NCBI Taxonomy: 205932
Pezizomycotina incertae sedis (ncbi_taxid: 205932)
found 56 associated metabolites at no rank taxonomy rank level.
Ancestor: Pezizomycotina
Child Taxonomies: Cytoplea, Coma, Ordus, Lylea, Micula, Rutola, Wadeana, Guarroa, Trullula, Trizodia, Pinatubo, Dicoccum, Talekpea, Lacellina, Monodisma, Casaresia, Heliscina, Milospium, Patellina, Lomaantha, Hymenella, Mycosylva, Roigiella, Vanakripa, Vezdaeales, Badarisama, Chaetopsis, Nakatopsis, Clavariana, Deltopyxis, Dwayaangam, Coremiella, Everhartia, Eopyrenula, Heliscella, Miricatena, Hormiactis, Rhizohypha, Scopularia, Kiliophora, Geminoarcus, Asteromyces, Hormodochis, Arborispora, Inifatiella, Botryoderma, Mahabalella, Kramasamuha, Irpicomyces, Kodonospora, Resinogalea, Gilmaniella, Dendrospora, Ampullifera, Leptopeltis, Alysidiella, Virgariella, Cytosporina, Sarcosagium, Acrothecium, Helicoceras, Korunomyces, Melanophoma, Monosporium, Nematogonum, Staheliella, Sphaeronaema, Batistiaceae, Neopodoconis, Leptothyrium, Arcuadendron, Calyptrozyma, Hoehneliella, Slafractonia, Cheiromycina, Cryptophiale, Massariothea, Condylospora, Colletoconis, Cytosporella, Groveolopsis, Dissitimurus, Halysiomyces, Pleuropedium, Helicoubisia, Kumanasamuha, Gloeosporium, Diademospora, Myxosporella, Rhinotrichum, Thelocarpales, Actinocladium, Beauveriphora, Anguillospora, Pyramidospora, Gangliostilbe, Melanocephala, Digitodochium, Hyphodiscosia, Cooksonomyces, Cryptosporium, Culicidospora, Haplobasidion, Amblyosporium, Cacumisporium, Gonatobotryum, Sympodiophora, Agaricodochium, Koorchalomella, Phragmotrichum, Lateriramulosa, Neoheteroceras, Melanographium, Kostermansinda, Synnematomyces, Blastophorella, Diplocladiella, Heterocephalum, Rhinotrichella, Selenosporella, Isthmotricladia, Pseudodidymella, Solicorynespora, Sphaeriothyrium, Stephembruneria, Matsushimomyces, Paraphaeoisaria, Annellophorella, Pseudopatellina, Rhynchodiplodia, Sympodioclathra, Cryptophialoidea, Paracryptophiale, Coleodictyospora, Isthmolongispora, Dictyocatenulata, Proliferosphaera, Pleurotheciopsis, Pseudohansfordia, Leptomelanconium, Tetracoccosporium, Leucopenicillifer, Spondylocladiella, Enthallopycnidium, Paraceratocladium, Symbiotaphrinales, Alatosessilispora, Pseudophloeospora, Phialoarthrobotryum, Pseudoanguillospora, environmental samples
Swainsonine
Swainsonine is an indolizidine alkaloid isolated from the plant Swainsona canescens with three hydroxy substituents at positions 1, 2 and 8. It has a role as an antineoplastic agent, an immunological adjuvant, an EC 3.2.1.114 (mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase) inhibitor and a plant metabolite. An indolizidine alkaloid from the plant Swainsona canescens that is a potent alpha-mannosidase inhibitor. Swainsonine also exhibits antimetastatic, antiproliferative, and immunomodulatory activity. Swainsonine is a natural product found in Slafractonia leguminicola, Astragalus whitneyi, and other organisms with data available. Swainsonine is a plant toxin found in locoweed (families Fabaceae, Oxytropis, Astragalus and Swainsona) and some fungi (Metarhizium anisopliae, Rizoctonia leguminicola). It has been known to cause a potentially lethal central nervous system condition in livestock known as locoism and is a significant cause of economic losses in livestock industries. Along with slaframine, the other biologially active compound of R. leguminicola, it may contribute to a condition called "slobbers syndrome" in livestock that has ingested contaminated feed. (L1248, A3092) An indolizidine alkaloid from the plant Swainsona canescens that is a potent alpha-mannosidase inhibitor. Swainsonine also exhibits antimetastatic, antiproliferative, and immunomodulatory activity. An indolizidine alkaloid isolated from the plant Swainsona canescens with three hydroxy substituents at positions 1, 2 and 8. C308 - Immunotherapeutic Agent > C129820 - Antineoplastic Immunomodulating Agent > C2117 - Carbohydrate Processing Inhibitor C26170 - Protective Agent > C2459 - Chemoprotective Agent > C2080 - Cytoprotective Agent C471 - Enzyme Inhibitor > C2119 - Golgi Alpha-Mannosidase II Inhibitor C274 - Antineoplastic Agent > C2196 - Antimetastatic Agent D000970 - Antineoplastic Agents D007155 - Immunologic Factors D004791 - Enzyme Inhibitors
6-(2-formyl-6-hydroxy-4-methylphenoxy)-2-methoxy-3-(1-methoxy-3-methylbutyl)benzoic acid
3-[1-(acetyloxy)-3-methylbutyl]-6-(2-formyl-6-hydroxy-4-methylphenoxy)-2-methoxybenzoic acid
(3e,5e,7e,9e,11e,13e,15e,17e,19e)-21-oxodocosa-3,5,7,9,11,13,15,17,19-nonaenoic acid
(1r,6r,8s,9s,12r)-8,9-dihydroxy-6,11,11-trimethyl-7,10-dioxatetracyclo[7.4.0.0¹,¹².0⁴,⁸]tridec-3-en-2-one
n-[(1s)-1-(acetyloxy)-octahydroindolizin-6-yl]ethanimidic acid
(3r,6r)-3-benzyl-6-(hydroxymethyl)-1,4-dimethyl-3,6-bis(methylsulfanyl)piperazine-2,5-dione
C16H22N2O3S2 (354.10717819999996)
21-oxodocosa-3,5,7,9,11,13,15,17,19-nonaenoic acid
10-ethylidene-2-oxa-6-azatricyclo[5.3.0.0¹,³]dec-8-ene
(1s,3'r,4'r)-5'-{[(2s,3r,4s,5r)-6-{[(2e,4e,6e)-deca-2,4,6-trienoyloxy]methyl}-3,4,5-trihydroxyoxan-2-yl]oxy}-3',5,7-trihydroxy-6'-(hydroxymethyl)-3h-spiro[2-benzofuran-1,2'-oxan]-4'-yl (2e,4e,8e,10e,12e)-7-hydroxyhexadeca-2,4,8,10,12-pentaenoate
11,12-dihydroxy-6,14-dimethyl-1,7-dioxacyclotetradec-3-ene-2,8-dione
23-oxotetracosa-3,5,7,9,11,13,15,17,19,21-decaenoic acid
7-hydroxy-3-(7-hydroxy-2,2-dimethylchromen-8-yl)-6-methoxy-5-methyl-2-phenyl-3h-isoindol-1-one
(3r)-3-[(6r)-6-hydroxyheptyl]-5-methyl-3,4-dihydro-1h-2-benzopyran-6,8-diol
6-(2-formyl-6-hydroxy-4-methylphenoxy)-2-methoxy-3-[(1r)-3-methyl-1-(2-methylpropoxy)butyl]benzoic acid
5-chloro-4,12,12-trimethyl-3,13-dioxatricyclo[7.4.0.0²,⁶]trideca-1,4,6,8-tetraene-8,11-diol
(1s,3'r,4'r,5'r,6'r)-5'-{[(2s,3r,4s,5r)-6-{[(2e,4e,6e)-deca-2,4,6-trienoyloxy]methyl}-3,4,5-trihydroxyoxan-2-yl]oxy}-3',5,7-trihydroxy-6'-(hydroxymethyl)-3h-spiro[2-benzofuran-1,2'-oxan]-4'-yl (2e,4e,8e,10e,12e)-7-hydroxyhexadeca-2,4,8,10,12-pentaenoate
6-(2-formyl-6-hydroxy-4-methylphenoxy)-3-[(1s)-1-hydroxy-3-methylbutyl]-2-methoxybenzoic acid
3-[(1r)-1-(acetyloxy)-3-methylbutyl]-6-(2-formyl-6-hydroxy-4-methylphenoxy)-2-methoxybenzoic acid
(3z,6r,11r,12r,14r)-11,12-dihydroxy-6,14-dimethyl-1,7-dioxacyclotetradec-3-ene-2,8-dione
6-(2-formyl-6-hydroxy-4-methylphenoxy)-3-(1-hydroxy-3-methylbutyl)-2-methoxybenzoic acid
3-benzyl-6-(hydroxymethyl)-1,4-dimethyl-3,6-bis(methylsulfanyl)piperazine-2,5-dione
C16H22N2O3S2 (354.10717819999996)