Chemical Formula: C49H57N11O6

Chemical Formula C49H57N11O6

Found 3 metabolite its formula value is C49H57N11O6

Biie-0246

5-Carbamimidamido-N-[2-(3,5-dioxo-1,2-diphenyl-1,2,4-triazolidin-4-yl)ethyl]-2-[(1-hydroxy-2-{1-[2-(4-{10-hydroxy-9-azatricyclo[9.4.0.0,]pentadeca-1(15),3,5,7,9,11,13-heptaen-2-yl}piperazin-1-yl)-2-oxoethyl]cyclopentyl}ethylidene)amino]pentanimidate

C49H57N11O6 (895.4493061999999)


   

5-(diaminomethylideneamino)-N-[2-(3,5-dioxo-1,2-diphenyl-1,2,4-triazolidin-4-yl)ethyl]-2-[[2-[1-[2-oxo-2-[4-(6-oxo-5,11-dihydrobenzo[c][1]benzazepin-11-yl)piperazin-1-yl]ethyl]cyclopentyl]acetyl]amino]pentanamide

5-(diaminomethylideneamino)-N-[2-(3,5-dioxo-1,2-diphenyl-1,2,4-triazolidin-4-yl)ethyl]-2-[[2-[1-[2-oxo-2-[4-(6-oxo-5,11-dihydrobenzo[c][1]benzazepin-11-yl)piperazin-1-yl]ethyl]cyclopentyl]acetyl]amino]pentanamide

C49H57N11O6 (895.4493061999999)


   

BIIE-0246

BIIE-0246

C49H57N11O6 (895.4493061999999)


BIIE-0246 (AR-H 053591) is a potent and selective NPY2R (neuropeptide Y receptor 2) antagonist with an IC50 value of 15 nM for rat [125I]PYY3-36. BIIE-0246 decreases the expression of p-AKT S473, P-p44/42 MAPK under the NPY-stimulated. BIIE-0246 reduces albuminuria in ADR nephropathy[1][2][3].