Chemical Formula: C37H60N7O17P3S
Chemical Formula C37H60N7O17P3S
Found 26 metabolite its formula value is C37H60N7O17P3S
(9Z,12Z)-hexadeca-9,12,15-trienoyl-CoA
C37H60N7O17P3S (999.2979100000001)
An unsaturated fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of (9Z,12Z)-hexadeca-9,12,15-trienoic acid.
(5E,8E,11E)-hexadeca-5,8,11-trienoyl-CoA
C37H60N7O17P3S (999.2979100000001)
(5e,8e,11e)-hexadeca-5,8,11-trienoyl-coa is an acyl-CoA or acyl-coenzyme A. More specifically, it is a (5E_8E_11E)-hexadeca-5_8_11-trienoic acid thioester of coenzyme A. (5e,8e,11e)-hexadeca-5,8,11-trienoyl-coa is an acyl-CoA with 10 fatty acid group as the acyl moiety attached to coenzyme A. Coenzyme A was discovered in 1946 by Fritz Lipmann (Journal of Biological Chemistry (1946) 162 (3): 743–744) and its structure was determined in the early 1950s at the Lister Institute in London. Coenzyme A is a complex, thiol-containing molecule that is naturally synthesized from pantothenate (vitamin B5), which is found in various foods such as meat, vegetables, cereal grains, legumes, eggs, and milk. More specifically, coenzyme A (CoASH or CoA) consists of a beta-mercaptoethylamine group linked to the vitamin pantothenic acid (B5) through an amide linkage and 3-phosphorylated ADP. Coenzyme A is synthesized in a five-step process that requires four molecules of ATP, pantothenate and cysteine. It is believed that there are more than 1100 types of acyl-CoA’s in the human body, which also corresponds to the number of acylcarnitines in the human body. Acyl-CoAs exists in all living species, ranging from bacteria to plants to humans. The general role of acyl-CoA’s is to assist in transferring fatty acids from the cytoplasm to mitochondria. This process facilitates the production of fatty acids in cells, which are essential in cell membrane structure. Acyl-CoAs are also susceptible to beta oxidation, forming, ultimately, acetyl-CoA. Acetyl-CoA can enter the citric acid cycle, eventually forming several equivalents of ATP. In this way, fats are converted to ATP -- or biochemical energy. Acyl-CoAs can be classified into 9 different categories depending on the size of their acyl-group: 1) short-chain acyl-CoAs; 2) medium-chain acyl-CoAs; 3) long-chain acyl-CoAs; and 4) very long-chain acyl-CoAs; 5) hydroxy acyl-CoAs; 6) branched chain acyl-CoAs; 7) unsaturated acyl-CoAs; 8) dicarboxylic acyl-CoAs and 9) miscellaneous acyl-CoAs. Short-chain acyl-CoAs have acyl-groups with two to four carbons (C2-C4), medium-chain acyl-CoAs have acyl-groups with five to eleven carbons (C5-C11), long-chain acyl-CoAs have acyl-groups with twelve to twenty carbons (C12-C20) while very long-chain acyl-CoAs have acyl groups with more than 20 carbons. (5e,8e,11e)-hexadeca-5,8,11-trienoyl-coa is therefore classified as a medium chain acyl-CoA. The oxidative degradation of fatty acids is a two-step process, catalyzed by acyl-CoA synthetase/synthase. Fatty acids are first converted to their acyl phosphate, the precursor to acyl-CoA. The latter conversion is mediated by acyl-CoA synthase. Three types of acyl-CoA synthases are employed, depending on the chain length of the fatty acid. (5e,8e,11e)-hexadeca-5,8,11-trienoyl-coa, being a medium chain acyl-CoA is a substrate for medium chain acyl-CoA synthase. The second step of fatty acid degradation is beta oxidation. Beta oxidation occurs in mitochondria and, in the case of very long chain acyl-CoAs, the peroxisome. After its formation in the cytosol, (5E,8E,11E)-hexadeca-5,8,11-trienoyl-CoA is transported into the mitochondria, the locus of beta oxidation. Transport of (5E,8E,11E)-hexadeca-5,8,11-trienoyl-CoA into the mitochondria requires carnitine palmitoyltransferase 1 (CPT1), which converts (5E,8E,11E)-hexadeca-5,8,11-trienoyl-CoA into (5E_8E_11E)-hexadeca-5_8_11-trienoylcarnitine, which gets transported into the mitochondrial matrix. Once in the matrix, (5E_8E_11E)-hexadeca-5_8_11-trienoylcarnitine is converted back to (5E,8E,11E)-hexadeca-5,8,11-trienoyl-CoA by CPT2, whereupon beta-oxidation can begin. Beta oxidation of (5E,8E,11E)-hexadeca-5,8,11-trienoyl-CoA occurs in four steps. First, since (5E,8E,11E)-hexadeca-5,8,11-trienoyl-CoA is a medium chain acyl-CoA it is the substrate for a medium chain acyl-CoA dehydrogenase, which catalyzes dehydrogenation of (5E,8E,11E)-hexadeca-5,8,11-trienoyl-CoA, creating a double bon...
hexadeca-7,10,13-trienoyl-CoA
C37H60N7O17P3S (999.2979100000001)
Hexadeca-7,10,13-trienoyl-coa is an acyl-CoA or acyl-coenzyme A. More specifically, it is a hexadeca-7_10_13-trienoic acid thioester of coenzyme A. Hexadeca-7,10,13-trienoyl-coa is an acyl-CoA with 16 fatty acid group as the acyl moiety attached to coenzyme A. Coenzyme A was discovered in 1946 by Fritz Lipmann (Journal of Biological Chemistry (1946) 162 (3): 743–744) and its structure was determined in the early 1950s at the Lister Institute in London. Coenzyme A is a complex, thiol-containing molecule that is naturally synthesized from pantothenate (vitamin B5), which is found in various foods such as meat, vegetables, cereal grains, legumes, eggs, and milk. More specifically, coenzyme A (CoASH or CoA) consists of a beta-mercaptoethylamine group linked to the vitamin pantothenic acid (B5) through an amide linkage and 3-phosphorylated ADP. Coenzyme A is synthesized in a five-step process that requires four molecules of ATP, pantothenate and cysteine. It is believed that there are more than 1100 types of acyl-CoA’s in the human body, which also corresponds to the number of acylcarnitines in the human body. Acyl-CoAs exists in all living species, ranging from bacteria to plants to humans. The general role of acyl-CoA’s is to assist in transferring fatty acids from the cytoplasm to mitochondria. This process facilitates the production of fatty acids in cells, which are essential in cell membrane structure. Acyl-CoAs are also susceptible to beta oxidation, forming, ultimately, acetyl-CoA. Acetyl-CoA can enter the citric acid cycle, eventually forming several equivalents of ATP. In this way, fats are converted to ATP -- or biochemical energy. Acyl-CoAs can be classified into 9 different categories depending on the size of their acyl-group: 1) short-chain acyl-CoAs; 2) medium-chain acyl-CoAs; 3) long-chain acyl-CoAs; and 4) very long-chain acyl-CoAs; 5) hydroxy acyl-CoAs; 6) branched chain acyl-CoAs; 7) unsaturated acyl-CoAs; 8) dicarboxylic acyl-CoAs and 9) miscellaneous acyl-CoAs. Short-chain acyl-CoAs have acyl-groups with two to four carbons (C2-C4), medium-chain acyl-CoAs have acyl-groups with five to eleven carbons (C5-C11), long-chain acyl-CoAs have acyl-groups with twelve to twenty carbons (C12-C20) while very long-chain acyl-CoAs have acyl groups with more than 20 carbons. Hexadeca-7,10,13-trienoyl-coa is therefore classified as a long chain acyl-CoA. The oxidative degradation of fatty acids is a two-step process, catalyzed by acyl-CoA synthetase/synthase. Fatty acids are first converted to their acyl phosphate, the precursor to acyl-CoA. The latter conversion is mediated by acyl-CoA synthase. Three types of acyl-CoA synthases are employed, depending on the chain length of the fatty acid. Hexadeca-7,10,13-trienoyl-coa, being a long chain acyl-CoA is a substrate for long chain acyl-CoA synthase. The second step of fatty acid degradation is beta oxidation. Beta oxidation occurs in mitochondria and, in the case of very long chain acyl-CoAs, the peroxisome. After its formation in the cytosol, hexadeca-7,10,13-trienoyl-CoA is transported into the mitochondria, the locus of beta oxidation. Transport of hexadeca-7,10,13-trienoyl-CoA into the mitochondria requires carnitine palmitoyltransferase 1 (CPT1), which converts hexadeca-7,10,13-trienoyl-CoA into hexadeca-7_10_13-trienoylcarnitine, which gets transported into the mitochondrial matrix. Once in the matrix, hexadeca-7_10_13-trienoylcarnitine is converted back to hexadeca-7,10,13-trienoyl-CoA by CPT2, whereupon beta-oxidation can begin. Beta oxidation of hexadeca-7,10,13-trienoyl-CoA occurs in four steps. First, since hexadeca-7,10,13-trienoyl-CoA is a long chain acyl-CoA it is the substrate for a long chain acyl-CoA dehydrogenase, which catalyzes dehydrogenation of hexadeca-7,10,13-trienoyl-CoA, creating a double bond between the alpha and beta carbons. FAD is the hydrogen acceptor, yielding FADH2. Second, Enoyl-CoA hydrase catalyzes the addition of water across the newly forme...
(6E,9E,12E)-hexadeca-6,9,12-trienoyl-CoA
C37H60N7O17P3S (999.2979100000001)
(6e,9e,12e)-hexadeca-6,9,12-trienoyl-coa is an acyl-CoA or acyl-coenzyme A. More specifically, it is a (6E_9E_12E)-hexadeca-6_9_12-trienoic acid thioester of coenzyme A. (6e,9e,12e)-hexadeca-6,9,12-trienoyl-coa is an acyl-CoA with 10 fatty acid group as the acyl moiety attached to coenzyme A. Coenzyme A was discovered in 1946 by Fritz Lipmann (Journal of Biological Chemistry (1946) 162 (3): 743–744) and its structure was determined in the early 1950s at the Lister Institute in London. Coenzyme A is a complex, thiol-containing molecule that is naturally synthesized from pantothenate (vitamin B5), which is found in various foods such as meat, vegetables, cereal grains, legumes, eggs, and milk. More specifically, coenzyme A (CoASH or CoA) consists of a beta-mercaptoethylamine group linked to the vitamin pantothenic acid (B5) through an amide linkage and 3-phosphorylated ADP. Coenzyme A is synthesized in a five-step process that requires four molecules of ATP, pantothenate and cysteine. It is believed that there are more than 1100 types of acyl-CoA’s in the human body, which also corresponds to the number of acylcarnitines in the human body. Acyl-CoAs exists in all living species, ranging from bacteria to plants to humans. The general role of acyl-CoA’s is to assist in transferring fatty acids from the cytoplasm to mitochondria. This process facilitates the production of fatty acids in cells, which are essential in cell membrane structure. Acyl-CoAs are also susceptible to beta oxidation, forming, ultimately, acetyl-CoA. Acetyl-CoA can enter the citric acid cycle, eventually forming several equivalents of ATP. In this way, fats are converted to ATP -- or biochemical energy. Acyl-CoAs can be classified into 9 different categories depending on the size of their acyl-group: 1) short-chain acyl-CoAs; 2) medium-chain acyl-CoAs; 3) long-chain acyl-CoAs; and 4) very long-chain acyl-CoAs; 5) hydroxy acyl-CoAs; 6) branched chain acyl-CoAs; 7) unsaturated acyl-CoAs; 8) dicarboxylic acyl-CoAs and 9) miscellaneous acyl-CoAs. Short-chain acyl-CoAs have acyl-groups with two to four carbons (C2-C4), medium-chain acyl-CoAs have acyl-groups with five to eleven carbons (C5-C11), long-chain acyl-CoAs have acyl-groups with twelve to twenty carbons (C12-C20) while very long-chain acyl-CoAs have acyl groups with more than 20 carbons. (6e,9e,12e)-hexadeca-6,9,12-trienoyl-coa is therefore classified as a medium chain acyl-CoA. The oxidative degradation of fatty acids is a two-step process, catalyzed by acyl-CoA synthetase/synthase. Fatty acids are first converted to their acyl phosphate, the precursor to acyl-CoA. The latter conversion is mediated by acyl-CoA synthase. Three types of acyl-CoA synthases are employed, depending on the chain length of the fatty acid. (6e,9e,12e)-hexadeca-6,9,12-trienoyl-coa, being a medium chain acyl-CoA is a substrate for medium chain acyl-CoA synthase. The second step of fatty acid degradation is beta oxidation. Beta oxidation occurs in mitochondria and, in the case of very long chain acyl-CoAs, the peroxisome. After its formation in the cytosol, (6E,9E,12E)-hexadeca-6,9,12-trienoyl-CoA is transported into the mitochondria, the locus of beta oxidation. Transport of (6E,9E,12E)-hexadeca-6,9,12-trienoyl-CoA into the mitochondria requires carnitine palmitoyltransferase 1 (CPT1), which converts (6E,9E,12E)-hexadeca-6,9,12-trienoyl-CoA into (6E_9E_12E)-hexadeca-6_9_12-trienoylcarnitine, which gets transported into the mitochondrial matrix. Once in the matrix, (6E_9E_12E)-hexadeca-6_9_12-trienoylcarnitine is converted back to (6E,9E,12E)-hexadeca-6,9,12-trienoyl-CoA by CPT2, whereupon beta-oxidation can begin. Beta oxidation of (6E,9E,12E)-hexadeca-6,9,12-trienoyl-CoA occurs in four steps. First, since (6E,9E,12E)-hexadeca-6,9,12-trienoyl-CoA is a medium chain acyl-CoA it is the substrate for a medium chain acyl-CoA dehydrogenase, which catalyzes dehydrogenation of (6E,9E,12E)-hexadeca-6,9,12-trienoyl-CoA, creating a double bon...
(4E,7E,10E)-hexadeca-4,7,10-trienoyl-CoA
C37H60N7O17P3S (999.2979100000001)
(4e,7e,10e)-hexadeca-4,7,10-trienoyl-coa is an acyl-CoA or acyl-coenzyme A. More specifically, it is a (4E_7E_10E)-hexadeca-4_7_10-trienoic acid thioester of coenzyme A. (4e,7e,10e)-hexadeca-4,7,10-trienoyl-coa is an acyl-CoA with 10 fatty acid group as the acyl moiety attached to coenzyme A. Coenzyme A was discovered in 1946 by Fritz Lipmann (Journal of Biological Chemistry (1946) 162 (3): 743–744) and its structure was determined in the early 1950s at the Lister Institute in London. Coenzyme A is a complex, thiol-containing molecule that is naturally synthesized from pantothenate (vitamin B5), which is found in various foods such as meat, vegetables, cereal grains, legumes, eggs, and milk. More specifically, coenzyme A (CoASH or CoA) consists of a beta-mercaptoethylamine group linked to the vitamin pantothenic acid (B5) through an amide linkage and 3-phosphorylated ADP. Coenzyme A is synthesized in a five-step process that requires four molecules of ATP, pantothenate and cysteine. It is believed that there are more than 1100 types of acyl-CoA’s in the human body, which also corresponds to the number of acylcarnitines in the human body. Acyl-CoAs exists in all living species, ranging from bacteria to plants to humans. The general role of acyl-CoA’s is to assist in transferring fatty acids from the cytoplasm to mitochondria. This process facilitates the production of fatty acids in cells, which are essential in cell membrane structure. Acyl-CoAs are also susceptible to beta oxidation, forming, ultimately, acetyl-CoA. Acetyl-CoA can enter the citric acid cycle, eventually forming several equivalents of ATP. In this way, fats are converted to ATP -- or biochemical energy. Acyl-CoAs can be classified into 9 different categories depending on the size of their acyl-group: 1) short-chain acyl-CoAs; 2) medium-chain acyl-CoAs; 3) long-chain acyl-CoAs; and 4) very long-chain acyl-CoAs; 5) hydroxy acyl-CoAs; 6) branched chain acyl-CoAs; 7) unsaturated acyl-CoAs; 8) dicarboxylic acyl-CoAs and 9) miscellaneous acyl-CoAs. Short-chain acyl-CoAs have acyl-groups with two to four carbons (C2-C4), medium-chain acyl-CoAs have acyl-groups with five to eleven carbons (C5-C11), long-chain acyl-CoAs have acyl-groups with twelve to twenty carbons (C12-C20) while very long-chain acyl-CoAs have acyl groups with more than 20 carbons. (4e,7e,10e)-hexadeca-4,7,10-trienoyl-coa is therefore classified as a medium chain acyl-CoA. The oxidative degradation of fatty acids is a two-step process, catalyzed by acyl-CoA synthetase/synthase. Fatty acids are first converted to their acyl phosphate, the precursor to acyl-CoA. The latter conversion is mediated by acyl-CoA synthase. Three types of acyl-CoA synthases are employed, depending on the chain length of the fatty acid. (4e,7e,10e)-hexadeca-4,7,10-trienoyl-coa, being a medium chain acyl-CoA is a substrate for medium chain acyl-CoA synthase. The second step of fatty acid degradation is beta oxidation. Beta oxidation occurs in mitochondria and, in the case of very long chain acyl-CoAs, the peroxisome. After its formation in the cytosol, (4E,7E,10E)-hexadeca-4,7,10-trienoyl-CoA is transported into the mitochondria, the locus of beta oxidation. Transport of (4E,7E,10E)-hexadeca-4,7,10-trienoyl-CoA into the mitochondria requires carnitine palmitoyltransferase 1 (CPT1), which converts (4E,7E,10E)-hexadeca-4,7,10-trienoyl-CoA into (4E_7E_10E)-hexadeca-4_7_10-trienoylcarnitine, which gets transported into the mitochondrial matrix. Once in the matrix, (4E_7E_10E)-hexadeca-4_7_10-trienoylcarnitine is converted back to (4E,7E,10E)-hexadeca-4,7,10-trienoyl-CoA by CPT2, whereupon beta-oxidation can begin. Beta oxidation of (4E,7E,10E)-hexadeca-4,7,10-trienoyl-CoA occurs in four steps. First, since (4E,7E,10E)-hexadeca-4,7,10-trienoyl-CoA is a medium chain acyl-CoA it is the substrate for a medium chain acyl-CoA dehydrogenase, which catalyzes dehydrogenation of (4E,7E,10E)-hexadeca-4,7,10-trienoyl-CoA, creating a double bon...
(7Z,11Z,14Z)-hexadeca-7,11,14-trienoyl-CoA
C37H60N7O17P3S (999.2979100000001)
(7z,11z,14z)-hexadeca-7,11,14-trienoyl-coa is an acyl-CoA or acyl-coenzyme A. More specifically, it is a (7Z_11Z_14Z)-hexadeca-7_11_14-trienoic acid thioester of coenzyme A. (7z,11z,14z)-hexadeca-7,11,14-trienoyl-coa is an acyl-CoA with 1 fatty acid group as the acyl moiety attached to coenzyme A. Coenzyme A was discovered in 1946 by Fritz Lipmann (Journal of Biological Chemistry (1946) 162 (3): 743–744) and its structure was determined in the early 1950s at the Lister Institute in London. Coenzyme A is a complex, thiol-containing molecule that is naturally synthesized from pantothenate (vitamin B5), which is found in various foods such as meat, vegetables, cereal grains, legumes, eggs, and milk. More specifically, coenzyme A (CoASH or CoA) consists of a beta-mercaptoethylamine group linked to the vitamin pantothenic acid (B5) through an amide linkage and 3-phosphorylated ADP. Coenzyme A is synthesized in a five-step process that requires four molecules of ATP, pantothenate and cysteine. It is believed that there are more than 1100 types of acyl-CoA’s in the human body, which also corresponds to the number of acylcarnitines in the human body. Acyl-CoAs exists in all living species, ranging from bacteria to plants to humans. The general role of acyl-CoA’s is to assist in transferring fatty acids from the cytoplasm to mitochondria. This process facilitates the production of fatty acids in cells, which are essential in cell membrane structure. Acyl-CoAs are also susceptible to beta oxidation, forming, ultimately, acetyl-CoA. Acetyl-CoA can enter the citric acid cycle, eventually forming several equivalents of ATP. In this way, fats are converted to ATP -- or biochemical energy. Acyl-CoAs can be classified into 9 different categories depending on the size of their acyl-group: 1) short-chain acyl-CoAs; 2) medium-chain acyl-CoAs; 3) long-chain acyl-CoAs; and 4) very long-chain acyl-CoAs; 5) hydroxy acyl-CoAs; 6) branched chain acyl-CoAs; 7) unsaturated acyl-CoAs; 8) dicarboxylic acyl-CoAs and 9) miscellaneous acyl-CoAs. Short-chain acyl-CoAs have acyl-groups with two to four carbons (C2-C4), medium-chain acyl-CoAs have acyl-groups with five to eleven carbons (C5-C11), long-chain acyl-CoAs have acyl-groups with twelve to twenty carbons (C12-C20) while very long-chain acyl-CoAs have acyl groups with more than 20 carbons. (7z,11z,14z)-hexadeca-7,11,14-trienoyl-coa is therefore classified as a short chain acyl-CoA. The oxidative degradation of fatty acids is a two-step process, catalyzed by acyl-CoA synthetase/synthase. Fatty acids are first converted to their acyl phosphate, the precursor to acyl-CoA. The latter conversion is mediated by acyl-CoA synthase. Three types of acyl-CoA synthases are employed, depending on the chain length of the fatty acid. (7z,11z,14z)-hexadeca-7,11,14-trienoyl-coa, being a short chain acyl-CoA is a substrate for short chain acyl-CoA synthase. The second step of fatty acid degradation is beta oxidation. Beta oxidation occurs in mitochondria and, in the case of very long chain acyl-CoAs, the peroxisome. After its formation in the cytosol, (7Z,11Z,14Z)-hexadeca-7,11,14-trienoyl-CoA is transported into the mitochondria, the locus of beta oxidation. Transport of (7Z,11Z,14Z)-hexadeca-7,11,14-trienoyl-CoA into the mitochondria requires carnitine palmitoyltransferase 1 (CPT1), which converts (7Z,11Z,14Z)-hexadeca-7,11,14-trienoyl-CoA into (7Z_11Z_14Z)-hexadeca-7_11_14-trienoylcarnitine, which gets transported into the mitochondrial matrix. Once in the matrix, (7Z_11Z_14Z)-hexadeca-7_11_14-trienoylcarnitine is converted back to (7Z,11Z,14Z)-hexadeca-7,11,14-trienoyl-CoA by CPT2, whereupon beta-oxidation can begin. Beta oxidation of (7Z,11Z,14Z)-hexadeca-7,11,14-trienoyl-CoA occurs in four steps. First, since (7Z,11Z,14Z)-hexadeca-7,11,14-trienoyl-CoA is a short chain acyl-CoA it is the substrate for a short chain acyl-CoA dehydrogenase, which catalyzes dehydrogenation of (7Z,11Z,14Z)-hexadeca-7,11,14-trienoyl-CoA,...
(4E,7E,13E)-hexadeca-4,7,13-trienoyl-CoA
C37H60N7O17P3S (999.2979100000001)
(4e,7e,13e)-hexadeca-4,7,13-trienoyl-coa is an acyl-CoA or acyl-coenzyme A. More specifically, it is a (4E_7E_13E)-hexadeca-4_7_13-trienoic acid thioester of coenzyme A. (4e,7e,13e)-hexadeca-4,7,13-trienoyl-coa is an acyl-CoA with 1 fatty acid group as the acyl moiety attached to coenzyme A. Coenzyme A was discovered in 1946 by Fritz Lipmann (Journal of Biological Chemistry (1946) 162 (3): 743–744) and its structure was determined in the early 1950s at the Lister Institute in London. Coenzyme A is a complex, thiol-containing molecule that is naturally synthesized from pantothenate (vitamin B5), which is found in various foods such as meat, vegetables, cereal grains, legumes, eggs, and milk. More specifically, coenzyme A (CoASH or CoA) consists of a beta-mercaptoethylamine group linked to the vitamin pantothenic acid (B5) through an amide linkage and 3-phosphorylated ADP. Coenzyme A is synthesized in a five-step process that requires four molecules of ATP, pantothenate and cysteine. It is believed that there are more than 1100 types of acyl-CoA’s in the human body, which also corresponds to the number of acylcarnitines in the human body. Acyl-CoAs exists in all living species, ranging from bacteria to plants to humans. The general role of acyl-CoA’s is to assist in transferring fatty acids from the cytoplasm to mitochondria. This process facilitates the production of fatty acids in cells, which are essential in cell membrane structure. Acyl-CoAs are also susceptible to beta oxidation, forming, ultimately, acetyl-CoA. Acetyl-CoA can enter the citric acid cycle, eventually forming several equivalents of ATP. In this way, fats are converted to ATP -- or biochemical energy. Acyl-CoAs can be classified into 9 different categories depending on the size of their acyl-group: 1) short-chain acyl-CoAs; 2) medium-chain acyl-CoAs; 3) long-chain acyl-CoAs; and 4) very long-chain acyl-CoAs; 5) hydroxy acyl-CoAs; 6) branched chain acyl-CoAs; 7) unsaturated acyl-CoAs; 8) dicarboxylic acyl-CoAs and 9) miscellaneous acyl-CoAs. Short-chain acyl-CoAs have acyl-groups with two to four carbons (C2-C4), medium-chain acyl-CoAs have acyl-groups with five to eleven carbons (C5-C11), long-chain acyl-CoAs have acyl-groups with twelve to twenty carbons (C12-C20) while very long-chain acyl-CoAs have acyl groups with more than 20 carbons. (4e,7e,13e)-hexadeca-4,7,13-trienoyl-coa is therefore classified as a short chain acyl-CoA. The oxidative degradation of fatty acids is a two-step process, catalyzed by acyl-CoA synthetase/synthase. Fatty acids are first converted to their acyl phosphate, the precursor to acyl-CoA. The latter conversion is mediated by acyl-CoA synthase. Three types of acyl-CoA synthases are employed, depending on the chain length of the fatty acid. (4e,7e,13e)-hexadeca-4,7,13-trienoyl-coa, being a short chain acyl-CoA is a substrate for short chain acyl-CoA synthase. The second step of fatty acid degradation is beta oxidation. Beta oxidation occurs in mitochondria and, in the case of very long chain acyl-CoAs, the peroxisome. After its formation in the cytosol, (4E,7E,13E)-hexadeca-4,7,13-trienoyl-CoA is transported into the mitochondria, the locus of beta oxidation. Transport of (4E,7E,13E)-hexadeca-4,7,13-trienoyl-CoA into the mitochondria requires carnitine palmitoyltransferase 1 (CPT1), which converts (4E,7E,13E)-hexadeca-4,7,13-trienoyl-CoA into (4E_7E_13E)-hexadeca-4_7_13-trienoylcarnitine, which gets transported into the mitochondrial matrix. Once in the matrix, (4E_7E_13E)-hexadeca-4_7_13-trienoylcarnitine is converted back to (4E,7E,13E)-hexadeca-4,7,13-trienoyl-CoA by CPT2, whereupon beta-oxidation can begin. Beta oxidation of (4E,7E,13E)-hexadeca-4,7,13-trienoyl-CoA occurs in four steps. First, since (4E,7E,13E)-hexadeca-4,7,13-trienoyl-CoA is a short chain acyl-CoA it is the substrate for a short chain acyl-CoA dehydrogenase, which catalyzes dehydrogenation of (4E,7E,13E)-hexadeca-4,7,13-trienoyl-CoA, creating a double bond betw...
(6Z,10Z,14Z)-hexadeca-6,10,14-trienoyl-CoA
C37H60N7O17P3S (999.2979100000001)
(6z,10z,14z)-hexadeca-6,10,14-trienoyl-coa is an acyl-CoA or acyl-coenzyme A. More specifically, it is a (6Z_10Z_14Z)-hexadeca-6_10_14-trienoic acid thioester of coenzyme A. (6z,10z,14z)-hexadeca-6,10,14-trienoyl-coa is an acyl-CoA with 1 fatty acid group as the acyl moiety attached to coenzyme A. Coenzyme A was discovered in 1946 by Fritz Lipmann (Journal of Biological Chemistry (1946) 162 (3): 743–744) and its structure was determined in the early 1950s at the Lister Institute in London. Coenzyme A is a complex, thiol-containing molecule that is naturally synthesized from pantothenate (vitamin B5), which is found in various foods such as meat, vegetables, cereal grains, legumes, eggs, and milk. More specifically, coenzyme A (CoASH or CoA) consists of a beta-mercaptoethylamine group linked to the vitamin pantothenic acid (B5) through an amide linkage and 3-phosphorylated ADP. Coenzyme A is synthesized in a five-step process that requires four molecules of ATP, pantothenate and cysteine. It is believed that there are more than 1100 types of acyl-CoA’s in the human body, which also corresponds to the number of acylcarnitines in the human body. Acyl-CoAs exists in all living species, ranging from bacteria to plants to humans. The general role of acyl-CoA’s is to assist in transferring fatty acids from the cytoplasm to mitochondria. This process facilitates the production of fatty acids in cells, which are essential in cell membrane structure. Acyl-CoAs are also susceptible to beta oxidation, forming, ultimately, acetyl-CoA. Acetyl-CoA can enter the citric acid cycle, eventually forming several equivalents of ATP. In this way, fats are converted to ATP -- or biochemical energy. Acyl-CoAs can be classified into 9 different categories depending on the size of their acyl-group: 1) short-chain acyl-CoAs; 2) medium-chain acyl-CoAs; 3) long-chain acyl-CoAs; and 4) very long-chain acyl-CoAs; 5) hydroxy acyl-CoAs; 6) branched chain acyl-CoAs; 7) unsaturated acyl-CoAs; 8) dicarboxylic acyl-CoAs and 9) miscellaneous acyl-CoAs. Short-chain acyl-CoAs have acyl-groups with two to four carbons (C2-C4), medium-chain acyl-CoAs have acyl-groups with five to eleven carbons (C5-C11), long-chain acyl-CoAs have acyl-groups with twelve to twenty carbons (C12-C20) while very long-chain acyl-CoAs have acyl groups with more than 20 carbons. (6z,10z,14z)-hexadeca-6,10,14-trienoyl-coa is therefore classified as a short chain acyl-CoA. The oxidative degradation of fatty acids is a two-step process, catalyzed by acyl-CoA synthetase/synthase. Fatty acids are first converted to their acyl phosphate, the precursor to acyl-CoA. The latter conversion is mediated by acyl-CoA synthase. Three types of acyl-CoA synthases are employed, depending on the chain length of the fatty acid. (6z,10z,14z)-hexadeca-6,10,14-trienoyl-coa, being a short chain acyl-CoA is a substrate for short chain acyl-CoA synthase. The second step of fatty acid degradation is beta oxidation. Beta oxidation occurs in mitochondria and, in the case of very long chain acyl-CoAs, the peroxisome. After its formation in the cytosol, (6Z,10Z,14Z)-hexadeca-6,10,14-trienoyl-CoA is transported into the mitochondria, the locus of beta oxidation. Transport of (6Z,10Z,14Z)-hexadeca-6,10,14-trienoyl-CoA into the mitochondria requires carnitine palmitoyltransferase 1 (CPT1), which converts (6Z,10Z,14Z)-hexadeca-6,10,14-trienoyl-CoA into (6Z_10Z_14Z)-hexadeca-6_10_14-trienoylcarnitine, which gets transported into the mitochondrial matrix. Once in the matrix, (6Z_10Z_14Z)-hexadeca-6_10_14-trienoylcarnitine is converted back to (6Z,10Z,14Z)-hexadeca-6,10,14-trienoyl-CoA by CPT2, whereupon beta-oxidation can begin. Beta oxidation of (6Z,10Z,14Z)-hexadeca-6,10,14-trienoyl-CoA occurs in four steps. First, since (6Z,10Z,14Z)-hexadeca-6,10,14-trienoyl-CoA is a short chain acyl-CoA it is the substrate for a short chain acyl-CoA dehydrogenase, which catalyzes dehydrogenation of (6Z,10Z,14Z)-hexadeca-6,10,14-trienoyl-CoA,...
(5E,8E,11E)-hexadeca-5,8,11-trienoyl-CoA
C37H60N7O17P3S (999.2979100000001)
(6E,9E,12E)-hexadeca-6,9,12-trienoyl-CoA
C37H60N7O17P3S (999.2979100000001)
(4E,7E,10E)-hexadeca-4,7,10-trienoyl-CoA
C37H60N7O17P3S (999.2979100000001)
(4E,7E,13E)-hexadeca-4,7,13-trienoyl-CoA
C37H60N7O17P3S (999.2979100000001)
(7Z,11Z,14Z)-hexadeca-7,11,14-trienoyl-CoA
C37H60N7O17P3S (999.2979100000001)
(6Z,10Z,14Z)-hexadeca-6,10,14-trienoyl-CoA
C37H60N7O17P3S (999.2979100000001)
S-[2-[3-[[(2R)-4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] (7Z,10Z,13Z)-hexadeca-7,10,13-trienethioate
C37H60N7O17P3S (999.2979100000001)
palmitoleoyl-CoA(4-)
C37H60N7O17P3S (999.2979100000001)
A hexadecenoyl-CoA(4-) obtained by deprotonation of the phosphate and diphosphate OH groups of palmitoleyl-CoA.
(7Z)-hexadecenoyl-CoA(4-)
C37H60N7O17P3S (999.2979100000001)
A monounsaturated fatty acyl-CoA(4-) obtained by deprotonation of the phosphate and diphosphate OH groups of (7Z)-hexadecenoyl-CoA; major species at pH 7.3.
(14E)-hexadecenoyl-CoA(4-)
C37H60N7O17P3S (999.2979100000001)
A monounsaturated fatty acyl-CoA(4-) arising from deprotonation of the phosphate and diphosphate OH groups of (14E)-hexadecenoyl-CoA; major species at pH 7.3.
(14Z)-hexadecenoyl-CoA(4-)
C37H60N7O17P3S (999.2979100000001)
A monounsaturated fatty acyl-CoA(4-) arising from deprotonation of the phosphate and diphosphate OH groups of (14Z)-hexadecenoyl-CoA; major species at pH 7.3.
(E)-2-methylpentadec-2-enoyl-CoA(4-)
C37H60N7O17P3S (999.2979100000001)
A monounsaturated fatty acyl-CoA(4-) obtained by deprotonation of the phosphate and diphosphate OH groups of (E)-2-methylpentadec-2-enoyl-CoA; major species at pH 7.3.
(6Z)-hexadecenoyl-CoA(4-)
C37H60N7O17P3S (999.2979100000001)
An acyl-CoA(4-) arising from deprotonation of the phosphate and diphosphate functions of (6Z)-hexadecenoyl-CoA.
(11Z)-hexadec-11-enoyl-CoA(4-)
C37H60N7O17P3S (999.2979100000001)
A monounsaturated fatty acyl-CoA(4-) obtained by deprotonation of the phosphate and diphosphate OH groups of (11Z)-hexadec-11-enoyl-CoA; major species at pH 7.3.
(E)-hexadec-2-enoyl-CoA(4-)
C37H60N7O17P3S (999.2979100000001)
A hexadecenoyl-CoA(4-) obtained by deprotonation of the phosphate and diphosphate OH groups of (E)-hexadec-2-enoyl-CoA; major species at pH 7.3.