2-Aminobenzoic acid

Anthranilic acid, calcium (2:1) salt

C7H7NO2 (137.0477)


2-Aminobenzoic acid, also known as anthranilic acid or O-aminobenzoate, belongs to the class of organic compounds known as aminobenzoic acids. These are benzoic acids containing an amine group attached to the benzene moiety. Within humans, 2-aminobenzoic acid participates in a number of enzymatic reactions. In particular, 2-aminobenzoic acid and formic acid can be biosynthesized from formylanthranilic acid through its interaction with the enzyme kynurenine formamidase. In addition, 2-aminobenzoic acid and L-alanine can be biosynthesized from L-kynurenine through its interaction with the enzyme kynureninase. It is a substrate of enzyme 2-Aminobenzoic acid hydroxylase in benzoate degradation via hydroxylation pathway (KEGG). In humans, 2-aminobenzoic acid is involved in tryptophan metabolism. Outside of the human body, 2-Aminobenzoic acid has been detected, but not quantified in several different foods, such as mamey sapotes, prairie turnips, rowals, natal plums, and hyacinth beans. This could make 2-aminobenzoic acid a potential biomarker for the consumption of these foods. 2-Aminobenzoic acid is a is a tryptophan-derived uremic toxin with multidirectional properties that can affect the hemostatic system. Uremic syndrome may affect any part of the body and can cause nausea, vomiting, loss of appetite, and weight loss. Chronic exposure of uremic toxins can lead to a number of conditions including renal damage, chronic kidney disease and cardiovascular disease. It can also cause changes in mental status, such as confusion, reduced awareness, agitation, psychosis, seizures, and coma. 2-Aminobenzoic acid is an organic compound. It is a substrate of enzyme anthranilate hydroxylase [EC 1.14.13.35] in benzoate degradation via hydroxylation pathway (KEGG). [HMDB]. Anthranilic acid is found in many foods, some of which are butternut squash, sunflower, ginger, and hyssop. Acquisition and generation of the data is financially supported in part by CREST/JST. D002491 - Central Nervous System Agents > D000927 - Anticonvulsants CONFIDENCE standard compound; INTERNAL_ID 8844 CONFIDENCE standard compound; INTERNAL_ID 8009 CONFIDENCE standard compound; INTERNAL_ID 115 KEIO_ID A010

   

Deoxyeritadenine

4-(6-amino-9H-purin-9-yl)-2-hydroxybutanoic acid

C9H11N5O3 (237.0862)


Deoxyeritadenine is found in mushrooms. Deoxyeritadenine is a constituent of the edible shitake mushroom

   

2,3-Dihydro-6-methoxy-2,2-dimethyl-4H-1-benzopyran-4-one

6-methoxy-2,2-dimethyl-3,4-dihydro-2H-1-benzopyran-4-one

C12H14O3 (206.0943)


2,3-Dihydro-6-methoxy-2,2-dimethyl-4H-1-benzopyran-4-one is found in mushrooms. 2,3-Dihydro-6-methoxy-2,2-dimethyl-4H-1-benzopyran-4-one is isolated from the mushroom Lentinus crinitus (palatability not certain). Isolated from the mushroom Lentinus crinitus (palatability not certain). 2,3-Dihydro-6-methoxy-2,2-dimethyl-4H-1-benzopyran-4-one is found in mushrooms.

   

Hypnophilin

(1S,3R,6R,7R,8R,11S)-6-hydroxy-5,5,8-trimethyl-9-methylidene-12-oxatetracyclo[6.4.0.01,11.03,7]dodecan-10-one

C15H20O3 (248.1412)


[Raw Data] CBA38_Hypnophilin_pos_40eV_1-3_01_1725.txt [Raw Data] CBA38_Hypnophilin_pos_30eV_1-3_01_1724.txt [Raw Data] CBA38_Hypnophilin_pos_20eV_1-3_01_1723.txt [Raw Data] CBA38_Hypnophilin_pos_10eV_1-3_01_1714.txt

   

5-(Hydroxymethyl)furan-3-carboxylic acid

5-(Hydroxymethyl)furan-3-carboxylic acid

C6H6O4 (142.0266)


   

2-aminobenzoic acid

2-aminobenzoic acid

C7H7NO2 (137.0477)


MS2 deconvoluted using MS2Dec from all ion fragmentation data, MetaboLights identifier MTBLS1040; RWZYAGGXGHYGMB-UHFFFAOYSA-N_STSL_0017_Anthranilic Acid_8000fmol_180410_S2_LC02_MS02_91; Spectrum acquired as described in Naz et al 2017 PMID 28641411. Preparation and submission to MassBank of North America by Chaleckis R. and Tada I. MS2 deconvoluted using CorrDec from all ion fragmentation data, MetaboLights identifier MTBLS1040; Spectrum acquired as described in Naz et al 2017 PMID 28641411. Preparation and submission to MassBank of North America by Chaleckis R. and Tada I.

   

Dormin

(2E,4E)-5-(1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl)-3-methylpenta-2,4-dienoic acid

C15H20O4 (264.1362)


D020011 - Protective Agents > D000975 - Antioxidants > D002338 - Carotenoids D006133 - Growth Substances > D010937 - Plant Growth Regulators (±)-Abscisic acid is an orally active plant hormone that is present also in animals. (±)-Abscisic acid (ABA) contributes to the regulation of glycemia in mammals[1]. (±)-Abscisic acid is an orally active plant hormone that is present also in animals. (±)-Abscisic acid (ABA) contributes to the regulation of glycemia in mammals[1]. Abscisic acid ((S)-(+)-Abscisic acid), an orally active phytohormone in fruits and vegetables, is an endogenously produced mammalian hormone. Abscisic acid is a growth inhibitor and can regulate many aspects of plant growth and development. Abscisic acid inhibits proton pump (H+-ATPase) and leads to the plasma membrane depolarization in a Ca2+-dependent manner. Abscisic acid, a LANCL2 natural ligand, is a potent insulin-sensitizing compound and has the potential for pre-diabetes, type 2 diabetes and metabolic syndrome[1][2]. Abscisic acid ((S)-(+)-Abscisic acid), an orally active phytohormone in fruits and vegetables, is an endogenously produced mammalian hormone. Abscisic acid is a growth inhibitor and can regulate many aspects of plant growth and development. Abscisic acid inhibits proton pump (H+-ATPase) and leads to the plasma membrane depolarization in a Ca2+-dependent manner. Abscisic acid, a LANCL2 natural ligand, is a potent insulin-sensitizing compound and has the potential for pre-diabetes, type 2 diabetes and metabolic syndrome[1][2].

   

Deoxyeritadenine

4-(6-amino-9H-purin-9-yl)-2-hydroxybutanoic acid

C9H11N5O3 (237.0862)


   

6-Methoxy-2,2-dimethyl-4-chromanone

2,3-Dihydro-6-methoxy-2,2-dimethyl-4H-1-benzopyran-4-one

C12H14O3 (206.0943)


   

6-methoxy-2,2-dimethyl-3,4-dihydro-2H-1-benzopyran-4-one

6-methoxy-2,2-dimethyl-3,4-dihydro-2H-1-benzopyran-4-one

C12H14O3 (206.0943)


   

5,5,8-trimethyl-9-methylidene-12-oxatetracyclo[6.4.0.0¹,¹¹.0³,⁷]dodecan-10-ol

5,5,8-trimethyl-9-methylidene-12-oxatetracyclo[6.4.0.0¹,¹¹.0³,⁷]dodecan-10-ol

C15H22O2 (234.162)


   

(4s)-6-methoxy-2,2-dimethyl-3,4-dihydro-1-benzopyran-4-ol

(4s)-6-methoxy-2,2-dimethyl-3,4-dihydro-1-benzopyran-4-ol

C12H16O3 (208.1099)


   

(4e)-5-[(1s)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid

(4e)-5-[(1s)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid

C15H20O4 (264.1362)


   

(1r,2s,3s,8s,11r)-3,11-dihydroxy-3-(hydroxymethyl)-2,10,10-trimethyltricyclo[6.3.0.0²,⁶]undec-5-en-4-one

(1r,2s,3s,8s,11r)-3,11-dihydroxy-3-(hydroxymethyl)-2,10,10-trimethyltricyclo[6.3.0.0²,⁶]undec-5-en-4-one

C15H22O4 (266.1518)


   

1-[(2,5,5,8a-tetramethyl-1,4,4a,6,7,8-hexahydronaphthalen-1-yl)methoxy]propane-1,2,3-tricarboxylic acid

1-[(2,5,5,8a-tetramethyl-1,4,4a,6,7,8-hexahydronaphthalen-1-yl)methoxy]propane-1,2,3-tricarboxylic acid

C21H32O7 (396.2148)


   

(1r,2s)-1-{[(1s,4as,8as)-5,5,8a-trimethyl-2-methylidene-hexahydro-1h-naphthalen-1-yl]methoxy}propane-1,2,3-tricarboxylic acid

(1r,2s)-1-{[(1s,4as,8as)-5,5,8a-trimethyl-2-methylidene-hexahydro-1h-naphthalen-1-yl]methoxy}propane-1,2,3-tricarboxylic acid

C21H32O7 (396.2148)


   

(1r,2s)-1-{[(1s,4as,8as)-2,5,5,8a-tetramethyl-1,4,4a,6,7,8-hexahydronaphthalen-1-yl]methoxy}propane-1,2,3-tricarboxylic acid

(1r,2s)-1-{[(1s,4as,8as)-2,5,5,8a-tetramethyl-1,4,4a,6,7,8-hexahydronaphthalen-1-yl]methoxy}propane-1,2,3-tricarboxylic acid

C21H32O7 (396.2148)


   

(1s,5r,6s)-5-hydroxy-3-[(1s)-1-hydroxy-3-methylbut-2-en-1-yl]-7-oxabicyclo[4.1.0]hept-3-en-2-one

(1s,5r,6s)-5-hydroxy-3-[(1s)-1-hydroxy-3-methylbut-2-en-1-yl]-7-oxabicyclo[4.1.0]hept-3-en-2-one

C11H14O4 (210.0892)


   

3,11-dihydroxy-3-(hydroxymethyl)-2,10,10-trimethyltricyclo[6.3.0.0²,⁶]undec-5-en-4-one

3,11-dihydroxy-3-(hydroxymethyl)-2,10,10-trimethyltricyclo[6.3.0.0²,⁶]undec-5-en-4-one

C15H22O4 (266.1518)


   

(1s,5r,6s)-5-hydroxy-3-(1-hydroxy-3-methylbut-2-en-1-yl)-7-oxabicyclo[4.1.0]hept-3-en-2-one

(1s,5r,6s)-5-hydroxy-3-(1-hydroxy-3-methylbut-2-en-1-yl)-7-oxabicyclo[4.1.0]hept-3-en-2-one

C11H14O4 (210.0892)


   

(1s,2s,3s,6s,8r)-1,4,4-trimethyl-11-methylidene-9-azatricyclo[6.3.1.0²,⁶]dodec-9-ene-3,8,10-triol

(1s,2s,3s,6s,8r)-1,4,4-trimethyl-11-methylidene-9-azatricyclo[6.3.1.0²,⁶]dodec-9-ene-3,8,10-triol

C15H23NO3 (265.1678)


   

5,5,8-trimethyl-9-methylidene-12-oxatetracyclo[6.4.0.0¹,¹¹.0³,⁷]dodecan-10-one

5,5,8-trimethyl-9-methylidene-12-oxatetracyclo[6.4.0.0¹,¹¹.0³,⁷]dodecan-10-one

C15H20O2 (232.1463)


   

1-[(6s,7s)-6,7-dihydroxy-3,6-dimethyl-5,7-dihydro-4h-1-benzofuran-2-yl]-3-methylbutan-1-one

1-[(6s,7s)-6,7-dihydroxy-3,6-dimethyl-5,7-dihydro-4h-1-benzofuran-2-yl]-3-methylbutan-1-one

C15H22O4 (266.1518)


   

(1r,2r,6s,8r,11r)-4,6,11-trihydroxy-2,3,10,10-tetramethyltricyclo[6.3.0.0²,⁶]undec-3-en-5-one

(1r,2r,6s,8r,11r)-4,6,11-trihydroxy-2,3,10,10-tetramethyltricyclo[6.3.0.0²,⁶]undec-3-en-5-one

C15H22O4 (266.1518)


   

4,6,11-trihydroxy-2,3,10,10-tetramethyltricyclo[6.3.0.0²,⁶]undec-3-en-5-one

4,6,11-trihydroxy-2,3,10,10-tetramethyltricyclo[6.3.0.0²,⁶]undec-3-en-5-one

C15H22O4 (266.1518)


   

(2r,3r,4r,5r)-6-methylheptane-1,2,3,4,5-pentol

(2r,3r,4r,5r)-6-methylheptane-1,2,3,4,5-pentol

C8H18O5 (194.1154)


   

6-methylheptane-1,2,3,4,5-pentol

6-methylheptane-1,2,3,4,5-pentol

C8H18O5 (194.1154)


   

(1s,6r)-3-[(1r)-1-hydroxy-3-methylbut-2-en-1-yl]-7-oxabicyclo[4.1.0]hept-3-ene-2,5-dione

(1s,6r)-3-[(1r)-1-hydroxy-3-methylbut-2-en-1-yl]-7-oxabicyclo[4.1.0]hept-3-ene-2,5-dione

C11H12O4 (208.0736)


   

2-[(5,5,8a-trimethyl-2-methylidene-hexahydro-1h-naphthalen-1-yl)methoxy]-3-(methoxycarbonyl)pentanedioic acid

2-[(5,5,8a-trimethyl-2-methylidene-hexahydro-1h-naphthalen-1-yl)methoxy]-3-(methoxycarbonyl)pentanedioic acid

C22H34O7 (410.2304)


   

(1s,5r,6s)-5-hydroxy-3-[(1r)-1-hydroxy-3-methylbut-2-en-1-yl]-7-oxabicyclo[4.1.0]hept-3-en-2-one

(1s,5r,6s)-5-hydroxy-3-[(1r)-1-hydroxy-3-methylbut-2-en-1-yl]-7-oxabicyclo[4.1.0]hept-3-en-2-one

C11H14O4 (210.0892)


   

3-(1-hydroxy-3-methylbut-2-en-1-yl)-7-oxabicyclo[4.1.0]hept-3-ene-2,5-dione

3-(1-hydroxy-3-methylbut-2-en-1-yl)-7-oxabicyclo[4.1.0]hept-3-ene-2,5-dione

C11H12O4 (208.0736)


   

(1s,3r,6r,7r,8r,10r,11r)-5,5,8-trimethyl-9-methylidene-12-oxatetracyclo[6.4.0.0¹,¹¹.0³,⁷]dodecane-6,10-diol

(1s,3r,6r,7r,8r,10r,11r)-5,5,8-trimethyl-9-methylidene-12-oxatetracyclo[6.4.0.0¹,¹¹.0³,⁷]dodecane-6,10-diol

C15H22O3 (250.1569)


   

(1r,2s)-1-{[(1s,4ar,6s,8as)-6-hydroxy-2,5,5,8a-tetramethyl-1,4,4a,6,7,8-hexahydronaphthalen-1-yl]methoxy}propane-1,2,3-tricarboxylic acid

(1r,2s)-1-{[(1s,4ar,6s,8as)-6-hydroxy-2,5,5,8a-tetramethyl-1,4,4a,6,7,8-hexahydronaphthalen-1-yl]methoxy}propane-1,2,3-tricarboxylic acid

C21H32O8 (412.2097)


   

1-[(5,5,8a-trimethyl-2-methylidene-hexahydro-1h-naphthalen-1-yl)methoxy]propane-1,2,3-tricarboxylic acid

1-[(5,5,8a-trimethyl-2-methylidene-hexahydro-1h-naphthalen-1-yl)methoxy]propane-1,2,3-tricarboxylic acid

C21H32O7 (396.2148)


   

5,5,8-trimethyl-9-methylidene-12-oxatetracyclo[6.4.0.0¹,¹¹.0³,⁷]dodecane-6,10-diol

5,5,8-trimethyl-9-methylidene-12-oxatetracyclo[6.4.0.0¹,¹¹.0³,⁷]dodecane-6,10-diol

C15H22O3 (250.1569)


   

5-hydroxy-3-(1-hydroxy-3-methylbut-2-en-1-yl)-7-oxabicyclo[4.1.0]hept-3-en-2-one

5-hydroxy-3-(1-hydroxy-3-methylbut-2-en-1-yl)-7-oxabicyclo[4.1.0]hept-3-en-2-one

C11H14O4 (210.0892)


   

(6s,7r,7as)-6,7-dihydroxy-3,6-dimethyl-4,5,7,7a-tetrahydro-1-benzofuran-2-one

(6s,7r,7as)-6,7-dihydroxy-3,6-dimethyl-4,5,7,7a-tetrahydro-1-benzofuran-2-one

C10H14O4 (198.0892)


   

(2r,3s)-2-{[(1s,4as,8as)-5,5,8a-trimethyl-2-methylidene-hexahydro-1h-naphthalen-1-yl]methoxy}-3-(methoxycarbonyl)pentanedioic acid

(2r,3s)-2-{[(1s,4as,8as)-5,5,8a-trimethyl-2-methylidene-hexahydro-1h-naphthalen-1-yl]methoxy}-3-(methoxycarbonyl)pentanedioic acid

C22H34O7 (410.2304)


   

(1s,3r,7r,8r,10r,11r)-5,5,8-trimethyl-9-methylidene-12-oxatetracyclo[6.4.0.0¹,¹¹.0³,⁷]dodecan-10-ol

(1s,3r,7r,8r,10r,11r)-5,5,8-trimethyl-9-methylidene-12-oxatetracyclo[6.4.0.0¹,¹¹.0³,⁷]dodecan-10-ol

C15H22O2 (234.162)


   

(1s,3r,7r,8r,11s)-5,5,8-trimethyl-9-methylidene-12-oxatetracyclo[6.4.0.0¹,¹¹.0³,⁷]dodecan-10-one

(1s,3r,7r,8r,11s)-5,5,8-trimethyl-9-methylidene-12-oxatetracyclo[6.4.0.0¹,¹¹.0³,⁷]dodecan-10-one

C15H20O2 (232.1463)


   

1-[(6-hydroxy-2,5,5,8a-tetramethyl-1,4,4a,6,7,8-hexahydronaphthalen-1-yl)methoxy]propane-1,2,3-tricarboxylic acid

1-[(6-hydroxy-2,5,5,8a-tetramethyl-1,4,4a,6,7,8-hexahydronaphthalen-1-yl)methoxy]propane-1,2,3-tricarboxylic acid

C21H32O8 (412.2097)