2,3-dinor-8-iso-PGF2a (BioDeep_00000010147)

Main id: BioDeep_00000629120

 


代谢物信息卡片


(Z)-5-[(1S,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentyl]pent-3-enoic acid

化学式: C18H30O5 (326.209313)
中文名称: 2,3-dinor-8-iso Prostaglandin F2α
谱图信息: 最多检出来源 Viridiplantae(plant) 5%

分子结构信息

SMILES: CCCCCC(C=CC1C(CC(C1CC=CCC(=O)O)O)O)O
InChI: InChI=1S/C18H30O5/c1-2-3-4-7-13(19)10-11-15-14(16(20)12-17(15)21)8-5-6-9-18(22)23/h5-6,10-11,13-17,19-21H,2-4,7-9,12H2,1H3,(H,22,23)/b6-5-,11-10+/t13-,14-,15+,16-,17+/m0/s1

描述信息

同义名列表

9 个代谢物同义名

(Z)-5-[(1S,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentyl]pent-3-enoic acid; 9S,11R,15S-trihydroxy-2,3-dinor-5Z,13E-prostadienoic acid-cyclo[8S,12R]; 2,3-dinor-11beta-Prostaglandin F2alpha; 2,3-dinor-8-epi-prostaglandin F2alpha; 2,3-Dinor-8-iso prostaglandin F2alpha; 2,3-DI-NOR-8-ISOPROSTAGLANDIN F2A; 2,3-Dinor-8-iso PGF2alpha; 2,3-Dinor-8-iso-PGF2alpha; 2,3-dinor-8-iso-PGF2a



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Yusuke Miyazaki, Tatsuro Nakamura, Shinya Takenouchi, Akane Hayashi, Keisuke Omori, Takahisa Murata. Urinary 8-iso PGF2α and 2,3-dinor-8-iso PGF2α can be indexes of colitis-associated colorectal cancer in mice. PloS one. 2021; 16(1):e0245292. doi: 10.1371/journal.pone.0245292. [PMID: 33503019]
  • Maryam Miraghajani, Nafiseh Zaghian, Maryam Mirlohi, Awat Feizi, Reza Ghiasvand. The Impact of Probiotic Soy Milk Consumption on Oxidative Stress Among Type 2 Diabetic Kidney Disease Patients: A Randomized Controlled Clinical Trial. Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation. 2017 09; 27(5):317-324. doi: 10.1053/j.jrn.2017.04.004. [PMID: 28579313]
  • Haoyue Zhang, Dora Il'yasova, Judit Sztaray, Sarah P Young, Frances Wang, David S Millington. Quantification of the oxidative damage biomarker 2,3-dinor-8-isoprostaglandin-F(2alpha) in human urine using liquid chromatography-tandem mass spectrometry. Analytical biochemistry. 2010 Apr; 399(2):302-4. doi: 10.1016/j.ab.2009.12.024. [PMID: 20026293]
  • Jaffar Nourooz-Zadeh, Christoph G Sohr, Thierry Durand, Dan Ziegler. Impact of diabetic polyneuropathy and cardiovascular autonomic neuropathy on the excretion of urinary 8-epi-PGF2alpha and its metabolites (2, 3-dinor and 2, 3-dinor-5, 6-dihydro). Free radical research. 2006 Jul; 40(7):723-9. doi: 10.1080/10715760600615086. [PMID: 16983999]
  • J Nourooz-Zadeh, M B Cooper, D Ziegler, D J Betteridge. Urinary 8-epi-PGF2alpha and its endogenous beta-oxidation products (2,3-dinor and 2,3-dinor-5,6-dihydro) as biomarkers of total body oxidative stress. Biochemical and biophysical research communications. 2005 May; 330(3):731-6. doi: 10.1016/j.bbrc.2005.03.024. [PMID: 15809058]
  • Yuanling Liang, Ping Wei, Russell W Duke, Peter D Reaven, S Mitchell Harman, Richard G Cutler, Christopher B Heward. Quantification of 8-iso-prostaglandin-F(2alpha) and 2,3-dinor-8-iso-prostaglandin-F(2alpha) in human urine using liquid chromatography-tandem mass spectrometry. Free radical biology & medicine. 2003 Feb; 34(4):409-18. doi: 10.1016/s0891-5849(02)01018-3. [PMID: 12566066]