NCBI Taxonomy: 29309

Bleomycin B2

C55H84N20O21S2 (1424.5561054000002)

C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C259 - Antineoplastic Antibiotic C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C2842 - DNA Binding Agent D000970 - Antineoplastic Agents

Bleomycin

C55H84N17O21S3+ (1414.5189554)

A complex of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and B2 (B2 CAS # 9060-10-0). It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors. Bleomycin A2 is used as the representative structure for Bleomycin. L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01D - Cytotoxic antibiotics and related substances C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C259 - Antineoplastic Antibiotic C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C2842 - DNA Binding Agent D000970 - Antineoplastic Agents

Sulfur

S8 (255.776576)

Sulfur or sulphur is the chemical element with atomic number 16, represented by the symbol S. At normal conditions, sulfur atoms form cyclic octatomic molecules with chemical formula S8. Elemental sulfur is a bright yellow crystalline solid. In nature, sulfur can be found as the pure element and as sulfide and sulfate minerals. Sulfur is an essential element for all life, and is widely used in biochemical processes. Sulfur in organic form is present in the vitamins biotin and thiamine. Sulfur is an important part of many enzymes and also in antioxidant molecules like glutathione and thioredoxin. Organically bonded sulfur is a component of all proteins, as the amino acids cysteine and methionine. Disulfide bonds are largely responsible for the mechanical strength and insolubility of the protein keratin, found in outer skin, hair, and feathers, and the element contributes to their pungent odor when burned.

Bleomycin A2

C55H84N17O21S3+ (1414.5189554)

L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01D - Cytotoxic antibiotics and related substances D000970 - Antineoplastic Agents

2-{2-[2-({2-[(4-{[2-({[2-(1-{[2-amino-2-(c-hydroxycarbonimidoyl)ethyl]amino}-2-(c-hydroxycarbonimidoyl)ethyl)-6-imino-5-methyl-1h-pyrimidin-4-yl](hydroxy)methylidene}amino)-3-[(3-{[3,5-dihydroxy-4-(c-hydroxycarbonimidoyloxy)-6-(hydroxymethyl)oxan-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl)oxy]-1-hydroxy-3-(3h-imidazol-4-yl)propylidene]amino}-1,3-dihydroxy-2-methylpentylidene)amino]-1,3-dihydroxybutylidene}amino)ethyl]-1,3-thiazol-4-yl}-n-{3-[(4-aminobutyl)amino]propyl}-1,3-thiazole-4-carboximidic acid

C57H89N19O21S2 (1439.5921544000003)

(3s,4s,5r,6r)-4,5-dihydroxy-6-[(1-hydroxyethylidene)amino]piperidine-3-carboxylic acid

C8H14N2O5 (218.09026740000002)

2-[2-(2-{[(2r,3s)-2-{[(2r,3s,4s)-4-{[(2s,3s)-2-[({2-[(1s)-1-{[(2r)-2-amino-2-(c-hydroxycarbonimidoyl)ethyl]amino}-2-(c-hydroxycarbonimidoyl)ethyl]-6-imino-5-methyl-1h-pyrimidin-4-yl}(hydroxy)methylidene)amino]-3-{[(2r,3r,4r,5s,6s)-3-{[(2s,3r,4r,5r,6r)-3,5-dihydroxy-4-(c-hydroxycarbonimidoyloxy)-6-(hydroxymethyl)oxan-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-1-hydroxy-3-(3h-imidazol-4-yl)propylidene]amino}-1,3-dihydroxy-2-methylpentylidene]amino}-1,3-dihydroxybutylidene]amino}ethyl)-1,3-thiazol-4-yl]-n-[3-(methylsulfanyl)propyl]-1,3-thiazole-4-carboximidic acid

C54H81N17O21S3 (1399.4954816000002)

2-[2-(2-{[(2r)-2-{[(2s,3s,4r)-4-{[(2r,3s)-2-[({2-[(1r)-1-{[(2r)-2-amino-2-(c-hydroxycarbonimidoyl)ethyl]amino}-2-(c-hydroxycarbonimidoyl)ethyl]-6-imino-5-methyl-1h-pyrimidin-4-yl}(hydroxy)methylidene)amino]-3-{[(2r,3r,4s,5r,6s)-3-{[(2r,3r,4s,5r,6r)-3,5-dihydroxy-4-(c-hydroxycarbonimidoyloxy)-6-(hydroxymethyl)oxan-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-1-hydroxy-3-(3h-imidazol-4-yl)propylidene]amino}-1,3-dihydroxy-2-methylpentylidene]amino}-1-hydroxy-2-(1-hydroxycyclopropyl)ethylidene]amino}ethyl)-1,3-thiazol-4-yl]-n-(4-carbamimidamidobutyl)-1,3-thiazole-4-carboximidic acid

C56H84N20O21S2 (1436.5561054000002)

(3-{[(2-{2-[2-({2-[(4-{[2-({[2-(1-{[2-amino-2-(c-hydroxycarbonimidoyl)ethyl]amino}-2-(c-hydroxycarbonimidoyl)ethyl)-6-imino-5-methyl-1h-pyrimidin-4-yl](hydroxy)methylidene}amino)-3-[(3-{[3,5-dihydroxy-4-(c-hydroxycarbonimidoyloxy)-6-(hydroxymethyl)oxan-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl)oxy]-1-hydroxy-3-(3h-imidazol-4-yl)propylidene]amino}-1,3-dihydroxy-2-methylpentylidene)amino]-1,3-dihydroxybutylidene}amino)ethyl]-1,3-thiazol-4-yl}-1,3-thiazol-4-yl)(hydroxy)methylidene]amino}propyl)dimethylsulfanium

[C55H84N17O21S3]+ (1414.5189554)

{3-[({2-[2-(2-{[(2s,3r)-2-{[(2s,3s,4r)-4-{[(2s,3r)-2-[({2-[(1s)-1-{[(2s)-2-amino-2-(c-hydroxycarbonimidoyl)ethyl]amino}-2-(c-hydroxycarbonimidoyl)ethyl]-6-imino-5-methyl-1h-pyrimidin-4-yl}(hydroxy)methylidene)amino]-3-[(3-{[3,5-dihydroxy-4-(c-hydroxycarbonimidoyloxy)-6-(hydroxymethyl)oxan-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl)oxy]-1-hydroxy-3-(3h-imidazol-4-yl)propylidene]amino}-1,3-dihydroxy-2-methylpentylidene]amino}-1,3-dihydroxybutylidene]amino}ethyl)-1,3-thiazol-4-yl]-1,3-thiazol-4-yl}(hydroxy)methylidene)amino]propyl}dimethylsulfanium

[C55H84N17O21S3]+ (1414.5189554)

2-[2-(2-{[(2s,3r)-2-{[(2s,3s,4r)-4-{[(2s,3r)-2-[({2-[(1s)-1-{[(2s)-2-amino-2-(c-hydroxycarbonimidoyl)ethyl]amino}-2-(c-hydroxycarbonimidoyl)ethyl]-6-imino-5-methyl-1h-pyrimidin-4-yl}(hydroxy)methylidene)amino]-3-{[(2r,3s,4s,5s,6s)-3-{[(2r,3s,4s,5r,6r)-3,5-dihydroxy-4-(c-hydroxycarbonimidoyloxy)-6-(hydroxymethyl)oxan-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-1-hydroxy-3-(3h-imidazol-4-yl)propylidene]amino}-1,3-dihydroxy-2-methylpentylidene]amino}-1,3-dihydroxybutylidene]amino}ethyl)-1,3-thiazol-4-yl]-n-[3-({4-[(3-aminopropyl)amino]butyl}amino)propyl]-1,3-thiazole-4-carboximidic acid

C60H96N20O21S2 (1496.6500006)

2-[2-(2-{[(2r,3s)-2-{[(2r,3s,4s)-4-{[(2s,3s)-2-[({2-[(1s)-1-{[(2r)-2-amino-2-(c-hydroxycarbonimidoyl)ethyl]amino}-2-(c-hydroxycarbonimidoyl)ethyl]-6-imino-5-methyl-1h-pyrimidin-4-yl}(hydroxy)methylidene)amino]-3-{[(2r,3r,4r,5s,6s)-3-{[(2s,3r,4r,5r,6r)-3,5-dihydroxy-4-(c-hydroxycarbonimidoyloxy)-6-(hydroxymethyl)oxan-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-1-hydroxy-3-(3h-imidazol-4-yl)propylidene]amino}-1,3-dihydroxy-2-methylpentylidene]amino}-1,3-dihydroxybutylidene]amino}ethyl)-1,3-thiazol-4-yl]-n-(4-aminobutyl)-1,3-thiazole-4-carboximidic acid

C54H82N18O21S2 (1382.5343082000002)

2-[2-(2-{[(2r,3s)-2-{[(2r,3s,4s)-4-{[(2s,3s)-2-[({2-[(1s)-1-{[(2r)-2-amino-2-(c-hydroxycarbonimidoyl)ethyl]amino}-2-(c-hydroxycarbonimidoyl)ethyl]-6-imino-5-methyl-1h-pyrimidin-4-yl}(hydroxy)methylidene)amino]-3-{[(2r,3r,4r,5s,6s)-3-{[(2s,3r,4r,5r,6r)-3,5-dihydroxy-4-(c-hydroxycarbonimidoyloxy)-6-(hydroxymethyl)oxan-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-1-hydroxy-3-(3h-imidazol-4-yl)propylidene]amino}-1,3-dihydroxy-2-methylpentylidene]amino}-1,3-dihydroxybutylidene]amino}ethyl)-1,3-thiazol-4-yl]-1,3-thiazole-4-carboximidic acid

C50H73N17O21S2 (1311.4608128)

2-[2-(2-{[(2s,3r)-2-{[(2s,3s,4r)-4-{[(2s,3r)-2-[({2-[(1s)-1-{[(2s)-2-amino-2-(c-hydroxycarbonimidoyl)ethyl]amino}-2-(c-hydroxycarbonimidoyl)ethyl]-6-imino-5-methyl-1h-pyrimidin-4-yl}(hydroxy)methylidene)amino]-3-{[(2r,3s,4s,5s,6s)-3-{[(2r,3s,4s,5r,6r)-3,5-dihydroxy-4-(c-hydroxycarbonimidoyloxy)-6-(hydroxymethyl)oxan-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-1-hydroxy-3-(3h-imidazol-4-yl)propylidene]amino}-1,3-dihydroxy-2-methylpentylidene]amino}-1,3-dihydroxybutylidene]amino}ethyl)-1,3-thiazol-4-yl]-n-(4-carbamimidamidobutyl)-1,3-thiazole-4-carboximidic acid

C55H84N20O21S2 (1424.5561054000002)

{3-[({2-[2-(2-{[(2s,3r)-2-{[(2s,3s,4r)-4-{[(2s,3r)-2-[({2-[(1s)-1-{[(2s)-2-amino-2-(c-hydroxycarbonimidoyl)ethyl]amino}-2-(c-hydroxycarbonimidoyl)ethyl]-6-imino-5-methyl-1h-pyrimidin-4-yl}(hydroxy)methylidene)amino]-3-{[(2r,3s,4s,5s,6s)-3-{[(2r,3s,4s,5r,6r)-3,5-dihydroxy-4-(c-hydroxycarbonimidoyloxy)-6-(hydroxymethyl)oxan-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-1-hydroxy-3-(3h-imidazol-4-yl)propylidene]amino}-1,3-dihydroxy-2-methylpentylidene]amino}-1,3-dihydroxybutylidene]amino}ethyl)-1,3-thiazol-4-yl]-1,3-thiazol-4-yl}(hydroxy)methylidene)amino]propyl}dimethylsulfanium

[C55H84N17O21S3]+ (1414.5189554)

2-[2-(2-{[(2s,3r)-2-{[(2s,3s,4r)-4-{[(2s,3r)-2-[({2-[(1s)-1-{[(2s)-2-amino-2-(c-hydroxycarbonimidoyl)ethyl]amino}-2-(c-hydroxycarbonimidoyl)ethyl]-6-imino-5-methyl-1h-pyrimidin-4-yl}(hydroxy)methylidene)amino]-3-{[(2r,3s,4s,5s,6s)-3-{[(2r,3s,4s,5r,6r)-3,5-dihydroxy-4-(c-hydroxycarbonimidoyloxy)-6-(hydroxymethyl)oxan-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-1-hydroxy-3-(3h-imidazol-4-yl)propylidene]amino}-1,3-dihydroxy-2-methylpentylidene]amino}-1,3-dihydroxybutylidene]amino}ethyl)-1,3-thiazol-4-yl]-n-(3-aminopropyl)-1,3-thiazole-4-carboximidic acid

C53H80N18O21S2 (1368.518659)

2-{2-[2-({2-[(4-{[2-({[2-(1-{[2-amino-2-(c-hydroxycarbonimidoyl)ethyl]amino}-2-(c-hydroxycarbonimidoyl)ethyl)-6-imino-5-methyl-1h-pyrimidin-4-yl](hydroxy)methylidene}amino)-3-{[(2r,3s,4s,5s,6s)-4,5-dihydroxy-6-(hydroxymethyl)-3-methyl-3-{[(2s,3r,4r,5s)-3,4,5-trihydroxy-4-(c-hydroxycarbonimidoyl)-6-(hydroxymethyl)oxan-2-yl]oxy}oxan-2-yl]oxy}-1-hydroxy-3-(3h-imidazol-4-yl)propylidene]amino}-1,3-dihydroxy-2-methylpentylidene)amino]-1-hydroxy-3-oxobutylidene}amino)ethyl]-4,5-dihydro-1,3-thiazol-4-yl}-1,3-thiazole-4-carboximidic acid

C51H75N17O21S2 (1325.476462)

2-[2-(2-{[(2r,3s)-2-{[(2r,3r,4s)-4-{[(2s,3r)-2-[({2-[(1s)-1-{[2-amino-2-(c-hydroxycarbonimidoyl)ethyl]amino}-2-(c-hydroxycarbonimidoyl)ethyl]-6-imino-5-methyl-1h-pyrimidin-4-yl}(hydroxy)methylidene)amino]-3-{[(3r,4r,5r,6r)-3-{[(2s,3r,4r,5s,6s)-3,5-dihydroxy-4-(c-hydroxycarbonimidoyloxy)-6-(hydroxymethyl)oxan-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-1-hydroxy-3-(3h-imidazol-4-yl)propylidene]amino}-1,3-dihydroxy-2-methylpentylidene]amino}-1,3-dihydroxybutylidene]amino}ethyl)-1,3-thiazol-4-yl]-n-[3-({4-[(3-aminopropyl)amino]butyl}amino)propyl]-1,3-thiazole-4-carboximidic acid

C60H96N20O21S2 (1496.6500006)

4,5-dihydroxy-6-[(1-hydroxyethylidene)amino]piperidine-3-carboxylic acid

C8H14N2O5 (218.09026740000002)

4-{[2-({[2-(1-{[2-amino-2-(c-hydroxycarbonimidoyl)ethyl]amino}-2-(c-hydroxycarbonimidoyl)ethyl)-6-imino-5-methyl-1h-pyrimidin-4-yl](hydroxy)methylidene}amino)-3-[(3-{[3,5-dihydroxy-4-(c-hydroxycarbonimidoyloxy)-6-(hydroxymethyl)oxan-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl)oxy]-1-hydroxy-3-(3h-imidazol-4-yl)propylidene]amino}-3-hydroxy-n-{2-hydroxy-1-[(2-{4-[4-({3-[(4-{[2-(c-hydroxycarbonimidoyl)ethyl]amino}butyl)amino]propyl}-c-hydroxycarbonimidoyl)-1,3-thiazol-2-yl]-1,3-thiazol-2-yl}ethyl)-c-hydroxycarbonimidoyl]propyl}-2-methylpentanimidic acid

C60H94N20O22S2 (1510.6292664)

2-[2-(2-{[(2s,3r)-2-{[(2s,3s,4s)-4-{[(2r,3r)-2-[({2-[(1r)-1-{[(2r)-2-amino-2-(c-hydroxycarbonimidoyl)ethyl]amino}-2-(c-hydroxycarbonimidoyl)ethyl]-6-imino-5-methyl-1h-pyrimidin-4-yl}(hydroxy)methylidene)amino]-3-{[(2s,3s,4r,5r,6r)-3-{[(2s,3s,4r,5s,6s)-3,5-dihydroxy-4-(c-hydroxycarbonimidoyloxy)-6-(hydroxymethyl)oxan-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-1-hydroxy-3-(3h-imidazol-4-yl)propylidene]amino}-1,3-dihydroxy-2-methylpentylidene]amino}-1,3-dihydroxybutylidene]amino}ethyl)-1,3-thiazol-4-yl]-n-[2-(3h-imidazol-4-yl)ethyl]-1,3-thiazole-4-carboximidic acid

C55H79N19O21S2 (1405.5139084)

2-{2-[2-({2-[(4-{[2-({[2-(1-{[2-amino-2-(c-hydroxycarbonimidoyl)ethyl]amino}-2-(c-hydroxycarbonimidoyl)ethyl)-6-imino-5-methyl-1h-pyrimidin-4-yl](hydroxy)methylidene}amino)-3-[(3-{[3,5-dihydroxy-4-(c-hydroxycarbonimidoyloxy)-6-(hydroxymethyl)oxan-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl)oxy]-1-hydroxy-3-(3h-imidazol-4-yl)propylidene]amino}-1,3-dihydroxy-2-methylpentylidene)amino]-1-hydroxy-2-(2-hydroxycyclopropyl)ethylidene}amino)ethyl]-1,3-thiazol-4-yl}-n-(4-carbamimidamidobutyl)-1,3-thiazole-4-carboximidic acid

C56H84N20O21S2 (1436.5561054000002)