Chemical Formula: C47H65N11O7

Chemical Formula C47H65N11O7

Found 2 metabolite its formula value is C47H65N11O7

AcF-(OPdChaWR);AcF-(OPdChaWR);AcF-(OP(D-Cha)WR)

N-[3-(cyclohexylmethyl)-9-{3-[(diaminomethylidene)amino]propyl}-6-(1H-indol-3-ylmethyl)-1,4,7,10,16-pentaoxo-tetradecahydro-2H-pyrrolo[1,2-a]1,4,7,10,13-pentaazacyclooctadecan-15-yl]-2-acetamido-3-phenylpropanamide

C47H65N11O7 (895.5068180000001)

PMX-53

C47H65N11O7 (895.5068180000001)

PMX-53 (3D53) is a synthetic peptidic and a potent and orally active complement C5a receptor (CD88) antagonist with an IC50 of 20 nM. PMX-53 is also a low-affinity MrgX2 agonist that stimulates MrgX2-mediated mast cell degranulation. PMX-53 specifically binds to C5aR1 and does not bind to the second C5aR (C5L2) and C3aR. PMX-53 has anti-inflammatory, anticancer and antiatherosclerotic effects[1][2][3][4][5][6].