 2,4,6-trinitrotoluene by Pseudomonas savastanoi. Canadian journal of microbiology. 1997 May; 43(5):447-55. doi: 10.1139/m97-063. [PMID: 9198535]
  • L Pucik, J Hughes. Capillary electrophoretic separation of TNT and its transformation products. Journal of capillary electrophoresis. 1996 Jul; 3(4):209-13. doi: ". [PMID: 9384739]
  • J Yinon, D G Hwang. Identification of urinary metabolites of 2,4,6-trinitrotoluene in rats by liquid chromatography-mass spectometry. Toxicology letters. 1985 Aug; 26(2-3):205-9. doi: 10.1016/0378-4274(85)90168-7. [PMID: 3839946]
  • S Husted, T Hjort. Sperm antibodies in serum and seminal plasma. International journal of fertility. 1975; 20(2):97-105. doi: NULL. [PMID: 3485]