NCBI Taxonomy: 28564

Talaromyces stipitatus (ncbi_taxid: 28564)

found 37 associated metabolites at species taxonomy rank level.

Ancestor: Talaromyces sect. Talaromyces

Child Taxonomies: Talaromyces stipitatus ATCC 10500

Emodin

1,3,8-trihydroxy-6-methyl-anthracene-9,10-dione;3-METHYL-1,6,8-TRIHYDROXYANTHRAQUINONE

C15H10O5 (270.0528)


Emodin appears as orange needles or powder. (NTP, 1992) Emodin is a trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs. It has a role as a tyrosine kinase inhibitor, an antineoplastic agent, a laxative and a plant metabolite. It is functionally related to an emodin anthrone. It is a conjugate acid of an emodin(1-). Emodin has been investigated for the treatment of Polycystic Kidney. Emodin is a natural product found in Rumex dentatus, Rhamnus davurica, and other organisms with data available. Emodin is found in dock. Emodin is present in Cascara sagrada.Emodin is a purgative resin from rhubarb, Polygonum cuspidatum, the buckthorn and Japanese Knotweed (Fallopia japonica). The term may also refer to any one of a series of principles isomeric with the emodin of rhubarb. (Wikipedia) Emodin has been shown to exhibit anti-inflammatory, signalling, antibiotic, muscle building and anti-angiogenic functions (A3049, A7853, A7854, A7855, A7857). Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as a laxative, but is now used mainly as a tool in toxicity studies. See also: Reynoutria multiflora root (part of); Frangula purshiana Bark (part of). A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs. Emodin is found in dock. Emodin is present in Cascara sagrada.Emodin is a purgative resin from rhubarb, Polygonum cuspidatum, the buckthorn and Japanese Knotweed (Fallopia japonica). The term may also refer to any one of a series of principles isomeric with the emodin of rhubarb. (Wikipedia C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor > C1967 - Tyrosine Kinase Inhibitor D004791 - Enzyme Inhibitors > D047428 - Protein Kinase Inhibitors D005765 - Gastrointestinal Agents > D002400 - Cathartics Present in Cascara sagrada CONFIDENCE standard compound; INTERNAL_ID 999; DATASET 20200303_ENTACT_RP_MIX507; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8540; ORIGINAL_PRECURSOR_SCAN_NO 8539 CONFIDENCE standard compound; INTERNAL_ID 999; DATASET 20200303_ENTACT_RP_MIX507; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8561; ORIGINAL_PRECURSOR_SCAN_NO 8559 CONFIDENCE standard compound; INTERNAL_ID 999; DATASET 20200303_ENTACT_RP_MIX507; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5082; ORIGINAL_PRECURSOR_SCAN_NO 5079 CONFIDENCE standard compound; INTERNAL_ID 999; DATASET 20200303_ENTACT_RP_MIX507; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8572; ORIGINAL_PRECURSOR_SCAN_NO 8570 CONFIDENCE standard compound; INTERNAL_ID 999; DATASET 20200303_ENTACT_RP_MIX507; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5104; ORIGINAL_PRECURSOR_SCAN_NO 5099 CONFIDENCE standard compound; INTERNAL_ID 999; DATASET 20200303_ENTACT_RP_MIX507; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8558; ORIGINAL_PRECURSOR_SCAN_NO 8556 ORIGINAL_PRECURSOR_SCAN_NO 5094; CONFIDENCE standard compound; INTERNAL_ID 999; DATASET 20200303_ENTACT_RP_MIX507; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5097 CONFIDENCE standard compound; INTERNAL_ID 999; DATASET 20200303_ENTACT_RP_MIX507; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8554; ORIGINAL_PRECURSOR_SCAN_NO 8550 CONFIDENCE standard compound; INTERNAL_ID 999; DATASET 20200303_ENTACT_RP_MIX507; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5096; ORIGINAL_PRECURSOR_SCAN_NO 5093 CONFIDENCE standard compound; INTERNAL_ID 999; DATASET 20200303_ENTACT_RP_MIX507; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8556; ORIGINAL_PRECURSOR_SCAN_NO 8554 CONFIDENCE standard compound; INTERNAL_ID 999; DATASET 20200303_ENTACT_RP_MIX507; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5090; ORIGINAL_PRECURSOR_SCAN_NO 5089 CONFIDENCE standard compound; INTERNAL_ID 999; DATASET 20200303_ENTACT_RP_MIX507; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5085; ORIGINAL_PRECURSOR_SCAN_NO 5082 CONFIDENCE standard compound; INTERNAL_ID 999; DATASET 20200303_ENTACT_RP_MIX507; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 5097; ORIGINAL_PRECURSOR_SCAN_NO 5094 [Raw Data] CB029_Emodin_pos_50eV_CB000015.txt [Raw Data] CB029_Emodin_pos_10eV_CB000015.txt [Raw Data] CB029_Emodin_pos_20eV_CB000015.txt [Raw Data] CB029_Emodin_pos_30eV_CB000015.txt [Raw Data] CB029_Emodin_pos_40eV_CB000015.txt [Raw Data] CB029_Emodin_neg_50eV_000008.txt [Raw Data] CB029_Emodin_neg_20eV_000008.txt [Raw Data] CB029_Emodin_neg_40eV_000008.txt [Raw Data] CB029_Emodin_neg_30eV_000008.txt [Raw Data] CB029_Emodin_neg_10eV_000008.txt CONFIDENCE standard compound; ML_ID 38 Emodin (Frangula emodin), an anthraquinone derivative, is an anti-SARS-CoV compound. Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 (ACE2) interaction[1]. Emodin inhibits casein kinase-2 (CK2). Anti-inflammatory and anticancer effects[2]. Emodin is a potent selective 11β-HSD1 inhibitor with the IC50 of 186 and 86 nM for human and mouse 11β-HSD1, respectively. Emodin ameliorates metabolic disorder in diet-induced obese mice[3]. Emodin (Frangula emodin), an anthraquinone derivative, is an anti-SARS-CoV compound. Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 (ACE2) interaction[1]. Emodin inhibits casein kinase-2 (CK2). Anti-inflammatory and anticancer effects[2]. Emodin is a potent selective 11β-HSD1 inhibitor with the IC50 of 186 and 86 nM for human and mouse 11β-HSD1, respectively. Emodin ameliorates metabolic disorder in diet-induced obese mice[3].

   

Stipitatate

3,6-Dihydroxy-5-oxo-1,3,6-cycloheptatriene-1-carboxylic acid

C8H6O5 (182.0215)


   

Stipitatonate

Stipitatonic acid

C9H4O6 (208.0008)


   

Botryodiplodin

1-(tetrahydro-5-Hydroxy-4-methyl-3-furanyl)ethanone, 9ci

C7H12O3 (144.0786)


Botryodiplodin is a mycotoxin produced by Botryodiplodia theobromae, Penicillium carneoluteus and Penicillium roquefortii. It is isolated from P. roquefortii infected corn silage. Mycotoxin production by Botryodiplodia theobromae, Penicillium carneoluteus and Penicillium roquefortii. Isolated from P. roquefortii infected corn silage

   
   

Erythroglaucin

Erythroglaucin

C16H12O6 (300.0634)


A trihydroxyanthraquinone that is anthracene-9,10-dione substituted by hydroxy groups at positions 1, 4 and 5, a methoxy group at position 7 and a methyl group at position 2. It has been isolated from Chaetomium globosum and other fungal species.

   
   

Stipitatic acid

Stipitatic acid

C8H6O5 (182.0215)


CONFIDENCE isolated standard

   

4-Hydroxy-6-(2-oxopropyl)-2H-pyran-2-one

4-Hydroxy-6-(2-oxopropyl)-2H-pyran-2-one

C8H8O4 (168.0423)


   

Emodin

9,10-Anthracenedione, 1,3,8-trihydroxy-6-methyl- (9CI)

C15H10O5 (270.0528)


C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor > C1967 - Tyrosine Kinase Inhibitor D004791 - Enzyme Inhibitors > D047428 - Protein Kinase Inhibitors D005765 - Gastrointestinal Agents > D002400 - Cathartics CONFIDENCE isolated standard relative retention time with respect to 9-anthracene Carboxylic Acid is 1.288 relative retention time with respect to 9-anthracene Carboxylic Acid is 1.291 relative retention time with respect to 9-anthracene Carboxylic Acid is 1.286 relative retention time with respect to 9-anthracene Carboxylic Acid is 1.293 Emodin (Frangula emodin), an anthraquinone derivative, is an anti-SARS-CoV compound. Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 (ACE2) interaction[1]. Emodin inhibits casein kinase-2 (CK2). Anti-inflammatory and anticancer effects[2]. Emodin is a potent selective 11β-HSD1 inhibitor with the IC50 of 186 and 86 nM for human and mouse 11β-HSD1, respectively. Emodin ameliorates metabolic disorder in diet-induced obese mice[3]. Emodin (Frangula emodin), an anthraquinone derivative, is an anti-SARS-CoV compound. Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 (ACE2) interaction[1]. Emodin inhibits casein kinase-2 (CK2). Anti-inflammatory and anticancer effects[2]. Emodin is a potent selective 11β-HSD1 inhibitor with the IC50 of 186 and 86 nM for human and mouse 11β-HSD1, respectively. Emodin ameliorates metabolic disorder in diet-induced obese mice[3].

   

Cytostipin

1-(tetrahydro-5-Hydroxy-4-methyl-3-furanyl)ethanone, 9ci

C7H12O3 (144.0786)


   

Stipitatonic acid

Stipitatonic acid

C9H4O6 (208.0008)


   

Botryodiplodin

Botryodiplodin

C7H12O3 (144.0786)


   

2-{[(5-hydroxy-2,5-dimethyl-4,6-dioxocyclohex-2-en-1-ylidene)amino]methyl}benzaldehyde

2-{[(5-hydroxy-2,5-dimethyl-4,6-dioxocyclohex-2-en-1-ylidene)amino]methyl}benzaldehyde

C16H15NO4 (285.1001)


   

1,1',4,4',5,5'-hexahydroxy-7,7'-dimethyl-[2,2'-bianthracene]-9,9',10,10'-tetrone

1,1',4,4',5,5'-hexahydroxy-7,7'-dimethyl-[2,2'-bianthracene]-9,9',10,10'-tetrone

C30H18O10 (538.09)


   

8,18-dihydroxy-3',4',10,16-tetramethyl-6,12,20-trioxo-5,21,25-trioxaspiro[octacyclo[13.10.2.1³,⁷.1³,¹³.0²,¹⁴.0¹⁹,²⁷.0²²,²⁶.0¹¹,²⁹]nonacosane-24,2'-oxolan]-1(26),2(14),7(29),8,10,15,17,19(27)-octaen-28-yl acetate

8,18-dihydroxy-3',4',10,16-tetramethyl-6,12,20-trioxo-5,21,25-trioxaspiro[octacyclo[13.10.2.1³,⁷.1³,¹³.0²,¹⁴.0¹⁹,²⁷.0²²,²⁶.0¹¹,²⁹]nonacosane-24,2'-oxolan]-1(26),2(14),7(29),8,10,15,17,19(27)-octaen-28-yl acetate

C35H30O11 (626.1788)


   

(3r,4r,6r,9r)-9-ethyl-3-(hydroxymethyl)-1,7-dioxaspiro[5.5]undecan-4-ol

(3r,4r,6r,9r)-9-ethyl-3-(hydroxymethyl)-1,7-dioxaspiro[5.5]undecan-4-ol

C12H22O4 (230.1518)


   

2-({[(5r)-5-hydroxy-2,5-dimethyl-4,6-dioxocyclohex-2-en-1-ylidene]amino}methyl)benzaldehyde

2-({[(5r)-5-hydroxy-2,5-dimethyl-4,6-dioxocyclohex-2-en-1-ylidene]amino}methyl)benzaldehyde

C16H15NO4 (285.1001)


   

(3s,4r,6r,9r)-9-ethyl-3-(hydroxymethyl)-1,7-dioxaspiro[5.5]undecan-4-ol

(3s,4r,6r,9r)-9-ethyl-3-(hydroxymethyl)-1,7-dioxaspiro[5.5]undecan-4-ol

C12H22O4 (230.1518)


   

(2s,3r,13s,14s,22s,23s,24r,27r,31s)-8,18-dihydroxy-14-methoxy-10,16,24-trimethyl-6,12,20-trioxo-5,21,26,28-tetraoxanonacyclo[13.13.2.1³,⁷.1³,¹³.0²,¹⁴.0¹⁹,³⁰.0²²,²⁹.0²³,²⁷.0¹¹,³²]dotriaconta-1(29),7,9,11(32),15,17,19(30)-heptaen-31-yl acetate

(2s,3r,13s,14s,22s,23s,24r,27r,31s)-8,18-dihydroxy-14-methoxy-10,16,24-trimethyl-6,12,20-trioxo-5,21,26,28-tetraoxanonacyclo[13.13.2.1³,⁷.1³,¹³.0²,¹⁴.0¹⁹,³⁰.0²²,²⁹.0²³,²⁷.0¹¹,³²]dotriaconta-1(29),7,9,11(32),15,17,19(30)-heptaen-31-yl acetate

C34H30O12 (630.1737)


   

15-(5,6-dimethylhept-3-en-2-yl)-10,14-dimethyl-2-oxapentacyclo[9.7.0.0¹,³.0⁵,¹⁰.0¹⁴,¹⁸]octadec-5-ene-4,7-dione

15-(5,6-dimethylhept-3-en-2-yl)-10,14-dimethyl-2-oxapentacyclo[9.7.0.0¹,³.0⁵,¹⁰.0¹⁴,¹⁸]octadec-5-ene-4,7-dione

C28H40O3 (424.2977)


   

(2r)-6-(benzylimino)-2-hydroxy-2,5-dimethylcyclohex-4-ene-1,3-dione

(2r)-6-(benzylimino)-2-hydroxy-2,5-dimethylcyclohex-4-ene-1,3-dione

C15H15NO3 (257.1052)


   

8,18-dihydroxy-14-methoxy-10,16,24-trimethyl-6,12,20-trioxo-5,21,26,28-tetraoxanonacyclo[13.13.2.1³,⁷.1³,¹³.0²,¹⁴.0¹⁹,³⁰.0²²,²⁹.0²³,²⁷.0¹¹,³²]dotriaconta-1(29),7,9,11(32),15,17,19(30)-heptaen-31-yl acetate

8,18-dihydroxy-14-methoxy-10,16,24-trimethyl-6,12,20-trioxo-5,21,26,28-tetraoxanonacyclo[13.13.2.1³,⁷.1³,¹³.0²,¹⁴.0¹⁹,³⁰.0²²,²⁹.0²³,²⁷.0¹¹,³²]dotriaconta-1(29),7,9,11(32),15,17,19(30)-heptaen-31-yl acetate

C34H30O12 (630.1737)


   

1,4,5,7-tetrahydroxy-2-methylanthracene-9,10-dione

1,4,5,7-tetrahydroxy-2-methylanthracene-9,10-dione

C15H10O6 (286.0477)


   

(3s,4s,6r,9r)-9-ethyl-3-(hydroxymethyl)-1,7-dioxaspiro[5.5]undecan-4-ol

(3s,4s,6r,9r)-9-ethyl-3-(hydroxymethyl)-1,7-dioxaspiro[5.5]undecan-4-ol

C12H22O4 (230.1518)


   

2-hydroxy-6-({[2-(hydroxymethyl)phenyl]methyl}imino)-2,5-dimethylcyclohex-4-ene-1,3-dione

2-hydroxy-6-({[2-(hydroxymethyl)phenyl]methyl}imino)-2,5-dimethylcyclohex-4-ene-1,3-dione

C16H17NO4 (287.1158)


   

(3s,3'r,4'r,13r,22s,24s,28s)-8,18-dihydroxy-3',4',10,16-tetramethyl-6,12,20-trioxo-5,21,25-trioxaspiro[octacyclo[13.10.2.1³,⁷.1³,¹³.0²,¹⁴.0¹⁹,²⁷.0²²,²⁶.0¹¹,²⁹]nonacosane-24,2'-oxolan]-1(26),2(14),7(29),8,10,15,17,19(27)-octaen-28-yl acetate

(3s,3'r,4'r,13r,22s,24s,28s)-8,18-dihydroxy-3',4',10,16-tetramethyl-6,12,20-trioxo-5,21,25-trioxaspiro[octacyclo[13.10.2.1³,⁷.1³,¹³.0²,¹⁴.0¹⁹,²⁷.0²²,²⁶.0¹¹,²⁹]nonacosane-24,2'-oxolan]-1(26),2(14),7(29),8,10,15,17,19(27)-octaen-28-yl acetate

C35H30O11 (626.1788)


   

(3r,4s,6r,9r)-9-ethyl-3-(hydroxymethyl)-1,7-dioxaspiro[5.5]undecan-4-ol

(3r,4s,6r,9r)-9-ethyl-3-(hydroxymethyl)-1,7-dioxaspiro[5.5]undecan-4-ol

C12H22O4 (230.1518)


   

(3r,4s,6s,9r)-9-ethyl-3-(hydroxymethyl)-1,7-dioxaspiro[5.5]undecan-4-ol

(3r,4s,6s,9r)-9-ethyl-3-(hydroxymethyl)-1,7-dioxaspiro[5.5]undecan-4-ol

C12H22O4 (230.1518)


   

(1s,2r,24r)-9,19-dihydroxy-13-methoxy-11,17-dimethyl-3,7,15,21-tetraoxo-6,22-dioxaheptacyclo[12.9.1.1¹,¹⁶.1⁴,⁸.0²,¹³.0¹²,²⁶.0²⁰,²⁵]hexacosa-4,8,10,12(26),16(25),17,19-heptaen-24-yl acetate

(1s,2r,24r)-9,19-dihydroxy-13-methoxy-11,17-dimethyl-3,7,15,21-tetraoxo-6,22-dioxaheptacyclo[12.9.1.1¹,¹⁶.1⁴,⁸.0²,¹³.0¹²,²⁶.0²⁰,²⁵]hexacosa-4,8,10,12(26),16(25),17,19-heptaen-24-yl acetate

C29H22O11 (546.1162)


   

5,6-dihydroxy-3-oxocyclohepta-1,4,6-triene-1-carboxylic acid

5,6-dihydroxy-3-oxocyclohepta-1,4,6-triene-1-carboxylic acid

C8H6O5 (182.0215)


   

(3s,4s,6s,9r)-9-ethyl-3-(hydroxymethyl)-1,7-dioxaspiro[5.5]undecan-4-ol

(3s,4s,6s,9r)-9-ethyl-3-(hydroxymethyl)-1,7-dioxaspiro[5.5]undecan-4-ol

C12H22O4 (230.1518)


   

(2r)-2-hydroxy-6-{[(4-hydroxy-2-methoxyphenyl)methyl]imino}-2,5-dimethylcyclohex-4-ene-1,3-dione

(2r)-2-hydroxy-6-{[(4-hydroxy-2-methoxyphenyl)methyl]imino}-2,5-dimethylcyclohex-4-ene-1,3-dione

C16H17NO5 (303.1107)


   

6-(benzylimino)-2-hydroxy-2,5-dimethylcyclohex-4-ene-1,3-dione

6-(benzylimino)-2-hydroxy-2,5-dimethylcyclohex-4-ene-1,3-dione

C15H15NO3 (257.1052)


   

2-hydroxy-6-{[(4-hydroxy-2-methoxyphenyl)methyl]imino}-2,5-dimethylcyclohex-4-ene-1,3-dione

2-hydroxy-6-{[(4-hydroxy-2-methoxyphenyl)methyl]imino}-2,5-dimethylcyclohex-4-ene-1,3-dione

C16H17NO5 (303.1107)


   

(2r)-2-hydroxy-6-({[2-(hydroxymethyl)phenyl]methyl}imino)-2,5-dimethylcyclohex-4-ene-1,3-dione

(2r)-2-hydroxy-6-({[2-(hydroxymethyl)phenyl]methyl}imino)-2,5-dimethylcyclohex-4-ene-1,3-dione

C16H17NO4 (287.1158)


   

(1r,3r,10r,11r,14r,15r,18r)-15-[(2r,3e,5r)-5,6-dimethylhept-3-en-2-yl]-10,14-dimethyl-2-oxapentacyclo[9.7.0.0¹,³.0⁵,¹⁰.0¹⁴,¹⁸]octadec-5-ene-4,7-dione

(1r,3r,10r,11r,14r,15r,18r)-15-[(2r,3e,5r)-5,6-dimethylhept-3-en-2-yl]-10,14-dimethyl-2-oxapentacyclo[9.7.0.0¹,³.0⁵,¹⁰.0¹⁴,¹⁸]octadec-5-ene-4,7-dione

C28H40O3 (424.2977)