NCBI Taxonomy: 162758

Distemonanthus (ncbi_taxid: 162758)

found 80 associated metabolites at genus taxonomy rank level.

Ancestor: Dialioideae

Child Taxonomies: Distemonanthus benthamianus

beta-Sitosterol

(3S,8S,9S,10R,13R,14S,17R)-17-((2R,5R)-5-ethyl-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol

C29H50O (414.386145)


beta-Sitosterol, a main dietary phytosterol found in plants, may have the potential for prevention and therapy for human cancer. Phytosterols are plant sterols found in foods such as oils, nuts, and vegetables. Phytosterols, in the same way as cholesterol, contain a double bond and are susceptible to oxidation, and are characterized by anti-carcinogenic and anti-atherogenic properties (PMID:13129445, 11432711). beta-Sitosterol is a phytopharmacological extract containing a mixture of phytosterols, with smaller amounts of other sterols, bonded with glucosides. These phytosterols are commonly derived from the South African star grass, Hypoxis rooperi, or from species of Pinus and Picea. The purported active constituent is termed beta-sitosterol. Additionally, the quantity of beta-sitosterol-beta-D-glucoside is often reported. Although the exact mechanism of action of beta-sitosterols is unknown, it may be related to cholesterol metabolism or anti-inflammatory effects (via interference with prostaglandin metabolism). Compared with placebo, beta-sitosterol improved urinary symptom scores and flow measures (PMID:10368239). A plant food-based diet modifies the serum beta-sitosterol concentration in hyperandrogenic postmenopausal women. This finding indicates that beta-sitosterol can be used as a biomarker of exposure in observational studies or as a compliance indicator in dietary intervention studies of cancer prevention (PMID:14652381). beta-Sitosterol induces apoptosis and activates key caspases in MDA-MB-231 human breast cancer cells (PMID:12579296). Sitosterol is a member of the class of phytosterols that is stigmast-5-ene substituted by a beta-hydroxy group at position 3. It has a role as a sterol methyltransferase inhibitor, an anticholesteremic drug, an antioxidant, a plant metabolite and a mouse metabolite. It is a 3beta-sterol, a stigmastane sterol, a 3beta-hydroxy-Delta(5)-steroid, a C29-steroid and a member of phytosterols. It derives from a hydride of a stigmastane. Active fraction of Solanum trilobatum; reduces side-effects of radiation-induced toxicity. Beta-Sitosterol is a natural product found in Elodea canadensis, Ophiopogon intermedius, and other organisms with data available. beta-Sitosterol is one of several phytosterols (plant sterols) with chemical structures similar to that of cholesterol. Sitosterols are white, waxy powders with a characteristic odor. They are hydrophobic and soluble in alcohols. beta-Sitosterol is found in many foods, some of which are ginseng, globe artichoke, sesbania flower, and common oregano. C1907 - Drug, Natural Product > C28178 - Phytosterol > C68437 - Unsaturated Phytosterol D057847 - Lipid Regulating Agents > D000960 - Hypolipidemic Agents D009676 - Noxae > D000963 - Antimetabolites Beta-Sitosterol (purity>98\\%) is a plant sterol. Beta-Sitosterol (purity>98\\%) interfere with multiple cell signaling pathways, including cell cycle, apoptosis, proliferation, survival, invasion, angiogenesis, metastasis and inflammation[1]. Beta-Sitosterol (purity>98\%) is a plant sterol. Beta-Sitosterol (purity>98\%) interfere with multiple cell signaling pathways, including cell cycle, apoptosis, proliferation, survival, invasion, angiogenesis, metastasis and inflammation[1].

   

Ayanin

4H-1-BENZOPYRAN-4-ONE, 5-HYDROXY-2-(3-HYDROXY-4-METHOXYPHENYL)-3,7-DIMETHOXY-

C18H16O7 (344.0895986)


3,5-dihydroxy-3,4,7-trimethoxyflavone is a trimethoxyflavone that is quercetin in which the hydroxy groups at positions 3, 4 and 7 have been replaced by methoxy groups. It has a role as a plant metabolite. It is a dihydroxyflavone and a trimethoxyflavone. It is functionally related to a quercetin. It is a conjugate acid of a 3,5-dihydroxy-3,4,7-trimethoxyflavone(1-). Ayanin is a natural product found in Psiadia viscosa, Solanum pubescens, and other organisms with data available. A trimethoxyflavone that is quercetin in which the hydroxy groups at positions 3, 4 and 7 have been replaced by methoxy groups.

   

Oxyanin A

Oxyayanin A

C18H16O8 (360.0845136)


A trihydroxyflavone that is flavone substituted by hydroxy groups at positioms 5, 2 and 5 and methoxy groups at positions 3, 7 and 4 respectively.

   
   
   

Benthamianin

3,4,8,10-Tetrahydroxy-9-methoxy- [ 2 ] benzopyrano [ 4,3-b ] [ 1 ] benzopyran-7 (5H) -one

C17H12O8 (344.0532152)


   

Distemonanthin

3,4,8,10-Tetrahydroxy-9-methoxy- [ 2 ] benzopyrano [ 4,3-b ] [ 1 ] benzopyran-5,7-dione

C17H10O9 (358.032481)


   

sitosterol

17-(5-ethyl-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol

C29H50O (414.386145)


A member of the class of phytosterols that is stigmast-5-ene substituted by a beta-hydroxy group at position 3. C1907 - Drug, Natural Product > C28178 - Phytosterol > C68437 - Unsaturated Phytosterol D057847 - Lipid Regulating Agents > D000960 - Hypolipidemic Agents D009676 - Noxae > D000963 - Antimetabolites Beta-Sitosterol (purity>98\\%) is a plant sterol. Beta-Sitosterol (purity>98\\%) interfere with multiple cell signaling pathways, including cell cycle, apoptosis, proliferation, survival, invasion, angiogenesis, metastasis and inflammation[1]. Beta-Sitosterol (purity>98\%) is a plant sterol. Beta-Sitosterol (purity>98\%) interfere with multiple cell signaling pathways, including cell cycle, apoptosis, proliferation, survival, invasion, angiogenesis, metastasis and inflammation[1].

   

5-Hydroxymorin

3,5,7,2,4,5-Hexahydroxyflavone

C15H10O8 (318.037566)


   

Benthamitin

3,5,6,7,2,4,5-Heptamethoxyflavone

C22H24O9 (432.14202539999997)


   

Chrysosplenol E

5,2-Dihydroxy-3,7,4,5-tetramethoxyflavone

C19H18O8 (374.1001628)


   

Distemonatin

5,6-Dihidroxy-3,7,2,4,5-pentamethoxyflavone

C20H20O9 (404.110727)


   

Oxyanin B

Oxyayanin B

C18H16O8 (360.0845136)


A trihydroxyflavone that is flavone substituted by hydroxy groups at positioms 5, 6 and 3 and methoxy groups at positions 3, 7 and 4 respectively.

   

Harzol

(3S,8S,9S,10R,13R,14S,17R)-17-[(2R,5R)-5-ethyl-6-methyl-heptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol

C29H50O (414.386145)


C1907 - Drug, Natural Product > C28178 - Phytosterol > C68437 - Unsaturated Phytosterol D057847 - Lipid Regulating Agents > D000960 - Hypolipidemic Agents D009676 - Noxae > D000963 - Antimetabolites Beta-Sitosterol (purity>98\\%) is a plant sterol. Beta-Sitosterol (purity>98\\%) interfere with multiple cell signaling pathways, including cell cycle, apoptosis, proliferation, survival, invasion, angiogenesis, metastasis and inflammation[1]. Beta-Sitosterol (purity>98\%) is a plant sterol. Beta-Sitosterol (purity>98\%) interfere with multiple cell signaling pathways, including cell cycle, apoptosis, proliferation, survival, invasion, angiogenesis, metastasis and inflammation[1].

   

Oxyayanin B

4H-1-Benzopyran-4-one, 5,6-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,7-dimethoxy-

C18H16O8 (360.0845136)


   

6-hydroxy-2-(2-hydroxy-4,5-dimethoxyphenyl)-3,5,7-trimethoxychromen-4-one

6-hydroxy-2-(2-hydroxy-4,5-dimethoxyphenyl)-3,5,7-trimethoxychromen-4-one

C20H20O9 (404.110727)


   

3,5,7-trimethoxy-2-(2,4,5-trimethoxyphenyl)chromen-4-one

3,5,7-trimethoxy-2-(2,4,5-trimethoxyphenyl)chromen-4-one

C21H22O8 (402.1314612)


   

2-(4-hydroxy-2,3-dimethoxyphenyl)-9-(5-hydroxy-2-methoxyphenyl)-3-(hydroxymethyl)-6,8-dimethoxy-2h,3h-[1,4]dioxino[2,3-h]chromen-7-one

2-(4-hydroxy-2,3-dimethoxyphenyl)-9-(5-hydroxy-2-methoxyphenyl)-3-(hydroxymethyl)-6,8-dimethoxy-2h,3h-[1,4]dioxino[2,3-h]chromen-7-one

C29H28O12 (568.1580688)


   

1,3,9,12-tetrahydroxy-2-methoxy-5,11-dioxatetraphene-8,10-dione

1,3,9,12-tetrahydroxy-2-methoxy-5,11-dioxatetraphene-8,10-dione

C17H10O9 (358.032481)


   

2-(4-hydroxy-3-methoxyphenyl)-3,5,7-trimethoxychromen-4-one

2-(4-hydroxy-3-methoxyphenyl)-3,5,7-trimethoxychromen-4-one

C19H18O7 (358.10524780000003)


   

3,5,6,7-tetrahydroxy-2-(2,3,4-trihydroxyphenyl)chromen-4-one

3,5,6,7-tetrahydroxy-2-(2,3,4-trihydroxyphenyl)chromen-4-one

C15H10O9 (334.032481)


   

5-hydroxy-3,7-dimethoxy-2-(2,3,4,6-tetramethoxyphenyl)chromen-4-one

5-hydroxy-3,7-dimethoxy-2-(2,3,4,6-tetramethoxyphenyl)chromen-4-one

C21H22O9 (418.1263762)


   

2-(2-hydroxy-4,5-dimethoxyphenyl)-3,5,7-trimethoxychromen-4-one

2-(2-hydroxy-4,5-dimethoxyphenyl)-3,5,7-trimethoxychromen-4-one

C20H20O8 (388.115812)


   

2-(3,4-dimethoxyphenyl)-5,6-dihydroxy-3,7-dimethoxychromen-4-one

2-(3,4-dimethoxyphenyl)-5,6-dihydroxy-3,7-dimethoxychromen-4-one

C19H18O8 (374.1001628)


   

5'-hydroxymorin

5'-hydroxymorin

C15H10O8 (318.037566)


   

2-(5-hydroxy-2,4-dimethoxyphenyl)-3,5,7-trimethoxychromen-4-one

2-(5-hydroxy-2,4-dimethoxyphenyl)-3,5,7-trimethoxychromen-4-one

C20H20O8 (388.115812)


   

stigmast-5-en-3-ol, (3β)-

stigmast-5-en-3-ol, (3β)-

C29H50O (414.386145)


   

5-hydroxy-3,7-dimethoxy-2-(2,4,5-trimethoxyphenyl)chromen-4-one

5-hydroxy-3,7-dimethoxy-2-(2,4,5-trimethoxyphenyl)chromen-4-one

C20H20O8 (388.115812)


   

(2r,3r)-2-(4-hydroxy-2,3-dimethoxyphenyl)-9-(5-hydroxy-2-methoxyphenyl)-3-(hydroxymethyl)-6,8-dimethoxy-2h,3h-[1,4]dioxino[2,3-h]chromen-7-one

(2r,3r)-2-(4-hydroxy-2,3-dimethoxyphenyl)-9-(5-hydroxy-2-methoxyphenyl)-3-(hydroxymethyl)-6,8-dimethoxy-2h,3h-[1,4]dioxino[2,3-h]chromen-7-one

C29H28O12 (568.1580688)