Chemical Formula: C78H121N21O20

Chemical Formula C78H121N21O20

Found 4 metabolite its formula value is C78H121N21O20

Neurotensin

4-({1-[(6-amino-1-{2-[(4-carbamimidamido-1-{[5-carbamimidamido-1-(2-{[1-({1-[(1-carboxy-3-methylbutyl)-C-hydroxycarbonimidoyl]-2-methylbutyl}-C-hydroxycarbonimidoyl)-2-(4-hydroxyphenyl)ethyl]-C-hydroxycarbonimidoyl}pyrrolidin-1-yl)-1-oxopentan-2-yl]-C-hydroxycarbonimidoyl}butyl)-C-hydroxycarbonimidoyl]pyrrolidin-1-yl}-1-oxohexan-2-yl)-C-hydroxycarbonimidoyl]-2-(C-hydroxycarbonimidoyl)ethyl}-C-hydroxycarbonimidoyl)-4-({1-hydroxy-2-[(1-hydroxy-2-{[hydroxy(5-hydroxy-3,4-dihydro-2H-pyrrol-2-yl)methylidene]amino}-4-methylpentylidene)amino]-3-(4-hydroxyphenyl)propylidene}amino)butanoate

C78H121N21O20 (1671.9096306000001)


   

Neurotensin

Neurotensin acetate salt

C78H121N21O20 (1671.9096306000001)


A 13 amino acid peptide hormone which is found in the central nervous system and the gastrointestinal tract. It behaves as a neurotransmitter in the brain, as a hormone in the gut, and also as a neuromodulator. It is implicated in the pathophysiology of several CNS disorders (including schizophrenia, Parkinsons disease, drug abuse, pain, cancer, inflammation, eating disorders and central control of blood pressure) due to its association with a wide variety of neurotransmitter systems such as dopaminergic, sertonergic, glutamatergic, GABAergic, and cholinergic systems. Neurotensin, a gut tridecapeptide, acts as a potent cellular mitogen for various colorectal and pancreatic cancers which possess high-affinity neurotensin receptors (NTR).

   

(D-Tyr11)-Neurotensin

H-DL-Pyr-DL-Leu-DL-Tyr-DL-Glu-DL-Asn-DL-Lys-DL-Pro-DL-Arg-DL-Arg-DL-Pro-DL-Tyr-DL-xiIle-DL-Leu-OH

C78H121N21O20 (1671.9096306000001)


Neurotensin, a gut tridecapeptide, acts as a potent cellular mitogen for various colorectal and pancreatic cancers which possess high-affinity neurotensin receptors (NTR).

   

H-Pyr-D-Leu-Tyr-D-Glu-D-Asn-D-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH

H-Pyr-D-Leu-Tyr-D-Glu-D-Asn-D-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH

C78H121N21O20 (1671.9096306000001)