NCBI Taxonomy: 2502083

Seseli transcaucasicum (ncbi_taxid: 2502083)

found 26 associated metabolites at species taxonomy rank level.

Ancestor: Seseli

Child Taxonomies: none taxonomy data.

Osthol

InChI=1/C15H16O3/c1-10(2)4-7-12-13(17-3)8-5-11-6-9-14(16)18-15(11)12/h4-6,8-9H,7H2,1-3H

C15H16O3 (244.1099386)


Osthol, also known as 7-methoxy-8-(3-methylpent-2-enyl)coumarin, belongs to coumarins and derivatives class of compounds. Those are polycyclic aromatic compounds containing a 1-benzopyran moiety with a ketone group at the C2 carbon atom (1-benzopyran-2-one). Osthol is practically insoluble (in water) and an extremely weak basic (essentially neutral) compound (based on its pKa). Osthol can be found in a number of food items such as wild celery, lemon, parsley, and wild carrot, which makes osthol a potential biomarker for the consumption of these food products. Osthol is an O-methylated coumarin. It is a calcium channel blocker, found in plants such as Cnidium monnieri, Angelica archangelica and Angelica pubescens . Osthole is a member of coumarins and a botanical anti-fungal agent. It has a role as a metabolite. Osthole is a natural product found in Murraya alata, Pentaceras australe, and other organisms with data available. See also: Angelica pubescens root (part of). D002317 - Cardiovascular Agents > D002121 - Calcium Channel Blockers D000077264 - Calcium-Regulating Hormones and Agents D049990 - Membrane Transport Modulators D007155 - Immunologic Factors Osthole (Osthol) is a natural antihistamine alternative. Osthole may be a potential inhibitor of histamine H1 receptor activity. Osthole also suppresses the secretion of HBV in cells. Osthole (Osthol) is a natural antihistamine alternative. Osthole may be a potential inhibitor of histamine H1 receptor activity. Osthole also suppresses the secretion of HBV in cells. Osthole (Osthol) is a natural antihistamine alternative. Osthole may be a potential inhibitor of histamine H1 receptor activity. Osthole also suppresses the secretion of HBV in cells.

   

Edultin

8-[2-(Acetyloxy)propan-2-yl]-2-oxo-2H,8H,9H-furo[2,3-H]chromen-9-yl (2Z)-2-methylbut-2-enoic acid

C21H22O7 (386.1365462)


Edultin is found in green vegetables. Edultin is a constituent of Angelica edulis

   

(+)-alpha-Bisabolol

(alphaR,1R)-alpha,4-Dimethyl-alpha-(4-methyl-3-penten-1-yl)-3-cyclohexene-1-methanol

C15H26O (222.1983546)


(+)-alpha-Bisabolol is found in German chamomile. (+)-alpha-Bisabolol is a constituent of the essential oil of Populus balsamifera (balsam poplar). Constituent of essential oil of Populus balsamifera (balsam poplar). (+)-alpha-Bisabolol is found in german camomile. alpha-Bisabolol is a nontoxic sesquiterpene alcohol present in natural essential oil, with anticancer activity. alpha-Bisabolol exerts selective anticancer effect on A549 NSCLC cells (IC50=15 μM) via induction of cell cycle arrest, mitochondrial apoptosis and inhibition of PI3K/Akt signalling pathways. alpha-Bisabolol also strongly induces apoptosis in glioma cells[1][2]. alpha-Bisabolol is a nontoxic sesquiterpene alcohol present in natural essential oil, with anticancer activity. alpha-Bisabolol exerts selective anticancer effect on A549 NSCLC cells (IC50=15 μM) via induction of cell cycle arrest, mitochondrial apoptosis and inhibition of PI3K/Akt signalling pathways. alpha-Bisabolol also strongly induces apoptosis in glioma cells[1][2].

   

alpha-Bisabolol

6-methyl-2-(4-methylcyclohex-3-en-1-yl)hept-5-en-2-ol

C15H26O (222.1983546)


alpha-Bisabolol is a nontoxic sesquiterpene alcohol present in natural essential oil, with anticancer activity. alpha-Bisabolol exerts selective anticancer effect on A549 NSCLC cells (IC50=15 μM) via induction of cell cycle arrest, mitochondrial apoptosis and inhibition of PI3K/Akt signalling pathways. alpha-Bisabolol also strongly induces apoptosis in glioma cells[1][2]. alpha-Bisabolol is a nontoxic sesquiterpene alcohol present in natural essential oil, with anticancer activity. alpha-Bisabolol exerts selective anticancer effect on A549 NSCLC cells (IC50=15 μM) via induction of cell cycle arrest, mitochondrial apoptosis and inhibition of PI3K/Akt signalling pathways. alpha-Bisabolol also strongly induces apoptosis in glioma cells[1][2].

   

Osthol

InChI=1/C15H16O3/c1-10(2)4-7-12-13(17-3)8-5-11-6-9-14(16)18-15(11)12/h4-6,8-9H,7H2,1-3H

C15H16O3 (244.1099386)


Osthole is a member of coumarins and a botanical anti-fungal agent. It has a role as a metabolite. Osthole is a natural product found in Murraya alata, Pentaceras australe, and other organisms with data available. See also: Angelica pubescens root (part of). A natural product found in Peucedanum ostruthium and Angelica pubescens. D002317 - Cardiovascular Agents > D002121 - Calcium Channel Blockers D000077264 - Calcium-Regulating Hormones and Agents D049990 - Membrane Transport Modulators D007155 - Immunologic Factors Origin: Plant, Coumarins Osthole (Osthol) is a natural antihistamine alternative. Osthole may be a potential inhibitor of histamine H1 receptor activity. Osthole also suppresses the secretion of HBV in cells. Osthole (Osthol) is a natural antihistamine alternative. Osthole may be a potential inhibitor of histamine H1 receptor activity. Osthole also suppresses the secretion of HBV in cells. Osthole (Osthol) is a natural antihistamine alternative. Osthole may be a potential inhibitor of histamine H1 receptor activity. Osthole also suppresses the secretion of HBV in cells.

   

Osthole

Osthole

C15H16O3 (244.1099386)


Annotation level-1

   

Acorenone

1,8-dimethyl-4-(propan-2-yl)spiro[4.5]dec-8-en-7-one

C15H24O (220.18270539999997)


   

bisabolol

alpha,4-Dimethyl-alpha-(4-methyl-3-penten-1-yl)-(alphaR,1R)-3-Cyclohexene-1-methanol

C15H26O (222.1983546)


alpha-Bisabolol is a nontoxic sesquiterpene alcohol present in natural essential oil, with anticancer activity. alpha-Bisabolol exerts selective anticancer effect on A549 NSCLC cells (IC50=15 μM) via induction of cell cycle arrest, mitochondrial apoptosis and inhibition of PI3K/Akt signalling pathways. alpha-Bisabolol also strongly induces apoptosis in glioma cells[1][2]. alpha-Bisabolol is a nontoxic sesquiterpene alcohol present in natural essential oil, with anticancer activity. alpha-Bisabolol exerts selective anticancer effect on A549 NSCLC cells (IC50=15 μM) via induction of cell cycle arrest, mitochondrial apoptosis and inhibition of PI3K/Akt signalling pathways. alpha-Bisabolol also strongly induces apoptosis in glioma cells[1][2].

   

Ostol

InChI=1\C15H16O3\c1-10(2)4-7-12-13(17-3)8-5-11-6-9-14(16)18-15(11)12\h4-6,8-9H,7H2,1-3H

C15H16O3 (244.1099386)


D002317 - Cardiovascular Agents > D002121 - Calcium Channel Blockers D000077264 - Calcium-Regulating Hormones and Agents D049990 - Membrane Transport Modulators D007155 - Immunologic Factors Osthole (Osthol) is a natural antihistamine alternative. Osthole may be a potential inhibitor of histamine H1 receptor activity. Osthole also suppresses the secretion of HBV in cells. Osthole (Osthol) is a natural antihistamine alternative. Osthole may be a potential inhibitor of histamine H1 receptor activity. Osthole also suppresses the secretion of HBV in cells. Osthole (Osthol) is a natural antihistamine alternative. Osthole may be a potential inhibitor of histamine H1 receptor activity. Osthole also suppresses the secretion of HBV in cells.

   

(1r,4s,5s)-1-isopropyl-4,8-dimethylspiro[4.5]dec-8-en-7-one

(1r,4s,5s)-1-isopropyl-4,8-dimethylspiro[4.5]dec-8-en-7-one

C15H24O (220.18270539999997)


   

2-[(6ar,8r,9r,9as)-9-(acetyloxy)-2-oxo-6ah,8h,9h,9ah-furo[2,3-h]chromen-8-yl]propan-2-yl (2r)-2-methylbutanoate

2-[(6ar,8r,9r,9as)-9-(acetyloxy)-2-oxo-6ah,8h,9h,9ah-furo[2,3-h]chromen-8-yl]propan-2-yl (2r)-2-methylbutanoate

C21H26O7 (390.1678446)


   

2-[9-(acetyloxy)-2-oxo-6ah,8h,9h,9ah-furo[2,3-h]chromen-8-yl]propan-2-yl 2-methylbutanoate

2-[9-(acetyloxy)-2-oxo-6ah,8h,9h,9ah-furo[2,3-h]chromen-8-yl]propan-2-yl 2-methylbutanoate

C21H26O7 (390.1678446)


   

2-{7-oxo-2h,3h-furo[3,2-g]chromen-2-yl}propan-2-yl (2e)-3-(4-hydroxyphenyl)prop-2-enoate

2-{7-oxo-2h,3h-furo[3,2-g]chromen-2-yl}propan-2-yl (2e)-3-(4-hydroxyphenyl)prop-2-enoate

C23H20O6 (392.125982)