Chemical Formula: C8H15N3O3
Chemical Formula C8H15N3O3
Found 10 metabolite its formula value is C8H15N3O3
Dimethylguanidino valeric acid
Dimethylguanidino valeric acid or DMGV is a product formed from the transamination of asymmetric dimethylarginine (ADMA) via the enzyme alanine-glyoxylate aminotransferase 2 (AGXT2). This pathway is involved in nitric oxide regulation. DMGV has been detected in both blood and urine (PMID: 21945966 ). More recently DMGV has been identified as an independent plasma biomarker of nonalcoholic fatty liver disease (NAFLD). Furthermore, plasma DMGV levels are correlated with biopsy-proven nonalcoholic steatohepatitis (NASH). Plasma DMGV levels have also been found to decline in parallel with improvements in post-procedure cardiometabolic parameters. Plasma DMGV levels have been shown to be able to predict the development of type 2 diabetes up to 12 years before disease onset (PMID: 29083323). Baseline plasma levels of DMGV have been shown to be positively associated with body fat percentage, abdominal visceral fat, very low-density lipoprotein cholesterol (VLDL), and triglycerides. Plasma levels of DMGV are inversely associated with insulin sensitivity, low-density lipoprotein cholesterol, high-density lipoprotein size, and high-density lipoprotein cholesterol (HDL). Overall, DMGV is associated with partial resistance to metabolic health benefits of regular exercise (PMID: 31166569).
AMOZ
D000890 - Anti-Infective Agents > D023303 - Oxazolidinones
2-oxo-5-(3,3-Dimethylguanidine-1-yl)pentanoic acid
1,3-dihydroxy-2,2,4,4-tetramethyl-5-(nitrosomethylidene)imidazolidine
5-((Bis(methylamino)methylene)amino)-2-oxopentanoic acid
5-[[Amino(dimethylazaniumylidene)methyl]amino]-2-oxopentanoate
5-[[Methylamino(methylazaniumylidene)methyl]amino]-2-oxopentanoate
3-amino-5-morpholinomethyl-2-oxazolidinone
A member of the class of oxazolidinones that is 3-amino-1,3-oxazolidin-2-one substituted by a morpholin-4-ylmethyl group at position 5. It is the metabolite of furaltadone, a broad-spectrum antibacterial drug which was widely used as an additive in livestock and aquaculture feed.