NCBI Taxonomy: 213019

Sebastiania (ncbi_taxid: 213019)

found 24 associated metabolites at genus taxonomy rank level.

Ancestor: Hippomaneae

Child Taxonomies: Sebastiania cornuta, Sebastiania picardae, Sebastiania fruticosa, Sebastiania hexaptera, Sebastiania pavoniana, unclassified Sebastiania, Sebastiania brasiliensis, Sebastiania klotzschiana, Sebastiania commersoniana

Amyrin

(3S,4aR,5R,6aR,6bR,8S,8aR,12aR,14aR,14bR)-4,4,6a,6b,8a,11,11,14b-Octamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-eicosahydro-picen-3-ol

C30H50O (426.386145)


Beta-amyrin is a pentacyclic triterpenoid that is oleanane substituted at the 3beta-position by a hydroxy group and containing a double bond between positions 12 and 13. It is one of the most commonly occurring triterpenoids in higher plants. It has a role as a plant metabolite and an Aspergillus metabolite. It is a pentacyclic triterpenoid and a secondary alcohol. It derives from a hydride of an oleanane. beta-Amyrin is a natural product found in Ficus pertusa, Ficus septica, and other organisms with data available. See also: Calendula Officinalis Flower (part of); Viburnum opulus bark (part of); Centaurium erythraea whole (part of). A pentacyclic triterpenoid that is oleanane substituted at the 3beta-position by a hydroxy group and containing a double bond between positions 12 and 13. It is one of the most commonly occurring triterpenoids in higher plants. β-Amyrin, an ingredient of Celastrus hindsii, blocks amyloid β (Aβ)-induced long-term potentiation (LTP) impairment. β-amyrin is a promising candidate of treatment for AD[1]. β-Amyrin, an ingredient of Celastrus hindsii, blocks amyloid β (Aβ)-induced long-term potentiation (LTP) impairment. β-amyrin is a promising candidate of treatment for AD[1].

   

Xanthoxylin

Acetophenone, 2-hydroxy-4,6-dimethoxy- (8CI)

C10H12O4 (196.0735552)


obtained from Zanthoxylum piperitum (Japanese pepper tree) and Sapium sebiferum (Chinese tallowtree). Xanthoxylin is found in many foods, some of which are herbs and spices, german camomile, fats and oils, and pomegranate. Xanthoxylin is found in fats and oils. Xanthoxylin is obtained from Zanthoxylum piperitum (Japanese pepper tree) and Sapium sebiferum (Chinese tallowtree Xanthoxylin (Xanthoxyline) is isolated from Zanthoxylum simulans. Xanthoxylin (Xanthoxyline) has antifungal and antispasmodic activities[1][2]. Xanthoxylin (Xanthoxyline) is isolated from Zanthoxylum simulans. Xanthoxylin (Xanthoxyline) has antifungal and antispasmodic activities[1][2].

   

Glutinol

glutin-5-en-3beta-ol

C30H50O (426.386145)


   

Xanthoxylin

2 inverted exclamation mark -Hydroxy-4 inverted exclamation mark ,6 inverted exclamation mark -dimethoxyacetophenone

C10H12O4 (196.0735552)


obtained from Zanthoxylum piperitum (Japanese pepper tree) and Sapium sebiferum (Chinese tallowtree). Xanthoxylin is found in many foods, some of which are herbs and spices, german camomile, fats and oils, and pomegranate. Xanthoxylin is a carboxylic ester. It is functionally related to a phloroglucinol. Xanthoxylin is a natural product found in Euphorbia portulacoides, Pulicaria incisa, and other organisms with data available. Xanthoxylin is found in fats and oils. Xanthoxylin is obtained from Zanthoxylum piperitum (Japanese pepper tree) and Sapium sebiferum (Chinese tallowtree Xanthoxylin (Xanthoxyline) is isolated from Zanthoxylum simulans. Xanthoxylin (Xanthoxyline) has antifungal and antispasmodic activities[1][2]. Xanthoxylin (Xanthoxyline) is isolated from Zanthoxylum simulans. Xanthoxylin (Xanthoxyline) has antifungal and antispasmodic activities[1][2].

   

β-Amyrin

beta-amyrin-H2O

C30H50O (426.386145)


Beta-amyrin, also known as amyrin or (3beta)-olean-12-en-3-ol, is a member of the class of compounds known as triterpenoids. Triterpenoids are terpene molecules containing six isoprene units. Thus, beta-amyrin is considered to be an isoprenoid lipid molecule. Beta-amyrin is practically insoluble (in water) and an extremely weak acidic compound (based on its pKa). Beta-amyrin can be synthesized from oleanane. Beta-amyrin is also a parent compound for other transformation products, including but not limited to, erythrodiol, glycyrrhetaldehyde, and 24-hydroxy-beta-amyrin. Beta-amyrin can be found in a number of food items such as thistle, pepper (c. baccatum), wakame, and endive, which makes beta-amyrin a potential biomarker for the consumption of these food products. The amyrins are three closely related natural chemical compounds of the triterpene class. They are designated α-amyrin (ursane skeleton), β-amyrin (oleanane skeleton) and δ-amyrin. Each is a pentacyclic triterpenol with the chemical formula C30H50O. They are widely distributed in nature and have been isolated from a variety of plant sources such as epicuticular wax. In plant biosynthesis, α-amyrin is the precursor of ursolic acid and β-amyrin is the precursor of oleanolic acid. All three amyrins occur in the surface wax of tomato fruit. α-Amyrin is found in dandelion coffee . β-Amyrin, an ingredient of Celastrus hindsii, blocks amyloid β (Aβ)-induced long-term potentiation (LTP) impairment. β-amyrin is a promising candidate of treatment for AD[1]. β-Amyrin, an ingredient of Celastrus hindsii, blocks amyloid β (Aβ)-induced long-term potentiation (LTP) impairment. β-amyrin is a promising candidate of treatment for AD[1].

   
   

n-(2-oxotrideca-9,11-dien-1-yl)ethanimidic acid

n-(2-oxotrideca-9,11-dien-1-yl)ethanimidic acid

C15H25NO2 (251.188519)


   

4-[(1s,4r,10s,13s,16s,18r)-3,12,15,18-tetrahydroxy-10-[3-({[(1-hydroxyethylidene)amino]methanimidoyl}amino)propyl]-16-(3h-imidazol-4-ylmethyl)-9,20-dioxo-2,8,11,14,17-pentaazatricyclo[15.2.1.0⁴,⁸]icosa-2,11,14-trien-13-yl]butanoic acid

4-[(1s,4r,10s,13s,16s,18r)-3,12,15,18-tetrahydroxy-10-[3-({[(1-hydroxyethylidene)amino]methanimidoyl}amino)propyl]-16-(3h-imidazol-4-ylmethyl)-9,20-dioxo-2,8,11,14,17-pentaazatricyclo[15.2.1.0⁴,⁸]icosa-2,11,14-trien-13-yl]butanoic acid

C29H42N10O9 (674.3136082000001)


   

(3r,3as,5ar,5br,7ar,11ar,11br,13ar,13bs)-5a,5b,8,8,11a,13b-hexamethyl-3-(prop-1-en-2-yl)-tetradecahydro-1h-cyclopenta[a]chrysen-9-one

(3r,3as,5ar,5br,7ar,11ar,11br,13ar,13bs)-5a,5b,8,8,11a,13b-hexamethyl-3-(prop-1-en-2-yl)-tetradecahydro-1h-cyclopenta[a]chrysen-9-one

C30H48O (424.37049579999996)


   

(2s)-n-[(3s,6s,9s,13s,16s,19s)-3,13-dibenzyl-19-{[(2s)-2-(dimethylamino)-1-hydroxy-4-methylpentylidene]amino}-4,7,14,17-tetramethyl-6,16-bis(2-methylpropyl)-2,5,8,12,15,18-hexaoxo-1,11-dioxa-4,7,14,17-tetraazacycloicosan-9-yl]-2-(dimethylamino)-4-methylpentanimidic acid

(2s)-n-[(3s,6s,9s,13s,16s,19s)-3,13-dibenzyl-19-{[(2s)-2-(dimethylamino)-1-hydroxy-4-methylpentylidene]amino}-4,7,14,17-tetramethyl-6,16-bis(2-methylpropyl)-2,5,8,12,15,18-hexaoxo-1,11-dioxa-4,7,14,17-tetraazacycloicosan-9-yl]-2-(dimethylamino)-4-methylpentanimidic acid

C56H88N8O10 (1032.6623068)


   

n-(3,13-dibenzyl-19-{[2-(dimethylamino)-1-hydroxy-4-methylpentylidene]amino}-4,7,14,17-tetramethyl-6,16-bis(2-methylpropyl)-2,5,8,12,15,18-hexaoxo-1,11-dioxa-4,7,14,17-tetraazacycloicosan-9-yl)-2-(dimethylamino)-4-methylpentanimidic acid

n-(3,13-dibenzyl-19-{[2-(dimethylamino)-1-hydroxy-4-methylpentylidene]amino}-4,7,14,17-tetramethyl-6,16-bis(2-methylpropyl)-2,5,8,12,15,18-hexaoxo-1,11-dioxa-4,7,14,17-tetraazacycloicosan-9-yl)-2-(dimethylamino)-4-methylpentanimidic acid

C56H88N8O10 (1032.6623068)


   

n-[(9e,11e)-2-oxotrideca-9,11-dien-1-yl]ethanimidic acid

n-[(9e,11e)-2-oxotrideca-9,11-dien-1-yl]ethanimidic acid

C15H25NO2 (251.188519)


   

stigmast-5-en-3-ol, (3β)-

stigmast-5-en-3-ol, (3β)-

C29H50O (414.386145)


   

4-[(1s,4r,10s,13s,16s)-3,12,15,18-tetrahydroxy-10-[3-({[(1-hydroxyethylidene)amino]methanimidoyl}amino)propyl]-16-(3h-imidazol-4-ylmethyl)-9,20-dioxo-2,8,11,14,17-pentaazatricyclo[15.2.1.0⁴,⁸]icosa-2,11,14-trien-13-yl]butanoic acid

4-[(1s,4r,10s,13s,16s)-3,12,15,18-tetrahydroxy-10-[3-({[(1-hydroxyethylidene)amino]methanimidoyl}amino)propyl]-16-(3h-imidazol-4-ylmethyl)-9,20-dioxo-2,8,11,14,17-pentaazatricyclo[15.2.1.0⁴,⁸]icosa-2,11,14-trien-13-yl]butanoic acid

C29H42N10O9 (674.3136082000001)


   

(2s)-n-[(2r)-1-[(2s,4r)-4-hydroxy-2-[(1-{[(1r)-1-({1-[(2s,4r)-4-hydroxy-2-{[(1r)-1-methyl-1-{[(2r,3s)-3-methyl-1-oxo-1-{[(2r,3r,4r,5r)-1,2,4,5,6-pentahydroxyhexan-3-yl]oxy}pentan-2-yl]-c-hydroxycarbonimidoyl}propyl]-c-hydroxycarbonimidoyl}pyrrolidin-1-yl]-2-methyl-1-oxopropan-2-yl}-c-hydroxycarbonimidoyl)-1-methylpropyl]-c-hydroxycarbonimidoyl}-1-methylethyl)-c-hydroxycarbonimidoyl]pyrrolidin-1-yl]-2-methyl-1-oxobutan-2-yl]-2-({hydroxy[(2s,4r)-4-hydroxy-1-[(2s)-2-{[(2s)-1-hydroxy-2-({hydroxy[(2s,4r)-4-hydroxy-1-{2-[(1-hydroxyethylidene)amino]-2-methylpropanoyl}pyrrolidin-2-yl]methylidene}amino)-4-methylpentylidene]amino}-2-methylbutanoyl]pyrrolidin-2-yl]methylidene}amino)-4-methylpentanimidic acid

(2s)-n-[(2r)-1-[(2s,4r)-4-hydroxy-2-[(1-{[(1r)-1-({1-[(2s,4r)-4-hydroxy-2-{[(1r)-1-methyl-1-{[(2r,3s)-3-methyl-1-oxo-1-{[(2r,3r,4r,5r)-1,2,4,5,6-pentahydroxyhexan-3-yl]oxy}pentan-2-yl]-c-hydroxycarbonimidoyl}propyl]-c-hydroxycarbonimidoyl}pyrrolidin-1-yl]-2-methyl-1-oxopropan-2-yl}-c-hydroxycarbonimidoyl)-1-methylpropyl]-c-hydroxycarbonimidoyl}-1-methylethyl)-c-hydroxycarbonimidoyl]pyrrolidin-1-yl]-2-methyl-1-oxobutan-2-yl]-2-({hydroxy[(2s,4r)-4-hydroxy-1-[(2s)-2-{[(2s)-1-hydroxy-2-({hydroxy[(2s,4r)-4-hydroxy-1-{2-[(1-hydroxyethylidene)amino]-2-methylpropanoyl}pyrrolidin-2-yl]methylidene}amino)-4-methylpentylidene]amino}-2-methylbutanoyl]pyrrolidin-2-yl]methylidene}amino)-4-methylpentanimidic acid

C78H134N14O25 (1666.9644074)


   

4-{3,12,15,18-tetrahydroxy-10-[3-({[(1-hydroxyethylidene)amino]methanimidoyl}amino)propyl]-16-(3h-imidazol-4-ylmethyl)-9,20-dioxo-2,8,11,14,17-pentaazatricyclo[15.2.1.0⁴,⁸]icosa-2,11,14-trien-13-yl}butanoic acid

4-{3,12,15,18-tetrahydroxy-10-[3-({[(1-hydroxyethylidene)amino]methanimidoyl}amino)propyl]-16-(3h-imidazol-4-ylmethyl)-9,20-dioxo-2,8,11,14,17-pentaazatricyclo[15.2.1.0⁴,⁸]icosa-2,11,14-trien-13-yl}butanoic acid

C29H42N10O9 (674.3136082000001)