Gene Association: RCOR1

UniProt Search: RCOR1 (PROTEIN_CODING)
Function Description: REST corepressor 1

found 5 associated metabolites with current gene based on the text mining result from the pubmed database.

Benzamide

Trimethobenzamide hydrochloride

C7H7NO (121.0528)


Benzamide is an intermediate in the Benzoate degradation via CoA ligation. Benzamides are a class of chemical compounds derived from Benzamid, the carbonic acid amide of benzoic acid. In psychiatry some substituted benzamides are therapeutically used as neuroleptics and/or antipsychotics (wikipedia). Benzamide is an intermediate in the Benzoate degradation via CoA ligation. CONFIDENCE standard compound; INTERNAL_ID 8080 KEIO_ID B009 Benzamide (Benzenecarboxamide) is a potent poly(ADP-ribose) polymerase (PARP) inhibitor. Benzamide has protective activity against both glutamate- and methamphetamine (METH)-induced neurotoxicity in vitro. Benzamide can attenuate the METH-induced dopamine depletions and exhibits neuroprotective activity in mice, also has no acute effect on striatal dopamine metabolism and does not reduce body temperature[1].

   

cannabigerol

1,3-Benzenediol, 2-(3,7-dimethyl-2,6-octadienyl)-5-pentyl-, (E)-

C21H32O2 (316.2402)


A member of the class of resorcinols that is resorcinol which is substituted by a (2E)-3,7-dimethylocta-2,6-dien-1-yl group at position 2 and by a pentyl group at position 5. It is a natural product found in Cannabis sativa and Helichrysum species.

   

N-NITROSOMORPHOLINE

alpha-Acetoxy-N-nitrosomorpholine

C4H8N2O2 (116.0586)


CONFIDENCE standard compound; EAWAG_UCHEM_ID 3454 CONFIDENCE standard compound; INTERNAL_ID 4127 CONFIDENCE standard compound; INTERNAL_ID 8689 D009676 - Noxae > D002273 - Carcinogens D009676 - Noxae > D009153 - Mutagens

   

Benzamide

InChI=1\C7H7NO\c8-7(9)6-4-2-1-3-5-6\h1-5H,(H2,8,9

C7H7NO (121.0528)


Benzamide (Benzenecarboxamide) is a potent poly(ADP-ribose) polymerase (PARP) inhibitor. Benzamide has protective activity against both glutamate- and methamphetamine (METH)-induced neurotoxicity in vitro. Benzamide can attenuate the METH-induced dopamine depletions and exhibits neuroprotective activity in mice, also has no acute effect on striatal dopamine metabolism and does not reduce body temperature[1].

   

N-NITROSOMORPHOLINE

N-NITROSOMORPHOLINE

C4H8N2O2 (116.0586)


D009676 - Noxae > D002273 - Carcinogens D009676 - Noxae > D009153 - Mutagens