NCBI Taxonomy: 1392592

Codonopsis cordifolioidea (ncbi_taxid: 1392592)

found 30 associated metabolites at species taxonomy rank level.

Ancestor: Codonopsis

Child Taxonomies: none taxonomy data.

Coniferaldehyde

(E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enal

C10H10O3 (178.063)


Coniferaldehyde (CAS: 458-36-6), also known as 4-hydroxy-3-methoxycinnamaldehyde or ferulaldehyde, belongs to the class of organic compounds known as methoxyphenols. Methoxyphenols are compounds containing a methoxy group attached to the benzene ring of a phenol moiety. Coniferaldehyde is an extremely weak basic (essentially neutral) compound (based on its pKa). Outside of the human body, coniferaldehyde is found, on average, in the highest concentration within sherries. Coniferaldehyde has also been detected, but not quantified in, several different foods, such as highbush blueberries, lima beans, Chinese cabbages, loquats, and greenthread tea. This could make coniferaldehyde a potential biomarker for the consumption of these foods. BioTransformer predicts that coniferaldehyde is a product of caffeic aldehyde metabolism via a catechol-O-methylation-pattern2 reaction catalyzed by the enzyme catechol O-methyltransferase (PMID: 30612223). Coniferyl aldehyde, also known as 4-hydroxy-3-methoxycinnamaldehyde or 4-hm-ca, is a member of the class of compounds known as methoxyphenols. Methoxyphenols are compounds containing a methoxy group attached to the benzene ring of a phenol moiety. Coniferyl aldehyde is slightly soluble (in water) and a very weakly acidic compound (based on its pKa). Coniferyl aldehyde can be found in a number of food items such as pear, common walnut, kelp, and citrus, which makes coniferyl aldehyde a potential biomarker for the consumption of these food products. Coniferyl aldehyde is a low molecular weight phenolic compound susceptible to be extracted from cork stoppers into wine . Coniferyl aldehyde is a member of the class of cinnamaldehydes that is cinnamaldehyde substituted by a hydroxy group at position 4 and a methoxy group at position 3. It has a role as an antifungal agent and a plant metabolite. It is a member of cinnamaldehydes, a phenylpropanoid and a member of guaiacols. It is functionally related to an (E)-cinnamaldehyde. 4-Hydroxy-3-methoxycinnamaldehyde is a natural product found in Pandanus utilis, Microtropis japonica, and other organisms with data available. A member of the class of cinnamaldehydes that is cinnamaldehyde substituted by a hydroxy group at position 4 and a methoxy group at position 3. Acquisition and generation of the data is financially supported in part by CREST/JST. Coniferaldehyde (Ferulaldehyde) is an effective inducer of heme oxygenase-1 (HO-1). Coniferaldehyde exerts anti-inflammatory properties in response to LPS. Coniferaldehyde inhibits LPS-induced apoptosis through the PKCα/β II/Nrf-2/HO-1 dependent pathway in RAW264.7 macrophage cells[1]. Coniferaldehyde (Ferulaldehyde) is an effective inducer of heme oxygenase-1 (HO-1). Coniferaldehyde exerts anti-inflammatory properties in response to LPS. Coniferaldehyde inhibits LPS-induced apoptosis through the PKCα/β II/Nrf-2/HO-1 dependent pathway in RAW264.7 macrophage cells Coniferaldehyde. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=458-36-6 (retrieved 2024-09-04) (CAS RN: 458-36-6). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

   

Coniferin

(2R,3S,4S,5R,6S)-2-(Hydroxymethyl)-6-(4-((E)-3-hydroxyprop-1-en-1-yl)-2-methoxyphenoxy)tetrahydro-2H-pyran-3,4,5-triol

C16H22O8 (342.1315)


Coniferin (CAS: 531-29-3), also known as abietin or coniferoside, belongs to the class of organic compounds known as phenolic glycosides. These are organic compounds containing a phenolic structure attached to a glycosyl moiety. Some examples of phenolic structures include lignans and flavonoids. Among the sugar units found in natural glycosides are D-glucose, L-fructose, and L-rhamnose. Coniferin is an extremely weak basic (essentially neutral) compound (based on its pKa). Coniferin is a monosaccharide derivative consisting of coniferol attached to a beta-D-glucopyranosyl residue at position 1 via a glycosidic linkage. Coniferin is found in asparagus and has been isolated from Scorzonera hispanica (black salsify). Coniferin is a monosaccharide derivative that is coniferol attached to a beta-D-glucopyranosyl residue at position 1 via a glycosidic linkage. It has a role as a plant metabolite. It is a cinnamyl alcohol beta-D-glucoside, an aromatic ether and a monosaccharide derivative. It is functionally related to a coniferol. Coniferin is a natural product found in Salacia chinensis, Astragalus onobrychis, and other organisms with data available. A monosaccharide derivative that is coniferol attached to a beta-D-glucopyranosyl residue at position 1 via a glycosidic linkage. Isolated from Scorzonera hispanica (scorzonera) Coniferin (Laricin) is a glucoside of coniferyl alcohol. Coniferin inhibits fungal growth and melanization[1]. Coniferin (Laricin) is a glucoside of coniferyl alcohol. Coniferin inhibits fungal growth and melanization[1].

   

Sinapaldehyde

2-Propenal, 3-(4-hydroxy-3,5-dimethoxyphenyl)-, (2E)-

C11H12O4 (208.0736)


(E)-sinapaldehyde is a member of the class of cinnamaldehydes that is cinnamaldehyde substituted by a hydroxy group at position 4 and methoxy groups at positions 3 and 5. It has a role as an antifungal agent and a plant metabolite. It is a member of cinnamaldehydes, a dimethoxybenzene and a member of phenols. It is functionally related to an (E)-cinnamaldehyde. Sinapaldehyde is a natural product found in Stereospermum colais, Aralia bipinnata, and other organisms with data available. A member of the class of cinnamaldehydes that is cinnamaldehyde substituted by a hydroxy group at position 4 and methoxy groups at positions 3 and 5. D018501 - Antirheumatic Agents > D000894 - Anti-Inflammatory Agents, Non-Steroidal > D016861 - Cyclooxygenase Inhibitors D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics D000893 - Anti-Inflammatory Agents D004791 - Enzyme Inhibitors Sinapaldehyde, also known as (E)-3-(4-hydroxy-3,5-dimethoxyphenyl)-2-propenal or (E)-sinapoyl aldehyde, is a member of the class of compounds known as methoxyphenols. Methoxyphenols are compounds containing a methoxy group attached to the benzene ring of a phenol moiety. Sinapaldehyde is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). Sinapaldehyde can be synthesized from cinnamaldehyde. Sinapaldehyde can also be synthesized into 4-acetoxy-3,5-dimethoxy-trans-cinnamaldehyde. Sinapaldehyde can be found in a number of food items such as angelica, saskatoon berry, rubus (blackberry, raspberry), and lemon verbena, which makes sinapaldehyde a potential biomarker for the consumption of these food products. In Arabidopsis thaliana, this compound is part of the lignin biosynthesis pathway. The enzyme dihydroflavonol 4-reductase uses sinapaldehyde and NADPH to produce sinapyl alcohol and NADP+ . Annotation level-2 Sinapaldehyde exhibits moderate antibacterial against Methicillin resistant S. aureus (MRSA) and E. coli with MIC values of 128 and 128 μg/mL[1]. Sinapaldehyde exhibits moderate antibacterial against Methicillin resistant S. aureus (MRSA) and E. coli with MIC values of 128 and 128 μg/mL[1].

   

Dillapiol

1,3-Benzodioxole, 4,5-dimethoxy-6-(2-propenyl)- (9ci)

C12H14O4 (222.0892)


Dillapiol is found in coriander. Dillapiol is a constituent of Japanese, Indian (Anethum sowa) and European (Anethum graveolens) dill oils and Piper species Also from seeds of Bunium persicum (black caraway) Dillapiole is an organic chemical compound and essential oil commonly extracted from dill weed, though can be found in a variety of other plants Constituent of Japanese, Indian (Anethum sowa) and European (Anethum graveolens) dill oils and Piper subspecies Also from seeds of Bunium persicum (black caraway)

   

Lobetyolin

2-[(1,7-dihydroxytetradeca-4,12-dien-8,10-diyn-6-yl)oxy]-6-(hydroxymethyl)oxane-3,4,5-triol

C20H28O8 (396.1784)


   

Sinapaldehyde

3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enal

C11H12O4 (208.0736)


   

coniferyl aldehyde

4-Hydroxy-3-methoxy-trans-cinnamaldehyde

C10H10O3 (178.063)


Annotation level-1 Coniferaldehyde (Ferulaldehyde) is an effective inducer of heme oxygenase-1 (HO-1). Coniferaldehyde exerts anti-inflammatory properties in response to LPS. Coniferaldehyde inhibits LPS-induced apoptosis through the PKCα/β II/Nrf-2/HO-1 dependent pathway in RAW264.7 macrophage cells[1]. Coniferaldehyde (Ferulaldehyde) is an effective inducer of heme oxygenase-1 (HO-1). Coniferaldehyde exerts anti-inflammatory properties in response to LPS. Coniferaldehyde inhibits LPS-induced apoptosis through the PKCα/β II/Nrf-2/HO-1 dependent pathway in RAW264.7 macrophage cells[1].

   

Citrusin D

(2R,3R,4S,5S,6R)-2-[(E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoxy]-6-(hydroxymethyl)oxane-3,4,5-triol

C16H22O8 (342.1315)


(E)-Isoconiferin is a natural product found in Codonopsis cordifolioidea, Picea abies, and other organisms with data available.

   

Abietin

(2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-[4-[(E)-3-hydroxyprop-1-enyl]-2-methoxy-phenoxy]tetrahydropyran-3,4,5-triol

C16H22O8 (342.1315)


Coniferin (Laricin) is a glucoside of coniferyl alcohol. Coniferin inhibits fungal growth and melanization[1]. Coniferin (Laricin) is a glucoside of coniferyl alcohol. Coniferin inhibits fungal growth and melanization[1].

   
   

coniferaldehyde

coniferaldehyde

C10H10O3 (178.063)


CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 13

   

Sachaliside

Sachaliside

C15H20O7 (312.1209)


   

Ferulaldehyde

InChI=1\C10H10O3\c1-13-10-7-8(3-2-6-11)4-5-9(10)12\h2-7,12H,1H3\b3-2

C10H10O3 (178.063)


Coniferaldehyde (Ferulaldehyde) is an effective inducer of heme oxygenase-1 (HO-1). Coniferaldehyde exerts anti-inflammatory properties in response to LPS. Coniferaldehyde inhibits LPS-induced apoptosis through the PKCα/β II/Nrf-2/HO-1 dependent pathway in RAW264.7 macrophage cells[1]. Coniferaldehyde (Ferulaldehyde) is an effective inducer of heme oxygenase-1 (HO-1). Coniferaldehyde exerts anti-inflammatory properties in response to LPS. Coniferaldehyde inhibits LPS-induced apoptosis through the PKCα/β II/Nrf-2/HO-1 dependent pathway in RAW264.7 macrophage cells[1].

   

Dillapiol

Dillapiole

C12H14O4 (222.0892)


A natural product found in Anethum graveolens.

   

(2r,3s,4s,5r,6r)-2-(hydroxymethyl)-6-{[(4e,6r,12e)-1-hydroxytetradeca-4,12-dien-8,10-diyn-6-yl]oxy}oxane-3,4,5-triol

(2r,3s,4s,5r,6r)-2-(hydroxymethyl)-6-{[(4e,6r,12e)-1-hydroxytetradeca-4,12-dien-8,10-diyn-6-yl]oxy}oxane-3,4,5-triol

C20H28O7 (380.1835)


   

2-[(1,14-dihydroxytetradeca-6,12-dien-8,10-diyn-5-yl)oxy]-6-(hydroxymethyl)oxane-3,4,5-triol

2-[(1,14-dihydroxytetradeca-6,12-dien-8,10-diyn-5-yl)oxy]-6-(hydroxymethyl)oxane-3,4,5-triol

C20H28O8 (396.1784)


   

(2r,3r,4s,5s,6r)-2-{[(4e,6s,7r,12e)-1,7-dihydroxytetradeca-4,12-dien-8,10-diyn-6-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol

(2r,3r,4s,5s,6r)-2-{[(4e,6s,7r,12e)-1,7-dihydroxytetradeca-4,12-dien-8,10-diyn-6-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol

C20H28O8 (396.1784)


   

3-hydroxy-1-(2-hydroxy-4,5-dimethoxyphenyl)propan-1-one

3-hydroxy-1-(2-hydroxy-4,5-dimethoxyphenyl)propan-1-one

C11H14O5 (226.0841)


   

4,6-dimethoxy-5-(prop-2-en-1-yl)-2h-1,3-benzodioxole

4,6-dimethoxy-5-(prop-2-en-1-yl)-2h-1,3-benzodioxole

C12H14O4 (222.0892)


   

2-{[3-(4-hydroxy-3-methoxyphenyl)prop-2-en-1-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol

2-{[3-(4-hydroxy-3-methoxyphenyl)prop-2-en-1-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol

C16H22O8 (342.1315)


   

2-(hydroxymethyl)-6-[(1,7,14-trihydroxytetradeca-4,12-dien-8,10-diyn-6-yl)oxy]oxane-3,4,5-triol

2-(hydroxymethyl)-6-[(1,7,14-trihydroxytetradeca-4,12-dien-8,10-diyn-6-yl)oxy]oxane-3,4,5-triol

C20H28O9 (412.1733)


   

(2r,3r,4s,5s,6r)-2-{[(2e)-3-(4-hydroxy-3-methoxyphenyl)prop-2-en-1-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol

(2r,3r,4s,5s,6r)-2-{[(2e)-3-(4-hydroxy-3-methoxyphenyl)prop-2-en-1-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol

C16H22O8 (342.1315)


   

2-(hydroxymethyl)-6-[(1-hydroxytetradeca-4,12-dien-8,10-diyn-6-yl)oxy]oxane-3,4,5-triol

2-(hydroxymethyl)-6-[(1-hydroxytetradeca-4,12-dien-8,10-diyn-6-yl)oxy]oxane-3,4,5-triol

C20H28O7 (380.1835)


   

3-(2-hydroxy-4,5-dimethoxyphenyl)-3-oxopropyl acetate

3-(2-hydroxy-4,5-dimethoxyphenyl)-3-oxopropyl acetate

C13H16O6 (268.0947)


   

2-(hydroxymethyl)-6-{[3-(4-hydroxyphenyl)prop-2-en-1-yl]oxy}oxane-3,4,5-triol

2-(hydroxymethyl)-6-{[3-(4-hydroxyphenyl)prop-2-en-1-yl]oxy}oxane-3,4,5-triol

C15H20O7 (312.1209)


   

(4e,6s,7r,12e)-tetradeca-4,12-dien-8,10-diyne-1,6,7-triol

(4e,6s,7r,12e)-tetradeca-4,12-dien-8,10-diyne-1,6,7-triol

C14H18O3 (234.1256)


   

2-(3-methylbut-2-en-1-yl)-4-(prop-2-en-1-yl)phenol

2-(3-methylbut-2-en-1-yl)-4-(prop-2-en-1-yl)phenol

C14H18O (202.1358)


   

2-(hydroxymethyl)-6-[4-(3-hydroxyprop-1-en-1-yl)-2-methoxyphenoxy]oxane-3,4,5-triol

2-(hydroxymethyl)-6-[4-(3-hydroxyprop-1-en-1-yl)-2-methoxyphenoxy]oxane-3,4,5-triol

C16H22O8 (342.1315)


   

(2r,3s,4s,5r,6r)-2-(hydroxymethyl)-6-{[(4e,6s,7r,12e)-1,7,14-trihydroxytetradeca-4,12-dien-8,10-diyn-6-yl]oxy}oxane-3,4,5-triol

(2r,3s,4s,5r,6r)-2-(hydroxymethyl)-6-{[(4e,6s,7r,12e)-1,7,14-trihydroxytetradeca-4,12-dien-8,10-diyn-6-yl]oxy}oxane-3,4,5-triol

C20H28O9 (412.1733)


   

(2r,3r,4s,5s,6r)-2-{[(5r,6e,12e)-1,14-dihydroxytetradeca-6,12-dien-8,10-diyn-5-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol

(2r,3r,4s,5s,6r)-2-{[(5r,6e,12e)-1,14-dihydroxytetradeca-6,12-dien-8,10-diyn-5-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol

C20H28O8 (396.1784)